L2hgdh (L-2-hydroxyglutarate dehydrogenase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: L2hgdh (L-2-hydroxyglutarate dehydrogenase) Rattus norvegicus
Analyze
Symbol: L2hgdh
Name: L-2-hydroxyglutarate dehydrogenase
RGD ID: 1306250
Description: Predicted to enable 2-hydroxyglutarate dehydrogenase activity. Predicted to be involved in small molecule metabolic process. Predicted to be located in membrane and mitochondrion. Human ortholog(s) of this gene implicated in 2-hydroxyglutaric aciduria; L-2-hydroxyglutaric aciduria; cerebellar ataxia; and hereditary spastic paraplegia. Orthologous to human L2HGDH (L-2-hydroxyglutarate dehydrogenase); PARTICIPATES IN butanoate metabolic pathway; INTERACTS WITH 2,6-dinitrotoluene; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: L-2-hydroxyglutarate dehydrogenase, mitochondrial; LOC314196; RGD1306250; similar to cDNA sequence BC016226
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8693,900,427 - 93,941,534 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl693,900,427 - 93,941,534 (-)EnsemblGRCr8
mRatBN7.2688,164,429 - 88,205,585 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,164,440 - 88,205,578 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,563,169 - 88,604,234 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0688,862,621 - 88,903,686 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0688,302,360 - 88,343,425 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,016,560 - 92,057,643 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,016,622 - 92,057,816 (-)Ensemblrn6Rnor6.0
Rnor_5.06101,466,089 - 101,507,172 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,730,715 - 91,771,825 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,659,422 - 86,700,511 (-)NCBICelera
RGSC_v3.1691,735,909 - 91,775,259 (-)NCBI
Cytogenetic Map6q24NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA,ISO)
mitochondrial inner membrane  (IEA)
mitochondrion  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Clinical, neuroimaging, and genetic features of L-2-hydroxyglutaric aciduria in Arab kindreds. Faiyaz-Ul-Haque M, etal., Ann Saudi Med. 2014 Mar-Apr;34(2):107-14. doi: 10.5144/0256-4947.2014.107.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Founder effect confirmation of c.241A>G mutation in the L2HGDH gene and characterization of oxidative stress parameters in six Tunisian families with L-2-hydroxyglutaric aciduria. Jellouli NK, etal., J Hum Genet. 2014 Apr;59(4):216-22. doi: 10.1038/jhg.2014.4. Epub 2014 Feb 27.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair. Rzem R, etal., PLoS One. 2015 Mar 12;10(3):e0119540. doi: 10.1371/journal.pone.0119540. eCollection 2015.
9. A novel compound heterozygous mutation in a Chinese boy with L-2-hydroxyglutaric aciduria: a case study. Tai H and Zhang Z, BMC Neurol. 2015 Jul 25;15:117. doi: 10.1186/s12883-015-0369-2.
Additional References at PubMed
PMID:16005139   PMID:17603759   PMID:18614015  


Genomics

Comparative Map Data
L2hgdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8693,900,427 - 93,941,534 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl693,900,427 - 93,941,534 (-)EnsemblGRCr8
mRatBN7.2688,164,429 - 88,205,585 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,164,440 - 88,205,578 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,563,169 - 88,604,234 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0688,862,621 - 88,903,686 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0688,302,360 - 88,343,425 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,016,560 - 92,057,643 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,016,622 - 92,057,816 (-)Ensemblrn6Rnor6.0
Rnor_5.06101,466,089 - 101,507,172 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,730,715 - 91,771,825 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,659,422 - 86,700,511 (-)NCBICelera
RGSC_v3.1691,735,909 - 91,775,259 (-)NCBI
Cytogenetic Map6q24NCBI
L2HGDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381450,242,434 - 50,312,229 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1450,237,563 - 50,312,229 (-)Ensemblhg38GRCh38
GRCh371450,709,152 - 50,778,947 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361449,778,902 - 49,848,697 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341449,782,932 - 49,848,697NCBI
Celera1430,576,287 - 30,646,077 (-)NCBICelera
Cytogenetic Map14q21.3NCBI
HuRef1430,834,630 - 30,904,412 (-)NCBIHuRef
CHM1_11450,647,804 - 50,717,581 (-)NCBICHM1_1
T2T-CHM13v2.01444,448,675 - 44,518,455 (-)NCBIT2T-CHM13v2.0
L2hgdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391269,737,210 - 69,771,648 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1269,737,207 - 69,771,647 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381269,690,436 - 69,724,874 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1269,690,433 - 69,724,873 (-)Ensemblmm10GRCm38
MGSCv371270,791,423 - 70,825,861 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361270,609,057 - 70,643,423 (-)NCBIMGSCv36mm8
Celera1270,780,829 - 70,815,274 (-)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1228.94NCBI
L2hgdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540912,485,003 - 12,535,098 (+)Ensembl
ChiLan1.0NW_00495540912,485,003 - 12,531,759 (+)NCBIChiLan1.0ChiLan1.0
L2HGDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21551,381,640 - 51,451,341 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11450,598,143 - 50,667,844 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01430,832,194 - 30,901,922 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11449,137,141 - 49,205,993 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1449,132,396 - 49,205,993 (-)EnsemblpanPan2panpan1.1
L2HGDH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1826,721,501 - 26,760,411 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl826,723,309 - 26,760,984 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha826,475,095 - 26,513,873 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0826,899,306 - 26,937,999 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl826,899,329 - 26,938,020 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1826,554,245 - 26,592,947 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0826,626,700 - 26,665,379 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0826,945,440 - 26,984,225 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
L2hgdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864058,908,636 - 58,952,971 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649515,238,738 - 15,278,840 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649515,238,726 - 15,278,840 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
L2HGDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1180,020,863 - 180,069,146 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11180,020,862 - 180,069,168 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21200,362,054 - 200,410,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
L2HGDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12427,314,306 - 27,383,379 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2427,314,283 - 27,383,342 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605315,638,882 - 15,706,112 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
L2hgdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473118,554,457 - 18,597,796 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473118,554,472 - 18,592,944 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
L2hgdh
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1783,350,710 - 83,390,939 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in L2hgdh
392 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:209
Count of miRNA genes:152
Interacting mature miRNAs:181
Transcripts:ENSRNOT00000006473
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
AI232564  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2688,164,585 - 88,164,705 (+)MAPPERmRatBN7.2
Rnor_6.0692,016,717 - 92,016,836NCBIRnor6.0
Rnor_5.06101,466,246 - 101,466,365UniSTSRnor5.0
RGSC_v3.4691,730,872 - 91,730,991UniSTSRGSC3.4
Celera686,659,579 - 86,659,698UniSTS
RH 3.4 Map6628.9UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 91 59 6 355 191 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006473   ⟹   ENSRNOP00000006473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl693,900,427 - 93,941,534 (-)Ensembl
mRatBN7.2 Ensembl688,164,440 - 88,205,536 (-)Ensembl
Rnor_6.0 Ensembl692,016,622 - 92,057,816 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094336   ⟹   ENSRNOP00000086446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl688,165,770 - 88,205,578 (-)Ensembl
RefSeq Acc Id: NM_001108028   ⟹   NP_001101498
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8693,900,427 - 93,941,534 (-)NCBI
mRatBN7.2688,164,429 - 88,205,536 (-)NCBI
Rnor_6.0692,016,560 - 92,057,643 (-)NCBI
Rnor_5.06101,466,089 - 101,507,172 (-)NCBI
RGSC_v3.4691,730,715 - 91,771,825 (-)RGD
Celera686,659,422 - 86,700,511 (-)RGD
Sequence:
RefSeq Acc Id: XM_039112252   ⟹   XP_038968180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8693,927,650 - 93,941,512 (-)NCBI
mRatBN7.2688,191,699 - 88,205,585 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101498 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968180 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03526 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006473
  ENSRNOP00000006473.4
RefSeq Acc Id: NP_001101498   ⟸   NM_001108028
- UniProtKB: A6HBX1 (UniProtKB/TrEMBL),   A0A8I6A287 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006473   ⟸   ENSRNOT00000006473
RefSeq Acc Id: XP_038968180   ⟸   XM_039112252
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000086446   ⟸   ENSRNOT00000094336
Protein Domains
FAD dependent oxidoreductase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVS2-F1-model_v2 AlphaFold D3ZVS2 1-463 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694638
Promoter ID:EPDNEW_R5161
Type:multiple initiation site
Name:L2hgdh_1
Description:L-2-hydroxyglutarate dehydrogenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0692,057,676 - 92,057,736EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306250 AgrOrtholog
BioCyc Gene G2FUF-37227 BioCyc
Ensembl Genes ENSRNOG00000004857 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006473 ENTREZGENE
  ENSRNOT00000006473.6 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
  D-Amino Acid Oxidase, subunit A, domain 2 UniProtKB/TrEMBL
InterPro FAD-dep_OxRdtase UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
KEGG Report rno:314196 UniProtKB/TrEMBL
NCBI Gene 314196 ENTREZGENE
PANTHER L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL UniProtKB/TrEMBL
  L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam DAO UniProtKB/TrEMBL
PhenoGen L2hgdh PhenoGen
RatGTEx ENSRNOG00000004857 RatGTEx
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
UniProt A0A8I6A287 ENTREZGENE
  A6HBX1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVS2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 L2hgdh  L-2-hydroxyglutarate dehydrogenase   L2hgdh_predicted  L-2-hydroxyglutarate dehydrogenase (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 L2hgdh_predicted  L-2-hydroxyglutarate dehydrogenase (predicted)  RGD1306250_predicted  similar to cDNA sequence BC016226 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1306250_predicted  similar to cDNA sequence BC016226 (predicted)  LOC314196_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314196_predicted  similar to cDNA sequence BC016226 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL