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Gene: Gpr15 (G protein-coupled receptor 15) Rattus norvegicus

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Symbol:

Gpr15

Name:

G protein-coupled receptor 15

RGD ID:

1306639

Description:

Predicted to enable G protein-coupled receptor activity; coreceptor activity; and virus receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; angiogenesis; and symbiont entry into host cell. Predicted to act upstream of or within T cell migration. Predicted to be located in endosome. Predicted to be active in plasma membrane. Orthologous to human GPR15 (G protein-coupled receptor 15); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; alpha-Zearalanol; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

G-protein coupled receptor 15; LOC288181

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR15 (G protein-coupled receptor 15)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Gpr15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gpr15 (G protein-coupled receptor 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GPR15 (G protein-coupled receptor 15)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpr15 (G protein-coupled receptor 15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	npr-33	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Caenorhabditis elegans (roundworm):	npr-15	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	55,367,496 - 55,368,842 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	55,358,614 - 55,374,150 (+)	Ensembl				GRCr8
mRatBN7.2	11	41,898,300 - 41,899,646 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	41,898,356 - 41,900,441 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	50,645,971 - 50,647,317 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	43,307,532 - 43,308,878 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	42,436,174 - 42,437,520 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	57,272,302 - 57,273,648 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	55,498,741 - 55,500,087 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	56,406,927 - 56,408,273 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	55,177,152 - 55,178,498 (+)	NCBI		F344_StmMcwi
Rnor_6.0	11	43,992,739 - 44,004,189 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	44,001,579 - 44,003,664 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	47,191,271 - 47,193,356 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	42,709,928 - 42,712,013 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	41,697,724 - 41,699,809 (+)	NCBI		Celera
RGSC_v3.1	11	42,767,516 - 42,768,599 (+)	NCBI
Cytogenetic Map	11	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

3,3',4,4',5-pentachlorobiphenyl (EXP)

alpha-Zearalanol (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

C60 fullerene (EXP)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

diuron (ISO)

gentamycin (EXP)

methcathinone (ISO)

pirinixic acid (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IBA,ISO)

G protein-coupled receptor signaling pathway (IBA,IEA,ISO)

signal transduction (IEA)

symbiont entry into host cell (ISO)

T cell migration (ISO)

Cellular Component

cytoplasm (ISO)

endosome (ISO)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

Molecular Function

coreceptor activity (ISO)

G protein-coupled receptor activity (IBA,IEA,ISO)

protein binding (ISO)

virus receptor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11696454	PMID:15650194	PMID:23661644	PMID:28615320	PMID:28900043	PMID:28936214

Genomics

Comparative Map Data

Gpr15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	55,367,496 - 55,368,842 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	55,358,614 - 55,374,150 (+)	Ensembl				GRCr8
mRatBN7.2	11	41,898,300 - 41,899,646 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	41,898,356 - 41,900,441 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	50,645,971 - 50,647,317 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	43,307,532 - 43,308,878 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	42,436,174 - 42,437,520 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	57,272,302 - 57,273,648 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	55,498,741 - 55,500,087 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	56,406,927 - 56,408,273 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	55,177,152 - 55,178,498 (+)	NCBI		F344_StmMcwi
Rnor_6.0	11	43,992,739 - 44,004,189 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	44,001,579 - 44,003,664 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	47,191,271 - 47,193,356 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	42,709,928 - 42,712,013 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	41,697,724 - 41,699,809 (+)	NCBI		Celera
RGSC_v3.1	11	42,767,516 - 42,768,599 (+)	NCBI
Cytogenetic Map	11	q12	NCBI

GPR15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	98,531,978 - 98,534,681 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	98,531,978 - 98,534,681 (+)	Ensembl			hg38	GRCh38
GRCh37	3	98,250,822 - 98,253,525 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	99,733,568 - 99,734,650 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	99,733,567 - 99,734,650	NCBI
Celera	3	96,642,535 - 96,643,617 (+)	NCBI		Celera
Cytogenetic Map	3	q11.2	NCBI
HuRef	3	95,622,878 - 95,624,129 (+)	NCBI		HuRef
CHM1_1	3	98,213,900 - 98,215,151 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	101,235,662 - 101,238,365 (+)	NCBI		T2T-CHM13v2.0

Gpr15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	58,537,006 - 58,539,235 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	58,537,796 - 58,539,433 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	58,716,643 - 58,718,872 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	58,717,433 - 58,719,070 (-)	Ensembl			mm10	GRCm38
MGSCv37	16	58,717,548 - 58,718,837 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	58,659,978 - 58,661,613 (-)	NCBI		MGSCv36	mm8
Celera	16	59,008,102 - 59,009,391 (-)	NCBI		Celera
Cytogenetic Map	16	C1.2	NCBI
cM Map	16	34.83	NCBI

Gpr15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	115,513 - 119,710 (+)	Ensembl
ChiLan1.0	NW_004955427	115,513 - 137,557 (+)	NCBI	ChiLan1.0	ChiLan1.0

GPR15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	96,468,265 - 96,470,966 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	96,473,048 - 96,475,749 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	95,627,750 - 95,630,518 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	102,311,074 - 102,313,840 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	102,311,203 - 102,312,285 (+)	Ensembl			panPan2	panpan1.1

GPR15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	5,368,509 - 5,380,024 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	5,396,083 - 5,397,165 (+)	Ensembl			canFam3	CanFam3.1
CanFam3.1 Ensembl	33	5,396,083 - 5,397,165 (+)	NCBI			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	5,519,620 - 5,548,538 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	5,507,924 - 5,538,951 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	5,535,357 - 5,537,206 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	5,385,504 - 5,414,699 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	5,448,924 - 5,478,064 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	5,725,631 - 5,754,875 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gpr15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	151,562,917 - 151,564,586 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936630	4,461,085 - 4,462,167 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936630	4,459,213 - 4,462,285 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	160,386,728 - 160,389,384 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	160,386,727 - 160,390,965 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	170,557,577 - 170,579,565 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	82,314,259 - 82,317,204 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	82,314,491 - 82,315,573 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	84,238,542 - 84,241,336 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624789	11,401,221 - 11,402,303 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624789	11,401,196 - 11,402,337 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gpr15
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	42,685,157 - 42,686,909 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gpr15
79 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	335
Count of miRNA genes:	188
Interacting mature miRNAs:	217
Transcripts:	ENSRNOT00000002258
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	22524746	82951192	Rat
1598841	Memor7	Memory QTL 7			exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	11	33306008	78306008	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	46443168	91443168	Rat
1598811	Bp291	Blood pressure QTL 291	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	33306008	78306008	Rat
11528648	Bss118	Bone structure and strength QTL 118	6.658	2e-07	femur strength trait (VT:0010010)	femur ultimate displacement (CMO:0002719)	11	54107987	56845449	Rat
634339	Niddm50	Non-insulin dependent diabetes mellitus QTL 50	3.32		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	10806125	55806125	Rat
634341	Bw121	Body weight QTL 121	3.56		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight (CMO:0000088)	11	35323199	55805892	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	32943067	89836615	Rat
724517	Uae18	Urinary albumin excretion QTL 18	3.7		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	29958996	57754989	Rat
2290451	Scl58	Serum cholesterol level QTL 58	3.48		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	11	26318031	55806125	Rat
1300130	Rf20	Renal function QTL 20	4.44		kidney glomerulus integrity trait (VT:0010546)	kidney glomerulus diameter (CMO:0001166)	11	31915469	76915469	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	36428416	81428416	Rat
1600394	Edcs1	Endometrial carcinoma susceptibility QTL1	2.9	0.04	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	11	12823152	57823152	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	34618760	79618760	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	54415391	96071021	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	36749459	81749459	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	36749459	81749459	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	51071021	96071021	Rat
631510	Spl2	Serum phospholipid level QTL 2	4.1		blood phospholipid amount (VT:0006084)	serum phospholipid level (CMO:0001171)	11	27556685	72556685	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	10	19	61	59	58	27	89	27	6	222	136	6	36	39	49	31	1	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000002258 ⟹ ENSRNOP00000002258

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	55,359,187 - 55,369,524 (+)	Ensembl
mRatBN7.2 Ensembl	11	41,898,356 - 41,900,441 (+)	Ensembl
Rnor_6.0 Ensembl	11	44,001,579 - 44,003,664 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000169932 ⟹ ENSRNOP00000108572

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	55,358,614 - 55,374,150 (+)	Ensembl

RefSeq Acc Id:

NM_001105890 ⟹ NP_001099360

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	55,367,496 - 55,368,842 (+)	NCBI
mRatBN7.2	11	41,898,300 - 41,899,646 (+)	NCBI
Dahl_SR_JrHsd	11	57,272,302 - 57,273,648 (+)	NCBI
Lyon_Normotensive	11	55,498,741 - 55,500,087 (+)	NCBI
Lyon_Hypertensive	11	56,406,927 - 56,408,273 (+)	NCBI
F344_StmMcwi	11	55,177,152 - 55,178,498 (+)	NCBI
Rnor_6.0	11	44,001,579 - 44,003,664 (+)	NCBI
Rnor_5.0	11	47,191,271 - 47,193,356 (+)	NCBI
RGSC_v3.4	11	42,709,928 - 42,712,013 (+)	RGD
Celera	11	41,697,724 - 41,699,809 (+)	RGD

Sequence:

show sequence

ATGGAACCAGCAACAACCCTGTTTTATCTGGATTACTATGATGCTACGAGCCCGGATCCTCGTA
TCATGGAGACTCCCTCCCACACTTCCTACACATCTGTCTTCCTCCCTGTCTTTTACACAGCTGT
GTTCCTGACTGGAGTGTTGGGGAATTTCATCCTCATGGTCACTCTGCATTTCAAACACCGCAAC
CGAAGATTGATCGATATCTTTATCATCAACCTGGCTGCCTCGGACTTCATTTTCCTTGTCACAC
TGCCACTTTGGGTAGATAAGGAAGCCTCTCTGGGACTGTGGAGGACTGGCTCTCTCCTGTGCAA
AGGCAGCTCCTATACGATCTCAGTGAACATGCACTGTAATGTCTTCTTGCTCACGTGTATGAGC
ATGGACCGCTACCTGGCCATCATGCGCCCAACCTTAGCCAGGAGATTAAGAAGGAGAAGCTGTG
CATACGCGGTGTGTGCTGTCATCTGGATCATCTCATGCCTCTTAGGATTACCCACTCTTCTGTC
CAGAGGGCTCACTCACATTGAAGGCAAGCCGTACTGTGCAGAGAAGAAACCCACGTCATTAAAA
CTGATGTGGGGGCTGGTAGCCTTGATTGCCACCTTTTTTGTCCCCCTCCTGAGCATTGTGTCCA
GCTACTGTTGCATCACAAGGAGGCTGTGTGCTCATTACCAGCAGTCGGGAAAGCATAACAAGAA
ATTGAGGAAGTCCATAAAGATCATCGTTATTGTGGTGGCGGCCTTCACCATCTCCTGGGTGCCC
TTTAACACTGTCAAGCTCCTAGCCATTGTTTCAGGATTGCAACCTGAAAGCCAGTTTCCCTCCG
AGTCTCTTCAGCAGGCCATGAAGGTGACTGGGTCCTTGGCATTTGCCAACAGCTGCGTCAACCC
TCTCCTTTACTATATCTTTGACAGCTATATCCGCCGGGCCATTGTACGCAGTCTGTGCCCTTGT
CTGAAGATCCACAACATTGGGAGTAGCACTGAGACATTAGACAGTCACCTCACCAAGGCTCTTG
CCAACTTCATTCACTCAGAAGATTTTGTCAAGCGGAGGAAGAGGTCTGTGTCACTCTGAAAGGA
GCTGTGACATTTCAAGTTCTGTTGGCACTCTTGGGAAGCTGGGTTTTGTCAGCAGCAGAGAAAG
AGAAAAGCATTAAAGATAAAATTCATATTGATTCATAAATCCAAGCAAGTGTCGGCTTTTTTTT
AAAGCCTCCCTGAAGAGCTCCTGTACTGTGGATGTAATTAGGACATATGCAGTATTTTCAAACC
TTGGAGGTCTTACTTGGGAATCAAGCCAACCAGACAAAATACAAACTCCATTGTCCCTGAACTC
AAAGTCCGTTTTCTTCATGGGTGCCAACGCAACTTCAGGTCTCTCAAGACCACCCACTGTTCAT
GCTGGGCTGCGTTTGAAAGAGATGCCTTCATCTGTCATAGCTTTGGACTAGAAAAAAAGAAAGA
AAGAAAGAAAGGAAGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA
GAGAGAAAGAGAAAGAAAGAGAAAAAGAGAAAGAACCCCAAGAGGAATAAGCCACTATGCATTG
TGTTTGTGAATTAAGAAATGACTTCATCACCTGATCTGAAATGTGTTAGCAAAGTACTCATTGC
CTAAGGTTTGACCTTTGCCTTGTGAGAAACATTAGTAACCATCCAGCTTATTATAATATGCCAC
GGTAACTGCTTTTTAAAAAGATGTTAATACGCTGTTTGTTTTCATTGCCTTTATAAATTAGAAT
CTGACTTTGTTGTAATTACATGTTCTGAATTACCTATCATCTAGTTATCAAATGAAAATGTTAC
TACTAATGTAATTGGAGCTTGGAGGCTTGGGCCCACCCCCATGCAGATTATCACTTGAGGTTCT
AATTAAAATGTTACTGTGC

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Protein Sequences


Protein RefSeqs	NP_001099360	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM11015	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002258
	ENSRNOP00000002258.4
	ENSRNOP00000108572.1

RefSeq Acc Id:

NP_001099360 ⟸ NM_001105890

- UniProtKB:

D4AA67 (UniProtKB/TrEMBL), A6IQL2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEPATTLFYLDYYDATSPDPRIMETPSHTSYTSVFLPVFYTAVFLTGVLGNFILMVTLHFKHRN
RRLIDIFIINLAASDFIFLVTLPLWVDKEASLGLWRTGSLLCKGSSYTISVNMHCNVFLLTCMS
MDRYLAIMRPTLARRLRRRSCAYAVCAVIWIISCLLGLPTLLSRGLTHIEGKPYCAEKKPTSLK
LMWGLVALIATFFVPLLSIVSSYCCITRRLCAHYQQSGKHNKKLRKSIKIIVIVVAAFTISWVP
FNTVKLLAIVSGLQPESQFPSESLQQAMKVTGSLAFANSCVNPLLYYIFDSYIRRAIVRSLCPC
LKIHNIGSSTETLDSHLTKALANFIHSEDFVKRRKRSVSL

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Ensembl Acc Id:

ENSRNOP00000002258 ⟸ ENSRNOT00000002258

Ensembl Acc Id:

ENSRNOP00000108572 ⟸ ENSRNOT00000169932

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AA67-F1-model_v2	AlphaFold	D4AA67	1-360	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306639	AgrOrtholog
BioCyc Gene	G2FUF-21571	BioCyc
Ensembl Genes	ENSRNOG00000039680	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002258	ENTREZGENE
	ENSRNOT00000002258.7	UniProtKB/TrEMBL
	ENSRNOT00000169932.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	7TM_GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR1	UniProtKB/TrEMBL
	GPCR_Rhodpsn_supfam	UniProtKB/TrEMBL
KEGG Report	rno:288181	UniProtKB/TrEMBL
NCBI Gene	288181	ENTREZGENE
PANTHER	CELL ADHESION MOLECULE	UniProtKB/TrEMBL
	G PROTEIN-COUPLED RECEPTOR 25	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PhenoGen	Gpr15	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000039680	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A6IQL2	ENTREZGENE, UniProtKB/TrEMBL
	D4AA67	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Gpr15	G protein-coupled receptor 15	Gpr15_predicted	G protein-coupled receptor 15 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Gpr15_predicted	G protein-coupled receptor 15 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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