Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Eif5a2 | Rat | 1,1-dichloroethene | increases expression | ISO | Eif5a2 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of EIF5A2 mRNA | CTD | PMID:26682919 | Eif5a2 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Eif5a2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of EIF5A2 mRNA | CTD | PMID:22206623 | Eif5a2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Eif5a2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EIF5A2 mRNA | CTD | PMID:22206623 | Eif5a2 | Rat | 17beta-estradiol | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of EIF5A2 mRNA | CTD | PMID:31614463 | Eif5a2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EIF5A2 mRNA | CTD | PMID:33387578 | Eif5a2 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | 2,2',4,4',5-brominated diphenyl ether results in increased expression of EIF5A2 mRNA | CTD | PMID:26705709 | Eif5a2 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of EIF5A2 mRNA | CTD | PMID:30851411 | Eif5a2 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Eif5a2 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Eif5a2 (Mus musculus) | 6480464 | bisphenol S affects the methylation of EIF5A2 gene | CTD | PMID:31683443 | Eif5a2 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of EIF5A2 mRNA | CTD | PMID:24780913|PMID:25825206 | Eif5a2 | Rat | acrylamide | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of EIF5A2 mRNA | CTD | PMID:32763439 | Eif5a2 | Rat | all-trans-retinoic acid | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of EIF5A2 mRNA | CTD | PMID:21934132 | Eif5a2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of EIF5A2 mRNA | CTD | PMID:16483693 | Eif5a2 | Rat | antirheumatic drug | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of EIF5A2 mRNA | CTD | PMID:24449571 | Eif5a2 | Rat | arsane | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of EIF5A2 more ... | CTD | PMID:32525701 | Eif5a2 | Rat | arsenic atom | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of EIF5A2 more ... | CTD | PMID:32525701 | Eif5a2 | Rat | arsenous acid | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of EIF5A2 mRNA | CTD | PMID:30983542 | Eif5a2 | Rat | benzo[a]pyrene | decreases methylation | ISO | EIF5A2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of EIF5A2 promoter | CTD | PMID:27901495 | Eif5a2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of EIF5A2 mRNA | CTD | PMID:25181051 | Eif5a2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of EIF5A2 mRNA | CTD | PMID:33296240 | Eif5a2 | Rat | bisphenol A | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Eif5a2 | Rat | cadmium atom | multiple interactions | ISO | Eif5a2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF5A2 more ... | CTD | PMID:37325564 | Eif5a2 | Rat | cadmium dichloride | multiple interactions | ISO | Eif5a2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF5A2 more ... | CTD | PMID:37325564 | Eif5a2 | Rat | calcitriol | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of EIF5A2 mRNA | CTD | PMID:16002434 | Eif5a2 | Rat | carbon nanotube | affects expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Nanotubes, Carbon affects the expression of EIF5A2 protein | CTD | PMID:22001959 | Eif5a2 | Rat | carbon nanotube | increases expression | ISO | Eif5a2 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of EIF5A2 mRNA | CTD | PMID:25554681 | Eif5a2 | Rat | chlordecone | multiple interactions | ISO | Eif5a2 (Mus musculus) | 6480464 | Chlordecone inhibits the reaction [Biomarkers metabolite binds to EIF5A2 gene] | CTD | PMID:31084621 | Eif5a2 | Rat | chlorpyrifos | decreases expression | ISO | Eif5a2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of EIF5A2 mRNA | CTD | PMID:37019170 | Eif5a2 | Rat | cisplatin | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of EIF5A2 mRNA | CTD | PMID:27392435 | Eif5a2 | Rat | cisplatin | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of EIF5A2 mRNA | CTD | PMID:27392435 | Eif5a2 | Rat | colforsin daropate hydrochloride | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Colforsin results in decreased expression of EIF5A2 mRNA | CTD | PMID:30983542 | Eif5a2 | Rat | copper atom | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of EIF5A2 mRNA | CTD | PMID:20971185 | Eif5a2 | Rat | copper(0) | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of EIF5A2 mRNA | CTD | PMID:20971185 | Eif5a2 | Rat | copper(II) sulfate | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of EIF5A2 mRNA | CTD | PMID:19549813 | Eif5a2 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of EIF5A2 mRNA | CTD | PMID:26577399|PMID:27523638 | Eif5a2 | Rat | cyclosporin A | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of EIF5A2 mRNA | CTD | PMID:25562108 | Eif5a2 | Rat | cyclosporin A | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of EIF5A2 mRNA | CTD | PMID:27989131 | Eif5a2 | Rat | DDE | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of EIF5A2 mRNA | CTD | PMID:38568856 | Eif5a2 | Rat | dexamethasone | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Eif5a2 | Rat | diarsenic trioxide | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of EIF5A2 mRNA | CTD | PMID:30983542 | Eif5a2 | Rat | Dibutyl phosphate | affects expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of EIF5A2 mRNA | CTD | PMID:37042841 | Eif5a2 | Rat | dorsomorphin | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Eif5a2 | Rat | doxorubicin | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of EIF5A2 mRNA | CTD | PMID:29803840 | Eif5a2 | Rat | folic acid | multiple interactions | ISO | Eif5a2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of EIF5A2 mRNA | CTD | PMID:22206623 | Eif5a2 | Rat | fulvestrant | decreases methylation | ISO | EIF5A2 (Homo sapiens) | 6480464 | Fulvestrant results in decreased methylation of EIF5A2 gene | CTD | PMID:31601247 | Eif5a2 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of EIF5A2 mRNA | CTD | PMID:25539665 | Eif5a2 | Rat | GSK-J4 | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | GSK-J4 results in decreased expression of EIF5A2 mRNA | CTD | PMID:29301935 | Eif5a2 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of EIF5A2 mRNA | CTD | PMID:21396975 | Eif5a2 | Rat | indometacin | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Eif5a2 | Rat | kojic acid | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | kojic acid results in increased expression of EIF5A2 mRNA | CTD | PMID:16595896 | Eif5a2 | Rat | manganese atom | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of EIF5A2 more ... | CTD | PMID:39836092 | Eif5a2 | Rat | manganese(0) | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of EIF5A2 more ... | CTD | PMID:39836092 | Eif5a2 | Rat | manganese(II) chloride | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of EIF5A2 more ... | CTD | PMID:39836092 | Eif5a2 | Rat | methylmercury chloride | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of EIF5A2 mRNA | CTD | PMID:28001369 | Eif5a2 | Rat | ozone | multiple interactions | ISO | Eif5a2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of EIF5A2 more ... | CTD | PMID:34911549 | Eif5a2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of EIF5A2 mRNA | CTD | PMID:33387578 | Eif5a2 | Rat | phenylmercury acetate | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of EIF5A2 mRNA | CTD | PMID:26272509 | Eif5a2 | Rat | phenylmercury acetate | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Eif5a2 | Rat | rac-lactic acid | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of EIF5A2 mRNA | CTD | PMID:30851411 | Eif5a2 | Rat | SB 431542 | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Eif5a2 | Rat | sodium arsenate | multiple interactions | ISO | EIF5A2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of EIF5A2 more ... | CTD | PMID:32525701 | Eif5a2 | Rat | sodium arsenite | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of EIF5A2 mRNA | CTD | PMID:38568856 | Eif5a2 | Rat | sulforaphane | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | sulforaphane results in increased expression of EIF5A2 mRNA | CTD | PMID:31838189 | Eif5a2 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of EIF5A2 mRNA | CTD | PMID:33387578 | Eif5a2 | Rat | thimerosal | decreases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of EIF5A2 mRNA | CTD | PMID:27188386 | Eif5a2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of EIF5A2 mRNA | CTD | PMID:34492290 | Eif5a2 | Rat | titanium dioxide | decreases expression | ISO | Eif5a2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of EIF5A2 mRNA | CTD | PMID:29264374 | Eif5a2 | Rat | titanium dioxide | decreases methylation | ISO | Eif5a2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of EIF5A2 promoter | CTD | PMID:35295148 | Eif5a2 | Rat | titanium dioxide | increases methylation | ISO | Eif5a2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of EIF5A2 gene | CTD | PMID:35295148 | Eif5a2 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of EIF5A2 mRNA | CTD | PMID:33387578 | Eif5a2 | Rat | trichostatin A | affects expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of EIF5A2 mRNA | CTD | PMID:28542535 | Eif5a2 | Rat | triphenyl phosphate | affects expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of EIF5A2 mRNA | CTD | PMID:37042841 | Eif5a2 | Rat | valproic acid | affects expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of EIF5A2 mRNA | CTD | PMID:25979313 | Eif5a2 | Rat | valproic acid | increases expression | ISO | EIF5A2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of EIF5A2 mRNA | CTD | PMID:23179753|PMID:24935251|PMID:28001369|PMID:29154799 | Eif5a2 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of EIF5A2 mRNA | CTD | PMID:23555832 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















