Symbol:
Zbtb49
Name:
zinc finger and BTB domain containing 49
RGD ID:
1306733
Description:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Predicted to be involved in several processes, including negative regulation of cell population proliferation; regulation of cytokine production; and regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleus. Predicted to be active in nucleoplasm. Orthologous to human ZBTB49 (zinc finger and BTB domain containing 49); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC305428; Zfp509; zinc finger and BTB domain-containing protein 49; zinc finger protein 509; Znf509
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 14 76,802,988 - 76,835,573 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 14 76,802,495 - 76,824,718 (+) Ensembl GRCr8 mRatBN7.2 14 72,590,692 - 72,612,404 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 14 72,590,708 - 72,612,404 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 14 77,032,377 - 77,054,090 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 14 78,273,251 - 78,294,964 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 14 74,713,327 - 74,735,038 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 14 77,332,002 - 77,353,707 (+) NCBI Dahl_SR_JrHsd Lyon_Normotensive 14 75,960,751 - 75,982,456 (+) NCBI Lyon_Normotensive Lyon_Hypertensive 14 77,479,554 - 77,501,259 (+) NCBI Lyon_Hypertensive F344_StmMcwi 14 76,403,666 - 76,425,371 (+) NCBI F344_StmMcwi Rnor_6.0 14 77,322,014 - 77,343,736 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 14 77,322,012 - 77,343,764 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 14 77,303,883 - 77,325,598 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 14 77,873,462 - 77,895,156 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 14 71,541,223 - 71,562,888 (+) NCBI Celera RGSC_v3.1 14 77,875,524 - 77,897,199 (+) NCBI Cytogenetic Map 14 q21 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Zbtb49 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 1,2-dichloroethane decreases expression ISO Zbtb49 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of ZBTB49 mRNA CTD PMID:28960355 Zbtb49 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat aflatoxin B1 increases methylation ISO ZBTB49 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of ZBTB49 gene CTD PMID:27153756 Zbtb49 Rat amiodarone increases expression ISO ZBTB49 (Homo sapiens) 6480464 Amiodarone results in increased expression of ZBTB49 mRNA CTD PMID:19774075 Zbtb49 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat arsane affects methylation ISO ZBTB49 (Homo sapiens) 6480464 Arsenic affects the methylation of ZBTB49 gene CTD PMID:25304211 Zbtb49 Rat arsenic atom affects methylation ISO ZBTB49 (Homo sapiens) 6480464 Arsenic affects the methylation of ZBTB49 gene CTD PMID:25304211 Zbtb49 Rat arsenite(3-) multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to ZBTB49 mRNA] CTD PMID:32406909 Zbtb49 Rat benzo[a]pyrene increases methylation ISO ZBTB49 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ZBTB49 5' UTR CTD PMID:27901495 Zbtb49 Rat benzo[a]pyrene decreases methylation ISO Zbtb49 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of ZBTB49 exon; Benzo(a)pyrene results in decreased methylation of ZBTB49 more ... CTD PMID:27901495 Zbtb49 Rat bis(2-ethylhexyl) phthalate increases expression ISO Zbtb49 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of ZBTB49 mRNA CTD PMID:34319233 Zbtb49 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ZBTB49 mRNA CTD PMID:25181051 Zbtb49 Rat bisphenol A affects splicing ISO Zbtb49 (Mus musculus) 6480464 bisphenol A affects the splicing of ZBTB49 mRNA CTD PMID:37894381 Zbtb49 Rat bisphenol F decreases expression ISO Zbtb49 (Mus musculus) 6480464 bisphenol F results in decreased expression of ZBTB49 mRNA CTD PMID:38685157 Zbtb49 Rat C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of ZBTB49 mRNA CTD PMID:19167457 Zbtb49 Rat cadmium atom multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ZBTB49 more ... CTD PMID:35301059 Zbtb49 Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZBTB49 more ... CTD PMID:39012411 Zbtb49 Rat cadmium dichloride multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ZBTB49 more ... CTD PMID:35301059 Zbtb49 Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZBTB49 more ... CTD PMID:39012411 Zbtb49 Rat caffeine decreases phosphorylation ISO ZBTB49 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of ZBTB49 protein CTD PMID:35688186 Zbtb49 Rat CGP 52608 multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ZBTB49 gene] CTD PMID:28238834 Zbtb49 Rat cyclosporin A increases expression ISO ZBTB49 (Homo sapiens) 6480464 Cyclosporine results in increased expression of ZBTB49 mRNA CTD PMID:20106945 Zbtb49 Rat fipronil decreases expression EXP 6480464 fipronil results in decreased expression of ZBTB49 mRNA CTD PMID:34044035 Zbtb49 Rat folic acid increases expression ISO Zbtb49 (Mus musculus) 6480464 Folic Acid results in increased expression of ZBTB49 mRNA CTD PMID:25629700 Zbtb49 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat paracetamol affects expression ISO Zbtb49 (Mus musculus) 6480464 Acetaminophen affects the expression of ZBTB49 mRNA CTD PMID:17562736 Zbtb49 Rat PCB138 multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of ZBTB49 mRNA CTD PMID:19281266 Zbtb49 Rat sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat sunitinib increases expression ISO ZBTB49 (Homo sapiens) 6480464 Sunitinib results in increased expression of ZBTB49 mRNA CTD PMID:31533062 Zbtb49 Rat titanium dioxide decreases methylation ISO Zbtb49 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of ZBTB49 gene CTD PMID:35295148 Zbtb49 Rat triphenyl phosphate affects expression ISO ZBTB49 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ZBTB49 mRNA CTD PMID:37042841 Zbtb49 Rat triptonide increases expression ISO Zbtb49 (Mus musculus) 6480464 triptonide results in increased expression of ZBTB49 mRNA CTD PMID:33045310 Zbtb49 Rat trovafloxacin increases expression ISO Zbtb49 (Mus musculus) 6480464 trovafloxacin results in increased expression of ZBTB49 mRNA CTD PMID:35537566 Zbtb49 Rat valproic acid increases methylation ISO ZBTB49 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ZBTB49 gene CTD PMID:29154799