Trmt1 (tRNA methyltransferase 1) - Rat Genome Database

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Gene: Trmt1 (tRNA methyltransferase 1) Rattus norvegicus
Analyze
Symbol: Trmt1
Name: tRNA methyltransferase 1
RGD ID: 1305992
Description: Predicted to enable tRNA (guanine(26)-N2)-dimethyltransferase activity. Predicted to be involved in tRNA N2-guanine methylation. Predicted to be active in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 68. Orthologous to human TRMT1 (tRNA methyltransferase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC288914; N(2),N(2)-dimethylguanosine tRNA methyltransferase; RGD1305992; similar to D8Ertd812e protein; TRM1 tRNA methyltransferase 1 homolog; TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae); tRNA (guanine(26)-N(2))-dimethyltransferase; tRNA methyltransferase 1 homolog; tRNA methyltransferase 1 homolog (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81940,361,583 - 40,374,971 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1940,361,583 - 40,374,622 (-)EnsemblGRCr8
mRatBN7.21923,456,756 - 23,471,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,456,756 - 23,466,956 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1930,279,620 - 30,289,802 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,933,997 - 30,944,179 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01933,156,692 - 33,166,874 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01925,798,262 - 25,813,458 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,803,262 - 25,813,467 (+)Ensemblrn6Rnor6.0
Rnor_5.01936,775,694 - 36,789,077 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41925,119,864 - 25,130,026 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1923,010,440 - 23,020,602 (-)NCBICelera
RGSC_v3.11925,124,689 - 25,134,852 (-)NCBI
Cytogenetic Map19q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
choline  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (ISO)
methimazole  (EXP)
nefazodone  (EXP)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
mitochondrion  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10982862   PMID:22658674   PMID:34800366  


Genomics

Comparative Map Data
Trmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81940,361,583 - 40,374,971 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1940,361,583 - 40,374,622 (-)EnsemblGRCr8
mRatBN7.21923,456,756 - 23,471,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,456,756 - 23,466,956 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1930,279,620 - 30,289,802 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,933,997 - 30,944,179 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01933,156,692 - 33,166,874 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01925,798,262 - 25,813,458 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,803,262 - 25,813,467 (+)Ensemblrn6Rnor6.0
Rnor_5.01936,775,694 - 36,789,077 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41925,119,864 - 25,130,026 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1923,010,440 - 23,020,602 (-)NCBICelera
RGSC_v3.11925,124,689 - 25,134,852 (-)NCBI
Cytogenetic Map19q11NCBI
TRMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381913,104,907 - 13,116,740 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1913,104,899 - 13,117,567 (-)Ensemblhg38GRCh38
GRCh371913,215,721 - 13,227,554 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361913,076,715 - 13,088,332 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1913,106,119 - 13,117,969 (-)NCBICelera
Cytogenetic Map19p13.13NCBI
HuRef1912,788,354 - 12,799,966 (-)NCBIHuRef
CHM1_11913,216,745 - 13,228,558 (-)NCBICHM1_1
T2T-CHM13v2.01913,230,119 - 13,241,953 (-)NCBIT2T-CHM13v2.0
Trmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,412,953 - 85,426,437 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl885,412,936 - 85,426,437 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38884,686,324 - 84,699,808 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl884,686,307 - 84,699,808 (+)Ensemblmm10GRCm38
MGSCv37887,213,146 - 87,223,707 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36887,579,383 - 87,589,892 (+)NCBIMGSCv36mm8
Celera888,989,136 - 88,999,879 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.02NCBI
Trmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541532,126,444 - 32,135,516 (-)Ensembl
ChiLan1.0NW_00495541532,126,630 - 32,136,770 (-)NCBIChiLan1.0ChiLan1.0
LOC100991487
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X144,963,764 - 144,966,456 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X144,967,380 - 144,970,058 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X134,674,474 - 134,676,801 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X145,052,491 - 145,054,526 (+)NCBIPanPan1.1PanPan1.1panPan2
TRMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,100,794 - 49,108,734 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,101,158 - 49,108,732 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2048,973,874 - 48,981,271 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02049,618,366 - 49,625,763 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2049,618,440 - 49,625,766 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12048,829,925 - 48,837,320 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,256,279 - 49,263,674 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,498,686 - 49,506,084 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Trmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,205,305 - 208,212,559 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366592,140,932 - 2,149,728 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366592,142,151 - 2,149,373 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl265,940,125 - 65,949,324 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1265,940,122 - 65,949,324 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,237,279 - 66,245,843 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,786,279 - 11,799,270 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl611,785,730 - 11,799,730 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660747,985,125 - 7,997,496 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624901650,202 - 660,076 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624901650,444 - 659,921 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Trmt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11715,593,362 - 15,605,879 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Trmt1
47 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:356
Count of miRNA genes:213
Interacting mature miRNAs:248
Transcripts:ENSRNOT00000003941
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat

Markers in Region
RH131781  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81940,361,687 - 40,362,015 (+)Marker Load Pipeline
mRatBN7.21923,456,860 - 23,457,188 (-)MAPPERmRatBN7.2
Rnor_6.01925,813,026 - 25,813,353NCBIRnor6.0
Rnor_5.01936,788,645 - 36,788,972UniSTSRnor5.0
RGSC_v3.41925,119,954 - 25,120,281UniSTSRGSC3.4
Celera1923,010,530 - 23,010,857UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
18 13 73 200 91 90 59 138 59 6 446 248 16 182 113 113 31 32 32

Sequence


Ensembl Acc Id: ENSRNOT00000003941   ⟹   ENSRNOP00000003941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1940,361,583 - 40,371,772 (-)Ensembl
mRatBN7.2 Ensembl1923,456,758 - 23,466,956 (-)Ensembl
Rnor_6.0 Ensembl1925,803,262 - 25,813,467 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098952   ⟹   ENSRNOP00000086901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1940,361,583 - 40,371,297 (-)Ensembl
mRatBN7.2 Ensembl1923,456,756 - 23,466,470 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111358   ⟹   ENSRNOP00000079419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1940,361,583 - 40,371,772 (-)Ensembl
mRatBN7.2 Ensembl1923,456,758 - 23,466,566 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000130211   ⟹   ENSRNOP00000101752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1940,361,583 - 40,374,622 (-)Ensembl
RefSeq Acc Id: NM_001013870   ⟹   NP_001013892
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81940,361,583 - 40,371,772 (-)NCBI
mRatBN7.21923,456,756 - 23,466,945 (-)NCBI
Rnor_6.01925,803,282 - 25,813,443 (+)NCBI
Rnor_5.01936,775,694 - 36,789,077 (+)NCBI
RGSC_v3.41925,119,864 - 25,130,026 (-)RGD
Celera1923,010,440 - 23,020,602 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255236   ⟹   XP_006255298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81940,361,583 - 40,374,971 (-)NCBI
mRatBN7.21923,456,756 - 23,471,577 (-)NCBI
Rnor_6.01925,798,263 - 25,813,458 (+)NCBI
Rnor_5.01936,775,694 - 36,789,077 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772365   ⟹   XP_008770587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81940,361,583 - 40,374,966 (-)NCBI
mRatBN7.21923,456,756 - 23,471,581 (-)NCBI
Rnor_6.01925,798,262 - 25,813,458 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772366   ⟹   XP_008770588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81940,361,583 - 40,374,965 (-)NCBI
mRatBN7.21923,456,756 - 23,471,579 (-)NCBI
Rnor_6.01925,798,262 - 25,813,458 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277830   ⟹   XP_063133900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81940,361,583 - 40,374,964 (-)NCBI
RefSeq Acc Id: NP_001013892   ⟸   NM_001013870
- UniProtKB: A0A8I5ZNF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255298   ⟸   XM_006255236
- Peptide Label: isoform X2
- UniProtKB: A0A140UHW6 (UniProtKB/TrEMBL),   A0A8I6A6S2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770587   ⟸   XM_008772365
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZNF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770588   ⟸   XM_008772366
- Peptide Label: isoform X2
- UniProtKB: A0A140UHW6 (UniProtKB/TrEMBL),   A0A8I6A6S2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003941   ⟸   ENSRNOT00000003941
Ensembl Acc Id: ENSRNOP00000079419   ⟸   ENSRNOT00000111358
Ensembl Acc Id: ENSRNOP00000086901   ⟸   ENSRNOT00000098952
RefSeq Acc Id: XP_063133900   ⟸   XM_063277830
- Peptide Label: isoform X2
- UniProtKB: A0A140UHW6 (UniProtKB/TrEMBL),   A0A8I6A6S2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101752   ⟸   ENSRNOT00000130211
Protein Domains
C3H1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A140UHW6-F1-model_v2 AlphaFold A0A140UHW6 1-638 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701021
Promoter ID:EPDNEW_R11545
Type:multiple initiation site
Name:Trmt1_1
Description:tRNA methyltransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01925,803,266 - 25,803,326EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305992 AgrOrtholog
BioCyc Gene G2FUF-6109 BioCyc
BioCyc Pathway PWY-6829 [tRNA methylation (yeast)] BioCyc
BioCyc Pathway Image PWY-6829 BioCyc
Ensembl Genes ENSRNOG00000002914 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003941 ENTREZGENE
  ENSRNOT00000003941.8 UniProtKB/TrEMBL
  ENSRNOT00000098952.2 UniProtKB/TrEMBL
  ENSRNOT00000111358.2 UniProtKB/TrEMBL
  ENSRNOT00000130211 ENTREZGENE
  ENSRNOT00000130211.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.56.70 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
  Zinc finger, CCCH-type UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132178 IMAGE-MGC_LOAD
InterPro SAM-dependent_MTases-like UniProtKB/TrEMBL
  TRM_MeTrfase UniProtKB/TrEMBL
  tRNA_met_Trm1_C UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
KEGG Report rno:288914 UniProtKB/TrEMBL
MGC_CLONE MGC:105886 IMAGE-MGC_LOAD
NCBI Gene 288914 ENTREZGENE
PANTHER TRM_mtfrase UniProtKB/TrEMBL
  TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE UniProtKB/TrEMBL
Pfam TRM UniProtKB/TrEMBL
  zf-CCCH UniProtKB/TrEMBL
PhenoGen Trmt1 PhenoGen
PROSITE SAM_MT216 UniProtKB/TrEMBL
  ZF_C3H1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002914 RatGTEx
SMART ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
  SSF90229 UniProtKB/TrEMBL
UniProt A0A140UHW6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZNF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6S2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LJJ9_RAT UniProtKB/TrEMBL
  A6IY79_RAT UniProtKB/TrEMBL
  A6IY80_RAT UniProtKB/TrEMBL
  A6IY81_RAT UniProtKB/TrEMBL
  A6IY82_RAT UniProtKB/TrEMBL
  A6IY83_RAT UniProtKB/TrEMBL
  A6IY84_RAT UniProtKB/TrEMBL
  Q5U4E4_RAT UniProtKB/TrEMBL
UniProt Secondary F1MAP8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-01 Trmt1  tRNA methyltransferase 1  Trmt1  tRNA methyltransferase 1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 Trmt1  tRNA methyltransferase 1 homolog (S. cerevisiae)  Trmt1  TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Trmt1  TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)  RGD1305992  similar to D8Ertd812e protein  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1305992  similar to D8Ertd812e protein  RGD1305992_predicted  similar to D8Ertd812e protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1305992_predicted  similar to D8Ertd812e protein (predicted)  LOC288914_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC288914_predicted  similar to D8Ertd812e protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL