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Gene: Rrp1 (ribosomal RNA processing 1) Rattus norvegicus

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Symbol:

Rrp1

Name:

ribosomal RNA processing 1

RGD ID:

1307286

Description:

Predicted to be involved in rRNA processing. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in nucleus. Orthologous to human RRP1 (ribosomal RNA processing 1); INTERACTS WITH (+)-schisandrin B; bisphenol A; cadmium dichloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC102553324; LOC309674; Nnp1; novel nuclear protein 1; ribosomal RNA processing 1 homolog; ribosomal RNA processing 1 homolog (S. cerevisiae); ribosomal RNA processing protein 1 homolog A; ribosomal RNA processing protein 1 homolog A-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RRP1 (ribosomal RNA processing 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rrp1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rrp1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RRP1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RRP1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rrp1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RRP1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RRP1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rrp1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rrp1 (ribosomal RNA processing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rrp1 (ribosomal RNA processing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RRP1 (ribosomal RNA processing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rrp1 (ribosomal RNA processing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rrp1 (ribosomal RNA processing 1)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rrp-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rrp-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nnp-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nnp-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RRP1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RRP1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rrp1b	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rrp1b	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	10,260,580 - 10,271,829 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	10,260,592 - 10,275,076 (+)	Ensembl				GRCr8
mRatBN7.2	20	10,260,892 - 10,272,141 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	10,260,870 - 10,272,144 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	10,960,606 - 10,971,992 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	10,321,511 - 10,332,899 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	10,793,007 - 10,804,213 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	10,982,016 - 10,993,260 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	10,981,998 - 10,993,280 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	13,153,171 - 13,164,414 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	10,594,298 - 10,606,945 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	11,772,182 - 11,782,114 (+)	NCBI		Celera
RGSC_v3.1	20	10,594,524 - 10,607,170 (+)	NCBI
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast ductal carcinoma (ISO)

invasive ductal carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

CGP 52608 (ISO)

choline (ISO)

chrysene (ISO)

deoxynivalenol (ISO)

dextran sulfate (ISO)

dicrotophos (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP)

hydrogen peroxide (ISO)

ivermectin (ISO)

L-methionine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methidathion (ISO)

N-methyl-4-phenylpyridinium (ISO)

nitrates (ISO)

phenobarbital (ISO)

resveratrol (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

Soman (EXP)

tetrachloromethane (EXP)

tetraphene (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

rRNA processing (IEA)

Cellular Component

chromosome (IBA,ISO)

nucleolus (ISO)

nucleus (IBA,IEA)

preribosome, small subunit precursor (IEA)

Molecular Function

protein binding (ISO)

transcription coactivator activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16780588	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Rrp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	10,260,580 - 10,271,829 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	10,260,592 - 10,275,076 (+)	Ensembl				GRCr8
mRatBN7.2	20	10,260,892 - 10,272,141 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	10,260,870 - 10,272,144 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	10,960,606 - 10,971,992 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	10,321,511 - 10,332,899 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	10,793,007 - 10,804,213 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	10,982,016 - 10,993,260 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	10,981,998 - 10,993,280 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	13,153,171 - 13,164,414 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	10,594,298 - 10,606,945 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	11,772,182 - 11,782,114 (+)	NCBI		Celera
RGSC_v3.1	20	10,594,524 - 10,607,170 (+)	NCBI
Cytogenetic Map	20	p12	NCBI

RRP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	43,789,577 - 43,805,293 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	43,789,513 - 43,805,757 (+)	Ensembl			hg38	GRCh38
GRCh37	21	45,209,458 - 45,225,174 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	44,033,846 - 44,048,411 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	21	30,315,012 - 30,329,580 (+)	NCBI		Celera
Cytogenetic Map	21	q22.3	NCBI
HuRef	21	30,577,333 - 30,592,003 (+)	NCBI		HuRef
CHM1_1	21	44,769,902 - 44,784,469 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	42,145,188 - 42,160,903 (+)	NCBI		T2T-CHM13v2.0

Rrp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	78,236,196 - 78,248,877 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	78,236,218 - 78,248,877 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	78,400,362 - 78,413,043 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	78,400,384 - 78,413,043 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	77,863,107 - 77,875,788 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	77,803,515 - 77,816,124 (-)	NCBI		MGSCv36	mm8
Celera	10	79,422,460 - 79,435,141 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Rrp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	41,456,191 - 41,466,856 (-)	Ensembl
ChiLan1.0	NW_004955407	41,456,291 - 41,466,040 (-)	NCBI	ChiLan1.0	ChiLan1.0

RRP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	39,795,085 - 39,809,725 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	34,645,683 - 34,660,316 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	30,045,143 - 30,061,243 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	43,343,784 - 43,358,401 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	43,343,786 - 43,358,401 (+)	Ensembl			panPan2	panpan1.1

RRP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	37,732,567 - 37,779,319 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	37,732,618 - 37,746,376 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	36,887,816 - 36,901,845 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	37,277,040 - 37,291,095 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	37,277,001 - 37,291,091 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	37,144,494 - 37,158,532 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	37,130,391 - 37,142,406 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	37,622,812 - 37,636,863 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rrp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	36,979,344 - 36,992,610 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936500	475,178 - 488,514 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936500	475,213 - 488,475 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RRP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	206,722,596 - 206,735,997 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	206,722,591 - 206,736,000 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RRP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	87,560,229 - 87,579,019 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	15,645,830 - 15,660,749 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rrp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	30,123,128 - 30,137,020 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624745	30,127,513 - 30,137,382 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rrp1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	1,690,567 - 1,701,522 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rrp1
104 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	95
Count of miRNA genes:	78
Interacting mature miRNAs:	86
Transcripts:	ENSRNOT00000001597
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	4189476	49189476	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	1	26925056	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1	33724594	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26128279	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8043920	29865039	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600300	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24164241	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	1	34066551	Rat
631265	Iresp1	Immunoglobin response QTL1	8.3		blood anti-double stranded DNA antibody amount (VT:0004762)	serum anti-DNA antibody level (CMO:0001533)	20	9041099	11115921	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29193376	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	1	27341128	Rat
1598870	Bp289	Blood pressure QTL 289	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	8216359	53216359	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29193376	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29193376	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29193376	Rat
1581577	Pur15	Proteinuria QTL 15	4.38	0.0002	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	20	8043920	15089182	Rat
1598858	Cm61	Cardiac mass QTL 61	3.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	20	8216359	53216359	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29193376	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1	14100378	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578510	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600300	Rat

Markers in Region

RH134029

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	10,271,946 - 10,272,138 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	10,993,066 - 10,993,257	NCBI	Rnor6.0
Rnor_5.0	20	13,164,220 - 13,164,411	UniSTS	Rnor5.0
RGSC_v3.4	20	10,606,751 - 10,606,942	UniSTS	RGSC3.4
Celera	20	11,781,920 - 11,782,111	UniSTS
RH 3.4 Map	20	154.36	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	65	160	91	90	59	92	59	6	354	190	11	139	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC087152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001597 ⟹ ENSRNOP00000001597

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	10,260,592 - 10,275,076 (+)	Ensembl
mRatBN7.2 Ensembl	20	10,260,879 - 10,272,140 (+)	Ensembl
Rnor_6.0 Ensembl	20	10,981,998 - 10,993,280 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095137 ⟹ ENSRNOP00000088687

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	10,260,870 - 10,272,143 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116425 ⟹ ENSRNOP00000092632

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	10,260,592 - 10,275,076 (+)	Ensembl
mRatBN7.2 Ensembl	20	10,260,879 - 10,272,140 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119562 ⟹ ENSRNOP00000086134

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	10,260,592 - 10,275,076 (+)	Ensembl
mRatBN7.2 Ensembl	20	10,260,903 - 10,272,144 (+)	Ensembl

RefSeq Acc Id:

NM_001012073 ⟹ NP_001012073

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	10,260,580 - 10,271,829 (+)	NCBI
mRatBN7.2	20	10,260,892 - 10,272,141 (+)	NCBI
Rnor_6.0	20	10,982,016 - 10,993,260 (+)	NCBI
Rnor_5.0	20	13,153,171 - 13,164,414 (+)	NCBI
RGSC_v3.4	20	10,594,298 - 10,606,945 (+)	RGD
Celera	20	11,772,182 - 11,782,114 (+)	NCBI

Sequence:

show sequence

AGCGCCCCAGCGGAGTGCGTGGTCTCAGGGTCCTGCTCACCATGGTTCCCGGAGTGCCGCTCCC
GCCGGAGATCCAGCTGGCGCAGCGTCTGGCGGGCAATGAGCAGGTGACGCGGGACCGCGCGTTA
CGGAAGCTGCAGAAGTACATCGTGGCCAGGAGTCAGCGAGCGACAGGTGGTTTTACTCCAGAGG
AGCTTCTAAAAGTATGGAAAGGACTGTTTTATTGCATGTGGATGCAGGACAAGCCCCTCCAGCA
GGAAGACCTAGGCAGGACCATTGCCCAGCTCGTCCATGCTTTTCAGACCACAGAGTCACAGCAC
CTGTTCCTGCGGGCCTTCTGGCAGACCATGATCCGAGAGTGGGTGGGCATCGACAGACTGCGTC
TGGATAAGTTCTACATGCTCATGAGGATGGTCCTGAGTGAGTCGCTGAAGGCTGTGAAAACCGG
AGGCTGGGAAGAGAGACAGATTGAGCAGCTGCTGCAGCTGCTGACCACCGAGATACTGAGCCCT
GACAGCCAGGCCCCCAATGGGGTGAAGAGCCACTTCCTAGAGATCTTTCTGGAGGAACTGACCA
AAGTGGGCGCTGCAGAGCTCACCGCAGACCAGAATCTGCAGTTCATCAAGCCCTTCTGCCAGAT
AGCAGCCCGCACTAAGGACTCCCTGGTTTTGCATAAGATCACTCAGAGCATCTTTGAGGCGATC
GTGGAACAGGCTCCCTTGGCCATAGAAGACCTCATGAATGAACTAGATGCACAGAGCGGAGAGG
GGGAAGGGTCAGACGAGGACGATGGTGATGATGACAGTGACGAGGCCTCAGAGGACGAGCAGGA
TCTGCAAGACACAGCTCCCAAGAATCAGCCTGCAGGCTCTGTAAGTAGGGCTGACCTTGAGGTG
GACGAGGAGGCGTGGGATGACGAGGAAGACACTGGCCCTGTCCTCCAGTTTGACTACGAGGCAG
TGGCTAACAAACTGTTCAAGCTGGCCAGTAGACAGAGCACCCCCTCTCAGAACCGGAAGCGCCT
CTACAAAGTGATCCAAAAGCTGCGGGACCTGGCTGGAGGCATTTTCCCTGAGGATGATGTCCCT
GAAAAAGCCTATAAGAAGCTGCTAGAAGGGAGGCGGAAACAGAAGAAGAAAAAGAAGCGCTTGC
CCACACTGCAGCCTCAGAATAAGGAAGGGGGGAGCGAGACAGAAGCCTCAAGTGCAGACCCAAG
CCGGGGAAGGAAGAGGAAGAGGAGCAGGAAGACTGATGAGAAGGCTGGCCAAAGAGGGCCTCCT
GGGAAGAGGAGGAAGCCCGGGGCTAGAGCCAAGGGGCCTAGGGTCCAGCAACCAAAGAGGAAGA
AGAAAGGATCATCACAGAGTGCGAAGTGAGGTGCACAGCCCAGGCCGGCTGGCCTCCTTACTGG
CATGAGGTGAATGGGGCCAGGCTCTCTGCGCATGCTCCTGCAGCCTCTGGATGCCAAGGCTCTG
AGCGCTCTATAGGGGAGGAGGATGAAAGAGGAGACCCCTGGTTAGTCCTGGCCTTCAGGAATGC
TCCTGCCTCAGCTATGGCCTGCATATCAGAAATTCATTCCGAACACTCAAAATTTTACTCGTAC
ATAGCTGTGGCTGTGCCTGATCCTGACCAGAGAGGCCAGAAGATCTGGAGACTGAGTCCAGCCT
GGGTCGTAGGGCAAAACCCTGTCTCCGCTTCCCTCCCCTACAGTAAGGAAAACAAAACTGAGTA
ACTGTGTGACCACCGTCAACTCCATCCTGGGCTGCCCACCAAATAAACTGCGGGACCTTACAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001012073	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87152	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001597
	ENSRNOP00000001597.5
	ENSRNOP00000086134.1
	ENSRNOP00000092632.1

RefSeq Acc Id:

NP_001012073 ⟸ NM_001012073

- UniProtKB:

Q5M9F3 (UniProtKB/TrEMBL), A0A8I6A1L6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVPGVPLPPEIQLAQRLAGNEQVTRDRALRKLQKYIVARSQRATGGFTPEELLKVWKGLFYCMW
MQDKPLQQEDLGRTIAQLVHAFQTTESQHLFLRAFWQTMIREWVGIDRLRLDKFYMLMRMVLSE
SLKAVKTGGWEERQIEQLLQLLTTEILSPDSQAPNGVKSHFLEIFLEELTKVGAAELTADQNLQ
FIKPFCQIAARTKDSLVLHKITQSIFEAIVEQAPLAIEDLMNELDAQSGEGEGSDEDDGDDDSD
EASEDEQDLQDTAPKNQPAGSVSRADLEVDEEAWDDEEDTGPVLQFDYEAVANKLFKLASRQST
PSQNRKRLYKVIQKLRDLAGGIFPEDDVPEKAYKKLLEGRRKQKKKKKRLPTLQPQNKEGGSET
EASSADPSRGRKRKRSRKTDEKAGQRGPPGKRRKPGARAKGPRVQQPKRKKKGSSQSAK

hide sequence

Ensembl Acc Id:

ENSRNOP00000001597 ⟸ ENSRNOT00000001597

Ensembl Acc Id:

ENSRNOP00000088687 ⟸ ENSRNOT00000095137

Ensembl Acc Id:

ENSRNOP00000092632 ⟸ ENSRNOT00000116425

Ensembl Acc Id:

ENSRNOP00000086134 ⟸ ENSRNOT00000119562

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5M9F3-F1-model_v2	AlphaFold	Q5M9F3	1-443	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701485

Promoter ID:

EPDNEW_R12009

Type:

initiation region

Name:

Rrp1_1

Description:

ribosomal RNA processing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	10,982,011 - 10,982,071	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307286	AgrOrtholog
BioCyc Gene	G2FUF-4284	BioCyc
Ensembl Genes	ENSRNOG00000001203	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001597	ENTREZGENE
	ENSRNOT00000001597.9	UniProtKB/TrEMBL
	ENSRNOT00000116425.2	UniProtKB/TrEMBL
	ENSRNOT00000119562.2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7132167	IMAGE-MGC_LOAD
InterPro	Nop52	UniProtKB/TrEMBL
KEGG Report	rno:309674	UniProtKB/TrEMBL
MGC_CLONE	MGC:95206	IMAGE-MGC_LOAD
NCBI Gene	309674	ENTREZGENE
PANTHER	Nop52	UniProtKB/TrEMBL
	RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG A	UniProtKB/TrEMBL
Pfam	Nop52	UniProtKB/TrEMBL
PhenoGen	Rrp1	PhenoGen
RatGTEx	ENSRNOG00000001203	RatGTEx
UniProt	A0A8I6A1L6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GJW2_RAT	UniProtKB/TrEMBL
	Q5M9F3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Rrp1	ribosomal RNA processing 1	LOC102553324	ribosomal RNA processing protein 1 homolog A-like	Data merged from RGD:7719570	737654	PROVISIONAL
2013-12-18	LOC102553324	ribosomal RNA processing protein 1 homolog A-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2013-07-12	Rrp1	ribosomal RNA processing 1	Rrp1	ribosomal RNA processing 1 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Rrp1	ribosomal RNA processing 1 homolog (S. cerevisiae)	Nnp1	novel nuclear protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Nnp1	novel nuclear protein 1	Nnp1_predicted	novel nuclear protein 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Nnp1_predicted	novel nuclear protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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