Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmem123 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM123 mRNA | CTD | PMID:36331819 | Tmem123 | Rat | 1,1-dichloroethene | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of TMEM123 mRNA | CTD | PMID:26682919 | Tmem123 | Rat | 1,2-dichloroethane | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TMEM123 mRNA | CTD | PMID:28960355 | Tmem123 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of TMEM123 mRNA | CTD | PMID:22206623 | Tmem123 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TMEM123 mRNA | CTD | PMID:22206623 | Tmem123 | Rat | 17beta-estradiol | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Estradiol results in increased expression of TMEM123 mRNA | CTD | PMID:39298647 | Tmem123 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM123 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:23152189|PMID:26238291 | Tmem123 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TMEM123 mRNA | CTD | PMID:33387578|PMID:34747641 | Tmem123 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TMEM123 mRNA | CTD | PMID:33956508 | Tmem123 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of TMEM123 mRNA | CTD | PMID:27914987 | Tmem123 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | bisphenol S results in increased expression of TMEM123 mRNA | CTD | PMID:39298647 | Tmem123 | Rat | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TMEM123 mRNA | CTD | PMID:30047161 | Tmem123 | Rat | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of TMEM123 mRNA | CTD | PMID:23637816 | Tmem123 | Rat | all-trans-retinoic acid | increases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TMEM123 mRNA | CTD | PMID:33167477 | Tmem123 | Rat | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of TMEM123 mRNA | CTD | PMID:30047161 | Tmem123 | Rat | antirheumatic drug | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TMEM123 mRNA | CTD | PMID:24449571 | Tmem123 | Rat | aristolochic acid A | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TMEM123 mRNA | CTD | PMID:33212167 | Tmem123 | Rat | Aroclor 1254 | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of TMEM123 mRNA | CTD | PMID:23650126 | Tmem123 | Rat | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | benzo[a]pyrene | increases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of TMEM123 mRNA | CTD | PMID:20064835 | Tmem123 | Rat | benzo[a]pyrene | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TMEM123 mRNA | CTD | PMID:19770486 | Tmem123 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TMEM123 mRNA | CTD | PMID:34319233 | Tmem123 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of TMEM123 mRNA | CTD | PMID:33754040 | Tmem123 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TMEM123 mRNA | CTD | PMID:25181051 | Tmem123 | Rat | bisphenol A | multiple interactions | ISO | TMEM123 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of TMEM123 gene | CTD | PMID:31601247 | Tmem123 | Rat | bisphenol A | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TMEM123 mRNA | CTD | PMID:33221593 | Tmem123 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TMEM123 mRNA | CTD | PMID:34947998 | Tmem123 | Rat | bisphenol A | affects expression | ISO | TMEM123 (Homo sapiens) | 6480464 | bisphenol A affects the expression of TMEM123 mRNA | CTD | PMID:30903817 | Tmem123 | Rat | bisphenol F | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | bisphenol F results in increased expression of TMEM123 mRNA | CTD | PMID:38685157 | Tmem123 | Rat | Butylbenzyl phthalate | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased expression of TMEM123 mRNA | CTD | PMID:28392331 | Tmem123 | Rat | Butylbenzyl phthalate | decreases expression | EXP | | 6480464 | butylbenzyl phthalate results in decreased expression of TMEM123 mRNA | CTD | PMID:21241498 | Tmem123 | Rat | cadmium atom | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TMEM123 more ... | CTD | PMID:28111341 | Tmem123 | Rat | cadmium dichloride | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TMEM123 mRNA | CTD | PMID:38568856 | Tmem123 | Rat | cadmium dichloride | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TMEM123 more ... | CTD | PMID:28111341 | Tmem123 | Rat | CGP 52608 | multiple interactions | ISO | TMEM123 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TMEM123 gene] | CTD | PMID:28238834 | Tmem123 | Rat | chlordecone | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of TMEM123 mRNA | CTD | PMID:33711761 | Tmem123 | Rat | chloropicrin | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of TMEM123 mRNA | CTD | PMID:26352163 | Tmem123 | Rat | chlorpyrifos | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TMEM123 mRNA | CTD | PMID:37019170 | Tmem123 | Rat | choline | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Tmem123 | Rat | cisplatin | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of TMEM123 mRNA | CTD | PMID:27392435 | Tmem123 | Rat | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | cobalt dichloride | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TMEM123 mRNA | CTD | PMID:19320972 | Tmem123 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of TMEM123 mRNA | CTD | PMID:26577399 | Tmem123 | Rat | cyclosporin A | increases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TMEM123 mRNA | CTD | PMID:20106945 | Tmem123 | Rat | D-glucose | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of TMEM123 mRNA | CTD | PMID:23637816 | Tmem123 | Rat | dibutyl phthalate | increases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of TMEM123 mRNA | CTD | PMID:21266533 | Tmem123 | Rat | dicrotophos | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of TMEM123 mRNA | CTD | PMID:28302478 | Tmem123 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of TMEM123 mRNA | CTD | PMID:23637816 | Tmem123 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TMEM123 mRNA | CTD | PMID:29391264 | Tmem123 | Rat | enzyme inhibitor | multiple interactions | ISO | TMEM123 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Tmem123 | Rat | folic acid | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TMEM123 mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Tmem123 | Rat | folic acid | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TMEM123 mRNA | CTD | PMID:25629700 | Tmem123 | Rat | fulvestrant | multiple interactions | ISO | TMEM123 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of TMEM123 gene | CTD | PMID:31601247 | Tmem123 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TMEM123 mRNA | CTD | PMID:27387713 | Tmem123 | Rat | glucose | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of TMEM123 mRNA | CTD | PMID:23637816 | Tmem123 | Rat | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of TMEM123 mRNA | CTD | PMID:24395379 | Tmem123 | Rat | GSK-J4 | increases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | GSK-J4 results in increased expression of TMEM123 mRNA | CTD | PMID:29301935 | Tmem123 | Rat | herbicide | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Herbicides results in decreased expression of TMEM123 mRNA | CTD | PMID:28711546 | Tmem123 | Rat | hydrogen peroxide | affects expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of TMEM123 mRNA | CTD | PMID:20044591 | Tmem123 | Rat | inulin | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TMEM123 mRNA | CTD | PMID:36331819 | Tmem123 | Rat | irinotecan | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Irinotecan analog results in decreased expression of TMEM123 mRNA | CTD | PMID:18927307 | Tmem123 | Rat | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | L-methionine | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Tmem123 | Rat | methamphetamine | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM123 mRNA | CTD | PMID:19564919 | Tmem123 | Rat | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of TMEM123 mRNA | CTD | PMID:19564919 | Tmem123 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of TMEM123 mRNA | CTD | PMID:30047161 | Tmem123 | Rat | methyl methanesulfonate | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of TMEM123 mRNA | CTD | PMID:23649840 | Tmem123 | Rat | nitrates | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of TMEM123 more ... | CTD | PMID:35964746 | Tmem123 | Rat | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TMEM123 mRNA | CTD | PMID:33387578 | Tmem123 | Rat | pentachlorophenol | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Pentachlorophenol results in decreased expression of TMEM123 mRNA | CTD | PMID:23892564 | Tmem123 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of TMEM123 mRNA | CTD | PMID:27153767 | Tmem123 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tmem123 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM123 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Tmem123 | Rat | phenobarbital | affects expression | ISO | Tmem123 (Mus musculus) | 6480464 | Phenobarbital affects the expression of TMEM123 mRNA | CTD | PMID:23091169 | Tmem123 | Rat | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | SCH 23390 | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM123 mRNA | CTD | PMID:19564919 | Tmem123 | Rat | silicon dioxide | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of TMEM123 mRNA | CTD | PMID:19073995 | Tmem123 | Rat | sodium arsenite | increases methylation | ISO | Tmem123 (Mus musculus) | 6480464 | sodium arsenite results in increased methylation of TMEM123 gene | CTD | PMID:32068019 | Tmem123 | Rat | sodium arsenite | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TMEM123 mRNA | CTD | PMID:38568856 | Tmem123 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of TMEM123 mRNA | CTD | PMID:30047161 | Tmem123 | Rat | sunitinib | increases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TMEM123 mRNA | CTD | PMID:31533062 | Tmem123 | Rat | T-2 toxin | decreases expression | EXP | | 6480464 | T-2 Toxin results in decreased expression of TMEM123 mRNA | CTD | PMID:26141394 | Tmem123 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TMEM123 mRNA | CTD | PMID:31150632 | Tmem123 | Rat | tetrachloromethane | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of TMEM123 mRNA | CTD | PMID:31919559 | Tmem123 | Rat | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of TMEM123 mRNA | CTD | PMID:19483382 | Tmem123 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TMEM123 mRNA | CTD | PMID:34492290 | Tmem123 | Rat | thiram | decreases expression | ISO | TMEM123 (Homo sapiens) | 6480464 | Thiram results in decreased expression of TMEM123 mRNA | CTD | PMID:38568856 | Tmem123 | Rat | titanium dioxide | increases methylation | ISO | Tmem123 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of TMEM123 promoter | CTD | PMID:35295148 | Tmem123 | Rat | triptonide | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | triptonide results in decreased expression of TMEM123 mRNA | CTD | PMID:33045310 | Tmem123 | Rat | trovafloxacin | decreases expression | ISO | Tmem123 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of TMEM123 mRNA | CTD | PMID:35537566 | Tmem123 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of TMEM123 mRNA | CTD | PMID:19015723 | | |||||||||||||||||||||||||||||||||||||||||||||||||






















