Fam241b (family with sequence similarity 241 member B) - Rat Genome Database

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Gene: Fam241b (family with sequence similarity 241 member B) Rattus norvegicus
Analyze
Symbol: Fam241b (Ensembl: Fam241b-ps1)
Name: family with sequence similarity 241 member B (Ensembl:family with sequence similarity 241 member B, pseudogene 1)
RGD ID: 1305587
Description: Predicted to be located in membrane. Orthologous to human FAM241B (family with sequence similarity 241 member B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC294499; LOC294499; RGD1305587; similar to RIKEN cDNA 2010107G23; uncharacterized protein C10orf35 homolog; uncharacterized protein LOC294499
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Fam241b-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82030,595,082 - 30,598,007 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2030,595,084 - 30,597,844 (-)EnsemblGRCr8
GRCr8 Ensembl627,935,052 - 27,935,414 (+)EnsemblGRCr8
mRatBN7.22030,052,315 - 30,055,247 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl622,183,240 - 22,183,602 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl2030,052,324 - 30,055,084 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2031,063,279 - 31,066,040 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,454,175 - 30,456,935 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,196,962 - 31,199,725 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02031,734,297 - 31,736,115 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2031,734,183 - 31,736,212 (-)Ensemblrn6Rnor6.0
Rnor_5.02033,529,900 - 33,531,718 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42029,495,045 - 29,497,738 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2031,475,962 - 31,478,723 (-)NCBICelera
RGSC_v3.12029,508,844 - 29,533,928 (-)NCBI
Cytogenetic Map20q11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Fam241b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82030,595,082 - 30,598,007 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2030,595,084 - 30,597,844 (-)EnsemblGRCr8
GRCr8 Ensembl627,935,052 - 27,935,414 (+)EnsemblGRCr8
mRatBN7.22030,052,315 - 30,055,247 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl622,183,240 - 22,183,602 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl2030,052,324 - 30,055,084 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2031,063,279 - 31,066,040 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,454,175 - 30,456,935 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,196,962 - 31,199,725 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02031,734,297 - 31,736,115 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2031,734,183 - 31,736,212 (-)Ensemblrn6Rnor6.0
Rnor_5.02033,529,900 - 33,531,718 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42029,495,045 - 29,497,738 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2031,475,962 - 31,478,723 (-)NCBICelera
RGSC_v3.12029,508,844 - 29,533,928 (-)NCBI
Cytogenetic Map20q11NCBI
FAM241B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381069,630,247 - 69,633,596 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1069,630,241 - 69,633,614 (+)Ensemblhg38GRCh38
GRCh371071,390,003 - 71,393,352 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361071,060,009 - 71,063,361 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341071,060,019 - 71,063,353NCBI
Celera1064,666,901 - 64,670,261 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1065,379,813 - 65,383,171 (+)NCBIHuRef
CHM1_11071,671,746 - 71,675,098 (+)NCBICHM1_1
T2T-CHM13v2.01070,498,296 - 70,501,645 (+)NCBIT2T-CHM13v2.0
Fam241b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391061,943,435 - 61,946,829 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1061,943,434 - 61,979,699 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381062,107,656 - 62,111,050 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1062,107,655 - 62,143,920 (-)Ensemblmm10GRCm38
MGSCv371061,570,404 - 61,573,761 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361061,503,013 - 61,506,370 (-)NCBIMGSCv36mm8
Celera1063,210,169 - 63,213,526 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.34NCBI
Fam241b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543721,526,944 - 21,578,912 (-)Ensembl
ChiLan1.0NW_00495543721,526,944 - 21,529,611 (-)NCBIChiLan1.0ChiLan1.0
FAM241B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2881,780,582 - 81,784,022 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11081,785,909 - 81,789,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01066,101,063 - 66,104,500 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11068,631,970 - 68,635,276 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1068,632,184 - 68,635,276 (+)EnsemblpanPan2panpan1.1
FAM241B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1420,695,582 - 20,698,578 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha420,825,191 - 20,828,202 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0420,967,159 - 20,970,191 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl420,967,194 - 20,970,191 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1420,866,397 - 20,869,408 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0421,070,940 - 21,073,951 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0421,414,920 - 21,417,934 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fam241b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721360,387,537 - 60,390,371 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365218,880,239 - 8,934,072 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365218,880,262 - 8,883,090 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM241B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11472,558,826 - 72,646,748 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FAM241B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1961,675,173 - 61,678,573 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl961,675,710 - 61,677,024 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604822,414,789 - 22,418,189 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam241b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247543,817,019 - 3,880,056 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247543,877,248 - 3,879,984 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fam241b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11827,930,148 - 27,933,600 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fam241b
8 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:118
Count of miRNA genes:93
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000000662
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202668936256021148Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)202074558556021148Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202668936256021148Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202679235356021148Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202668936256021148Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202668936256021148Rat

Markers in Region
RH130131  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2622,183,906 - 22,184,110 (-)MAPPERmRatBN7.2
mRatBN7.22030,052,438 - 30,052,636 (+)MAPPERmRatBN7.2
Rnor_6.02031,734,414 - 31,734,611NCBIRnor6.0
Rnor_6.0624,562,376 - 24,562,579NCBIRnor6.0
Rnor_5.02033,530,017 - 33,530,214UniSTSRnor5.0
Rnor_5.0634,412,734 - 34,412,937UniSTSRnor5.0
RGSC_v3.4622,241,870 - 22,242,073UniSTSRGSC3.4
RGSC_v3.42029,495,162 - 29,495,359UniSTSRGSC3.4
Celera2031,476,079 - 31,476,276UniSTS
Celera621,724,327 - 21,724,530UniSTS
Cytogenetic Map20q11UniSTS
BF415334  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22030,051,934 - 30,052,069 (+)MAPPERmRatBN7.2
Rnor_6.02031,733,910 - 31,734,044NCBIRnor6.0
Rnor_5.02033,529,513 - 33,529,647UniSTSRnor5.0
RGSC_v3.42029,494,658 - 29,494,792UniSTSRGSC3.4
Celera2031,475,575 - 31,475,709UniSTS
RH 3.4 Map6651.4UniSTS
Cytogenetic Map20q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000000662   ⟹   ENSRNOP00000000662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2030,595,084 - 30,597,844 (-)Ensembl
mRatBN7.2 Ensembl2030,052,324 - 30,055,084 (-)Ensembl
Rnor_6.0 Ensembl2031,734,183 - 31,736,212 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000074294   ⟹   ENSRNOP00000064505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl627,935,052 - 27,935,414 (+)Ensembl
mRatBN7.2 Ensembl622,183,240 - 22,183,602 (+)Ensembl
RefSeq Acc Id: NM_001127452   ⟹   NP_001120924
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82030,595,082 - 30,597,844 (-)NCBI
mRatBN7.22030,052,322 - 30,055,084 (-)NCBI
Rnor_6.02031,734,297 - 31,736,115 (-)NCBI
Rnor_5.02033,529,900 - 33,531,718 (-)NCBI
RGSC_v3.42029,495,045 - 29,497,738 (-)RGD
Celera2031,475,962 - 31,478,723 (-)RGD
Sequence:
RefSeq Acc Id: XM_039098607   ⟹   XP_038954535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82030,595,082 - 30,598,007 (-)NCBI
mRatBN7.22030,052,315 - 30,055,247 (-)NCBI
RefSeq Acc Id: XM_039098609   ⟹   XP_038954537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82030,595,082 - 30,597,874 (-)NCBI
mRatBN7.22030,052,315 - 30,055,090 (-)NCBI
RefSeq Acc Id: NP_001120924   ⟸   NM_001127452
- UniProtKB: B0BMZ1 (UniProtKB/TrEMBL),   A6K426 (UniProtKB/TrEMBL),   M0R549 (UniProtKB/TrEMBL),   F7EPJ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000662   ⟸   ENSRNOT00000000662
RefSeq Acc Id: XP_038954535   ⟸   XM_039098607
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038954537   ⟸   XM_039098609
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000064505   ⟸   ENSRNOT00000074294
Protein Domains
DUF4605

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BMZ1-F1-model_v2 AlphaFold B0BMZ1 1-120 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305587 AgrOrtholog
BioCyc Gene G2FUF-3703 BioCyc
Ensembl Genes ENSRNOG00000000551 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000051000 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000662 ENTREZGENE
  ENSRNOT00000000662.9 UniProtKB/TrEMBL
  ENSRNOT00000074294.4 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7389133 IMAGE-MGC_LOAD
InterPro DUF4605 UniProtKB/TrEMBL
  FAM241_domain UniProtKB/TrEMBL
KEGG Report rno:294499 UniProtKB/TrEMBL
MGC_CLONE MGC:187501 IMAGE-MGC_LOAD
NCBI Gene 294499 ENTREZGENE
PANTHER DUF4605 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEIN FAM241B UniProtKB/TrEMBL
Pfam DUF4605 UniProtKB/TrEMBL
PhenoGen Fam241b PhenoGen
RatGTEx ENSRNOG00000000551 RatGTEx
  ENSRNOG00000051000 RatGTEx
UniProt A6K426 ENTREZGENE, UniProtKB/TrEMBL
  B0BMZ1 ENTREZGENE
  F7EPJ6 ENTREZGENE, UniProtKB/TrEMBL
  M0R549 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B0BMZ1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-18 Fam241b  family with sequence similarity 241 member B  RGD1305587  similar to RIKEN cDNA 2010107G23  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 RGD1305587  similar to RIKEN cDNA 2010107G23  LOC679430  hypothetical protein LOC679430  Data merged from RGD:1588333 1643240 APPROVED
2008-04-30 RGD1305587  similar to RIKEN cDNA 2010107G23   RGD1305587_predicted  similar to RIKEN cDNA 2010107G23 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC679430  hypothetical protein LOC679430      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1305587_predicted  similar to RIKEN cDNA 2010107G23 (predicted)  LOC294499_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC294499_predicted  similar to RIKEN cDNA 2010107G23 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL