Inpp1 (inositol polyphosphate-1-phosphatase) - Rat Genome Database

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Pathways
Gene: Inpp1 (inositol polyphosphate-1-phosphatase) Rattus norvegicus
Analyze
Symbol: Inpp1
Name: inositol polyphosphate-1-phosphatase
RGD ID: 1306071
Description: Predicted to enable inositol-1,4-bisphosphate 1-phosphatase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Orthologous to human INPP1 (inositol polyphosphate-1-phosphatase); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inositol polyphosphate 1-phosphatase; LOC316376
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8956,161,816 - 56,209,774 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl956,161,852 - 56,234,569 (+)EnsemblGRCr8
mRatBN7.2948,688,037 - 48,717,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl948,669,901 - 48,717,793 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx957,248,196 - 57,259,847 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0962,371,024 - 62,382,675 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0960,667,016 - 60,678,667 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0953,544,602 - 53,574,303 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,546,018 - 53,574,690 (+)Ensemblrn6Rnor6.0
Rnor_5.0953,211,337 - 53,240,916 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4945,681,642 - 45,693,321 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera946,375,403 - 46,387,081 (+)NCBICelera
RGSC_v3.1945,683,055 - 45,694,730 (+)NCBI
Cytogenetic Map9q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
Allylamine  (EXP)
alpha-pinene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
camptothecin  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
GW 4064  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
methyl methanesulfonate  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Inpp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8956,161,816 - 56,209,774 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl956,161,852 - 56,234,569 (+)EnsemblGRCr8
mRatBN7.2948,688,037 - 48,717,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl948,669,901 - 48,717,793 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx957,248,196 - 57,259,847 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0962,371,024 - 62,382,675 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0960,667,016 - 60,678,667 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0953,544,602 - 53,574,303 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,546,018 - 53,574,690 (+)Ensemblrn6Rnor6.0
Rnor_5.0953,211,337 - 53,240,916 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4945,681,642 - 45,693,321 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera946,375,403 - 46,387,081 (+)NCBICelera
RGSC_v3.1945,683,055 - 45,694,730 (+)NCBI
Cytogenetic Map9q22NCBI
INPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382190,343,589 - 190,371,665 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2190,340,590 - 190,371,665 (+)Ensemblhg38GRCh38
GRCh372191,208,315 - 191,236,391 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362190,916,684 - 190,944,552 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342191,033,940 - 191,061,813NCBI
Celera2184,803,198 - 184,831,393 (+)NCBICelera
Cytogenetic Map2q32.2NCBI
HuRef2183,068,052 - 183,096,206 (+)NCBIHuRef
CHM1_12191,214,005 - 191,242,200 (+)NCBICHM1_1
T2T-CHM13v2.02190,824,234 - 190,861,235 (+)NCBIT2T-CHM13v2.0
Inpp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39152,824,584 - 52,856,847 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl152,824,586 - 52,856,847 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38152,785,425 - 52,817,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl152,785,427 - 52,817,688 (-)Ensemblmm10GRCm38
MGSCv37152,846,262 - 52,874,532 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36152,733,967 - 52,762,082 (-)NCBIMGSCv36mm8
Celera153,330,233 - 53,358,511 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.99NCBI
Inpp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554038,713,565 - 8,726,077 (-)Ensembl
ChiLan1.0NW_0049554038,713,565 - 8,742,725 (-)NCBIChiLan1.0ChiLan1.0
INPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21393,033,029 - 93,065,318 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B93,052,536 - 93,080,302 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B77,652,045 - 77,680,013 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B195,569,417 - 195,597,898 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B195,569,417 - 195,597,898 (+)EnsemblpanPan2panpan1.1
INPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137975,286 - 987,570 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37976,559 - 985,772 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha371,912,184 - 1,938,080 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.037850,763 - 874,681 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl37859,697 - 873,010 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.137860,949 - 886,869 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.037828,719 - 852,557 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.037857,136 - 883,050 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Inpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303149,044,924 - 149,071,510 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365067,766,068 - 7,793,210 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365067,767,126 - 7,793,111 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1594,956,532 - 94,987,279 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11594,956,535 - 94,987,286 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215106,341,215 - 106,371,713 (+)NCBISscrofa10.2Sscrofa10.2susScr3
INPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11075,852,262 - 75,880,494 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1075,869,115 - 75,880,492 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040123,591,514 - 123,619,697 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inpp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248545,660,648 - 5,686,628 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Inpp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14122,505,277 - 122,537,153 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Inpp1
269 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:36
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000016842
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)93145606157460683Rat

Markers in Region
U27295  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2948,717,621 - 48,717,772 (+)MAPPERmRatBN7.2
Rnor_6.0953,574,132 - 53,574,282NCBIRnor6.0
Rnor_5.0953,240,595 - 53,240,745UniSTSRnor5.0
RGSC_v3.4945,693,150 - 45,693,300UniSTSRGSC3.4
Celera946,386,910 - 46,387,060UniSTS
Cytogenetic Map9q22UniSTS
RH134726  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2948,717,551 - 48,717,760 (+)MAPPERmRatBN7.2
Rnor_6.0953,574,062 - 53,574,270NCBIRnor6.0
Rnor_5.0953,240,525 - 53,240,733UniSTSRnor5.0
RGSC_v3.4945,693,080 - 45,693,288UniSTSRGSC3.4
Celera946,386,840 - 46,387,048UniSTS
Cytogenetic Map9q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC086600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016842   ⟹   ENSRNOP00000016842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl956,161,852 - 56,209,769 (+)Ensembl
mRatBN7.2 Ensembl948,669,901 - 48,717,793 (+)Ensembl
Rnor_6.0 Ensembl953,546,018 - 53,574,690 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109452   ⟹   ENSRNOP00000096460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl956,180,058 - 56,210,118 (+)Ensembl
mRatBN7.2 Ensembl948,688,288 - 48,717,793 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112625   ⟹   ENSRNOP00000091276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl956,184,009 - 56,210,134 (+)Ensembl
mRatBN7.2 Ensembl948,688,097 - 48,717,793 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149571   ⟹   ENSRNOP00000109194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl956,161,864 - 56,210,134 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000152190   ⟹   ENSRNOP00000111328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl956,180,058 - 56,234,569 (+)Ensembl
RefSeq Acc Id: NM_001012131   ⟹   NP_001012131
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,198,095 - 56,209,774 (+)NCBI
mRatBN7.2948,706,114 - 48,717,793 (+)NCBI
Rnor_6.0953,562,624 - 53,574,303 (+)NCBI
Rnor_5.0953,211,337 - 53,240,916 (+)NCBI
RGSC_v3.4945,681,642 - 45,693,321 (+)RGD
Celera946,375,403 - 46,387,081 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244899   ⟹   XP_006244961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,180,386 - 56,209,774 (+)NCBI
mRatBN7.2948,688,065 - 48,717,793 (+)NCBI
Rnor_6.0953,544,602 - 53,574,303 (+)NCBI
Rnor_5.0953,211,337 - 53,240,916 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767091   ⟹   XP_008765313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,181,751 - 56,209,774 (+)NCBI
mRatBN7.2948,689,764 - 48,717,793 (+)NCBI
Rnor_6.0953,554,271 - 53,574,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767092   ⟹   XP_008765314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,180,502 - 56,209,774 (+)NCBI
mRatBN7.2948,688,478 - 48,717,793 (+)NCBI
Rnor_6.0953,544,970 - 53,574,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083592   ⟹   XP_038939520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,180,296 - 56,209,774 (+)NCBI
mRatBN7.2948,688,037 - 48,717,793 (+)NCBI
RefSeq Acc Id: XM_039083595   ⟹   XP_038939523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,180,296 - 56,209,774 (+)NCBI
mRatBN7.2948,688,037 - 48,717,793 (+)NCBI
RefSeq Acc Id: XM_063267168   ⟹   XP_063123238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,161,816 - 56,209,774 (+)NCBI
RefSeq Acc Id: XM_063267169   ⟹   XP_063123239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,161,842 - 56,209,774 (+)NCBI
RefSeq Acc Id: XM_063267170   ⟹   XP_063123240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,180,296 - 56,209,774 (+)NCBI
RefSeq Acc Id: XM_063267172   ⟹   XP_063123242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,180,502 - 56,209,774 (+)NCBI
RefSeq Acc Id: XM_063267173   ⟹   XP_063123243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8956,181,750 - 56,209,774 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001012131 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419584 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419593 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419594 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419595 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419596 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419597 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419598 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419599 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419600 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419601 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419602 (Get FASTA)   NCBI Sequence Viewer  
  NP_001419603 (Get FASTA)   NCBI Sequence Viewer  
  XP_006244961 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765313 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765314 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939520 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939523 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123238 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123239 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123240 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123242 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123243 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86600 (Get FASTA)   NCBI Sequence Viewer  
  EDL99104 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016842
  ENSRNOP00000016842.5
  ENSRNOP00000091276
  ENSRNOP00000091276.1
  ENSRNOP00000096460
  ENSRNOP00000096460.1
  ENSRNOP00000109194.1
  ENSRNOP00000111328.1
RefSeq Acc Id: NP_001012131   ⟸   NM_001012131
- UniProtKB: Q5RJK6 (UniProtKB/TrEMBL),   A6INV6 (UniProtKB/TrEMBL),   A0A8I6ALU7 (UniProtKB/TrEMBL),   A0A8I6GJG8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244961   ⟸   XM_006244899
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008765314   ⟸   XM_008767092
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008765313   ⟸   XM_008767091
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000016842   ⟸   ENSRNOT00000016842
RefSeq Acc Id: XP_038939520   ⟸   XM_039083592
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939523   ⟸   XM_039083595
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000091276   ⟸   ENSRNOT00000112625
Ensembl Acc Id: ENSRNOP00000096460   ⟸   ENSRNOT00000109452
RefSeq Acc Id: XP_063123238   ⟸   XM_063267168
- Peptide Label: isoform X1
- UniProtKB: F7FA04 (UniProtKB/TrEMBL),   A0A8I6GJG8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123239   ⟸   XM_063267169
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063123240   ⟸   XM_063267170
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063123242   ⟸   XM_063267172
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063123243   ⟸   XM_063267173
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000109194   ⟸   ENSRNOT00000149571
Ensembl Acc Id: ENSRNOP00000111328   ⟸   ENSRNOT00000152190

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RJK6-F1-model_v2 AlphaFold Q5RJK6 1-396 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306071 AgrOrtholog
BioCyc Gene G2FUF-27617 BioCyc
BioCyc Pathway PWY-6363 [D-myo-inositol (1,4,5)-trisphosphate degradation] BioCyc
BioCyc Pathway Image PWY-6363 BioCyc
Ensembl Genes ENSRNOG00000012375 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016842 ENTREZGENE
  ENSRNOT00000016842.7 UniProtKB/TrEMBL
  ENSRNOT00000109452 ENTREZGENE
  ENSRNOT00000109452.2 UniProtKB/TrEMBL
  ENSRNOT00000112625 ENTREZGENE
  ENSRNOT00000112625.2 UniProtKB/TrEMBL
  ENSRNOT00000149571.1 UniProtKB/TrEMBL
  ENSRNOT00000152190.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.190.80 UniProtKB/TrEMBL
  4.10.460.10 UniProtKB/TrEMBL
  Fructose-1,6-Bisphosphatase, subunit A, domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7314378 IMAGE-MGC_LOAD
InterPro CysQ/Inositol_MonoPase UniProtKB/TrEMBL
  Inositol_monoP_metal-BS UniProtKB/TrEMBL
  Inositol_monophosphatase UniProtKB/TrEMBL
  Inositol_monophosphatase_CS UniProtKB/TrEMBL
  INPP1_dom_1 UniProtKB/TrEMBL
KEGG Report rno:316376 UniProtKB/TrEMBL
MGC_CLONE MGC:105596 IMAGE-MGC_LOAD
NCBI Gene 316376 ENTREZGENE
PANTHER 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 UniProtKB/TrEMBL
  INOSITOL POLYPHOSPHATE 1-PHOSPHATASE UniProtKB/TrEMBL
Pfam Inositol_P UniProtKB/TrEMBL
PharmGKB INPP1 RGD
PhenoGen Inpp1 PhenoGen
PROSITE IMP_1 UniProtKB/TrEMBL
  IMP_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012375 RatGTEx
Superfamily-SCOP Carbohydrate phosphatase UniProtKB/TrEMBL
UniProt A0A8I6ALU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJG8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LV86_RAT UniProtKB/TrEMBL
  A0ABK0M6Q9_RAT UniProtKB/TrEMBL
  A6INV6 ENTREZGENE, UniProtKB/TrEMBL
  F7FA04 ENTREZGENE, UniProtKB/TrEMBL
  Q5RJK6 ENTREZGENE
UniProt Secondary Q5RJK6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Inpp1  inositol polyphosphate-1-phosphatase  Inpp1_predicted  inositol polyphosphate-1-phosphatase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Inpp1_predicted  inositol polyphosphate-1-phosphatase (predicted)      Symbol and Name status set to approved 70820 APPROVED