Lmod1 (leiomodin 1) - Rat Genome Database

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Gene: Lmod1 (leiomodin 1) Rattus norvegicus
Analyze
Symbol: Lmod1
Name: leiomodin 1
RGD ID: 1307236
Description: Predicted to enable tropomyosin binding activity. Predicted to be involved in actin cytoskeleton organization; muscle contraction; and positive regulation of actin filament polymerization. Located in actin filament and sarcomere. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human LMOD1 (leiomodin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leiomodin 1 (smooth muscle); leiomodin-1; LOC304816; SM-Lmod; smooth muscle leiomodin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,305,693 - 49,347,970 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1349,305,830 - 49,348,116 (+)EnsemblGRCr8
mRatBN7.21346,754,048 - 46,796,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,754,033 - 46,794,900 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1349,360,835 - 49,403,754 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,648,911 - 50,691,828 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,913,745 - 47,955,812 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,147,099 - 52,189,835 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,147,555 - 52,190,228 (+)Ensemblrn6Rnor6.0
Rnor_5.01357,197,722 - 57,240,449 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41348,321,458 - 48,364,610 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1347,074,647 - 47,116,198 (+)NCBICelera
RGSC_v3.11348,335,705 - 48,376,910 (+)NCBI
Cytogenetic Map13q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
Butylparaben  (ISO)
cadmium dichloride  (EXP)
CGP 52608  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
Cuprizon  (EXP)
D-glucose  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diuron  (EXP)
doramapimod  (EXP)
doxorubicin  (ISO)
fenamidone  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glucose  (ISO)
glycitein  (ISO)
glycitin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylparaben  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
perfluorohexanesulfonic acid  (ISO)
permethrin  (EXP,ISO)
picoxystrobin  (ISO)
progesterone  (ISO)
pyrimidifen  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
thifluzamide  (ISO)
titanium dioxide  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
actin filament  (IDA)
cytoskeleton  (IBA,IEA)
myofibril  (IBA,IEA,ISO)
sarcomere  (IDA,IEA)
striated muscle thin filament  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Localization of the human 64kD autoantigen D1 to myofibrils in a subset of extraocular muscle fibers. Conley CA and Fowler VM, Curr Eye Res. 1999 Oct;19(4):313-22.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22157009   PMID:26370058  


Genomics

Comparative Map Data
Lmod1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,305,693 - 49,347,970 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1349,305,830 - 49,348,116 (+)EnsemblGRCr8
mRatBN7.21346,754,048 - 46,796,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,754,033 - 46,794,900 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1349,360,835 - 49,403,754 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,648,911 - 50,691,828 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,913,745 - 47,955,812 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,147,099 - 52,189,835 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,147,555 - 52,190,228 (+)Ensemblrn6Rnor6.0
Rnor_5.01357,197,722 - 57,240,449 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41348,321,458 - 48,364,610 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1347,074,647 - 47,116,198 (+)NCBICelera
RGSC_v3.11348,335,705 - 48,376,910 (+)NCBI
Cytogenetic Map13q13NCBI
LMOD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381201,896,456 - 201,946,548 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1201,896,456 - 201,946,551 (-)Ensemblhg38GRCh38
GRCh371201,865,584 - 201,915,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,132,207 - 200,182,339 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341198,597,238 - 198,647,255NCBI
Celera1174,989,409 - 175,039,451 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,031,497 - 173,081,530 (-)NCBIHuRef
CHM1_11203,287,828 - 203,337,954 (-)NCBICHM1_1
T2T-CHM13v2.01201,154,211 - 201,204,217 (-)NCBIT2T-CHM13v2.0
Lmod1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,252,551 - 135,295,803 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,252,545 - 135,295,803 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381135,324,813 - 135,368,065 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,324,807 - 135,368,065 (+)Ensemblmm10GRCm38
MGSCv371137,221,390 - 137,264,642 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361137,141,224 - 137,184,476 (+)NCBIMGSCv36mm8
Celera1137,951,004 - 137,996,226 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.51NCBI
Lmod1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540637,964,643 - 38,013,405 (-)Ensembl
ChiLan1.0NW_00495540637,967,098 - 38,012,908 (-)NCBIChiLan1.0ChiLan1.0
LMOD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2147,427,412 - 47,486,137 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1147,392,121 - 47,450,834 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,493,627 - 177,543,853 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11181,795,634 - 181,845,543 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1181,798,304 - 181,845,295 (-)EnsemblpanPan2panpan1.1
LMOD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.171,025,022 - 1,059,254 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha71,076,436 - 1,111,697 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.071,032,621 - 1,067,903 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl71,032,679 - 1,067,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.171,020,621 - 1,055,864 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.071,128,814 - 1,164,077 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.071,152,832 - 1,188,079 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lmod1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934473,322,390 - 73,361,293 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365672,557,080 - 2,596,818 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365672,557,090 - 2,598,069 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMOD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,164,792 - 24,193,820 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11024,165,293 - 24,194,823 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LMOD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12527,460,230 - 27,511,667 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2527,460,460 - 27,511,024 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605528,242,522 - 28,295,376 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lmod1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,833,926 - 8,881,702 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248078,834,462 - 8,880,048 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Lmod1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v110355,525 - 397,050 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lmod1
241 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:89
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000009623
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134627292251216694Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134599007750392939Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134778041850392939Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
RH135433  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21346,794,618 - 46,794,815 (+)MAPPERmRatBN7.2
Rnor_6.01352,188,122 - 52,188,318NCBIRnor6.0
Rnor_5.01357,238,882 - 57,239,078UniSTSRnor5.0
RGSC_v3.41348,363,043 - 48,363,239UniSTSRGSC3.4
Celera1347,114,631 - 47,114,827UniSTS
RH 3.4 Map13162.9UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 154 91 90 59 32 59 6 288 132 11 133 74 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000084766   ⟹   ENSRNOP00000071399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,305,830 - 49,347,015 (+)Ensembl
mRatBN7.2 Ensembl1346,754,033 - 46,794,900 (+)Ensembl
Rnor_6.0 Ensembl1352,147,555 - 52,190,228 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000141000   ⟹   ENSRNOP00000103280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,338,385 - 49,347,015 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143549   ⟹   ENSRNOP00000107110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,305,830 - 49,346,194 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000154530   ⟹   ENSRNOP00000112841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,305,864 - 49,348,116 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173438   ⟹   ENSRNOP00000107818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,305,830 - 49,347,015 (+)Ensembl
RefSeq Acc Id: NM_001107179   ⟹   NP_001100649
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81349,305,845 - 49,347,970 (+)NCBI
mRatBN7.21346,754,048 - 46,796,186 (+)NCBI
Rnor_6.01352,147,568 - 52,189,689 (+)NCBI
Rnor_5.01357,197,722 - 57,240,449 (+)NCBI
RGSC_v3.41348,321,458 - 48,364,610 (+)RGD
Celera1347,074,647 - 47,116,198 (+)RGD
Sequence:
RefSeq Acc Id: XM_063272307   ⟹   XP_063128377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81349,305,693 - 49,346,677 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100649 (Get FASTA)   NCBI Sequence Viewer  
  NP_001417007 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128377 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A0A0G2K0D3 (Get FASTA)   NCBI Sequence Viewer  
  EDM09698 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071399
  ENSRNOP00000112841
RefSeq Acc Id: NP_001100649   ⟸   NM_001107179
- UniProtKB: A0A0G2K0D3 (UniProtKB/Swiss-Prot),   A6ICE9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071399   ⟸   ENSRNOT00000084766
RefSeq Acc Id: XP_063128377   ⟸   XM_063272307
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000107110   ⟸   ENSRNOT00000143549
Ensembl Acc Id: ENSRNOP00000112841   ⟸   ENSRNOT00000154530
Ensembl Acc Id: ENSRNOP00000107818   ⟸   ENSRNOT00000173438
Ensembl Acc Id: ENSRNOP00000103280   ⟸   ENSRNOT00000141000
Protein Domains
WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0D3-F1-model_v2 AlphaFold A0A0G2K0D3 1-595 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698843
Promoter ID:EPDNEW_R9367
Type:initiation region
Name:Lmod1_1
Description:leiomodin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01352,147,565 - 52,147,625EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307236 AgrOrtholog
BioCyc Gene G2FUF-18210 BioCyc
Ensembl Genes ENSRNOG00000051548 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000084766 ENTREZGENE
  ENSRNOT00000154530 ENTREZGENE
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot
InterPro L_dom-like UniProtKB/Swiss-Prot
  TMOD UniProtKB/Swiss-Prot
  WH2_dom UniProtKB/Swiss-Prot
NCBI Gene 304816 ENTREZGENE
PANTHER PTHR10901 UniProtKB/Swiss-Prot
  PTHR10901:SF5 UniProtKB/Swiss-Prot
Pfam Tropomodulin UniProtKB/Swiss-Prot
  WH2 UniProtKB/Swiss-Prot
PhenoGen Lmod1 PhenoGen
PROSITE WH2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000051548 RatGTEx
SMART WH2 UniProtKB/Swiss-Prot
Superfamily-SCOP RNI-like UniProtKB/Swiss-Prot
UniProt A0A0G2K0D3 ENTREZGENE
  A0A8L2R3Z2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L9K8_RAT UniProtKB/TrEMBL
  A0ABK0LEW0_RAT UniProtKB/TrEMBL
  A0ABK0LRV6_RAT UniProtKB/TrEMBL
  A6ICE9 ENTREZGENE, UniProtKB/TrEMBL
  LMOD1_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Lmod1  leiomodin 1  Lmod1  leiomodin 1 (smooth muscle)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Lmod1  leiomodin 1 (smooth muscle)   Lmod1_predicted  leiomodin 1 (smooth muscle) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lmod1_predicted  leiomodin 1 (smooth muscle) (predicted)      Symbol and Name status set to approved 70820 APPROVED