Dusp2 (dual specificity phosphatase 2) - Rat Genome Database

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Gene: Dusp2 (dual specificity phosphatase 2) Rattus norvegicus
Analyze
Symbol: Dusp2
Name: dual specificity phosphatase 2
RGD ID: 1305804
Description: Predicted to enable mitogen-activated protein kinase binding activity and phosphoprotein phosphatase activity. Predicted to be involved in endoderm formation; negative regulation of MAPK cascade; and signal transduction. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human DUSP2 (dual specificity phosphatase 2); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dual specificity protein phosphatase 2; LOC311406
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,009,636 - 135,011,821 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3135,009,590 - 135,011,809 (+)EnsemblGRCr8
mRatBN7.23114,556,325 - 114,558,510 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,556,325 - 114,558,499 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3118,445,557 - 118,447,742 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,041,118 - 127,043,303 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,701,487 - 124,703,672 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,776,925 - 119,779,110 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,776,925 - 119,779,099 (+)Ensemblrn6Rnor6.0
Rnor_5.03126,303,199 - 126,305,384 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43114,838,605 - 114,840,790 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3113,395,499 - 113,397,684 (+)NCBICelera
RGSC_v3.13114,744,177 - 114,746,352 (+)NCBI
Cytogenetic Map3q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butoxyethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-amanitin  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
choline  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
D-glucose  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dieldrin  (ISO)
dimethylarsinic acid  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
etoposide  (ISO)
ferroheme b  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glyphosate  (ISO)
GSK-J4  (ISO)
heme b  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
L-methionine  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
melphalan  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylarsonic acid  (ISO)
methylisothiazolinone  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-Nitrosopyrrolidine  (ISO)
okadaic acid  (ISO)
omega-6 fatty acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
tebuconazole  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16288922   PMID:24851838  


Genomics

Comparative Map Data
Dusp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,009,636 - 135,011,821 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3135,009,590 - 135,011,809 (+)EnsemblGRCr8
mRatBN7.23114,556,325 - 114,558,510 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,556,325 - 114,558,499 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3118,445,557 - 118,447,742 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,041,118 - 127,043,303 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,701,487 - 124,703,672 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,776,925 - 119,779,110 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,776,925 - 119,779,099 (+)Ensemblrn6Rnor6.0
Rnor_5.03126,303,199 - 126,305,384 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43114,838,605 - 114,840,790 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3113,395,499 - 113,397,684 (+)NCBICelera
RGSC_v3.13114,744,177 - 114,746,352 (+)NCBI
Cytogenetic Map3q36NCBI
DUSP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38296,143,169 - 96,145,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl296,143,166 - 96,145,440 (-)Ensemblhg38GRCh38
GRCh37296,808,908 - 96,811,179 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,172,638 - 96,174,906 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34296,230,790 - 96,233,053NCBI
Celera291,249,715 - 91,251,986 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef290,770,185 - 90,772,456 (-)NCBIHuRef
CHM1_1296,813,182 - 96,815,453 (-)NCBICHM1_1
T2T-CHM13v2.0296,649,773 - 96,656,541 (-)NCBIT2T-CHM13v2.0
Dusp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,178,079 - 127,180,297 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,178,079 - 127,180,296 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382127,336,159 - 127,338,377 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,336,159 - 127,338,376 (+)Ensemblmm10GRCm38
MGSCv372127,161,895 - 127,164,113 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362128,316,151 - 128,318,369 (+)NCBIMGSCv36mm8
MGSCv362127,027,600 - 127,029,818 (+)NCBIMGSCv36mm8
Cytogenetic Map2F1NCBI
cM Map261.93NCBI
Dusp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,735,871 - 3,737,568 (-)Ensembl
ChiLan1.0NW_0049554703,735,224 - 3,737,667 (-)NCBIChiLan1.0ChiLan1.0
DUSP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21232,163,053 - 32,165,336 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A32,165,812 - 32,168,095 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A103,169,874 - 103,172,158 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A97,068,210 - 97,070,505 (-)NCBIPanPan1.1PanPan1.1panPan2
DUSP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11734,586,635 - 34,589,076 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,586,716 - 34,588,453 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1734,356,392 - 34,358,603 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01735,357,957 - 35,360,188 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1735,357,957 - 35,360,187 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11734,487,278 - 34,489,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01734,555,607 - 34,557,809 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01734,762,735 - 34,764,961 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dusp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,018,673 - 83,020,329 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744271,469 - 273,326 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936744271,619 - 273,272 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUSP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,052,458 - 47,054,810 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1347,052,443 - 47,054,816 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,187,416 - 49,194,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DUSP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114580,686 - 582,939 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14580,694 - 582,910 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041168,001,720 - 168,004,581 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dusp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,258,356 - 2,260,455 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247492,258,317 - 2,260,542 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dusp2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15106,119,404 - 106,121,724 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dusp2
30 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:73
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000018549
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3122654702136118980Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)3125814931139636791Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
RH133485  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23114,558,271 - 114,558,451 (+)MAPPERmRatBN7.2
Rnor_6.03119,778,872 - 119,779,051NCBIRnor6.0
Rnor_5.03126,305,146 - 126,305,325UniSTSRnor5.0
RGSC_v3.43114,840,552 - 114,840,731UniSTSRGSC3.4
Celera3113,397,446 - 113,397,625UniSTS
RH 3.4 Map3997.7UniSTS
Cytogenetic Map3q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018549   ⟹   ENSRNOP00000018549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3135,009,590 - 135,011,809 (+)Ensembl
mRatBN7.2 Ensembl3114,556,325 - 114,558,499 (+)Ensembl
Rnor_6.0 Ensembl3119,776,925 - 119,779,099 (+)Ensembl
RefSeq Acc Id: NM_001012089   ⟹   NP_001012089
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83135,009,636 - 135,011,821 (+)NCBI
mRatBN7.23114,556,325 - 114,558,510 (+)NCBI
Rnor_6.03119,776,925 - 119,779,110 (+)NCBI
Rnor_5.03126,303,199 - 126,305,384 (+)NCBI
RGSC_v3.43114,838,605 - 114,840,790 (+)RGD
Celera3113,395,499 - 113,397,684 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001012089 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88205 (Get FASTA)   NCBI Sequence Viewer  
  EDL80113 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018549
  ENSRNOP00000018549.6
RefSeq Acc Id: NP_001012089   ⟸   NM_001012089
- UniProtKB: Q5M863 (UniProtKB/TrEMBL),   A6HQ12 (UniProtKB/TrEMBL),   F7F375 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018549   ⟸   ENSRNOT00000018549
Protein Domains
Rhodanese   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M863-F1-model_v2 AlphaFold Q5M863 1-318 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692403
Promoter ID:EPDNEW_R2928
Type:single initiation site
Name:Dusp2_1
Description:dual specificity phosphatase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03119,776,911 - 119,776,971EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305804 AgrOrtholog
BioCyc Gene G2FUF-47995 BioCyc
Ensembl Genes ENSRNOG00000013862 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018549 ENTREZGENE
  ENSRNOT00000018549.7 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7380627 IMAGE-MGC_LOAD
InterPro Dual-sp/Tyr_phosphatase UniProtKB/TrEMBL
  Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  Dual-sp_phosphatase_subgr_cat UniProtKB/TrEMBL
  MAPK_phosph UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Rhodanese-like UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
KEGG Report rno:311406 UniProtKB/TrEMBL
MGC_CLONE MGC:108907 IMAGE-MGC_LOAD
NCBI Gene 311406 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN PHOSPHATASE UniProtKB/TrEMBL
  DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 UniProtKB/TrEMBL
Pfam DSPc UniProtKB/TrEMBL
  Rhodanese UniProtKB/TrEMBL
PhenoGen Dusp2 PhenoGen
PIRSF MAPK_Ptase UniProtKB/TrEMBL
PRINTS ADSPHPHTASE UniProtKB/TrEMBL
  MAPKPHPHTASE UniProtKB/TrEMBL
PROSITE RHODANESE_3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013862 RatGTEx
SMART DSPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  RHOD UniProtKB/TrEMBL
Superfamily-SCOP Rhodanese-like UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0ABZ3NNB7_RAT UniProtKB/TrEMBL
  A6HQ12 ENTREZGENE, UniProtKB/TrEMBL
  F7F375 ENTREZGENE, UniProtKB/TrEMBL
  Q5M863 ENTREZGENE
UniProt Secondary Q5M863 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Dusp2  dual specificity phosphatase 2  Dusp2_predicted  dual specificity phosphatase 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dusp2_predicted  dual specificity phosphatase 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED