Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gcc2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of GCC2 mRNA | CTD | PMID:22206623 | Gcc2 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of GCC2 mRNA | CTD | PMID:26496021 | Gcc2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Gcc2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GCC2 mRNA | CTD | PMID:21570461 | Gcc2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GCC2 mRNA | CTD | PMID:33387578 | Gcc2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GCC2 mRNA | CTD | PMID:32109520 | Gcc2 | Rat | acrolein | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268 | Gcc2 | Rat | aflatoxin B1 | increases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of GCC2 mRNA | CTD | PMID:19770486 | Gcc2 | Rat | all-trans-retinoic acid | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of GCC2 mRNA | CTD | PMID:23724009 | Gcc2 | Rat | alpha-pinene | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268 | Gcc2 | Rat | arsenous acid | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of GCC2 mRNA | CTD | PMID:22521957 | Gcc2 | Rat | benzo[a]pyrene | increases methylation | ISO | GCC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of GCC2 3' UTR | CTD | PMID:27901495 | Gcc2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GCC2 mRNA | CTD | PMID:19150397 | Gcc2 | Rat | benzo[b]fluoranthene | increases expression | ISO | Gcc2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of GCC2 mRNA | CTD | PMID:26377693 | Gcc2 | Rat | beta-lapachone | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of GCC2 mRNA | CTD | PMID:38218311 | Gcc2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of GCC2 mRNA | CTD | PMID:33754040 | Gcc2 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of GCC2 mRNA; [bisphenol A co-treated more ... | CTD | PMID:26496021|PMID:31129395 | Gcc2 | Rat | bisphenol A | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of GCC2 mRNA | CTD | PMID:33221593 | Gcc2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GCC2 mRNA | CTD | PMID:33296240 | Gcc2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GCC2 mRNA | CTD | PMID:30816183|PMID:32528016|PMID:34947998 | Gcc2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of GCC2 mRNA | CTD | PMID:25181051 | Gcc2 | Rat | bisphenol F | increases expression | ISO | Gcc2 (Mus musculus) | 6480464 | bisphenol F results in increased expression of GCC2 mRNA | CTD | PMID:38685157 | Gcc2 | Rat | cadmium atom | multiple interactions | ISO | Gcc2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GCC2 more ... | CTD | PMID:37236586 | Gcc2 | Rat | cadmium dichloride | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of GCC2 mRNA | CTD | PMID:24982889 | Gcc2 | Rat | cadmium dichloride | multiple interactions | ISO | Gcc2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GCC2 more ... | CTD | PMID:37236586 | Gcc2 | Rat | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of GCC2 mRNA | CTD | PMID:23125180 | Gcc2 | Rat | chlorpyrifos | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of GCC2 mRNA | CTD | PMID:37019170 | Gcc2 | Rat | clorgyline | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Clorgyline results in increased expression of GCC2 mRNA | CTD | PMID:19691856 | Gcc2 | Rat | clozapine | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Clozapine results in decreased expression of GCC2 protein | CTD | PMID:34122009 | Gcc2 | Rat | cobalt dichloride | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of GCC2 mRNA | CTD | PMID:19376846 | Gcc2 | Rat | copper(II) sulfate | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of GCC2 mRNA | CTD | PMID:19549813 | Gcc2 | Rat | cyclosporin A | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of GCC2 mRNA | CTD | PMID:19770486 | Gcc2 | Rat | cyclosporin A | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of GCC2 mRNA | CTD | PMID:25562108 | Gcc2 | Rat | DDT | decreases expression | EXP | | 6480464 | DDT results in decreased expression of GCC2 mRNA | CTD | PMID:30207508 | Gcc2 | Rat | diarsenic trioxide | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of GCC2 mRNA | CTD | PMID:22521957 | Gcc2 | Rat | Dibutyl phosphate | affects expression | ISO | GCC2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of GCC2 mRNA | CTD | PMID:37042841 | Gcc2 | Rat | dicrotophos | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of GCC2 mRNA | CTD | PMID:28302478 | Gcc2 | Rat | dimethylselenide | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of GCC2-AS1 more ... | CTD | PMID:33656867 | Gcc2 | Rat | dorsomorphin | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Gcc2 | Rat | ethanol | affects splicing | ISO | Gcc2 (Mus musculus) | 6480464 | Ethanol affects the splicing of GCC2 mRNA | CTD | PMID:30319688 | Gcc2 | Rat | ethyl methanesulfonate | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of GCC2 mRNA | CTD | PMID:23649840 | Gcc2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of GCC2 mRNA | CTD | PMID:24136188 | Gcc2 | Rat | folic acid | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of GCC2 mRNA | CTD | PMID:25629700 | Gcc2 | Rat | formaldehyde | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of GCC2 mRNA | CTD | PMID:23649840 | Gcc2 | Rat | FR900359 | decreases phosphorylation | ISO | GCC2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of GCC2 protein | CTD | PMID:37730182 | Gcc2 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of GCC2 mRNA | CTD | PMID:33387578 | Gcc2 | Rat | hydroxyl | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of GCC2-AS1 more ... | CTD | PMID:33656867 | Gcc2 | Rat | methyl methanesulfonate | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of GCC2 mRNA | CTD | PMID:23649840 | Gcc2 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of GCC2 mRNA | CTD | PMID:25729387 | Gcc2 | Rat | ozone | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268 | Gcc2 | Rat | paracetamol | affects expression | ISO | Gcc2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of GCC2 mRNA | CTD | PMID:17562736 | Gcc2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of GCC2 mRNA | CTD | PMID:33387578 | Gcc2 | Rat | paracetamol | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of GCC2 mRNA | CTD | PMID:21420995 | Gcc2 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of GCC2 mRNA | CTD | PMID:27153767 | Gcc2 | Rat | phenylmercury acetate | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of GCC2 mRNA | CTD | PMID:26272509 | Gcc2 | Rat | phenylmercury acetate | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Gcc2 | Rat | potassium dichromate | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of GCC2 mRNA | CTD | PMID:23608068 | Gcc2 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of GCC2 mRNA | CTD | PMID:22698814 | Gcc2 | Rat | Propiverine | affects binding | EXP | | 6480464 | propiverine binds to GCC2 protein | CTD | PMID:29273565 | Gcc2 | Rat | SB 431542 | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Gcc2 | Rat | serpentine asbestos | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Asbestos, Serpentine results in increased expression of GCC2 mRNA | CTD | PMID:21148743 | Gcc2 | Rat | silicon dioxide | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of GCC2 mRNA | CTD | PMID:25895662 | Gcc2 | Rat | sodium arsenate | decreases expression | ISO | Gcc2 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of GCC2 mRNA | CTD | PMID:39847705 | Gcc2 | Rat | sodium arsenite | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of GCC2 mRNA | CTD | PMID:28595984|PMID:34032870 | Gcc2 | Rat | sodium arsenite | multiple interactions | ISO | GCC2 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [GCC2 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | Gcc2 | Rat | sodium arsenite | increases expression | ISO | GCC2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of GCC2 mRNA | CTD | PMID:38568856 | Gcc2 | Rat | tetrachloromethane | increases expression | ISO | Gcc2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of GCC2 mRNA | CTD | PMID:31919559 | Gcc2 | Rat | tetraphene | increases expression | ISO | Gcc2 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of GCC2 mRNA | CTD | PMID:26377693 | Gcc2 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of GCC2 mRNA | CTD | PMID:34492290 | Gcc2 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of GCC2 mRNA | CTD | PMID:25729387 | Gcc2 | Rat | tributylstannane | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of GCC2 mRNA | CTD | PMID:31129395 | Gcc2 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of GCC2 mRNA | CTD | PMID:33387578 | Gcc2 | Rat | triphenyl phosphate | affects expression | ISO | GCC2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of GCC2 mRNA | CTD | PMID:37042841 | Gcc2 | Rat | triticonazole | increases expression | EXP | | 6480464 | triticonazole results in increased expression of GCC2 mRNA | CTD | PMID:36084822 | Gcc2 | Rat | valproic acid | affects expression | ISO | Gcc2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of GCC2 mRNA | CTD | PMID:17963808 | Gcc2 | Rat | valproic acid | decreases expression | ISO | GCC2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of GCC2 mRNA | CTD | PMID:23179753 | Gcc2 | Rat | valproic acid | affects expression | ISO | GCC2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GCC2 mRNA | CTD | PMID:25979313 | Gcc2 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of GCC2 mRNA | CTD | PMID:29427782 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















