Zfp367 (zinc finger protein 367) - Rat Genome Database

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Gene: Zfp367 (zinc finger protein 367) Rattus norvegicus
Analyze
Symbol: Zfp367
Name: zinc finger protein 367
RGD ID: 1307136
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF367 (zinc finger protein 367); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC306695; Znf367
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817970,896 - 990,025 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl17970,741 - 990,029 (+)EnsemblGRCr8
mRatBN7.217965,161 - 984,290 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17965,161 - 984,287 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx17983,843 - 1,002,972 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,526,417 - 2,545,546 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.017981,263 - 1,000,392 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,652,892 - 1,672,021 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,652,895 - 1,672,021 (-)Ensemblrn6Rnor6.0
Rnor_5.0171,642,448 - 1,661,577 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4176,492,142 - 6,511,271 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera171,532,916 - 1,552,045 (-)NCBICelera
RGSC_v3.1176,492,141 - 6,511,268 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-butoxyethanol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
cefaloridine  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
copper(II) chloride  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
diethyl malate  (ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
glutathione  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
PhIP  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
senecionine  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tremolite asbestos  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15344908  


Genomics

Comparative Map Data
Zfp367
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817970,896 - 990,025 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl17970,741 - 990,029 (+)EnsemblGRCr8
mRatBN7.217965,161 - 984,290 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17965,161 - 984,287 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx17983,843 - 1,002,972 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,526,417 - 2,545,546 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.017981,263 - 1,000,392 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,652,892 - 1,672,021 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,652,895 - 1,672,021 (-)Ensemblrn6Rnor6.0
Rnor_5.0171,642,448 - 1,661,577 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4176,492,142 - 6,511,271 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera171,532,916 - 1,552,045 (-)NCBICelera
RGSC_v3.1176,492,141 - 6,511,268 (+)NCBI
Cytogenetic Map17p14NCBI
ZNF367
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38996,385,941 - 96,418,370 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl996,385,941 - 96,418,370 (-)Ensemblhg38GRCh38
GRCh37999,148,223 - 99,180,652 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,190,057 - 98,220,490 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34996,229,790 - 96,260,224NCBI
Celera969,589,805 - 69,622,246 (-)NCBICelera
Cytogenetic Map9q22.32NCBI
HuRef968,759,229 - 68,791,683 (-)NCBIHuRef
CHM1_1999,294,704 - 99,327,151 (-)NCBICHM1_1
T2T-CHM13v2.09108,557,662 - 108,590,090 (-)NCBIT2T-CHM13v2.0
Zfp367
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391364,280,836 - 64,301,013 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1364,280,832 - 64,301,016 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381364,133,022 - 64,153,199 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,133,018 - 64,153,202 (-)Ensemblmm10GRCm38
MGSCv371364,234,365 - 64,254,507 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361364,142,279 - 64,162,421 (-)NCBIMGSCv36mm8
Celera1365,797,078 - 65,816,476 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1333.26NCBI
Znf367
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542223,517,185 - 23,586,694 (+)Ensembl
ChiLan1.0NW_00495542223,516,950 - 23,535,882 (+)NCBIChiLan1.0ChiLan1.0
ZNF367
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21143,029,405 - 43,064,704 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1943,031,864 - 43,067,081 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0967,483,257 - 67,515,630 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1995,605,845 - 95,638,721 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl995,608,140 - 95,638,326 (-)EnsemblpanPan2panpan1.1
ZNF367
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1170,461,631 - 70,485,380 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl170,461,776 - 70,483,053 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha171,224,694 - 71,248,368 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0170,762,423 - 70,786,132 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl170,762,438 - 70,786,211 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1170,574,079 - 70,597,756 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0170,337,374 - 70,361,043 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0171,048,280 - 71,072,183 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znf367
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049446,117,474 - 6,130,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936487336,218 - 346,869 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936487333,952 - 347,465 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF367
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1025,707,722 - 25,735,067 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11025,707,711 - 25,735,073 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21030,034,258 - 30,043,140 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF367
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112106,712,962 - 106,743,351 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12106,713,310 - 106,741,040 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603895,113,777 - 95,145,018 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf367
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475318,146,067 - 18,164,534 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475318,145,862 - 18,166,732 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Znf367
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11475,398,245 - 75,417,631 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Zfp367
69 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:296
Count of miRNA genes:189
Interacting mature miRNAs:212
Transcripts:ENSRNOT00000036287
Prediction methods:Microtar, Miranda, Pita
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000036287   ⟹   ENSRNOP00000030325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17970,741 - 990,029 (+)Ensembl
mRatBN7.2 Ensembl17965,161 - 984,287 (+)Ensembl
Rnor_6.0 Ensembl171,652,895 - 1,672,021 (-)Ensembl
RefSeq Acc Id: NM_001012051   ⟹   NP_001012051
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817970,896 - 990,025 (+)NCBI
mRatBN7.217965,161 - 984,290 (+)NCBI
Rnor_6.0171,652,892 - 1,672,021 (-)NCBI
Rnor_5.0171,642,448 - 1,661,577 (-)NCBI
RGSC_v3.4176,492,142 - 6,511,271 (+)RGD
Celera171,532,916 - 1,552,045 (-)RGD
Sequence:
RefSeq Acc Id: XM_039095608   ⟹   XP_038951536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817971,628 - 990,025 (+)NCBI
mRatBN7.217966,193 - 984,290 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001012051 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951536 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85804 (Get FASTA)   NCBI Sequence Viewer  
  EDL84427 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030325
  ENSRNOP00000030325.4
GenBank Protein Q5U2Z0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012051   ⟸   NM_001012051
- UniProtKB: Q5U2Z0 (UniProtKB/Swiss-Prot),   A6KQD3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030325   ⟸   ENSRNOT00000036287
RefSeq Acc Id: XP_038951536   ⟸   XM_039095608
- Peptide Label: isoform X1
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2Z0-F1-model_v2 AlphaFold Q5U2Z0 1-340 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700262
Promoter ID:EPDNEW_R10784
Type:single initiation site
Name:Zfp367_1
Description:zinc finger protein 367
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0171,672,010 - 1,672,070EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307136 AgrOrtholog
BioCyc Gene G2FUF-10537 BioCyc
Ensembl Genes ENSRNOG00000027234 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000036287 ENTREZGENE
  ENSRNOT00000036287.5 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7111996 IMAGE-MGC_LOAD
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report rno:306695 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93863 IMAGE-MGC_LOAD
NCBI Gene 306695 ENTREZGENE
PANTHER TRANSCRIPTIONAL REPRESSOR PROTEIN YY UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 367 UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
  zf-C2H2_6 UniProtKB/Swiss-Prot
PhenoGen Zfp367 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000027234 RatGTEx
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt A6KQD3 ENTREZGENE, UniProtKB/TrEMBL
  Q5U2Z0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Zfp367  zinc finger protein 367  Zfp367_predicted  zinc finger protein 367 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Zfp367_predicted  zinc finger protein 367 (predicted)      Symbol and Name status set to approved 70820 APPROVED