Agtpbp1 (ATP/GTP binding carboxypeptidase 1) - Rat Genome Database

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Pathways
Gene: Agtpbp1 (ATP/GTP binding carboxypeptidase 1) Rattus norvegicus
Analyze
Symbol: Agtpbp1
Name: ATP/GTP binding carboxypeptidase 1
RGD ID: 1306307
Description: Predicted to enable metallocarboxypeptidase activity and tubulin binding activity. Predicted to be involved in eye photoreceptor cell differentiation; mitochondrion organization; and olfactory bulb development. Predicted to act upstream of or within several processes, including adult walking behavior; axonal transport of mitochondrion; and central nervous system neuron differentiation. Predicted to be located in cytosol and mitochondrion. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Orthologous to human AGTPBP1 (ATP/GTP binding carboxypeptidase 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP/GTP binding protein 1; cytosolic carboxypeptidase 1; LOC290986
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8175,092,108 - 5,244,414 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl175,126,146 - 5,244,420 (+)EnsemblGRCr8
mRatBN7.2175,120,540 - 5,238,874 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl175,120,609 - 5,238,869 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx175,153,873 - 5,264,101 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0176,694,971 - 6,799,992 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0175,150,307 - 5,260,529 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0175,510,009 - 5,614,416 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl175,511,385 - 5,614,435 (+)Ensemblrn6Rnor6.0
Rnor_5.0177,722,385 - 7,837,764 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41711,040,339 - 11,155,923 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera175,254,268 - 5,358,824 (+)NCBICelera
RGSC_v3.11711,063,063 - 11,155,645 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2-methoxyethanol  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
fenvalerate  (EXP)
fipronil  (EXP)
folic acid  (ISO)
genistein  (ISO)
glycidol  (EXP)
L-methionine  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
methylphenidate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
naled  (ISO)
nickel sulfate  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IEA)
axon cytoplasm  (IEA)
cytoplasm  (IBA,ISO)
cytosol  (IEA,ISO)
microtubule cytoskeleton  (IBA)
mitochondrion  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:23085998   PMID:30420557  


Genomics

Comparative Map Data
Agtpbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8175,092,108 - 5,244,414 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl175,126,146 - 5,244,420 (+)EnsemblGRCr8
mRatBN7.2175,120,540 - 5,238,874 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl175,120,609 - 5,238,869 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx175,153,873 - 5,264,101 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0176,694,971 - 6,799,992 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0175,150,307 - 5,260,529 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0175,510,009 - 5,614,416 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl175,511,385 - 5,614,435 (+)Ensemblrn6Rnor6.0
Rnor_5.0177,722,385 - 7,837,764 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41711,040,339 - 11,155,923 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera175,254,268 - 5,358,824 (+)NCBICelera
RGSC_v3.11711,063,063 - 11,155,645 (+)NCBI
Cytogenetic Map17p14NCBI
AGTPBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38985,546,539 - 85,805,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl985,546,539 - 85,742,144 (-)Ensemblhg38GRCh38
GRCh37988,161,454 - 88,356,944 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36987,351,275 - 87,546,709 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34985,391,008 - 85,586,443NCBI
Celera958,731,693 - 58,927,167 (-)NCBICelera
Cytogenetic Map9q21.33NCBI
HuRef957,985,670 - 58,181,366 (-)NCBIHuRef
CHM1_1988,308,168 - 88,503,654 (-)NCBICHM1_1
T2T-CHM13v2.0997,697,026 - 97,955,976 (-)NCBIT2T-CHM13v2.0
Agtpbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391359,597,348 - 59,705,184 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1359,593,556 - 59,733,041 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381359,449,534 - 59,557,370 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1359,445,742 - 59,585,227 (-)Ensemblmm10GRCm38
MGSCv371359,550,896 - 59,658,680 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361359,459,518 - 59,566,909 (-)NCBIMGSCv36mm8
Celera1360,505,890 - 60,600,548 (-)NCBICelera
Cytogenetic Map13B2NCBI
cM Map1337.0NCBI
Agtpbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554321,628,913 - 1,818,454 (+)Ensembl
ChiLan1.0NW_0049554321,628,966 - 1,816,373 (+)NCBIChiLan1.0ChiLan1.0
AGTPBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21184,681,031 - 84,876,912 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1984,686,971 - 84,882,852 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0939,161,182 - 39,357,043 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1984,871,571 - 85,049,056 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl984,871,450 - 85,037,897 (-)EnsemblpanPan2panpan1.1
AGTPBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1173,853,491 - 74,030,075 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl173,887,934 - 74,107,312 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha174,616,116 - 74,795,461 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0174,158,469 - 74,338,565 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl174,158,416 - 74,336,496 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1173,967,595 - 74,147,352 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0173,736,759 - 73,916,152 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0174,439,370 - 74,619,422 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Agtpbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947120,497,104 - 120,673,188 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366801,065,937 - 1,240,875 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366801,065,375 - 1,240,909 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGTPBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1029,440,145 - 29,590,454 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11029,440,150 - 29,590,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21033,515,965 - 33,666,698 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AGTPBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11296,342,193 - 96,534,981 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1296,342,759 - 96,534,800 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603884,694,874 - 84,887,676 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agtpbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248099,119,951 - 9,339,604 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248099,119,412 - 9,321,226 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Agtpbp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11478,580,921 - 78,699,019 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Agtpbp1
1082 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:40
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000025381
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
RH129402  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2175,238,648 - 5,238,838 (+)MAPPERmRatBN7.2
Rnor_6.0175,614,196 - 5,614,385NCBIRnor6.0
Rnor_5.0177,837,542 - 7,837,731UniSTSRnor5.0
RGSC_v3.41711,155,703 - 11,155,892UniSTSRGSC3.4
Celera175,358,604 - 5,358,793UniSTS
RH 3.4 Map1773.7UniSTS
Cytogenetic Map17p14UniSTS
RH129762  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2175,238,637 - 5,238,838 (+)MAPPERmRatBN7.2
Rnor_6.0175,614,185 - 5,614,385NCBIRnor6.0
Rnor_5.0177,837,531 - 7,837,731UniSTSRnor5.0
RGSC_v3.41711,155,692 - 11,155,892UniSTSRGSC3.4
Celera175,358,593 - 5,358,793UniSTS
RH 3.4 Map1773.7UniSTS
Cytogenetic Map17p14UniSTS
RH143444  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2175,185,545 - 5,185,679 (+)MAPPERmRatBN7.2
Rnor_6.0175,563,940 - 5,564,073NCBIRnor6.0
Rnor_5.0177,787,457 - 7,787,590UniSTSRnor5.0
RGSC_v3.41711,102,557 - 11,102,690UniSTSRGSC3.4
Celera175,305,354 - 5,305,487UniSTS
RH 3.4 Map1773.7UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC158657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000025381   ⟹   ENSRNOP00000025382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,126,146 - 5,244,415 (+)Ensembl
mRatBN7.2 Ensembl175,133,698 - 5,238,869 (+)Ensembl
Rnor_6.0 Ensembl175,511,385 - 5,614,416 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091370   ⟹   ENSRNOP00000071198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,126,151 - 5,244,076 (+)Ensembl
mRatBN7.2 Ensembl175,120,609 - 5,233,767 (+)Ensembl
Rnor_6.0 Ensembl175,513,930 - 5,614,435 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146723   ⟹   ENSRNOP00000110575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,126,427 - 5,239,312 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000147265   ⟹   ENSRNOP00000098927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,126,427 - 5,244,418 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166040   ⟹   ENSRNOP00000101042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,126,427 - 5,244,420 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000168062   ⟹   ENSRNOP00000099619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,126,146 - 5,244,415 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000170055   ⟹   ENSRNOP00000109333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,126,183 - 5,244,074 (+)Ensembl
RefSeq Acc Id: NM_001106100   ⟹   NP_001099570
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,139,253 - 5,244,414 (+)NCBI
mRatBN7.2175,133,698 - 5,238,869 (+)NCBI
Rnor_6.0175,511,385 - 5,614,416 (+)NCBI
Rnor_5.0177,722,385 - 7,837,764 (+)NCBI
RGSC_v3.41711,040,339 - 11,155,923 (+)RGD
Celera175,254,268 - 5,358,824 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095446   ⟹   XP_038951374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,244,414 (+)NCBI
mRatBN7.2175,120,542 - 5,238,535 (+)NCBI
RefSeq Acc Id: XM_039095447   ⟹   XP_038951375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,548 - 5,244,414 (+)NCBI
mRatBN7.2175,120,993 - 5,238,535 (+)NCBI
RefSeq Acc Id: XM_039095448   ⟹   XP_038951376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,342 - 5,244,414 (+)NCBI
mRatBN7.2175,120,779 - 5,238,535 (+)NCBI
RefSeq Acc Id: XM_039095449   ⟹   XP_038951377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,134,263 - 5,244,414 (+)NCBI
mRatBN7.2175,134,419 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095450   ⟹   XP_038951378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,662 - 5,244,414 (+)NCBI
mRatBN7.2175,120,991 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095451   ⟹   XP_038951379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,244,414 (+)NCBI
mRatBN7.2175,120,542 - 5,238,871 (+)NCBI
RefSeq Acc Id: XM_039095452   ⟹   XP_038951380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,548 - 5,244,414 (+)NCBI
mRatBN7.2175,120,993 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095454   ⟹   XP_038951382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,094 - 5,244,414 (+)NCBI
mRatBN7.2175,120,540 - 5,238,871 (+)NCBI
RefSeq Acc Id: XM_039095455   ⟹   XP_038951383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,561 - 5,244,414 (+)NCBI
mRatBN7.2175,120,991 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095456   ⟹   XP_038951384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,285 - 5,244,414 (+)NCBI
mRatBN7.2175,120,735 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095457   ⟹   XP_038951385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,244,414 (+)NCBI
mRatBN7.2175,120,632 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095460   ⟹   XP_038951388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,244,414 (+)NCBI
mRatBN7.2175,120,632 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095461   ⟹   XP_038951389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,240,524 (+)NCBI
mRatBN7.2175,120,632 - 5,235,829 (+)NCBI
RefSeq Acc Id: XM_039095462   ⟹   XP_038951390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,092 - 5,244,414 (+)NCBI
mRatBN7.2175,120,550 - 5,238,871 (+)NCBI
RefSeq Acc Id: XM_039095463   ⟹   XP_038951391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,243 - 5,244,414 (+)NCBI
mRatBN7.2175,121,004 - 5,238,871 (+)NCBI
RefSeq Acc Id: XM_039095464   ⟹   XP_038951392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,244,414 (+)NCBI
mRatBN7.2175,120,632 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095465   ⟹   XP_038951393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,244,414 (+)NCBI
mRatBN7.2175,120,632 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_039095466   ⟹   XP_038951394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,164,589 - 5,244,414 (+)NCBI
mRatBN7.2175,159,034 - 5,238,874 (+)NCBI
RefSeq Acc Id: XM_063276135   ⟹   XP_063132205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,138,119 - 5,244,414 (+)NCBI
RefSeq Acc Id: XM_063276136   ⟹   XP_063132206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,092,108 - 5,244,414 (+)NCBI
RefSeq Acc Id: XM_063276137   ⟹   XP_063132207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,244,414 (+)NCBI
RefSeq Acc Id: XM_063276138   ⟹   XP_063132208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,548 - 5,244,414 (+)NCBI
RefSeq Acc Id: XM_063276139   ⟹   XP_063132209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,134,263 - 5,244,414 (+)NCBI
RefSeq Acc Id: XM_063276140   ⟹   XP_063132210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,138,119 - 5,244,414 (+)NCBI
RefSeq Acc Id: XM_063276141   ⟹   XP_063132211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,092 - 5,244,414 (+)NCBI
RefSeq Acc Id: XM_063276142   ⟹   XP_063132212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,170,330 - 5,244,414 (+)NCBI
RefSeq Acc Id: XR_010058817
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,126,101 - 5,217,881 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001099570 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430798 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430799 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430800 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430801 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430802 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430803 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430804 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430805 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430806 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430807 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430808 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951374 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951375 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951376 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951377 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951378 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951379 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951380 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951382 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951383 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951384 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951385 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951388 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951389 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951390 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951391 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951392 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951393 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951394 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132205 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132206 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132207 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132208 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132209 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132210 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132211 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132212 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58658 (Get FASTA)   NCBI Sequence Viewer  
  EDL93892 (Get FASTA)   NCBI Sequence Viewer  
  EDL93893 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025382
  ENSRNOP00000025382.6
  ENSRNOP00000071198
  ENSRNOP00000071198.3
  ENSRNOP00000098927
  ENSRNOP00000098927.1
  ENSRNOP00000099619
  ENSRNOP00000099619.1
  ENSRNOP00000101042
  ENSRNOP00000101042.1
  ENSRNOP00000109333.1
  ENSRNOP00000110575
  ENSRNOP00000110575.1
RefSeq Acc Id: NP_001099570   ⟸   NM_001106100
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071198   ⟸   ENSRNOT00000091370
Ensembl Acc Id: ENSRNOP00000025382   ⟸   ENSRNOT00000025381
RefSeq Acc Id: XP_038951382   ⟸   XM_039095454
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951379   ⟸   XM_039095451
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951374   ⟸   XM_039095446
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951390   ⟸   XM_039095462
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038951385   ⟸   XM_039095457
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951392   ⟸   XM_039095464
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038951393   ⟸   XM_039095465
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038951388   ⟸   XM_039095460
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038951389   ⟸   XM_039095461
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JZV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951384   ⟸   XM_039095456
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951376   ⟸   XM_039095448
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951378   ⟸   XM_039095450
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951383   ⟸   XM_039095455
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951380   ⟸   XM_039095452
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951375   ⟸   XM_039095447
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951391   ⟸   XM_039095463
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038951377   ⟸   XM_039095449
- Peptide Label: isoform X1
- UniProtKB: G3V8G1 (UniProtKB/TrEMBL),   A6KAI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951394   ⟸   XM_039095466
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063132206   ⟸   XM_063276136
- Peptide Label: isoform X1
- UniProtKB: A6KAI4 (UniProtKB/TrEMBL),   G3V8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132211   ⟸   XM_063276141
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063132207   ⟸   XM_063276137
- Peptide Label: isoform X1
- UniProtKB: A6KAI4 (UniProtKB/TrEMBL),   G3V8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132208   ⟸   XM_063276138
- Peptide Label: isoform X1
- UniProtKB: A6KAI4 (UniProtKB/TrEMBL),   G3V8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132209   ⟸   XM_063276139
- Peptide Label: isoform X1
- UniProtKB: A6KAI4 (UniProtKB/TrEMBL),   G3V8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132205   ⟸   XM_063276135
- Peptide Label: isoform X1
- UniProtKB: A6KAI4 (UniProtKB/TrEMBL),   G3V8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132210   ⟸   XM_063276140
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063132212   ⟸   XM_063276142
- Peptide Label: isoform X10
Ensembl Acc Id: ENSRNOP00000098927   ⟸   ENSRNOT00000147265
Ensembl Acc Id: ENSRNOP00000109333   ⟸   ENSRNOT00000170055
Ensembl Acc Id: ENSRNOP00000110575   ⟸   ENSRNOT00000146723
Ensembl Acc Id: ENSRNOP00000099619   ⟸   ENSRNOT00000168062
Ensembl Acc Id: ENSRNOP00000101042   ⟸   ENSRNOT00000166040
Protein Domains
Peptidase M14

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8G1-F1-model_v2 AlphaFold G3V8G1 1-1219 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306307 AgrOrtholog
BioCyc Gene G2FUF-10405 BioCyc
Ensembl Genes ENSRNOG00000018651 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025381 ENTREZGENE
  ENSRNOT00000025381.8 UniProtKB/TrEMBL
  ENSRNOT00000091370 ENTREZGENE
  ENSRNOT00000091370.3 UniProtKB/TrEMBL
  ENSRNOT00000146723 ENTREZGENE
  ENSRNOT00000146723.1 UniProtKB/TrEMBL
  ENSRNOT00000147265 ENTREZGENE
  ENSRNOT00000147265.1 UniProtKB/TrEMBL
  ENSRNOT00000166040 ENTREZGENE
  ENSRNOT00000166040.1 UniProtKB/TrEMBL
  ENSRNOT00000168062 ENTREZGENE
  ENSRNOT00000168062.1 UniProtKB/TrEMBL
  ENSRNOT00000170055.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.60.40.3120 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8369129 IMAGE-MGC_LOAD
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  CBPC1/4 UniProtKB/TrEMBL
  Cytosolic_carboxypeptidase UniProtKB/TrEMBL
  Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
KEGG Report rno:290986 UniProtKB/TrEMBL
MGC_CLONE MGC:187642 IMAGE-MGC_LOAD
NCBI Gene 290986 ENTREZGENE
PANTHER CYTOSOLIC CARBOXYPEPTIDASE UniProtKB/TrEMBL
  CYTOSOLIC CARBOXYPEPTIDASE 1 UniProtKB/TrEMBL
Pfam Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
  TPR_CCP1_N UniProtKB/TrEMBL
PhenoGen Agtpbp1 PhenoGen
PROSITE PEPTIDASE_M14 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018651 RatGTEx
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A0G2JZV3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L4P2_RAT UniProtKB/TrEMBL
  A0ABK0L6N1_RAT UniProtKB/TrEMBL
  A0ABK0L864_RAT UniProtKB/TrEMBL
  A0ABK0LF37_RAT UniProtKB/TrEMBL
  A0ABK0M5C4_RAT UniProtKB/TrEMBL
  A6KAI4 ENTREZGENE, UniProtKB/TrEMBL
  B0BN26_RAT UniProtKB/TrEMBL
  G3V8G1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-18 Agtpbp1  ATP/GTP binding carboxypeptidase 1  Agtpbp1  ATP/GTP binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Agtpbp1  ATP/GTP binding protein 1   Agtpbp1_predicted  ATP/GTP binding protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Agtpbp1_predicted  ATP/GTP binding protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED