Rin2 (Ras and Rab interactor 2) - Rat Genome Database

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Pathways
Gene: Rin2 (Ras and Rab interactor 2) Rattus norvegicus
Analyze
Symbol: Rin2
Name: Ras and Rab interactor 2
RGD ID: 1305873
Description: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in positive regulation of endothelial cell migration; positive regulation of endothelial cell-matrix adhesion via fibronectin; and positive regulation of vasculogenesis. Predicted to be located in cytoplasm. Predicted to be active in cytosol and endocytic vesicle. Orthologous to human RIN2 (Ras and Rab interactor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC311494
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83153,540,147 - 153,756,897 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3153,540,214 - 153,756,897 (+)EnsemblGRCr8
mRatBN7.23133,086,858 - 133,303,604 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,086,749 - 133,303,604 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3137,019,265 - 137,213,109 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03145,603,344 - 145,797,204 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03143,306,511 - 143,500,360 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03139,871,330 - 140,087,679 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3139,894,331 - 140,087,678 (+)Ensemblrn6Rnor6.0
Rnor_5.03146,294,631 - 146,510,343 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43134,307,538 - 134,503,915 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3131,974,768 - 132,168,991 (+)NCBICelera
RGSC_v3.13134,383,397 - 134,408,088 (+)NCBI
Cytogenetic Map3q41NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dibutyl phthalate  (EXP,ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
fluvastatin  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulfadimethoxine  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thiram  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22825554  


Genomics

Comparative Map Data
Rin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83153,540,147 - 153,756,897 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3153,540,214 - 153,756,897 (+)EnsemblGRCr8
mRatBN7.23133,086,858 - 133,303,604 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,086,749 - 133,303,604 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3137,019,265 - 137,213,109 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03145,603,344 - 145,797,204 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03143,306,511 - 143,500,360 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03139,871,330 - 140,087,679 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3139,894,331 - 140,087,678 (+)Ensemblrn6Rnor6.0
Rnor_5.03146,294,631 - 146,510,343 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43134,307,538 - 134,503,915 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3131,974,768 - 132,168,991 (+)NCBICelera
RGSC_v3.13134,383,397 - 134,408,088 (+)NCBI
Cytogenetic Map3q41NCBI
RIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382019,757,599 - 20,002,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2019,757,606 - 20,003,571 (+)Ensemblhg38GRCh38
GRCh372019,738,902 - 19,983,100 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362019,818,210 - 19,931,100 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342019,818,209 - 19,931,100NCBI
Celera2019,944,265 - 20,057,119 (+)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2019,829,693 - 19,944,819 (+)NCBIHuRef
CHM1_12019,867,581 - 19,983,477 (+)NCBICHM1_1
T2T-CHM13v2.02019,809,879 - 20,056,735 (+)NCBIT2T-CHM13v2.0
Rin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392145,613,647 - 145,729,536 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2145,517,135 - 145,729,536 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382145,771,727 - 145,887,616 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2145,675,215 - 145,887,616 (+)Ensemblmm10GRCm38
MGSCv372145,611,852 - 145,713,352 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362145,477,584 - 145,579,054 (+)NCBIMGSCv36mm8
Celera2147,020,636 - 147,123,470 (+)NCBICelera
Cytogenetic Map2G1NCBI
cM Map271.25NCBI
Rin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541527,984,449 - 28,133,214 (+)Ensembl
ChiLan1.0NW_00495541527,953,670 - 28,130,122 (+)NCBIChiLan1.0ChiLan1.0
RIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,644,990 - 20,890,589 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12020,683,986 - 20,887,426 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02019,716,071 - 19,960,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12019,683,013 - 19,925,764 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2019,811,284 - 19,924,256 (+)EnsemblpanPan2panpan1.1
RIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1243,345,221 - 3,563,716 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl243,343,087 - 3,563,772 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha243,373,428 - 3,591,885 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0243,753,523 - 3,972,256 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,751,358 - 3,944,655 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1243,349,198 - 3,567,538 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0243,452,567 - 3,671,029 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0243,730,425 - 3,949,191 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640151,946,228 - 152,171,904 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936485377,396 - 556,616 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936485377,562 - 556,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1727,807,244 - 28,058,135 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11727,941,333 - 28,058,150 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21732,441,716 - 32,456,755 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RIN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1248,768,647 - 49,020,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl248,905,779 - 49,021,368 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660783,553,322 - 3,805,798 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rin2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474120,441,972 - 20,536,464 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474120,338,306 - 20,537,500 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rin2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15125,397,527 - 125,524,191 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rin2
587 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:138
Interacting mature miRNAs:174
Transcripts:ENSRNOT00000064695
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
D3Rat217  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83153,746,295 - 153,746,477 (+)Marker Load Pipeline
mRatBN7.23133,293,002 - 133,293,184 (+)MAPPERmRatBN7.2
Rnor_6.03140,077,066 - 140,077,247NCBIRnor6.0
Rnor_5.03146,499,815 - 146,499,996UniSTSRnor5.0
RGSC_v3.43134,492,358 - 134,492,539UniSTSRGSC3.4
RGSC_v3.43134,491,977 - 134,492,553RGDRGSC3.4
RGSC_v3.13134,397,931 - 134,398,112RGD
RH 3.4 Map31171.1UniSTS
RH 3.4 Map31171.1RGD
SHRSP x BN Map364.1499UniSTS
SHRSP x BN Map364.1499RGD
Cytogenetic Map3q41UniSTS
D3Got99  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23133,271,252 - 133,271,441 (+)MAPPERmRatBN7.2
Rnor_6.03140,055,302 - 140,055,490NCBIRnor6.0
Rnor_5.03146,478,051 - 146,478,239UniSTSRnor5.0
RGSC_v3.43134,470,707 - 134,470,896RGDRGSC3.4
RGSC_v3.43134,470,708 - 134,470,896UniSTSRGSC3.4
Celera3132,136,692 - 132,136,880UniSTS
RGSC_v3.13134,376,281 - 134,376,469RGD
RH 3.4 Map31171.0RGD
RH 3.4 Map31171.0UniSTS
Cytogenetic Map3q41UniSTS
RH143773  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23133,303,127 - 133,303,347 (+)MAPPERmRatBN7.2
Rnor_6.03140,087,202 - 140,087,421NCBIRnor6.0
Rnor_5.03146,509,866 - 146,510,085UniSTSRnor5.0
RGSC_v3.43134,503,439 - 134,503,658UniSTSRGSC3.4
Celera3132,168,515 - 132,168,734UniSTS
RH 3.4 Map31109.3UniSTS
Cytogenetic Map3q41UniSTS
RH144685  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23133,298,726 - 133,298,876 (+)MAPPERmRatBN7.2
Rnor_6.03140,082,801 - 140,082,950NCBIRnor6.0
Rnor_5.03146,505,465 - 146,505,614UniSTSRnor5.0
RGSC_v3.43134,499,038 - 134,499,187UniSTSRGSC3.4
Celera3132,164,114 - 132,164,263UniSTS
RH 3.4 Map31171.4UniSTS
Cytogenetic Map3q41UniSTS
AU047563  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83153,666,647 - 153,666,906 (+)Marker Load Pipeline
mRatBN7.23133,213,343 - 133,213,602 (+)MAPPERmRatBN7.2
Rnor_6.03138,997,859 - 138,998,117NCBIRnor6.0
Rnor_6.03139,997,624 - 139,997,882NCBIRnor6.0
Rnor_5.03146,420,758 - 146,421,016UniSTSRnor5.0
Rnor_5.03145,426,991 - 145,427,249UniSTSRnor5.0
RGSC_v3.43134,411,913 - 134,412,171UniSTSRGSC3.4
Celera3132,078,615 - 132,078,873UniSTS
Cytogenetic Map3q41UniSTS
RH142025  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23133,165,321 - 133,165,517 (+)MAPPERmRatBN7.2
Rnor_6.03139,949,768 - 139,949,963NCBIRnor6.0
Rnor_5.03146,372,902 - 146,373,097UniSTSRnor5.0
RGSC_v3.43134,362,981 - 134,363,176UniSTSRGSC3.4
Celera3132,030,214 - 132,030,409UniSTS
RH 3.4 Map31171.1UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000064695   ⟹   ENSRNOP00000059327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3153,540,214 - 153,756,889 (+)Ensembl
mRatBN7.2 Ensembl3133,109,884 - 133,303,604 (+)Ensembl
Rnor_6.0 Ensembl3139,894,331 - 140,087,678 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086409   ⟹   ENSRNOP00000072197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3153,692,938 - 153,756,890 (+)Ensembl
mRatBN7.2 Ensembl3133,086,749 - 133,303,604 (+)Ensembl
Rnor_6.0 Ensembl3140,024,043 - 140,087,672 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096314   ⟹   ENSRNOP00000083107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3153,666,281 - 153,756,897 (+)Ensembl
mRatBN7.2 Ensembl3133,212,700 - 133,303,604 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155461   ⟹   ENSRNOP00000106504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3153,648,975 - 153,756,897 (+)Ensembl
RefSeq Acc Id: NM_001107786   ⟹   NP_001101256
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,563,185 - 153,756,896 (+)NCBI
mRatBN7.23133,109,884 - 133,303,604 (+)NCBI
Rnor_6.03139,894,331 - 140,087,678 (+)NCBI
Rnor_5.03146,294,631 - 146,510,343 (+)NCBI
RGSC_v3.43134,307,538 - 134,503,915 (+)RGD
Celera3131,974,768 - 132,168,991 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235142   ⟹   XP_006235204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,540,147 - 153,756,897 (+)NCBI
mRatBN7.23133,086,858 - 133,303,590 (+)NCBI
Rnor_6.03139,871,330 - 140,087,679 (+)NCBI
Rnor_5.03146,294,631 - 146,510,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235146   ⟹   XP_006235208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,647,927 - 153,756,897 (+)NCBI
mRatBN7.23133,194,626 - 133,303,591 (+)NCBI
Rnor_6.03139,978,530 - 140,085,995 (+)NCBI
Rnor_5.03146,294,631 - 146,510,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235148   ⟹   XP_006235210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,666,408 - 153,756,897 (+)NCBI
mRatBN7.23133,213,124 - 133,303,591 (+)NCBI
Rnor_6.03139,996,907 - 140,085,995 (+)NCBI
Rnor_5.03146,294,631 - 146,510,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235150   ⟹   XP_006235212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,692,736 - 153,756,897 (+)NCBI
mRatBN7.23133,239,437 - 133,303,591 (+)NCBI
Rnor_6.03140,023,324 - 140,085,995 (+)NCBI
Rnor_5.03146,294,631 - 146,510,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591763   ⟹   XP_017447252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,540,147 - 153,756,897 (+)NCBI
mRatBN7.23133,086,858 - 133,303,590 (+)NCBI
Rnor_6.03139,871,330 - 140,085,995 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591764   ⟹   XP_017447253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,540,147 - 153,756,897 (+)NCBI
mRatBN7.23133,086,858 - 133,303,590 (+)NCBI
Rnor_6.03139,871,330 - 140,087,665 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591766   ⟹   XP_017447255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,692,736 - 153,756,897 (+)NCBI
mRatBN7.23133,194,629 - 133,303,591 (+)NCBI
Rnor_6.03139,978,530 - 140,085,995 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105047   ⟹   XP_038960975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,700,022 - 153,756,897 (+)NCBI
mRatBN7.23133,246,723 - 133,303,591 (+)NCBI
RefSeq Acc Id: XM_063283805   ⟹   XP_063139875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,649,207 - 153,756,897 (+)NCBI
RefSeq Acc Id: XM_063283806   ⟹   XP_063139876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,540,147 - 153,756,897 (+)NCBI
RefSeq Acc Id: XM_063283807   ⟹   XP_063139877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,614,668 - 153,756,897 (+)NCBI
RefSeq Acc Id: XM_063283808   ⟹   XP_063139878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83153,692,736 - 153,756,897 (+)NCBI
RefSeq Acc Id: NP_001101256   ⟸   NM_001107786
- UniProtKB: D4A6C4 (UniProtKB/TrEMBL),   A6K774 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235204   ⟸   XM_006235142
- Peptide Label: isoform X1
- UniProtKB: D4A6C4 (UniProtKB/TrEMBL),   A6K774 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235208   ⟸   XM_006235146
- Peptide Label: isoform X1
- UniProtKB: D4A6C4 (UniProtKB/TrEMBL),   A6K774 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235210   ⟸   XM_006235148
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235212   ⟸   XM_006235150
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K2D2 (UniProtKB/TrEMBL),   A6K775 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447253   ⟸   XM_017591764
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017447252   ⟸   XM_017591763
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017447255   ⟸   XM_017591766
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSRNOP00000072197   ⟸   ENSRNOT00000086409
Ensembl Acc Id: ENSRNOP00000059327   ⟸   ENSRNOT00000064695
RefSeq Acc Id: XP_038960975   ⟸   XM_039105047
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000083107   ⟸   ENSRNOT00000096314
RefSeq Acc Id: XP_063139876   ⟸   XM_063283806
- Peptide Label: isoform X1
- UniProtKB: A6K774 (UniProtKB/TrEMBL),   D4A6C4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139877   ⟸   XM_063283807
- Peptide Label: isoform X1
- UniProtKB: A6K774 (UniProtKB/TrEMBL),   D4A6C4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139875   ⟸   XM_063283805
- Peptide Label: isoform X1
- UniProtKB: A6K774 (UniProtKB/TrEMBL),   D4A6C4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139878   ⟸   XM_063283808
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K2D2 (UniProtKB/TrEMBL),   A6K775 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106504   ⟸   ENSRNOT00000155461
Protein Domains
Ras-associating   SH2   VPS9

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A6C4-F1-model_v2 AlphaFold D4A6C4 1-902 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692489
Promoter ID:EPDNEW_R3014
Type:multiple initiation site
Name:Rin2_1
Description:Ras and Rab interactor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03139,980,565 - 139,980,625EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305873 AgrOrtholog
BioCyc Gene G2FUF-47582 BioCyc
Ensembl Genes ENSRNOG00000010131 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064695 ENTREZGENE
  ENSRNOT00000064695.4 UniProtKB/TrEMBL
  ENSRNOT00000086409 ENTREZGENE
  ENSRNOT00000086409.3 UniProtKB/TrEMBL
  ENSRNOT00000096314 ENTREZGENE
  ENSRNOT00000096314.2 UniProtKB/TrEMBL
  ENSRNOT00000155461 ENTREZGENE
  ENSRNOT00000155461.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.80 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro Ras-assoc UniProtKB/TrEMBL
  RIN2_SH2 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
  Vps9-like UniProtKB/TrEMBL
  VPS9_dom_sf UniProtKB/TrEMBL
KEGG Report rno:311494 UniProtKB/TrEMBL
NCBI Gene 311494 ENTREZGENE
PANTHER PTHR23101 UniProtKB/TrEMBL
  RAS AND RAB INTERACTOR 2 UniProtKB/TrEMBL
Pfam PF00788 UniProtKB/TrEMBL
  RIN1 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
PhenoGen Rin2 PhenoGen
PROSITE PS50200 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010131 RatGTEx
SMART SH2 UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
Superfamily-SCOP SSF109993 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A0G2K2D2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZUT7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LNS3_RAT UniProtKB/TrEMBL
  A6K774 ENTREZGENE, UniProtKB/TrEMBL
  A6K775 ENTREZGENE, UniProtKB/TrEMBL
  D4A6C4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rin2  Ras and Rab interactor 2   Rin2_predicted  Ras and Rab interactor 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rin2_predicted  Ras and Rab interactor 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED