Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dop1b | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DOP1B mRNA | CTD | PMID:22079256 | Dop1b | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DOPEY2 mRNA | CTD | PMID:36331819 | Dop1b | Rat | 1,2-dichloroethane | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of DOPEY2 mRNA | CTD | PMID:28960355 | Dop1b | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of DOPEY2 mRNA | CTD | PMID:22206623 | Dop1b | Rat | 17beta-estradiol | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Estradiol results in decreased expression of DOP1B mRNA | CTD | PMID:19167446 | Dop1b | Rat | 17beta-estradiol | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | Estradiol results in decreased expression of DOP1B mRNA | CTD | PMID:39298647 | Dop1b | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of DOPEY2 mRNA | CTD | PMID:32145629 | Dop1b | Rat | 17beta-estradiol | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of DOP1B mRNA | CTD | PMID:30165855 | Dop1b | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of DOP1B mRNA | CTD | PMID:27291303 | Dop1b | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of DOP1B protein | CTD | PMID:31675489 | Dop1b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DOP1B mRNA | CTD | PMID:19770486 | Dop1b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of DOP1B mRNA | CTD | PMID:34747641 | Dop1b | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of DOP1B mRNA | CTD | PMID:21346803 | Dop1b | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DOPEY2 mRNA | CTD | PMID:30851411 | Dop1b | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of DOP1B protein | CTD | PMID:31675489 | Dop1b | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | bisphenol S results in decreased expression of DOP1B mRNA; bisphenol S results in decreased expression more ... | CTD | PMID:33297965|PMID:39298647 | Dop1b | Rat | aflatoxin B1 | affects methylation | ISO | DOP1B (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of DOP1B intron | CTD | PMID:30157460 | Dop1b | Rat | Aflatoxin B2 alpha | affects methylation | ISO | DOP1B (Homo sapiens) | 6480464 | aflatoxin B2 affects the methylation of DOP1B intron | CTD | PMID:30157460 | Dop1b | Rat | Aroclor 1254 | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of DOP1B mRNA | CTD | PMID:23650126 | Dop1b | Rat | arsane | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DOP1B more ... | CTD | PMID:39836092 | Dop1b | Rat | arsenic atom | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DOP1B more ... | CTD | PMID:39836092 | Dop1b | Rat | arsenite(3-) | decreases methylation | ISO | DOP1B (Homo sapiens) | 6480464 | arsenite results in decreased methylation of DOP1B promoter | CTD | PMID:23974009 | Dop1b | Rat | arsenite(3-) | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to DOP1B mRNA] | CTD | PMID:32406909 | Dop1b | Rat | benzo[a]pyrene | increases mutagenesis | ISO | DOP1B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of DOP1B gene | CTD | PMID:25435355 | Dop1b | Rat | benzo[a]pyrene | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of DOP1B mRNA | CTD | PMID:19770486 | Dop1b | Rat | benzo[a]pyrene | increases methylation | ISO | DOP1B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of DOPEY2 5' UTR | CTD | PMID:27901495 | Dop1b | Rat | benzo[a]pyrene | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of DOP1B mRNA | CTD | PMID:20064835 | Dop1b | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DOP1B mRNA | CTD | PMID:20382639 | Dop1b | Rat | benzo[e]pyrene | decreases methylation | ISO | DOP1B (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of DOP1B intron | CTD | PMID:30157460 | Dop1b | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of DOPEY2 mRNA | CTD | PMID:31163220 | Dop1b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DOP1B mRNA | CTD | PMID:25181051 | Dop1b | Rat | bisphenol A | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of DOP1B protein | CTD | PMID:31675489 | Dop1b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DOP1B mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:30816183|PMID:32145629 | Dop1b | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of DOP1B gene | CTD | PMID:28505145 | Dop1b | Rat | Butylbenzyl phthalate | increases methylation | ISO | Dop1b (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of DOP1B intron | CTD | PMID:28392331 | Dop1b | Rat | cadmium atom | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DOP1B more ... | CTD | PMID:37236586 | Dop1b | Rat | cadmium dichloride | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DOP1B more ... | CTD | PMID:37236586 | Dop1b | Rat | cadmium dichloride | increases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of DOP1B mRNA | CTD | PMID:38174414 | Dop1b | Rat | caffeine | affects phosphorylation | ISO | DOP1B (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of DOP1B protein | CTD | PMID:35688186 | Dop1b | Rat | carbon nanotube | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of DOP1B mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Dop1b | Rat | carbon nanotube | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of DOP1B mRNA | CTD | PMID:25620056 | Dop1b | Rat | carnosic acid | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | salvin inhibits the reaction [sodium arsenite results in decreased expression of DOP1B mRNA] | CTD | PMID:35202923 | Dop1b | Rat | CGP 52608 | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DOPEY2 gene] | CTD | PMID:28238834 | Dop1b | Rat | chromium(6+) | affects expression | ISO | Dop1b (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of DOP1B mRNA | CTD | PMID:28472532 | Dop1b | Rat | cisplatin | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of DOP1B mRNA | CTD | PMID:27392435|PMID:27594783 | Dop1b | Rat | copper(II) sulfate | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of DOP1B mRNA | CTD | PMID:19549813 | Dop1b | Rat | coumestrol | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of DOP1B mRNA | CTD | PMID:19167446 | Dop1b | Rat | crocidolite asbestos | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of DOP1B mRNA | CTD | PMID:29279043 | Dop1b | Rat | cyclosporin A | increases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DOP1B mRNA | CTD | PMID:25562108 | Dop1b | Rat | decabromodiphenyl ether | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of DOP1B protein | CTD | PMID:31675489 | Dop1b | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of DOP1B mRNA | CTD | PMID:21266533 | Dop1b | Rat | dioxygen | affects methylation | ISO | Dop1b (Mus musculus) | 6480464 | Oxygen deficiency affects the methylation of DOP1B promoter | CTD | PMID:24205000 | Dop1b | Rat | dioxygen | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of DOP1B mRNA | CTD | PMID:30529165 | Dop1b | Rat | dioxygen | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of DOP1B mRNA | CTD | PMID:24205000 | Dop1b | Rat | epoxiconazole | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of DOP1B mRNA | CTD | PMID:35436446 | Dop1b | Rat | ethanol | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | Ethanol results in increased expression of DOP1B mRNA | CTD | PMID:19167417 | Dop1b | Rat | FR900359 | decreases phosphorylation | ISO | DOP1B (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of DOP1B protein | CTD | PMID:37730182 | Dop1b | Rat | hydrogen peroxide | affects expression | ISO | DOP1B (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of DOP1B mRNA | CTD | PMID:21179406 | Dop1b | Rat | isotretinoin | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of DOP1B mRNA | CTD | PMID:20436886 | Dop1b | Rat | manganese atom | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of DOP1B more ... | CTD | PMID:39836092 | Dop1b | Rat | manganese(0) | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of DOP1B more ... | CTD | PMID:39836092 | Dop1b | Rat | manganese(II) chloride | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of DOP1B more ... | CTD | PMID:39836092 | Dop1b | Rat | methapyrilene | decreases methylation | ISO | DOP1B (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of DOP1B intron | CTD | PMID:30157460 | Dop1b | Rat | methyl methanesulfonate | increases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of DOP1B mRNA | CTD | PMID:23649840 | Dop1b | Rat | okadaic acid | increases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of DOP1B mRNA | CTD | PMID:38832940 | Dop1b | Rat | ozone | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of DOPEY2 more ... | CTD | PMID:27106289 | Dop1b | Rat | paracetamol | increases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DOP1B mRNA | CTD | PMID:22230336|PMID:29067470 | Dop1b | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DOPEY2 mRNA | CTD | PMID:36331819 | Dop1b | Rat | pirinixic acid | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DOP1B mRNA | CTD | PMID:18301758 | Dop1b | Rat | pirinixic acid | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Dop1b | Rat | potassium chromate | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of DOP1B mRNA | CTD | PMID:22079256 | Dop1b | Rat | potassium chromate | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DOP1B mRNA | CTD | PMID:22079256 | Dop1b | Rat | potassium dichromate | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of DOP1B mRNA | CTD | PMID:23608068 | Dop1b | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of DOP1B mRNA | CTD | PMID:28903501 | Dop1b | Rat | propiconazole | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | propiconazole results in increased expression of DOP1B mRNA | CTD | PMID:21278054 | Dop1b | Rat | rac-lactic acid | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DOPEY2 mRNA | CTD | PMID:30851411 | Dop1b | Rat | sodium arsenite | decreases expression | ISO | Dop1b (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of DOP1B mRNA | CTD | PMID:35202923 | Dop1b | Rat | sodium arsenite | increases expression | ISO | Dop1b (Mus musculus) | 6480464 | sodium arsenite results in increased expression of DOP1B mRNA | CTD | PMID:36209798 | Dop1b | Rat | sodium arsenite | multiple interactions | ISO | DOP1B (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DOP1B more ... | CTD | PMID:39836092 | Dop1b | Rat | sodium arsenite | multiple interactions | ISO | Dop1b (Mus musculus) | 6480464 | salvin inhibits the reaction [sodium arsenite results in decreased expression of DOP1B mRNA] | CTD | PMID:35202923 | Dop1b | Rat | temozolomide | decreases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of DOP1B mRNA | CTD | PMID:31758290 | Dop1b | Rat | triphenyl phosphate | affects expression | ISO | DOP1B (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of DOP1B mRNA | CTD | PMID:37042841 | Dop1b | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | DOP1B (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of DOP1B mRNA | CTD | PMID:29024780 | Dop1b | Rat | urethane | increases expression | ISO | DOP1B (Homo sapiens) | 6480464 | Urethane results in increased expression of DOP1B mRNA | CTD | PMID:28818685 | Dop1b | Rat | valproic acid | affects expression | ISO | DOP1B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DOP1B mRNA | CTD | PMID:25979313 | Dop1b | Rat | valproic acid | affects expression | ISO | Dop1b (Mus musculus) | 6480464 | Valproic Acid affects the expression of DOP1B mRNA | CTD | PMID:17963808 | Dop1b | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of DOP1B mRNA | CTD | PMID:23034163 | | 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