Fbxl7 (F-box and leucine-rich repeat protein 7) - Rat Genome Database

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Gene: Fbxl7 (F-box and leucine-rich repeat protein 7) Rattus norvegicus
Analyze
Symbol: Fbxl7
Name: F-box and leucine-rich repeat protein 7
RGD ID: 1305813
Description: Predicted to be involved in G2/M transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and protein polyubiquitination. Predicted to be located in centrosome. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL7 (F-box and leucine rich repeat protein 7); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: F-box/LRR-repeat protein 7; LOC361907
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8278,870,236 - 79,239,697 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl278,871,287 - 79,239,697 (-)EnsemblGRCr8
mRatBN7.2277,139,775 - 77,509,223 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl277,140,826 - 77,509,223 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx284,270,635 - 84,639,171 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0282,392,357 - 82,760,863 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0277,398,724 - 77,767,177 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0279,067,907 - 79,439,987 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl279,067,915 - 79,078,258 (-)Ensemblrn6Rnor6.0
Rnor_5.0298,741,811 - 99,111,076 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4278,232,361 - 78,610,165 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera272,829,001 - 73,197,580 (-)NCBICelera
RGSC_v3.1278,178,856 - 78,649,371 (-)NCBI
Cytogenetic Map2q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxyethanol  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
indometacin  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA,ISO)
SCF ubiquitin ligase complex  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19028597   PMID:22306998   PMID:25778398   PMID:28218735  


Genomics

Comparative Map Data
Fbxl7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8278,870,236 - 79,239,697 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl278,871,287 - 79,239,697 (-)EnsemblGRCr8
mRatBN7.2277,139,775 - 77,509,223 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl277,140,826 - 77,509,223 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx284,270,635 - 84,639,171 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0282,392,357 - 82,760,863 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0277,398,724 - 77,767,177 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0279,067,907 - 79,439,987 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl279,067,915 - 79,078,258 (-)Ensemblrn6Rnor6.0
Rnor_5.0298,741,811 - 99,111,076 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4278,232,361 - 78,610,165 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera272,829,001 - 73,197,580 (-)NCBICelera
RGSC_v3.1278,178,856 - 78,649,371 (-)NCBI
Cytogenetic Map2q22NCBI
FBXL7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38515,500,180 - 15,939,793 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl515,500,180 - 15,939,795 (+)Ensemblhg38GRCh38
GRCh37515,500,289 - 15,939,902 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36515,553,305 - 15,992,900 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34515,553,304 - 15,992,900NCBI
Celera515,523,976 - 15,963,562 (+)NCBICelera
Cytogenetic Map5p15.1NCBI
HuRef515,473,183 - 15,912,276 (+)NCBIHuRef
CHM1_1515,500,175 - 15,939,783 (+)NCBICHM1_1
T2T-CHM13v2.0515,439,591 - 15,879,159 (+)NCBIT2T-CHM13v2.0
Fbxl7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391526,540,540 - 26,895,650 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1526,540,545 - 26,895,666 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381526,540,454 - 26,895,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1526,540,459 - 26,895,580 (-)Ensemblmm10GRCm38
MGSCv371526,470,214 - 26,825,319 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361526,485,184 - 26,840,289 (-)NCBIMGSCv36mm8
Celera1527,297,939 - 27,655,658 (-)NCBICelera
Cytogenetic Map15B1NCBI
cM Map159.87NCBI
Fbxl7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554264,659,968 - 5,041,475 (+)Ensembl
ChiLan1.0NW_0049554264,659,787 - 5,044,074 (+)NCBIChiLan1.0ChiLan1.0
FBXL7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2415,734,425 - 16,167,529 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1513,888,259 - 14,321,140 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0515,804,479 - 16,237,326 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1515,643,666 - 16,075,623 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl515,643,846 - 16,075,623 (+)EnsemblpanPan2panpan1.1
FBXL7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1487,348,187 - 87,637,517 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl487,350,321 - 87,612,238 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha486,867,252 - 87,219,613 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0487,980,951 - 88,269,112 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl487,983,060 - 88,424,855 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1487,502,813 - 87,852,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0487,745,973 - 88,095,924 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0488,597,528 - 88,949,898 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fbxl7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213232,011,696 - 232,380,215 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936665607,805 - 973,462 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936665605,225 - 973,735 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl164,784,726 - 5,194,189 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1164,784,452 - 5,194,193 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2165,583,939 - 5,594,475 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXL7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1415,191,309 - 15,621,160 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606412,850,671 - 13,280,473 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxl7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475112,432,207 - 12,828,946 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475112,431,974 - 12,831,463 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fbxl7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13153,931,302 - 154,283,178 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fbxl7
3160 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:33
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000031170
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)261556902106556902Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)261051883104684275Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)261051541105724065Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)278269809104744824Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)261051541105724065Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)260861391105861391Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat

Markers in Region
D2Got36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2277,503,119 - 77,503,363 (+)MAPPERmRatBN7.2
Rnor_6.0279,433,884 - 79,434,127NCBIRnor6.0
Rnor_5.0299,104,973 - 99,105,216UniSTSRnor5.0
RGSC_v3.4278,604,061 - 78,604,305RGDRGSC3.4
RGSC_v3.4278,604,062 - 78,604,305UniSTSRGSC3.4
Celera273,191,475 - 73,191,720UniSTS
RGSC_v3.1278,549,023 - 78,549,267RGD
RH 3.4 Map2398.0UniSTS
RH 3.4 Map2398.0RGD
RH 2.0 Map2395.0RGD
Cytogenetic Map2q22UniSTS
D2Got38  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2277,345,173 - 77,345,300 (+)MAPPERmRatBN7.2
Rnor_6.0279,276,178 - 79,276,304NCBIRnor6.0
Rnor_5.0298,947,455 - 98,947,581UniSTSRnor5.0
RGSC_v3.4278,439,521 - 78,439,647UniSTSRGSC3.4
Celera273,033,399 - 73,033,525UniSTS
RGSC_v3.1278,384,484 - 78,384,609RGD
RH 3.4 Map2397.2UniSTS
RH 3.4 Map2397.2RGD
RH 2.0 Map2396.3RGD
Cytogenetic Map2q22UniSTS
BF397347  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2277,305,012 - 77,305,256 (+)MAPPERmRatBN7.2
Rnor_6.0279,233,630 - 79,233,873NCBIRnor6.0
Rnor_5.0298,907,413 - 98,907,656UniSTSRnor5.0
RGSC_v3.4278,399,607 - 78,399,850UniSTSRGSC3.4
Celera272,993,342 - 72,993,585UniSTS
RH 3.4 Map461.3UniSTS
Cytogenetic Map2q22UniSTS
BE117721  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2277,283,156 - 77,283,341 (+)MAPPERmRatBN7.2
Rnor_6.0279,211,774 - 79,211,958NCBIRnor6.0
Rnor_5.0298,885,557 - 98,885,741UniSTSRnor5.0
RGSC_v3.4278,377,751 - 78,377,935UniSTSRGSC3.4
Celera272,971,502 - 72,971,686UniSTS
RH 3.4 Map2382.8UniSTS
Cytogenetic Map2q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 13 68 160 91 90 59 31 59 6 305 133 12 143 89 93 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000031170   ⟹   ENSRNOP00000033571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl278,871,287 - 79,239,697 (-)Ensembl
mRatBN7.2 Ensembl277,140,826 - 77,509,223 (-)Ensembl
Rnor_6.0 Ensembl279,067,915 - 79,078,258 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126943   ⟹   ENSRNOP00000111233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl278,871,287 - 79,175,809 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156900   ⟹   ENSRNOP00000104729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl278,871,287 - 78,890,564 (-)Ensembl
RefSeq Acc Id: NM_001108545   ⟹   NP_001102015
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8278,871,287 - 79,239,697 (-)NCBI
mRatBN7.2277,140,826 - 77,509,223 (-)NCBI
Rnor_6.0279,068,958 - 79,439,987 (-)NCBI
Rnor_5.0298,741,811 - 99,111,076 (-)NCBI
RGSC_v3.4278,232,361 - 78,610,165 (-)RGD
Celera272,829,001 - 73,197,580 (-)RGD
Sequence:
RefSeq Acc Id: XM_039102576   ⟹   XP_038958504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8278,870,236 - 79,217,880 (-)NCBI
mRatBN7.2277,139,775 - 77,487,406 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102015 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958504 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL82624 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033571
  ENSRNOP00000033571.7
  ENSRNOP00000104729.1
  ENSRNOP00000111233.1
RefSeq Acc Id: NP_001102015   ⟸   NM_001108545
- UniProtKB: F1M6W6 (UniProtKB/TrEMBL),   A6JMX5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033571   ⟸   ENSRNOT00000031170
RefSeq Acc Id: XP_038958504   ⟸   XM_039102576
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000111233   ⟸   ENSRNOT00000126943
Ensembl Acc Id: ENSRNOP00000104729   ⟸   ENSRNOT00000156900
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M6W6-F1-model_v2 AlphaFold F1M6W6 1-444 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305813 AgrOrtholog
BioCyc Gene G2FUF-53929 BioCyc
Ensembl Genes ENSRNOG00000024433 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031170 ENTREZGENE
  ENSRNOT00000031170.8 UniProtKB/TrEMBL
  ENSRNOT00000126943.1 UniProtKB/TrEMBL
  ENSRNOT00000156900.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro F-box_dom_cyclin-like UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_Cys-con_subtyp UniProtKB/TrEMBL
KEGG Report rno:361907 UniProtKB/TrEMBL
NCBI Gene 361907 ENTREZGENE
PANTHER F-BOX_LRR-REPEAT PROTEIN 7 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  LRR_6 UniProtKB/TrEMBL
PhenoGen Fbxl7 PhenoGen
PROSITE FBOX UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024433 RatGTEx
SMART FBOX UniProtKB/TrEMBL
  LRR_CC UniProtKB/TrEMBL
Superfamily-SCOP F-box_dom_Skp2-like UniProtKB/TrEMBL
  RNI-like UniProtKB/TrEMBL
UniProt A0ABK0LIQ0_RAT UniProtKB/TrEMBL
  A0ABK0LXX1_RAT UniProtKB/TrEMBL
  A6JMX5 ENTREZGENE, UniProtKB/TrEMBL
  F1M6W6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Fbxl7  F-box and leucine-rich repeat protein 7   Fbxl7_predicted  F-box and leucine-rich repeat protein 7 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fbxl7_predicted  F-box and leucine-rich repeat protein 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED