Gene: Uimc1 (ubiquitin interaction motif containing 1) Rattus norvegicus
Analyze
Symbol:
Uimc1
Name:
ubiquitin interaction motif containing 1
RGD ID:
1307009
Description:
Predicted to enable several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; histone binding activity; and nuclear retinoid X receptor binding activity. Predicted to be involved in several processes, including DNA repair-dependent chromatin remodeling; mitotic G2 DNA damage checkpoint signaling; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleus. Predicted to be part of BRCA1-A complex. Predicted to be active in site of double-strand break. Orthologous to human UIMC1 (ubiquitin interaction motif containing 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; cadmium dichloride.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
BRCA1-A complex subunit RAP80; LOC290997; receptor-associated protein 80; RGD1307009; similar to retinoid x receptor interacting protein; ubiquitin interaction motif-containing protein 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 17 9,528,923 - 9,597,967 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 17 9,528,950 - 9,597,963 (+) Ensembl GRCr8 mRatBN7.2 17 9,523,793 - 9,592,810 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 17 9,527,794 - 9,592,799 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 17 9,545,179 - 9,610,171 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 17 11,074,182 - 11,139,282 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 17 9,541,582 - 9,606,574 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 17 10,061,915 - 10,130,921 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 17 10,065,947 - 10,130,907 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 17 12,169,049 - 12,239,764 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 17 15,579,709 - 15,644,888 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 17 9,605,684 - 9,670,784 (+) NCBI Celera RGSC_v3.1 17 15,579,708 - 15,644,885 (+) NCBI Cytogenetic Map 17 p14 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Uimc1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Uimc1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uimc1 Rat 1,2-dimethylhydrazine decreases expression ISO Uimc1 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of UIMC1 mRNA CTD PMID:22206623 Uimc1 Rat 17alpha-ethynylestradiol multiple interactions ISO Uimc1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UIMC1 mRNA CTD PMID:17942748 Uimc1 Rat 17alpha-ethynylestradiol increases expression ISO Uimc1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of UIMC1 mRNA CTD PMID:17555576|PMID:17942748 Uimc1 Rat 17beta-estradiol multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Estradiol co-treated with Norethindrone Acetate] results in increased expression of UIMC1 mRNA CTD PMID:22217510 Uimc1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Uimc1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uimc1 Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of UIMC1 mRNA CTD PMID:27291303 Uimc1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Uimc1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uimc1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Uimc1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UIMC1 mRNA CTD PMID:17942748 Uimc1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Uimc1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uimc1 Rat acrolein multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... CTD PMID:32699268 Uimc1 Rat aflatoxin B1 increases expression ISO Uimc1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of UIMC1 mRNA CTD PMID:19770486 Uimc1 Rat aflatoxin B1 increases expression ISO UIMC1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of UIMC1 mRNA CTD PMID:27153756 Uimc1 Rat all-trans-retinoic acid multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Tretinoin co-treated with arsenic trioxide] results in decreased expression of UIMC1 mRNA CTD PMID:15894607 Uimc1 Rat alpha-pinene multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... CTD PMID:32699268 Uimc1 Rat Aroclor 1254 decreases expression ISO Uimc1 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of UIMC1 mRNA CTD PMID:23650126 Uimc1 Rat arsane increases mutagenesis ISO UIMC1 (Homo sapiens) 6480464 Arsenic results in increased mutagenesis of UIMC1 gene CTD PMID:32920123 Uimc1 Rat arsenic atom increases mutagenesis ISO UIMC1 (Homo sapiens) 6480464 Arsenic results in increased mutagenesis of UIMC1 gene CTD PMID:32920123 Uimc1 Rat arsenous acid multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of UIMC1 mRNA CTD PMID:15894607 Uimc1 Rat benzo[a]pyrene diol epoxide I decreases expression ISO UIMC1 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of UIMC1 mRNA CTD PMID:19150397 Uimc1 Rat benzo[e]pyrene increases methylation ISO UIMC1 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of UIMC1 intron CTD PMID:30157460 Uimc1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of UIMC1 mRNA CTD PMID:26982218 Uimc1 Rat bisphenol A decreases expression ISO UIMC1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of UIMC1 mRNA CTD PMID:29275510 Uimc1 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of UIMC1 gene CTD PMID:28505145 Uimc1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of UIMC1 mRNA CTD PMID:25181051 Uimc1 Rat Bisphenol A diglycidyl ether affects splicing ISO Uimc1 (Mus musculus) 6480464 bisphenol A diglycidyl ether affects the splicing of UIMC1 mRNA CTD PMID:36464114 Uimc1 Rat bisphenol AF affects splicing ISO Uimc1 (Mus musculus) 6480464 bisphenol AF affects the splicing of UIMC1 mRNA CTD PMID:36464114 Uimc1 Rat bisphenol F decreases expression ISO Uimc1 (Mus musculus) 6480464 bisphenol F results in decreased expression of UIMC1 mRNA CTD PMID:38685157 Uimc1 Rat Butylbenzyl phthalate increases expression ISO Uimc1 (Mus musculus) 6480464 butylbenzyl phthalate results in increased expression of UIMC1 mRNA CTD PMID:28392331 Uimc1 Rat cadmium atom multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of UIMC1 more ... CTD PMID:35301059 Uimc1 Rat cadmium atom multiple interactions ISO Uimc1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of UIMC1 more ... CTD PMID:37236586 Uimc1 Rat cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of UIMC1 promoter CTD PMID:22457795 Uimc1 Rat cadmium dichloride multiple interactions ISO Uimc1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of UIMC1 more ... CTD PMID:37236586 Uimc1 Rat cadmium dichloride multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of UIMC1 more ... CTD PMID:35301059 Uimc1 Rat caffeine decreases phosphorylation ISO UIMC1 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of UIMC1 protein CTD PMID:35688186 Uimc1 Rat carbon nanotube increases expression ISO UIMC1 (Homo sapiens) 6480464 Nanotubes, Carbon analog results in increased expression of UIMC1 mRNA CTD PMID:25102311 Uimc1 Rat cisplatin multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of UIMC1 mRNA CTD PMID:30871063 Uimc1 Rat copper(II) sulfate decreases expression ISO UIMC1 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of UIMC1 mRNA CTD PMID:19549813 Uimc1 Rat coumarin increases phosphorylation ISO UIMC1 (Homo sapiens) 6480464 coumarin results in increased phosphorylation of UIMC1 protein CTD PMID:35688186 Uimc1 Rat cyclosporin A increases expression ISO Uimc1 (Mus musculus) 6480464 Cyclosporine results in increased expression of UIMC1 mRNA CTD PMID:19770486 Uimc1 Rat cyclosporin A increases expression ISO UIMC1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of UIMC1 mRNA CTD PMID:20106945|PMID:25562108|PMID:27989131 Uimc1 Rat DDE decreases expression ISO UIMC1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of UIMC1 mRNA CTD PMID:38568856 Uimc1 Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of UIMC1 mRNA CTD PMID:23640034 Uimc1 Rat diarsenic trioxide multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of UIMC1 mRNA CTD PMID:15894607 Uimc1 Rat Dibutyl phosphate affects expression ISO UIMC1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of UIMC1 mRNA CTD PMID:37042841 Uimc1 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of UIMC1 mRNA CTD PMID:21266533 Uimc1 Rat diquat decreases expression ISO Uimc1 (Mus musculus) 6480464 Diquat results in decreased expression of UIMC1 protein CTD PMID:36851058 Uimc1 Rat disodium selenite decreases expression ISO UIMC1 (Homo sapiens) 6480464 Sodium Selenite results in decreased expression of UIMC1 mRNA CTD PMID:24383545 Uimc1 Rat doxorubicin decreases expression ISO UIMC1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of UIMC1 mRNA CTD PMID:29803840 Uimc1 Rat doxorubicin increases phosphorylation ISO UIMC1 (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of UIMC1 protein CTD PMID:38367682 Uimc1 Rat enzyme inhibitor multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... CTD PMID:23301498 Uimc1 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of UIMC1 mRNA CTD PMID:24136188 Uimc1 Rat FR900359 affects phosphorylation ISO UIMC1 (Homo sapiens) 6480464 FR900359 affects the phosphorylation of UIMC1 protein CTD PMID:37730182 Uimc1 Rat gold atom increases expression ISO UIMC1 (Homo sapiens) 6480464 Gold results in increased expression of UIMC1 mRNA CTD PMID:29705079 Uimc1 Rat gold atom decreases expression ISO UIMC1 (Homo sapiens) 6480464 Gold results in decreased expression of UIMC1 mRNA CTD PMID:29705079 Uimc1 Rat gold(0) increases expression ISO UIMC1 (Homo sapiens) 6480464 Gold results in increased expression of UIMC1 mRNA CTD PMID:29705079 Uimc1 Rat gold(0) decreases expression ISO UIMC1 (Homo sapiens) 6480464 Gold results in decreased expression of UIMC1 mRNA CTD PMID:29705079 Uimc1 Rat isobutanol multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic more ... CTD PMID:29432896 Uimc1 Rat methapyrilene increases methylation ISO UIMC1 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of UIMC1 intron CTD PMID:30157460 Uimc1 Rat methyl methanesulfonate increases expression ISO UIMC1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of UIMC1 mRNA CTD PMID:23649840 Uimc1 Rat ozone multiple interactions ISO UIMC1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... CTD PMID:32699268|PMID:35430440 Uimc1 Rat paracetamol affects expression ISO Uimc1 (Mus musculus) 6480464 Acetaminophen affects the expression of UIMC1 mRNA CTD PMID:17562736 Uimc1 Rat PCB138 multiple interactions ISO Uimc1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uimc1 Rat phenobarbital affects expression ISO UIMC1 (Homo sapiens) 6480464 Phenobarbital affects the expression of UIMC1 mRNA CTD PMID:19159669 Uimc1 Rat sodium arsenite decreases expression ISO UIMC1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of UIMC1 mRNA CTD PMID:38568856 Uimc1 Rat tamoxifen affects expression ISO Uimc1 (Mus musculus) 6480464 Tamoxifen affects the expression of UIMC1 mRNA CTD PMID:17555576 Uimc1 Rat temozolomide increases expression ISO UIMC1 (Homo sapiens) 6480464 Temozolomide results in increased expression of UIMC1 mRNA CTD PMID:31758290 Uimc1 Rat triphenyl phosphate affects expression ISO UIMC1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of UIMC1 mRNA CTD PMID:37042841 Uimc1 Rat valproic acid decreases expression ISO UIMC1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of UIMC1 mRNA CTD PMID:23179753