Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nudt21 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Nudt21 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NUDT21 mRNA | CTD | PMID:22206623 | Nudt21 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of NUDT21 mRNA | CTD | PMID:17555576 | Nudt21 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Nudt21 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUDT21 mRNA | CTD | PMID:17942748 | Nudt21 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of NUDT21 mRNA | CTD | PMID:17942748 | Nudt21 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether affects the expression of NUDT21 mRNA | CTD | PMID:30294300 | Nudt21 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUDT21 mRNA | CTD | PMID:21570461 | Nudt21 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUDT21 mRNA | CTD | PMID:33387578 | Nudt21 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Nudt21 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUDT21 mRNA | CTD | PMID:17942748 | Nudt21 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUDT21 mRNA | CTD | PMID:26290441 | Nudt21 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUDT21 mRNA | CTD | PMID:22574217 | Nudt21 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | 2,4,6-tribromophenol results in decreased expression of NUDT21 mRNA | CTD | PMID:31675489 | Nudt21 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NUDT21 mRNA | CTD | PMID:30851411 | Nudt21 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of NUDT21 protein | CTD | PMID:31675489 | Nudt21 | Rat | 3-methylcholanthrene | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Methylcholanthrene results in increased expression of NUDT21 mRNA | CTD | PMID:20713471 | Nudt21 | Rat | all-trans-retinoic acid | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NUDT21 mRNA | CTD | PMID:15498508|PMID:33167477 | Nudt21 | Rat | aristolochic acid A | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NUDT21 mRNA | CTD | PMID:33212167 | Nudt21 | Rat | arsane | increases ubiquitination | ISO | NUDT21 (Homo sapiens) | 6480464 | Arsenic results in increased ubiquitination of NUDT21 protein | CTD | PMID:35994080 | Nudt21 | Rat | arsenic atom | increases ubiquitination | ISO | NUDT21 (Homo sapiens) | 6480464 | Arsenic results in increased ubiquitination of NUDT21 protein | CTD | PMID:35994080 | Nudt21 | Rat | arsenite(3-) | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to NUDT21 protein]; arsenite promotes the reaction [G3BP1 more ... | CTD | PMID:32406909 | Nudt21 | Rat | benzo[a]pyrene | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NUDT21 mRNA | CTD | PMID:22228805 | Nudt21 | Rat | benzo[a]pyrene | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of NUDT21 mRNA | CTD | PMID:21632981 | Nudt21 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NUDT21 mRNA | CTD | PMID:26238291 | Nudt21 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of NUDT21 mRNA | CTD | PMID:33754040 | Nudt21 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NUDT21 mRNA | CTD | PMID:25181051 | Nudt21 | Rat | bisphenol A | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of NUDT21 protein | CTD | PMID:34186270 | Nudt21 | Rat | bisphenol A | affects expression | ISO | NUDT21 (Homo sapiens) | 6480464 | bisphenol A affects the expression of NUDT21 mRNA | CTD | PMID:30903817 | Nudt21 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NUDT21 mRNA | CTD | PMID:30816183 | Nudt21 | Rat | bisphenol AF | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of NUDT21 protein | CTD | PMID:34186270 | Nudt21 | Rat | Bisphenol B | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of NUDT21 protein | CTD | PMID:34186270 | Nudt21 | Rat | bisphenol F | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of NUDT21 protein | CTD | PMID:34186270 | Nudt21 | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of NUDT21 protein | CTD | PMID:28903499 | Nudt21 | Rat | cadmium atom | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NUDT21 more ... | CTD | PMID:35301059 | Nudt21 | Rat | cadmium dichloride | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NUDT21 more ... | CTD | PMID:35301059 | Nudt21 | Rat | cadmium dichloride | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NUDT21 mRNA | CTD | PMID:38174414 | Nudt21 | Rat | carbon nanotube | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of NUDT21 mRNA | CTD | PMID:25554681 | Nudt21 | Rat | cisplatin | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NUDT21 mRNA | CTD | PMID:27594783 | Nudt21 | Rat | copper atom | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of NUDT21 mRNA | CTD | PMID:20971185 | Nudt21 | Rat | copper(0) | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of NUDT21 mRNA | CTD | PMID:20971185 | Nudt21 | Rat | coumestrol | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of NUDT21 mRNA | CTD | PMID:19167446 | Nudt21 | Rat | cyclosporin A | decreases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of NUDT21 mRNA | CTD | PMID:19770486 | Nudt21 | Rat | cyclosporin A | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NUDT21 mRNA | CTD | PMID:25562108 | Nudt21 | Rat | DDE | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of NUDT21 mRNA | CTD | PMID:38568856 | Nudt21 | Rat | decabromodiphenyl ether | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of NUDT21 protein | CTD | PMID:31675489 | Nudt21 | Rat | dexamethasone | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of NUDT21 mRNA | CTD | PMID:17998272 | Nudt21 | Rat | Dibutyl phosphate | affects expression | ISO | NUDT21 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NUDT21 mRNA | CTD | PMID:37042841 | Nudt21 | Rat | dorsomorphin | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Nudt21 | Rat | ethanol | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | Ethanol affects the expression of NUDT21 mRNA | CTD | PMID:30319688 | Nudt21 | Rat | folic acid | multiple interactions | ISO | Nudt21 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NUDT21 mRNA | CTD | PMID:22206623 | Nudt21 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of NUDT21 mRNA | CTD | PMID:22061828 | Nudt21 | Rat | isotretinoin | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of NUDT21 mRNA | CTD | PMID:20436886 | Nudt21 | Rat | ivermectin | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NUDT21 protein | CTD | PMID:32959892 | Nudt21 | Rat | lipopolysaccharide | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of NUDT21 mRNA | CTD | PMID:35877022 | Nudt21 | Rat | methidathion | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | methidathion affects the expression of NUDT21 mRNA | CTD | PMID:34813904 | Nudt21 | Rat | methotrexate | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | Methotrexate affects the expression of NUDT21 mRNA | CTD | PMID:18502557 | Nudt21 | Rat | methylmercury chloride | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of NUDT21 mRNA | CTD | PMID:28001369 | Nudt21 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of NUDT21 protein | CTD | PMID:24806433 | Nudt21 | Rat | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of NUDT21 mRNA | CTD | PMID:22124623 | Nudt21 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NUDT21 mRNA | CTD | PMID:25729387 | Nudt21 | Rat | paracetamol | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NUDT21 mRNA | CTD | PMID:17562736 | Nudt21 | Rat | paracetamol | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NUDT21 mRNA | CTD | PMID:21420995|PMID:26497421 | Nudt21 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Nudt21 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of NUDT21 mRNA | CTD | PMID:36331819 | Nudt21 | Rat | pirinixic acid | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NUDT21 mRNA | CTD | PMID:23811191 | Nudt21 | Rat | piroxicam | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Piroxicam results in decreased expression of NUDT21 mRNA | CTD | PMID:21858171 | Nudt21 | Rat | rac-lactic acid | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NUDT21 mRNA | CTD | PMID:30851411 | Nudt21 | Rat | resveratrol | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of NUDT21 mRNA | CTD | PMID:23557933 | Nudt21 | Rat | rotenone | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Rotenone results in increased expression of NUDT21 mRNA | CTD | PMID:33512557 | Nudt21 | Rat | SB 431542 | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Nudt21 | Rat | sodium arsenite | increases activity | ISO | NUDT21 (Homo sapiens) | 6480464 | sodium arsenite results in increased activity of NUDT21 protein | CTD | PMID:30528433 | Nudt21 | Rat | tamibarotene | affects expression | ISO | NUDT21 (Homo sapiens) | 6480464 | tamibarotene affects the expression of NUDT21 mRNA | CTD | PMID:15498508 | Nudt21 | Rat | tamoxifen | affects expression | ISO | Nudt21 (Mus musculus) | 6480464 | Tamoxifen affects the expression of NUDT21 mRNA | CTD | PMID:17555576 | Nudt21 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of NUDT21 mRNA | CTD | PMID:15336504 | Nudt21 | Rat | tert-butyl hydroperoxide | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of NUDT21 mRNA | CTD | PMID:15336504 | Nudt21 | Rat | thapsigargin | decreases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Thapsigargin results in decreased expression of NUDT21 protein | CTD | PMID:24648495 | Nudt21 | Rat | titanium dioxide | decreases methylation | ISO | Nudt21 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of NUDT21 gene | CTD | PMID:35295148 | Nudt21 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NUDT21 mRNA | CTD | PMID:25729387 | Nudt21 | Rat | trichostatin A | multiple interactions | ISO | NUDT21 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Nudt21 | Rat | trimellitic anhydride | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of NUDT21 mRNA | CTD | PMID:19042947 | Nudt21 | Rat | triphenyl phosphate | affects expression | ISO | NUDT21 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of NUDT21 mRNA | CTD | PMID:37042841 | Nudt21 | Rat | troglitazone | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | troglitazone results in decreased expression of NUDT21 mRNA | CTD | PMID:19140230 | Nudt21 | Rat | troglitazone | decreases expression | ISO | Nudt21 (Mus musculus) | 6480464 | troglitazone results in decreased expression of NUDT21 mRNA | CTD | PMID:28973697 | Nudt21 | Rat | tungsten | increases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Tungsten results in increased expression of NUDT21 mRNA | CTD | PMID:30912803 | Nudt21 | Rat | valproic acid | decreases methylation | ISO | NUDT21 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of NUDT21 gene | CTD | PMID:29154799 | Nudt21 | Rat | valproic acid | increases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NUDT21 mRNA; Valproic Acid results in increased expression more ... | CTD | PMID:29501571 | Nudt21 | Rat | valproic acid | increases methylation | ISO | NUDT21 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NUDT21 gene | CTD | PMID:29501571 | Nudt21 | Rat | valproic acid | affects expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NUDT21 mRNA | CTD | PMID:25979313 | Nudt21 | Rat | valproic acid | decreases expression | ISO | NUDT21 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NUDT21 mRNA | CTD | PMID:23179753 | Nudt21 | Rat | vancomycin | decreases expression | ISO | Nudt21 (Mus musculus) | 6480464 | Vancomycin results in decreased expression of NUDT21 mRNA | CTD | PMID:18930951 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















