Ube2e2 (ubiquitin-conjugating enzyme E2E 2) - Rat Genome Database

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Gene: Ube2e2 (ubiquitin-conjugating enzyme E2E 2) Rattus norvegicus
Analyze
Symbol: Ube2e2
Name: ubiquitin-conjugating enzyme E2E 2
RGD ID: 1305644
Description: Predicted to enable ISG15 transferase activity and ubiquitin conjugating enzyme activity. Predicted to be involved in protein modification by small protein conjugation. Predicted to act upstream of or within DNA damage response; negative regulation of gene expression; and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human UBE2E2 (ubiquitin conjugating enzyme E2 E2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361013; ubiquitin-conjugating enzyme E2 E2; ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8159,411,067 - 9,688,731 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl159,411,539 - 9,712,661 (+)EnsemblGRCr8
mRatBN7.2156,980,241 - 7,257,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl156,980,474 - 7,257,532 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx159,117,264 - 9,395,237 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01510,030,041 - 10,308,015 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0158,330,495 - 8,608,451 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0157,402,210 - 7,928,320 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl157,871,497 - 7,927,939 (+)Ensemblrn6Rnor6.0
Rnor_5.01511,469,650 - 11,995,676 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4158,554,863 - 8,828,088 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera157,042,822 - 7,313,674 (+)NCBICelera
RGSC_v3.1158,554,863 - 8,827,742 (+)NCBI
Cytogenetic Map15p16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cyclosporin A  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
fenbendazole  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
graphite  (EXP)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel sulfate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score. Eze IC, etal., Environ Int. 2016 Sep;94:263-271. doi: 10.1016/j.envint.2016.04.032. Epub 2016 Jun 6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9371400   PMID:12477932   PMID:16428300   PMID:20061386   PMID:21628527   PMID:27914986  


Genomics

Comparative Map Data
Ube2e2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8159,411,067 - 9,688,731 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl159,411,539 - 9,712,661 (+)EnsemblGRCr8
mRatBN7.2156,980,241 - 7,257,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl156,980,474 - 7,257,532 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx159,117,264 - 9,395,237 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01510,030,041 - 10,308,015 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0158,330,495 - 8,608,451 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0157,402,210 - 7,928,320 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl157,871,497 - 7,927,939 (+)Ensemblrn6Rnor6.0
Rnor_5.01511,469,650 - 11,995,676 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4158,554,863 - 8,828,088 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera157,042,822 - 7,313,674 (+)NCBICelera
RGSC_v3.1158,554,863 - 8,827,742 (+)NCBI
Cytogenetic Map15p16NCBI
UBE2E2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38323,203,098 - 23,591,925 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl323,203,020 - 23,591,794 (+)Ensemblhg38GRCh38
GRCh37323,244,589 - 23,633,416 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36323,219,812 - 23,607,074 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34323,219,811 - 23,607,074NCBI
Celera323,181,176 - 23,568,475 (+)NCBICelera
Cytogenetic Map3p24.3NCBI
HuRef323,195,983 - 23,578,212 (+)NCBIHuRef
CHM1_1323,196,572 - 23,584,124 (+)NCBICHM1_1
T2T-CHM13v2.0323,208,135 - 23,596,988 (+)NCBIT2T-CHM13v2.0
Ube2e2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39143,575,429 - 3,896,133 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl143,575,429 - 3,896,121 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381418,573,563 - 18,894,284 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1418,573,575 - 18,894,267 (-)Ensemblmm10GRCm38
MGSCv371419,406,091 - 19,726,141 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361417,366,703 - 17,686,753 (-)NCBIMGSCv36mm8
Celera1414,258,953 - 14,589,761 (-)NCBICelera
Cytogenetic Map14A1NCBI
cM Map147.08NCBI
Ube2e2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543015,122,377 - 15,441,523 (+)Ensembl
ChiLan1.0NW_00495543015,122,373 - 15,442,264 (+)NCBIChiLan1.0ChiLan1.0
UBE2E2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2223,164,902 - 23,550,662 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1323,169,694 - 23,555,428 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0323,121,699 - 23,502,329 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1323,440,772 - 23,826,027 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl323,446,158 - 23,825,277 (+)EnsemblpanPan2panpan1.1
UBE2E2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12320,110,128 - 20,593,767 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2320,130,230 - 20,486,399 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2320,126,888 - 20,601,866 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02320,441,820 - 20,915,867 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2320,442,596 - 20,811,888 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12320,250,902 - 20,782,556 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02320,360,456 - 20,837,497 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02320,469,605 - 20,997,864 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ube2e2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118181,850,218 - 182,142,077 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647314,988,802 - 15,280,650 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE2E2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl139,998,199 - 10,380,556 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1139,998,097 - 10,380,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21311,329,305 - 11,329,480 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBE2E2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11567,885,721 - 68,263,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604141,006,105 - 41,386,722 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ube2e2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11289,149,205 - 89,419,365 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ube2e2
3224 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:291
Count of miRNA genes:191
Interacting mature miRNAs:213
Transcripts:ENSRNOT00000046879
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
1300142Bp191Blood pressure QTL 1913.14arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)15115177511Rat

Markers in Region
D15Got11  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8159,612,921 - 9,613,202 (+)Marker Load Pipeline
mRatBN7.2157,182,101 - 7,182,382 (+)MAPPERmRatBN7.2
Rnor_6.0157,852,893 - 7,853,173NCBIRnor6.0
Rnor_5.01511,920,249 - 11,920,529UniSTSRnor5.0
RGSC_v3.4158,752,426 - 8,752,707RGDRGSC3.4
RGSC_v3.4158,752,427 - 8,752,707UniSTSRGSC3.4
Celera157,238,079 - 7,238,359UniSTS
RGSC_v3.1158,752,427 - 8,752,707RGD
RH 3.4 Map1595.3RGD
RH 3.4 Map1595.3UniSTS
RH 2.0 Map1550.7RGD
Cytogenetic Map15p16UniSTS
D15Mco16  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8158,687,763 - 8,687,912 (+)Marker Load Pipeline
mRatBN7.2156,256,908 - 6,257,057 (+)MAPPERmRatBN7.2
Rnor_6.0157,430,229 - 7,430,377NCBIRnor6.0
Rnor_5.01511,497,180 - 11,497,328UniSTSRnor5.0
RGSC_v3.4157,804,369 - 7,804,518RGDRGSC3.4
RGSC_v3.4157,804,370 - 7,804,518UniSTSRGSC3.4
Celera156,329,629 - 6,329,777UniSTS
RGSC_v3.1157,804,369 - 7,804,518RGD
Cytogenetic Map15p16UniSTS
D3S3993  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,257,660 - 7,257,908 (+)MAPPERmRatBN7.2
Rnor_6.0157,928,068 - 7,928,315NCBIRnor6.0
Rnor_5.01511,995,424 - 11,995,671UniSTSRnor5.0
RGSC_v3.4158,828,217 - 8,828,464UniSTSRGSC3.4
Celera157,313,803 - 7,314,050UniSTS
Cytogenetic Map15p16UniSTS
RH129032  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,493,152 - 7,493,356 (+)MAPPERmRatBN7.2
Rnor_6.0158,177,996 - 8,178,199NCBIRnor6.0
Rnor_5.01512,240,037 - 12,240,240UniSTSRnor5.0
RGSC_v3.4159,071,441 - 9,071,644UniSTSRGSC3.4
Celera157,546,445 - 7,546,648UniSTS
RH 3.4 Map1572.2UniSTS
Cytogenetic Map15p16UniSTS
D4Mit282  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01511,884,198 - 11,884,360NCBIRnor5.0
Rnor_5.01511,884,216 - 11,884,360NCBIRnor5.0
RGSC_v3.4158,716,278 - 8,716,439UniSTSRGSC3.4
RGSC_v3.4158,716,296 - 8,716,439UniSTSRGSC3.4
Celera157,202,590 - 7,202,733UniSTS
Celera157,202,572 - 7,202,733UniSTS
Cytogenetic Map15p16UniSTS
AW532084  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,132,041 - 7,132,236 (+)MAPPERmRatBN7.2
Rnor_6.0157,802,900 - 7,803,094NCBIRnor6.0
Rnor_5.01511,870,256 - 11,870,450UniSTSRnor5.0
RGSC_v3.4158,702,335 - 8,702,529UniSTSRGSC3.4
Celera157,188,629 - 7,188,823UniSTS
RH 3.4 Map1593.3UniSTS
Cytogenetic Map15p16UniSTS
BE120096  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,452,809 - 7,452,989 (+)MAPPERmRatBN7.2
Rnor_6.0158,137,940 - 8,138,119NCBIRnor6.0
Rnor_5.01512,200,843 - 12,201,022UniSTSRnor5.0
RGSC_v3.4159,029,607 - 9,029,786UniSTSRGSC3.4
Celera157,508,068 - 7,508,247UniSTS
RH 3.4 Map1573.3UniSTS
Cytogenetic Map15p16UniSTS
RH141730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,437,329 - 7,437,543 (+)MAPPERmRatBN7.2
Rnor_6.0158,122,464 - 8,122,677NCBIRnor6.0
Rnor_5.01512,185,520 - 12,185,733UniSTSRnor5.0
RGSC_v3.4159,014,055 - 9,014,268UniSTSRGSC3.4
Celera157,492,894 - 7,493,107UniSTS
RH 3.4 Map1591.7UniSTS
Cytogenetic Map15p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
20 13 71 167 91 90 59 122 59 6 428 228 14 150 113 99 31 20 20

Sequence


Ensembl Acc Id: ENSRNOT00000046879   ⟹   ENSRNOP00000049082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl159,411,628 - 9,688,731 (+)Ensembl
mRatBN7.2 Ensembl156,986,277 - 7,257,532 (+)Ensembl
Rnor_6.0 Ensembl157,871,497 - 7,927,939 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105543   ⟹   ENSRNOP00000087029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl159,411,628 - 9,688,731 (+)Ensembl
mRatBN7.2 Ensembl156,980,474 - 7,257,532 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121480   ⟹   ENSRNOP00000103882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl159,411,539 - 9,688,731 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000137756   ⟹   ENSRNOP00000102368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl159,411,539 - 9,712,661 (+)Ensembl
RefSeq Acc Id: NM_001108371   ⟹   NP_001101841
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,620 - 9,688,731 (+)NCBI
mRatBN7.2156,980,794 - 7,257,912 (+)NCBI
Rnor_6.0157,402,247 - 7,927,939 (+)NCBI
Rnor_5.01511,469,650 - 11,995,676 (+)NCBI
RGSC_v3.4158,554,863 - 8,828,088 (+)RGD
Celera157,042,822 - 7,313,674 (+)RGD
Sequence:
RefSeq Acc Id: NM_001399659   ⟹   NP_001386588
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,067 - 9,688,731 (+)NCBI
mRatBN7.2156,980,241 - 7,257,912 (+)NCBI
RefSeq Acc Id: NM_001399660   ⟹   NP_001386589
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,067 - 9,688,731 (+)NCBI
mRatBN7.2156,980,241 - 7,257,912 (+)NCBI
RefSeq Acc Id: NM_001399661   ⟹   NP_001386590
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,411,620 - 9,688,731 (+)NCBI
mRatBN7.2156,980,794 - 7,257,912 (+)NCBI
RefSeq Acc Id: NP_001101841   ⟸   NM_001108371
- Peptide Label: isoform 1
- UniProtKB: D3ZYE1 (UniProtKB/TrEMBL),   A6K030 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049082   ⟸   ENSRNOT00000046879
Ensembl Acc Id: ENSRNOP00000087029   ⟸   ENSRNOT00000105543
RefSeq Acc Id: NP_001386589   ⟸   NM_001399660
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A2G8 (UniProtKB/TrEMBL),   A6K029 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386588   ⟸   NM_001399659
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A2G8 (UniProtKB/TrEMBL),   A6K029 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386590   ⟸   NM_001399661
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A2G8 (UniProtKB/TrEMBL),   A6K029 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102368   ⟸   ENSRNOT00000137756
Ensembl Acc Id: ENSRNOP00000103882   ⟸   ENSRNOT00000121480
Protein Domains
UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZYE1-F1-model_v2 AlphaFold D3ZYE1 1-126 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305644 AgrOrtholog
BioCyc Gene G2FUF-14476 BioCyc
BioCyc Pathway PWY-7511 [protein ubiquitination] BioCyc
BioCyc Pathway Image PWY-7511 BioCyc
Ensembl Genes ENSRNOG00000032690 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046879 ENTREZGENE
  ENSRNOT00000046879.5 UniProtKB/TrEMBL
  ENSRNOT00000105543.2 UniProtKB/TrEMBL
  ENSRNOT00000121480 ENTREZGENE
  ENSRNOT00000121480.1 UniProtKB/TrEMBL
  ENSRNOT00000137756.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127579 IMAGE-MGC_LOAD
  IMAGE:7382303 IMAGE-MGC_LOAD
InterPro UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/TrEMBL
KEGG Report rno:361013 UniProtKB/TrEMBL
MGC_CLONE MGC:116336 IMAGE-MGC_LOAD
  MGC:94146 IMAGE-MGC_LOAD
NCBI Gene 361013 ENTREZGENE
PANTHER UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
Pfam UQ_con UniProtKB/TrEMBL
PhenoGen Ube2e2 PhenoGen
PROSITE UBIQUITIN_CONJUGAT_1 UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032690 RatGTEx
SMART UBCc UniProtKB/TrEMBL
Superfamily-SCOP SSF54495 UniProtKB/TrEMBL
UniProt A0A8I6A2G8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L3K5_RAT UniProtKB/TrEMBL
  A0ABK0LL26_RAT UniProtKB/TrEMBL
  A6K029 ENTREZGENE, UniProtKB/TrEMBL
  A6K030 ENTREZGENE, UniProtKB/TrEMBL
  D3ZYE1 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLJ5_RAT UniProtKB/TrEMBL
  Q6AY98_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Ube2e2  ubiquitin-conjugating enzyme E2E 2  LOC683661  similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)  Data merged from RGD:1584491 1643240 APPROVED
2011-08-01 Ube2e2  ubiquitin-conjugating enzyme E2E 2  Ube2e2  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC683661  similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Ube2e2  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)  Ube2e2_predicted  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ube2e2_predicted  ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) (predicted)      Symbol and Name status set to approved 70820 APPROVED