Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Egflam | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Egflam (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of EGFLAM mRNA | CTD | PMID:22206623 | Egflam | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Egflam (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of EGFLAM mRNA | CTD | PMID:21570461 | Egflam | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EGFLAM mRNA | CTD | PMID:33387578 | Egflam | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of EGFLAM mRNA | CTD | PMID:34747641 | Egflam | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EGFLAM mRNA | CTD | PMID:32119087 | Egflam | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Egflam (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of EGFLAM mRNA | CTD | PMID:25172293 | Egflam | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Egflam | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Egflam (Mus musculus) | 6480464 | bisphenol S results in increased expression of EGFLAM mRNA | CTD | PMID:30951980 | Egflam | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Egflam (Mus musculus) | 6480464 | bisphenol S affects the methylation of EGFLAM gene | CTD | PMID:31683443 | Egflam | Rat | aflatoxin B1 | affects methylation | ISO | EGFLAM (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of EGFLAM intron | CTD | PMID:30157460 | Egflam | Rat | all-trans-retinoic acid | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of EGFLAM mRNA | CTD | PMID:23724009 | Egflam | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of EGFLAM mRNA | CTD | PMID:30047161 | Egflam | Rat | arsane | affects methylation | ISO | EGFLAM (Homo sapiens) | 6480464 | Arsenic affects the methylation of EGFLAM gene | CTD | PMID:25304211 | Egflam | Rat | arsenic atom | affects methylation | ISO | EGFLAM (Homo sapiens) | 6480464 | Arsenic affects the methylation of EGFLAM gene | CTD | PMID:25304211 | Egflam | Rat | arsenite(3-) | increases methylation | ISO | EGFLAM (Homo sapiens) | 6480464 | arsenite results in increased methylation of EGFLAM promoter | CTD | PMID:23974009 | Egflam | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of EGFLAM gene | CTD | PMID:35440735 | Egflam | Rat | benzo[a]pyrene | affects methylation | ISO | EGFLAM (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of EGFLAM intron; Benzo(a)pyrene affects the methylation of EGFLAM promoter | CTD | PMID:27901495|PMID:30157460 | Egflam | Rat | benzo[a]pyrene | increases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of EGFLAM mRNA | CTD | PMID:38036013 | Egflam | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of EGFLAM more ... | CTD | PMID:23359474 | Egflam | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of EGFLAM more ... | CTD | PMID:33872906 | Egflam | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of EGFLAM more ... | CTD | PMID:23359474 | Egflam | Rat | bisphenol A | decreases methylation | ISO | EGFLAM (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of EGFLAM gene | CTD | PMID:31601247 | Egflam | Rat | bisphenol A | increases expression | ISO | Egflam (Mus musculus) | 6480464 | bisphenol A results in increased expression of EGFLAM mRNA | CTD | PMID:30951980 | Egflam | Rat | bisphenol A | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Egflam | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of EGFLAM mRNA | CTD | PMID:29097150 | Egflam | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of EGFLAM mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998|PMID:38750585 | Egflam | Rat | bisphenol F | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Egflam | Rat | bisphenol F | increases expression | ISO | Egflam (Mus musculus) | 6480464 | bisphenol F results in increased expression of EGFLAM mRNA | CTD | PMID:30951980 | Egflam | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of EGFLAM mRNA | CTD | PMID:33453195 | Egflam | Rat | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of EGFLAM mRNA | CTD | PMID:30556269 | Egflam | Rat | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of EGFLAM mRNA | CTD | PMID:30556269 | Egflam | Rat | cyclosporin A | decreases methylation | ISO | EGFLAM (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of EGFLAM promoter | CTD | PMID:27989131 | Egflam | Rat | cytarabine | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of EGFLAM mRNA | CTD | PMID:21198554 | Egflam | Rat | DDT | increases expression | EXP | | 6480464 | DDT results in increased expression of EGFLAM mRNA | CTD | PMID:30207508 | Egflam | Rat | dexamethasone | increases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of EGFLAM mRNA | CTD | PMID:25047013 | Egflam | Rat | dexamethasone | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Egflam | Rat | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of EGFLAM more ... | CTD | PMID:23359474 | Egflam | Rat | dioxygen | multiple interactions | ISO | Egflam (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of EGFLAM mRNA | CTD | PMID:30529165 | Egflam | Rat | diquat | decreases expression | ISO | Egflam (Mus musculus) | 6480464 | Diquat results in decreased expression of EGFLAM mRNA | CTD | PMID:36851058 | Egflam | Rat | dorsomorphin | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Egflam | Rat | doxorubicin | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of EGFLAM mRNA | CTD | PMID:29803840 | Egflam | Rat | doxorubicin | decreases expression | ISO | Egflam (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of EGFLAM mRNA | CTD | PMID:39631538 | Egflam | Rat | entinostat | increases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | entinostat results in increased expression of EGFLAM mRNA | CTD | PMID:27188386 | Egflam | Rat | ethylparaben | increases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of EGFLAM mRNA | CTD | PMID:37690743 | Egflam | Rat | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of EGFLAM mRNA | CTD | PMID:22129741 | Egflam | Rat | indometacin | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Egflam | Rat | lead(0) | affects expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Lead affects the expression of EGFLAM mRNA | CTD | PMID:28903495 | Egflam | Rat | methamphetamine | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA | CTD | PMID:19564919 | Egflam | Rat | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of EGFLAM mRNA | CTD | PMID:19564919 | Egflam | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of EGFLAM more ... | CTD | PMID:33872906 | Egflam | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of EGFLAM mRNA | CTD | PMID:22129741 | Egflam | Rat | okadaic acid | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of EGFLAM mRNA | CTD | PMID:38832940 | Egflam | Rat | ozone | multiple interactions | ISO | Egflam (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Egflam | Rat | paracetamol | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of EGFLAM mRNA | CTD | PMID:26690555 | Egflam | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of EGFLAM mRNA | CTD | PMID:32680482 | Egflam | Rat | pioglitazone | multiple interactions | ISO | Egflam (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGFLAM mRNA | CTD | PMID:27935865 | Egflam | Rat | rotenone | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Rotenone results in decreased expression of EGFLAM mRNA | CTD | PMID:29955902 | Egflam | Rat | SB 431542 | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Egflam | Rat | SCH 23390 | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA | CTD | PMID:19564919 | Egflam | Rat | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of EGFLAM mRNA | CTD | PMID:22431001 | Egflam | Rat | sodium arsenite | increases expression | ISO | Egflam (Mus musculus) | 6480464 | sodium arsenite results in increased expression of EGFLAM mRNA | CTD | PMID:37682722 | Egflam | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of EGFLAM mRNA | CTD | PMID:19281266 | Egflam | Rat | tebuconazole | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | tebuconazole results in decreased expression of EGFLAM mRNA | CTD | PMID:30458266 | Egflam | Rat | testosterone | decreases expression | ISO | Egflam (Mus musculus) | 6480464 | Testosterone results in decreased expression of EGFLAM mRNA | CTD | PMID:20403060 | Egflam | Rat | thiram | decreases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Thiram results in decreased expression of EGFLAM mRNA | CTD | PMID:38568856 | Egflam | Rat | toluene | increases expression | EXP | | 6480464 | Toluene results in increased expression of EGFLAM mRNA | CTD | PMID:22967744 | Egflam | Rat | triadimefon | increases expression | EXP | | 6480464 | triadimefon results in increased expression of EGFLAM mRNA | CTD | PMID:30047161 | Egflam | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of EGFLAM mRNA | CTD | PMID:33387578 | Egflam | Rat | trichostatin A | increases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | trichostatin A results in increased expression of EGFLAM mRNA | CTD | PMID:24935251 | Egflam | Rat | trimellitic anhydride | decreases expression | ISO | Egflam (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of EGFLAM mRNA | CTD | PMID:19042947 | Egflam | Rat | valproic acid | affects expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Valproic Acid affects the expression of EGFLAM mRNA | CTD | PMID:25979313 | Egflam | Rat | valproic acid | increases expression | ISO | Egflam (Mus musculus) | 6480464 | Valproic Acid results in increased expression of EGFLAM mRNA | CTD | PMID:24896083 | Egflam | Rat | valproic acid | increases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of EGFLAM mRNA | CTD | PMID:23179753|PMID:26272509 | Egflam | Rat | valproic acid | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Egflam | Rat | vorinostat | multiple interactions | ISO | EGFLAM (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Egflam | Rat | vorinostat | increases expression | ISO | EGFLAM (Homo sapiens) | 6480464 | vorinostat results in increased 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