Cables1 (Cdk5 and Abl enzyme substrate 1) - Rat Genome Database

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Gene: Cables1 (Cdk5 and Abl enzyme substrate 1) Rattus norvegicus
Analyze
Symbol: Cables1
Name: Cdk5 and Abl enzyme substrate 1
RGD ID: 1305516
Description: Predicted to be involved in nervous system development. Predicted to be active in cytosol. Orthologous to human CABLES1 (Cdk5 and Abl enzyme substrate 1); INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CDK5 and ABL1 enzyme substrate 1; LOC307585
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8183,349,681 - 3,455,956 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl183,351,652 - 3,455,956 (+)EnsemblGRCr8
mRatBN7.2183,076,556 - 3,181,181 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,075,524 - 3,181,181 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx183,316,122 - 3,419,293 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0184,103,815 - 4,206,986 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,336,580 - 3,440,755 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0183,317,724 - 3,421,721 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl183,317,724 - 3,421,721 (+)Ensemblrn6Rnor6.0
Rnor_5.0183,328,555 - 3,432,388 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4183,425,890 - 3,529,998 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera182,944,083 - 3,047,971 (+)NCBICelera
RGSC_v3.1183,425,895 - 3,528,968 (+)NCBI
Cytogenetic Map18p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-benzylpiperazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dieldrin  (EXP)
diethylstilbestrol  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
manganese(II) chloride  (EXP)
melphalan  (ISO)
menadione  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10896159   PMID:17101133   PMID:25931508  


Genomics

Comparative Map Data
Cables1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8183,349,681 - 3,455,956 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl183,351,652 - 3,455,956 (+)EnsemblGRCr8
mRatBN7.2183,076,556 - 3,181,181 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,075,524 - 3,181,181 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx183,316,122 - 3,419,293 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0184,103,815 - 4,206,986 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,336,580 - 3,440,755 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0183,317,724 - 3,421,721 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl183,317,724 - 3,421,721 (+)Ensemblrn6Rnor6.0
Rnor_5.0183,328,555 - 3,432,388 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4183,425,890 - 3,529,998 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera182,944,083 - 3,047,971 (+)NCBICelera
RGSC_v3.1183,425,895 - 3,528,968 (+)NCBI
Cytogenetic Map18p13NCBI
CABLES1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381823,134,564 - 23,260,470 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1823,134,564 - 23,260,470 (+)Ensemblhg38GRCh38
GRCh371820,714,528 - 20,840,434 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361818,969,725 - 19,092,615 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341818,989,786 - 19,092,614NCBI
Celera1817,551,596 - 17,656,291 (+)NCBICelera
Cytogenetic Map18q11.2NCBI
HuRef1817,569,503 - 17,695,108 (+)NCBIHuRef
CHM1_11820,641,871 - 20,767,758 (+)NCBICHM1_1
T2T-CHM13v2.01823,327,896 - 23,454,570 (+)NCBIT2T-CHM13v2.0
Cables1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391811,972,600 - 12,078,681 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1811,972,277 - 12,078,687 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381811,839,274 - 11,945,627 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1811,839,220 - 11,945,630 (+)Ensemblmm10GRCm38
MGSCv371811,997,783 - 12,104,136 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361811,982,810 - 12,089,100 (+)NCBIMGSCv36mm8
MGSCv361811,851,108 - 11,958,075 (+)NCBIMGSCv36mm8
Celera1812,078,718 - 12,185,440 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map185.88NCBI
Cables1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540211,414,271 - 11,513,030 (+)Ensembl
ChiLan1.0NW_00495540211,415,913 - 11,514,132 (+)NCBIChiLan1.0ChiLan1.0
CABLES1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21740,563,858 - 40,688,310 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11826,256,172 - 26,380,903 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01816,384,305 - 16,508,915 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11820,013,292 - 20,137,092 (+)NCBIPanPan1.1PanPan1.1panPan2
CABLES1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1765,006,301 - 65,124,440 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl765,008,804 - 65,124,563 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha764,460,648 - 64,526,224 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0765,071,395 - 65,136,731 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl765,072,698 - 65,188,006 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1764,739,109 - 64,804,359 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0764,761,016 - 64,826,517 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0765,059,557 - 65,125,060 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cables1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494461,057,544 - 61,166,019 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365502,653,321 - 2,756,805 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365502,650,061 - 2,759,557 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CABLES1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6108,116,444 - 108,227,744 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16108,116,344 - 108,228,832 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26100,634,496 - 100,727,232 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CABLES1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11857,253,843 - 57,378,969 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1857,257,081 - 57,378,855 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605032,005,982 - 32,131,029 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cables1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247708,837,220 - 8,935,886 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247708,837,425 - 8,937,106 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cables1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11531,665,477 - 31,767,807 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cables1
1276 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:620
Count of miRNA genes:271
Interacting mature miRNAs:349
Transcripts:ENSRNOT00000017187
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331781Scl28Serum cholesterol level QTL 283.995blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)18125071266Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18115642423Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134566578Rat
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18126032889Rat
9590248Scort10Serum corticosterone level QTL 1019.710.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)18126032889Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18144930869Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
1641910Colcr3Colorectal carcinoma resistance QTL 35.020.000007intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)18125022372Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134566578Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 83 59 6 347 183 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017187   ⟹   ENSRNOP00000017187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl183,351,652 - 3,455,956 (+)Ensembl
mRatBN7.2 Ensembl183,075,524 - 3,181,181 (+)Ensembl
Rnor_6.0 Ensembl183,317,724 - 3,421,721 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104819   ⟹   ENSRNOP00000094903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl183,351,652 - 3,455,956 (+)Ensembl
mRatBN7.2 Ensembl183,075,524 - 3,181,181 (+)Ensembl
RefSeq Acc Id: NM_001107404   ⟹   NP_001100874
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8183,351,652 - 3,455,956 (+)NCBI
mRatBN7.2183,076,865 - 3,181,181 (+)NCBI
Rnor_6.0183,317,724 - 3,421,721 (+)NCBI
Rnor_5.0183,328,555 - 3,432,388 (+)NCBI
RGSC_v3.4183,425,890 - 3,529,998 (+)RGD
Celera182,944,083 - 3,047,971 (+)RGD
Sequence:
RefSeq Acc Id: NM_001415691   ⟹   NP_001402620
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8183,351,652 - 3,455,956 (+)NCBI
mRatBN7.2183,076,865 - 3,181,181 (+)NCBI
RefSeq Acc Id: XM_039096929   ⟹   XP_038952857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8183,349,681 - 3,429,758 (+)NCBI
mRatBN7.2183,076,556 - 3,151,884 (+)NCBI
RefSeq Acc Id: XM_039096930   ⟹   XP_038952858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8183,349,681 - 3,429,758 (+)NCBI
mRatBN7.2183,076,556 - 3,151,884 (+)NCBI
RefSeq Acc Id: XM_063277454   ⟹   XP_063133524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8183,416,631 - 3,455,956 (+)NCBI
RefSeq Acc Id: NP_001100874   ⟸   NM_001107404
- Peptide Label: isoform 1
- UniProtKB: F1LUR9 (UniProtKB/TrEMBL),   A6KNG0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017187   ⟸   ENSRNOT00000017187
RefSeq Acc Id: XP_038952857   ⟸   XM_039096929
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038952858   ⟸   XM_039096930
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000094903   ⟸   ENSRNOT00000104819
RefSeq Acc Id: NP_001402620   ⟸   NM_001415691
- Peptide Label: isoform 2
- UniProtKB: A0A8I6AIM6 (UniProtKB/TrEMBL),   A6KNG0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133524   ⟸   XM_063277454
- Peptide Label: isoform X2
Protein Domains
Cyclin N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LUR9-F1-model_v2 AlphaFold F1LUR9 1-517 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305516 AgrOrtholog
BioCyc Gene G2FUF-8378 BioCyc
Ensembl Genes ENSRNOG00000012795 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017187 ENTREZGENE
  ENSRNOT00000017187.8 UniProtKB/TrEMBL
  ENSRNOT00000104819 ENTREZGENE
  ENSRNOT00000104819.2 UniProtKB/TrEMBL
Gene3D-CATH Cyclin-like UniProtKB/TrEMBL
InterPro Cdk5/c-Abl_linker_Cables UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/TrEMBL
  Cyclin_N UniProtKB/TrEMBL
KEGG Report rno:307585 UniProtKB/TrEMBL
NCBI Gene 307585 ENTREZGENE
PANTHER CDK5 AND ABL1 ENZYME SUBSTRATE 1 UniProtKB/TrEMBL
  PTHR22896 UniProtKB/TrEMBL
Pfam Cyclin_N UniProtKB/TrEMBL
PhenoGen Cables1 PhenoGen
PIRSF Cables UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012795 RatGTEx
Superfamily-SCOP Cyclin_like UniProtKB/TrEMBL
UniProt A0A8I6AIM6 ENTREZGENE, UniProtKB/TrEMBL
  A6KNG0 ENTREZGENE, UniProtKB/TrEMBL
  F1LUR9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Cables1  Cdk5 and Abl enzyme substrate 1   Cables1_predicted  Cdk5 and Abl enzyme substrate 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cables1_predicted  Cdk5 and Abl enzyme substrate 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED