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Gene: Auh (AU RNA binding methylglutaconyl-CoA hydratase) Rattus norvegicus

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Symbol:

Auh

Name:

AU RNA binding methylglutaconyl-CoA hydratase

RGD ID:

1306087

Description:

Predicted to enable enoyl-CoA hydratase activity; mRNA 3'-UTR binding activity; and methylglutaconyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 1 and renal tubular transport disease. Orthologous to human AUH (AU RNA binding methylglutaconyl-CoA hydratase); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

3-MG-CoA hydratase; AU RNA binding protein/enoyl-CoA hydratase; AU RNA binding protein/enoyl-Coenzyme A hydratase; AU-binding enoyl-CoA hydratase; AU-specific RNA-binding enoyl-CoA hydratase; itaconyl-CoA hydratase; LOC361215; methylglutaconyl-CoA hydratase, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AUH (AU RNA binding methylglutaconyl-CoA hydratase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Auh (AU RNA binding protein/enoyl-coenzyme A hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Auh (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AUH (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AUH (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Auh (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AUH (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AUH (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Auh (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Auh (AU RNA binding methylglutaconyl-CoA hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	AUH (AU RNA binding methylglutaconyl-CoA hydratase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Auh (AU RNA binding protein/enoyl-coenzyme A hydratase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	auh (AU RNA binding protein/enoyl-CoA hydratase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8778	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ech-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	auh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	auh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	12,481,396 - 12,576,748 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	12,481,416 - 12,602,587 (+)	Ensembl				GRCr8
mRatBN7.2	17	12,329,522 - 12,424,882 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	12,329,524 - 12,424,896 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	12,264,027 - 12,359,120 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	13,861,533 - 13,956,350 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	12,178,505 - 12,273,314 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	12,310,178 - 12,405,224 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	12,310,214 - 12,405,205 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	14,407,790 - 14,501,296 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	18,147,850 - 18,251,863 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	12,101,042 - 12,189,320 (+)	NCBI		Celera
RGSC_v3.1	17	18,141,903 - 18,251,849 (+)	NCBI
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-methylglutaconic aciduria type 1 (ISO)

genetic disease (ISO)

renal tubular transport disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,6-dinitrotoluene (EXP)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

carbon nanotube (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

diuron (EXP)

doxorubicin (ISO)

entacapone (EXP)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

genistein (EXP)

gentamycin (EXP)

glyphosate (ISO)

GSK-J4 (ISO)

indometacin (EXP)

inulin (ISO)

lead diacetate (ISO)

menadione (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

N,N-diethyl-m-toluamide (EXP)

nefazodone (EXP)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

PCB138 (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

permethrin (EXP)

phenobarbital (ISO)

PhIP (EXP)

phlorizin (ISO)

pirinixic acid (ISO)

quartz (ISO)

quercetin (EXP,ISO)

resveratrol (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP,ISO)

Soman (EXP)

sulindac (EXP)

sunitinib (ISO)

tetrachloromethane (EXP)

tetracycline (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

tolcapone (EXP)

trichloroethene (EXP)

trimellitic anhydride (ISO)

tunicamycin (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

branched-chain amino acid catabolic process (IEA)

fatty acid beta-oxidation (IBA)

L-leucine catabolic process (IEA,ISO)

Cellular Component

mitochondrion (IBA,IEA,ISO)

Molecular Function

catalytic activity (IEA)

enoyl-CoA hydratase activity (IBA,IEA,ISO)

itaconyl-CoA hydratase activity (IEA)

lyase activity (IEA)

methylglutaconyl-CoA hydratase activity (IBA,IEA,ISO)

mRNA 3'-UTR binding (IEA,ISO)

RNA binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway (ISO)

3-hydroxyisobutyric aciduria pathway (ISO)

3-methylcrotonyl CoA carboxylase 1 deficiency pathway (ISO)

3-methylglutaconic aciduria type 1 pathway (ISO)

3-methylglutaconic aciduria type 3 pathway (ISO)

isobutyryl-CoA dehydrogenase deficiency pathway (ISO)

isovaleric acidemia pathway (ISO)

maple syrup urine disease pathway (ISO)

methylmalonate semialdehyde dehydrogenase deficiency pathway (ISO)

methylmalonic acidemia pathway (ISO)

propionic acidemia pathway (ISO)

valine, leucine and isoleucine degradation pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	3-Methylglutaconic aciduria type I is caused by mutations in AUH.	IJlst L, etal., Am J Hum Genet. 2002 Dec;71(6):1463-6. Epub 2002 Nov 14.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:7892223	PMID:10072761	PMID:12477932	PMID:14651853	PMID:18614015

Genomics

Comparative Map Data

Auh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	12,481,396 - 12,576,748 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	12,481,416 - 12,602,587 (+)	Ensembl				GRCr8
mRatBN7.2	17	12,329,522 - 12,424,882 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	12,329,524 - 12,424,896 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	12,264,027 - 12,359,120 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	13,861,533 - 13,956,350 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	12,178,505 - 12,273,314 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	12,310,178 - 12,405,224 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	12,310,214 - 12,405,205 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	14,407,790 - 14,501,296 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	18,147,850 - 18,251,863 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	12,101,042 - 12,189,320 (+)	NCBI		Celera
RGSC_v3.1	17	18,141,903 - 18,251,849 (+)	NCBI
Cytogenetic Map	17	p14	NCBI

AUH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	91,213,823 - 91,361,918 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	91,213,815 - 91,361,961 (-)	Ensembl			hg38	GRCh38
GRCh37	9	93,976,105 - 94,124,200 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	93,015,926 - 93,163,996 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	91,055,663 - 91,203,730	NCBI
Celera	9	64,410,745 - 64,558,849 (-)	NCBI		Celera
Cytogenetic Map	9	q22.31	NCBI
HuRef	9	63,656,405 - 63,804,572 (-)	NCBI		HuRef
CHM1_1	9	94,122,573 - 94,270,676 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	103,379,966 - 103,528,055 (-)	NCBI		T2T-CHM13v2.0

Auh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	52,989,155 - 53,083,742 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	52,989,155 - 53,083,717 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	52,835,107 - 52,929,704 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	52,835,119 - 52,929,681 (-)	Ensembl			mm10	GRCm38
MGSCv37	13	52,930,479 - 53,025,046 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	52,847,551 - 52,942,093 (-)	NCBI		MGSCv36	mm8
Celera	13	53,911,509 - 54,006,402 (-)	NCBI		Celera
Cytogenetic Map	13	A5- B1	NCBI
cM Map	13	27.68	NCBI

Auh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955515	971,800 - 1,123,474 (+)	Ensembl
ChiLan1.0	NW_004955515	971,778 - 1,124,019 (+)	NCBI	ChiLan1.0	ChiLan1.0

AUH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	48,130,027 - 48,280,795 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	48,132,422 - 48,283,191 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	62,269,809 - 62,420,577 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	90,369,250 - 90,519,789 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

AUH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	95,547,822 - 95,707,654 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	95,547,843 - 95,707,471 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	96,001,456 - 96,161,244 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	96,148,200 - 96,308,147 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	96,148,210 - 96,308,147 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	95,780,326 - 95,939,995 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	95,500,167 - 95,659,929 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	96,260,104 - 96,419,890 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Auh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	12,840,014 - 12,999,988 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936796	161,003 - 303,250 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936796	160,335 - 302,458 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AUH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	2,398,462 - 2,546,342 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	2,398,456 - 2,546,329 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	3,074,971 - 3,222,311 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AUH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	101,654,957 - 101,799,863 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	101,653,386 - 101,799,792 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	89,980,978 - 90,122,961 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Auh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624868	1,200,800 - 1,392,461 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624868	1,200,862 - 1,392,844 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Auh
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	71,147,090 - 71,241,264 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Auh
748 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	52
Interacting mature miRNAs:	59
Transcripts:	ENSRNOT00000015786
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	43999106	Rat
2300002	Iddm36	Insulin dependent diabetes mellitus QTL 36	1.98		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	9266755	40968173	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4360057	27233623	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2120843	42054133	Rat
1582224	Epfw4	Epididymal fat weight QTL 4	3.5	0.0058	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	17	9206505	23859062	Rat
1582225	Bw67	Body weight QTL 67	6.2	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
2302377	Scl61	Serum cholesterol level QTL 61	4.36		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	17	6221998	58177198	Rat
1582226	Bw64	Body weight QTL 64	4.2	0.0017	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31706603	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4733534	49733534	Rat
1582208	Kidm32	Kidney mass QTL 32	3.9	0.0018	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	9206505	23859062	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	1	22181410	Rat
2317053	Aia25	Adjuvant induced arthritis QTL 25	2.69		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	10604694	55604694	Rat
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	1	36045694	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	1	21499218	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4733534	49733534	Rat
1581553	Pur14	Proteinuria QTL 14	5.3	0.0001	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	17	7985243	16523460	Rat
70184	BpQTLcluster14	Blood pressure QTL cluster 14	3.38		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	8574342	32199534	Rat
1582258	Bw76	Body weight QTL 76	4.6	0.0005	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	38037084	Rat
1582199	Insul5	Insulin level QTL 5	3.4	0.0119	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	17	9206505	23859062	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	43999106	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4360057	27233623	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	43999106	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2120843	22087569	Rat
1582241	Bw70	Body weight QTL 70	4.6	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
1582245	Bw73	Body weight QTL 73	4.6	0.0004	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22877318	Rat

Markers in Region

D17Rat184

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	17	12,497,206 - 12,497,429 (+)	Marker Load Pipeline
mRatBN7.2	17	12,345,331 - 12,345,554 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	12,325,985 - 12,326,207	NCBI	Rnor6.0
Rnor_5.0	17	14,423,577 - 14,423,799	UniSTS	Rnor5.0
RGSC_v3.4	17	18,157,669 - 18,157,892	RGD	RGSC3.4
RGSC_v3.4	17	18,157,670 - 18,157,892	UniSTS	RGSC3.4
Celera	17	12,110,862 - 12,111,084	UniSTS
RGSC_v3.1	17	18,157,669 - 18,157,892	RGD
SHRSP x BN Map	17	4.23	UniSTS
SHRSP x BN Map	17	4.23	RGD
Cytogenetic Map	17	p14	UniSTS

RH128092

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	12,424,457 - 12,424,666 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	12,404,786 - 12,404,994	NCBI	Rnor6.0
Rnor_5.0	17	14,500,858 - 14,501,066	UniSTS	Rnor5.0
RGSC_v3.4	17	18,251,425 - 18,251,633	UniSTS	RGSC3.4
Celera	17	12,188,882 - 12,189,090	UniSTS
RH 3.4 Map	1	310.32	UniSTS
Cytogenetic Map	17	p14	UniSTS

RAN

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	12,347,191 - 12,348,109 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	12,327,845 - 12,328,762	NCBI	Rnor6.0
Rnor_5.0	17	14,425,437 - 14,426,354	UniSTS	Rnor5.0
Celera	17	12,112,722 - 12,113,639	UniSTS
Cytogenetic Map	17	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008771499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039095856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005495293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005495294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015786 ⟹ ENSRNOP00000015786

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,421 - 12,576,743 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,329,524 - 12,424,881 (+)	Ensembl
Rnor_6.0 Ensembl	17	12,310,214 - 12,405,205 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096716 ⟹ ENSRNOP00000090436

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,416 - 12,576,743 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,329,524 - 12,424,881 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100823 ⟹ ENSRNOP00000083165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,416 - 12,515,504 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,329,524 - 12,363,629 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115280 ⟹ ENSRNOP00000077598

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,421 - 12,577,393 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,329,540 - 12,424,882 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115684 ⟹ ENSRNOP00000077435

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,416 - 12,503,978 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,329,524 - 12,352,103 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116031 ⟹ ENSRNOP00000095770

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,421 - 12,602,587 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,335,512 - 12,424,896 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117360 ⟹ ENSRNOP00000095703

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,421 - 12,573,427 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,329,524 - 12,421,561 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000167904 ⟹ ENSRNOP00000108951

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,481,421 - 12,556,394 (+)	Ensembl

RefSeq Acc Id:

NM_001399250 ⟹ NP_001386179

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,481,421 - 12,576,748 (+)	NCBI
mRatBN7.2	17	12,329,546 - 12,424,882 (+)	NCBI

RefSeq Acc Id:

XM_006253675 ⟹ XP_006253737

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,481,400 - 12,576,748 (+)	NCBI
mRatBN7.2	17	12,329,525 - 12,424,882 (+)	NCBI
Rnor_6.0	17	12,310,178 - 12,405,210 (+)	NCBI
Rnor_5.0	17	14,407,790 - 14,501,296 (+)	NCBI

Sequence:

show sequence

GGGCGGAGCCTGGCCGCGGGCGCCCGCTGTAAACATACAATATGGCGGCGGCGGCTGCTCCCGG
CGCTCTGGGCGCCTTGAGTGCGGGTCGGGTCCGCCTGGTGGCCGCGTGCTGCGCGCGACTAGGC
TCTGCGGCATGGGCTAGGGGTACCGCCCCGAGGAGGGGCTACAGCTCTGAGGTGAAAACCGAGG
ATGAGCTGCGCGTGCGGCACCTGGAGGAGGAGAACCGAGGCATTGTGGTGCTTGGAATTAACAG
AGCTTATGGGAAAAATTCACTCAGTAAAAATCTTCTCAAAATGTTATCAAAAGCGGTGGACGCA
TTAAAATCGGATAAGAAAGTTCGGACCATTATCATCAGAAGCGAAGTCCCTGGGATATTCTGTG
CTGGCGCTGACCTTAAGGAAAGAGCCAAGATGCATTCCAGTGAAGTCGGTCCCTTTGTCTCCAA
GATCCGAGCAGTGATCAATGACATCGCTTCTTCTGCAAAAATGGGCCTGGTGGAAACGAAGTTG
GCGATTATCCCTGGTGGAGGAGGGACACAGAGATTACCACGTGCCATCGGGATGGCCCTGGCAA
AGGAGCTCATCTTCTCTGCACGCGTTCTTGACGGTCAGGAGGCCAAAGCCGTGGGCTTGATCAG
CCACGTGTTAGAACAGAACCAGGAAGGGGATGCTGCCTACAGGAAGGCGCTGGACCTGGCAAGA
GAGTTTCTACCTCAGGGGCCTGTTGCCATGAGAGTGGCCAAACTAGCAATTAACCAAGGCATGG
AGGTTGACTTAGTGACAGGGTTAGCCATAGAAGAAGCCTGCTATGCTCAGACCATCTCAACGAA
GGACAGACTGGAAGGTCTTCTTGCTTTCAAGGAGAAAAGACCCCCTCGCTACAAGGGAGAGTAG
GGGGAGCGCCCGAGACGCCCTCCCTGGAGTGCCAGAAGTGTTTCAGAGCCGCCCCACGCTGCCA
CGGGGAATCTCGATGACCAAAGTGGAGAGTGGGTTCTCACTACACCTGGAGCAGGCCCGTCTAT
ACTCAAGCCACTGTGCGCCATGTCCTATTTATTCAGATTTATAAAGCTAGCCATGTCCGCAGTC
AGAACACATAAAAATTAGGTGTATGTTTTTAATATTTCCCGCATATCAGGCTTTGTCGTTAATT
TTTTAATGTGAATAATTTATATTGCACACTCTAGGGAATAATCGATTGTATGTCTACTGTGCTG
CATTAAGAAAATAAAACTATTTCTGTATCCCAAAAA

hide sequence

RefSeq Acc Id:

XM_008771499 ⟹ XP_008769721

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,481,423 - 12,576,748 (+)	NCBI
mRatBN7.2	17	12,329,886 - 12,424,882 (+)	NCBI
Rnor_6.0	17	12,310,430 - 12,405,210 (+)	NCBI

Sequence:

show sequence

CGAGGCCGCGGAGGTCGGCCCGGCTGCCTCTGAGGCCCGAGGGTACGGTGGCCCTCCGGGTTCA
GCCTGCATGGTGATGCTGCTCGGTCCTGGGGTCTCTCCAGCCAAGGTCAATGCGGAGTGTGTAG
TACAGGGCCAGGGTTGCATCTTGCTGTGTAATAGCTCCCTGTTACCTCAGGCGTCAGTGCGAGA
GTTGTAGGAGCTGCAGCGGGGATGCCTTTTTATTATCCGAGAGAATATTAAATTAGAAGCATCA
CCCTTTTGCACATTTTATCCCGGAGAGTTAGTTTTGGGGGACTGTTGCACCTCACTTAAAGAAT
TTTGAACGCTTTAAAAAAATTTTTTTTTGCCTTGCTGAGCTCCGTGGGGGTAAATAATGAGGCT
ATTCATCTTGCCCTTGGGCTTATTATCGTGGGAGGAGACAGATATATTAGTGCACAACAGCGGG
TGGAAGGCTATGAGAAGGTAAGATGCAGAGGAATATCGAGTTTCTTAACTATAGTGATGGAGGA
GGTGGAATGAGGTATAGCCCAGGAAGGGAGGACCACTCTGCATTTTGACATACATTTATAGGAT
GCTGTAATCTGTTAAGAAGACGCGGAAAATAAGTCAGAATGGCTGTCTCCTTAGAAGCTCTCCT
GTGTATTGAAGGTCAGATGATGCTTGCTTCAAGGCTTGTTGAGAACCCCGAAATGCCTGCAGGG
TTAATCTCTCACTGTATATCCTAGGCTGCCCTGGAAGTTAAGATCCCCAGACTTAAAAAGTGCT
GGGATCACAGGGTTGAGCCACAGTGCCTACTCCAAGGCATTCTGCGGATGGTGACCCTGGAGAC
TGACTGTTCTGATGCAAAGTTCTCTGTGCTCCGCCCATCGAATATATCAAGCAGAATCATGTAC
TCGATGATGGTGCCCTTGTGGAGACGAGATGAGGTTACTGGGTATTGACAGTTGAGCAGCCTGT
GCGGGGTGCTCAGAAGTATGGGGAGTCGTTTTGTTTCTTGTTCATTCAAGCCTTCTGAGACAGT
GGAATGGTCAAGATGATGGAGATGTTTATTTGGGAAATTTCGGAAGACAAGTCTGGTGTGACAG
AGTTGCAGGAAGCTCAGATGGGACCTTCTTAAGACAGGCCTGGAATCATTAAAGCCCTGAGTGC
CAGTCTTTTGGGCATTGTGGTGCTTGGAATTAACAGAGCTTATGGGAAAAATTCACTCAGTAAA
AATCTTCTCAAAATGTTATCAAAAGCGGTGGACGCATTAAAATCGGATAAGAAAGTTCGGACCA
TTATCATCAGAAGCGAAGTCCCTGGGATATTCTGTGCTGGCGCTGACCTTAAGGAAAGAGCCAA
GATGCATTCCAGTGAAGTCGGTCCCTTTGTCTCCAAGATCCGAGCAGTGATCAATGACATCGCT
AACCTTCCTGTGCCCACCATCGCTGCCATAGATGGCCTGGCCCTAGGAGGGGGCCTGGAGCTGG
CTTTAGCGTGTGACATTCGAGTAGCAGCTTCTTCTGCAAAAATGGGCCTGGTGGAAACGAAGTT
GGCGATTATCCCTGGTGGAGGAGGGACACAGAGATTACCACGTGCCATCGGGATGGCCCTGGCA
AAGGAGCTCATCTTCTCTGCACGCGTTCTTGACGGTCAGGAGGCCAAAGCCGTGGGCTTGATCA
GCCACGTGTTAGAACAGAACCAGGAAGGGGATGCTGCCTACAGGAAGGCGCTGGACCTGGCAAG
AGAGTTTCTACCTCAGGGGCCTGTTGCCATGAGAGTGGCCAAACTAGCAATTAACCAAGGCATG
GAGGTTGACTTAGTGACAGGGTTAGCCATAGAAGAAGCCTGCTATGCTCAGACCATCTCAACGA
AGGACAGACTGGAAGGTCTTCTTGCTTTCAAGGAGAAAAGACCCCCTCGCTACAAGGGAGAGTA
GGGGGAGCGCCCGAGACGCCCTCCCTGGAGTGCCAGAAGTGTTTCAGAGCCGCCCCACGCTGCC
ACGGGGAATCTCGATGACCAAAGTGGAGAGTGGGTTCTCACTACACCTGGAGCAGGCCCGTCTA
TACTCAAGCCACTGTGCGCCATGTCCTATTTATTCAGATTTATAAAGCTAGCCATGTCCGCAGT
CAGAACACATAAAAATTAGGTGTATGTTTTTAATATTTCCCGCATATCAGGCTTTGTCGTTAAT
TTTTTAATGTGAATAATTTATATTGCACACTCTAGGGAATAATCGATTGTATGTCTACTGTGCT
GCATTAAGAAAATAAAACTATTTCTGTATCCCAAAAA

hide sequence

RefSeq Acc Id:

XM_039095856 ⟹ XP_038951784

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,481,397 - 12,576,748 (+)	NCBI
mRatBN7.2	17	12,329,524 - 12,424,882 (+)	NCBI

RefSeq Acc Id:

XR_005495293

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,481,399 - 12,571,093 (+)	NCBI
mRatBN7.2	17	12,329,525 - 12,419,228 (+)	NCBI

RefSeq Acc Id:

XR_005495294

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,481,396 - 12,571,093 (+)	NCBI
mRatBN7.2	17	12,329,524 - 12,419,228 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001386179	(Get FASTA)	NCBI Sequence Viewer
	XP_006253737	(Get FASTA)	NCBI Sequence Viewer
	XP_008769721	(Get FASTA)	NCBI Sequence Viewer
	XP_038951784	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98065	(Get FASTA)	NCBI Sequence Viewer
	EDL98066	(Get FASTA)	NCBI Sequence Viewer
	EDL98067	(Get FASTA)	NCBI Sequence Viewer
	EDL98068	(Get FASTA)	NCBI Sequence Viewer
	EDL98069	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015786
	ENSRNOP00000015786.5
	ENSRNOP00000090436
GenBank Protein	F1LU71	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_006253737 ⟸ XM_006253675
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AAT9 (UniProtKB/TrEMBL), A0A8I5Y7Q4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAAAAPGALGALSAGRVRLVAACCARLGSAAWARGTAPRRGYSSEVKTEDELRVRHLEEENRG IVVLGINRAYGKNSLSKNLLKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSS EVGPFVSKIRAVINDIASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQE AKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEAC YAQTISTKDRLEGLLAFKEKRPPRYKGE hide sequence

RefSeq Acc Id:	XP_008769721 ⟸ XM_008771499
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6B3A4 (UniProtKB/TrEMBL), A6J6R8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPV PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELI FSARVLDGQEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDL VTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE hide sequence

Ensembl Acc Id:

ENSRNOP00000015786 ⟸ ENSRNOT00000015786

RefSeq Acc Id:	XP_038951784 ⟸ XM_039095856
- Peptide Label:	isoform X3
- UniProtKB:	A6J6R7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000083165 ⟸ ENSRNOT00000100823

Ensembl Acc Id:

ENSRNOP00000095770 ⟸ ENSRNOT00000116031

Ensembl Acc Id:

ENSRNOP00000090436 ⟸ ENSRNOT00000096716

Ensembl Acc Id:

ENSRNOP00000077598 ⟸ ENSRNOT00000115280

Ensembl Acc Id:

ENSRNOP00000095703 ⟸ ENSRNOT00000117360

Ensembl Acc Id:

ENSRNOP00000077435 ⟸ ENSRNOT00000115684

RefSeq Acc Id:	NP_001386179 ⟸ NM_001399250
- UniProtKB:	F1LU71 (UniProtKB/Swiss-Prot), A0A8I5Y7Q4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000108951 ⟸ ENSRNOT00000167904

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LU71-F1-model_v2	AlphaFold	F1LU71	1-315	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700334

Promoter ID:

EPDNEW_R10858

Type:

multiple initiation site

Name:

Auh_1

Description:

AU RNA binding methylglutaconyl-CoA hydratase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	12,310,199 - 12,310,259	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306087	AgrOrtholog
BioCyc Gene	G2FUF-10109	BioCyc
BioCyc Pathway	LEU-DEG2-PWY [L-leucine degradation I]	BioCyc
BioCyc Pathway Image	LEU-DEG2-PWY	BioCyc
Ensembl Genes	ENSRNOG00000011684	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000015786	ENTREZGENE
	ENSRNOT00000015786.8	UniProtKB/Swiss-Prot
	ENSRNOT00000096716	ENTREZGENE
	ENSRNOT00000167904	ENTREZGENE
Gene3D-CATH	1.10.12.10	UniProtKB/Swiss-Prot
	2-enoyl-CoA Hydratase, Chain A, domain 1	UniProtKB/Swiss-Prot
InterPro	ClpP/crotonase-like_dom_sf	UniProtKB/Swiss-Prot
	Enoyl-CoA_hyd/isom_CS	UniProtKB/Swiss-Prot
	Enoyl-CoA_hydra/iso	UniProtKB/Swiss-Prot
	Enoyl-CoA_hydra_C	UniProtKB/Swiss-Prot
NCBI Gene	361215	ENTREZGENE
PANTHER	ENOYL-COA HYDRATASE-RELATED	UniProtKB/Swiss-Prot
	METHYLGLUTACONYL-COA HYDRATASE, MITOCHONDRIAL	UniProtKB/Swiss-Prot
Pfam	ECH_1	UniProtKB/Swiss-Prot
PhenoGen	Auh	PhenoGen
PROSITE	ENOYL_COA_HYDRATASE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000011684	RatGTEx
Superfamily-SCOP	SSF52096	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y7Q4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZJH2_RAT	UniProtKB/TrEMBL
	A0A8I5ZWD4_RAT	UniProtKB/TrEMBL
	A0A8I6AAT9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B3A4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GL97_RAT	UniProtKB/TrEMBL
	A0ABK0M359_RAT	UniProtKB/TrEMBL
	A6J6R7	ENTREZGENE, UniProtKB/TrEMBL
	A6J6R8	ENTREZGENE, UniProtKB/TrEMBL
	AUHM_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-27	Auh	AU RNA binding methylglutaconyl-CoA hydratase	Auh	AU RNA binding protein/enoyl-CoA hydratase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-07-28	Auh	AU RNA binding protein/enoyl-CoA hydratase	Auh	AU RNA binding protein/enoyl-coenzyme A hydratase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Auh	AU RNA binding protein/enoyl-coenzyme A hydratase	Auh_predicted	AU RNA binding protein/enoyl-coenzyme A hydratase (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Auh_predicted	AU RNA binding protein/enoyl-coenzyme A hydratase (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways