Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Arb2a | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ARB2A mRNA] | CTD | PMID:31150632 | Arb2a | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Arb2a (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of ARB2A mRNA | CTD | PMID:22206623 | Arb2a | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Arb2a (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of ARB2A mRNA | CTD | PMID:31388691 | Arb2a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Arb2a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ARB2A mRNA | CTD | PMID:31961203 | Arb2a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARB2A mRNA | CTD | PMID:32109520 | Arb2a | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Arb2a (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of ARB2A mRNA | CTD | PMID:20188158 | Arb2a | Rat | aflatoxin B1 | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ARB2A mRNA | CTD | PMID:21641981 | Arb2a | Rat | aflatoxin B1 | decreases expression | ISO | Arb2a (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of ARB2A mRNA | CTD | PMID:19770486 | Arb2a | Rat | aflatoxin B1 | decreases methylation | ISO | ARB2A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ARB2A gene | CTD | PMID:27153756 | Arb2a | Rat | aflatoxin M1 | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of ARB2A mRNA | CTD | PMID:30928695 | Arb2a | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of FAM172A mRNA | CTD | PMID:38685447 | Arb2a | Rat | antirheumatic drug | increases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ARB2A mRNA | CTD | PMID:24449571 | Arb2a | Rat | aristolochic acid A | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ARB2A mRNA | CTD | PMID:33212167 | Arb2a | Rat | atrazine | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Atrazine results in decreased expression of ARB2A mRNA | CTD | PMID:22378314 | Arb2a | Rat | benzo[a]pyrene | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ARB2A mRNA | CTD | PMID:20064835|PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291 | Arb2a | Rat | benzo[a]pyrene | decreases expression | ISO | Arb2a (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ARB2A mRNA | CTD | PMID:19770486|PMID:21715664 | Arb2a | Rat | benzo[a]pyrene | increases methylation | ISO | ARB2A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ARB2A promoter | CTD | PMID:27901495 | Arb2a | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ARB2A mRNA | CTD | PMID:26238291 | Arb2a | Rat | bis(2-chloroethyl) sulfide | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Mustard Gas results in decreased expression of ARB2A mRNA | CTD | PMID:25102026 | Arb2a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARB2A mRNA | CTD | PMID:33296240 | Arb2a | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ARB2A mRNA | CTD | PMID:30816183|PMID:32528016 | Arb2a | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ARB2A mRNA | CTD | PMID:25181051 | Arb2a | Rat | bisphenol A | decreases expression | ISO | Arb2a (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ARB2A mRNA | CTD | PMID:37894381 | Arb2a | Rat | butanal | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of ARB2A mRNA | CTD | PMID:26079696 | Arb2a | Rat | cadmium atom | multiple interactions | ISO | Arb2a (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ARB2A more ... | CTD | PMID:37236586 | Arb2a | Rat | cadmium dichloride | multiple interactions | ISO | Arb2a (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ARB2A more ... | CTD | PMID:37236586 | Arb2a | Rat | chitosan | multiple interactions | ISO | ARB2A (Homo sapiens) | 6480464 | ARB2A protein affects the reaction [Chitosan results in decreased expression of CPE protein]; ARB2A protein more ... | CTD | PMID:36706893 | Arb2a | Rat | chitosan | increases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Chitosan results in increased expression of ARB2A mRNA | CTD | PMID:36706893 | Arb2a | Rat | copper(II) sulfate | increases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ARB2A mRNA | CTD | PMID:19549813 | Arb2a | Rat | cyclosporin A | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ARB2A mRNA | CTD | PMID:25562108 | Arb2a | Rat | dorsomorphin | multiple interactions | ISO | ARB2A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Arb2a | Rat | doxorubicin | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ARB2A mRNA | CTD | PMID:29803840 | Arb2a | Rat | formaldehyde | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ARB2A mRNA | CTD | PMID:23649840 | Arb2a | Rat | FR900359 | increases phosphorylation | ISO | ARB2A (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of ARB2A protein | CTD | PMID:37730182 | Arb2a | Rat | geldanamycin | increases expression | ISO | ARB2A (Homo sapiens) | 6480464 | geldanamycin results in increased expression of ARB2A mRNA | CTD | PMID:26705709 | Arb2a | Rat | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of ARB2A gene | CTD | PMID:35440735 | Arb2a | Rat | mercury dichloride | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of ARB2A mRNA | CTD | PMID:27188386 | Arb2a | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ARB2A gene | CTD | PMID:35440735 | Arb2a | Rat | O-methyleugenol | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of ARB2A mRNA | CTD | PMID:32234424 | Arb2a | Rat | okadaic acid | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of ARB2A mRNA | CTD | PMID:38832940 | Arb2a | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [Oxaliplatin co-treated with Topotecan] results in decreased expression of ARB2A mRNA | CTD | PMID:25729387 | Arb2a | Rat | paracetamol | increases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ARB2A mRNA | CTD | PMID:26690555 | Arb2a | Rat | pirinixic acid | multiple interactions | ISO | Arb2a (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Arb2a | Rat | potassium chromate | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of ARB2A mRNA | CTD | PMID:22714537 | Arb2a | Rat | rotenone | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Rotenone results in decreased expression of FAM172A protein | CTD | PMID:39603559 | Arb2a | Rat | SB 431542 | multiple interactions | ISO | ARB2A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Arb2a | Rat | silicon dioxide | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ARB2A mRNA | CTD | PMID:25895662 | Arb2a | Rat | sodium arsenite | decreases methylation | ISO | Arb2a (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of ARB2A gene | CTD | PMID:32068019 | Arb2a | Rat | temozolomide | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of ARB2A mRNA | CTD | PMID:31758290 | Arb2a | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ARB2A mRNA | CTD | PMID:31150632 | Arb2a | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ARB2A mRNA] | CTD | PMID:31150632 | Arb2a | Rat | thimerosal | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of ARB2A mRNA | CTD | PMID:27188386 | Arb2a | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ARB2A mRNA | CTD | PMID:34492290 | Arb2a | Rat | titanium dioxide | decreases methylation | ISO | Arb2a (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of FAM172A gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Arb2a | Rat | topotecan | multiple interactions | EXP | | 6480464 | [Oxaliplatin co-treated with Topotecan] results in decreased expression of ARB2A mRNA | CTD | PMID:25729387 | Arb2a | Rat | trichostatin A | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ARB2A mRNA | CTD | PMID:26272509 | Arb2a | Rat | trichostatin A | multiple interactions | ISO | ARB2A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Arb2a | Rat | triphenyl phosphate | affects expression | ISO | ARB2A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FAM172A mRNA | CTD | PMID:37042841 | Arb2a | Rat | triptonide | decreases expression | ISO | Arb2a (Mus musculus) | 6480464 | triptonide results in decreased expression of ARB2A mRNA | CTD | PMID:33045310 | Arb2a | Rat | urethane | increases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Urethane results in increased expression of ARB2A mRNA | CTD | PMID:28818685 | Arb2a | Rat | valproic acid | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ARB2A mRNA | CTD | PMID:23179753|PMID:24935251 | Arb2a | Rat | valproic acid | affects expression | ISO | ARB2A (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ARB2A mRNA | CTD | PMID:25979313 | Arb2a | Rat | vorinostat | decreases expression | ISO | ARB2A (Homo sapiens) | 6480464 | Vorinostat results in decreased expression of ARB2A mRNA | CTD | PMID:27188386 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















