Ube2c (ubiquitin-conjugating enzyme E2C) - Rat Genome Database

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Gene: Ube2c (ubiquitin-conjugating enzyme E2C) Rattus norvegicus
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Symbol: Ube2c
Name: ubiquitin-conjugating enzyme E2C
RGD ID: 1305382
Description: Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin-like protein ligase binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; protein polyubiquitination; and regulation of mitotic cell cycle phase transition. Predicted to act upstream of or within SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and positive regulation of mitotic metaphase/anaphase transition. Predicted to be part of anaphase-promoting complex. Predicted to be active in nucleus. Orthologous to human UBE2C (ubiquitin conjugating enzyme E2 C); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC296368; ubiquitin-conjugating enzyme E2 C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,925,975 - 173,928,375 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3173,925,934 - 173,932,678 (+)EnsemblGRCr8
mRatBN7.23153,506,636 - 153,509,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,506,636 - 153,513,339 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3157,315,317 - 157,317,718 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,814,287 - 165,816,688 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,558,064 - 163,560,465 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,236,971 - 161,239,371 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,236,898 - 161,241,159 (+)Ensemblrn6Rnor6.0
Rnor_5.03167,422,569 - 167,424,969 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43155,800,357 - 155,802,757 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3152,114,392 - 152,116,792 (+)NCBICelera
RGSC_v3.13155,706,427 - 155,708,790 (+)NCBI
Cytogenetic Map3q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amsacrine  (ISO)
antimony(0)  (ISO)
antimycin A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chloroprene  (ISO)
choline  (ISO)
chromium atom  (ISO)
chromium(6+)  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
corticosterone  (EXP)
Cuprizon  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucitol  (ISO)
D-glucose  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (EXP)
diisononyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
enzalutamide  (ISO)
etoposide  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
fructose  (ISO)
furan  (EXP)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glucose  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
hydroxyurea  (ISO)
indole-3-methanol  (EXP)
irinotecan  (EXP,ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (EXP,ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methimazole  (EXP)
methotrexate  (EXP,ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propanal  (ISO)
propiconazole  (ISO)
pyrimidifen  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trans-caffeic acid  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
tubocurarine  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
vincristine  (ISO)
zaragozic acid A  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9122200   PMID:12629039   PMID:15749827   PMID:17167411   PMID:18485873   PMID:19820702   PMID:19822757   PMID:20061386   PMID:21448667  


Genomics

Comparative Map Data
Ube2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,925,975 - 173,928,375 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3173,925,934 - 173,932,678 (+)EnsemblGRCr8
mRatBN7.23153,506,636 - 153,509,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,506,636 - 153,513,339 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3157,315,317 - 157,317,718 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,814,287 - 165,816,688 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,558,064 - 163,560,465 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,236,971 - 161,239,371 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,236,898 - 161,241,159 (+)Ensemblrn6Rnor6.0
Rnor_5.03167,422,569 - 167,424,969 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43155,800,357 - 155,802,757 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3152,114,392 - 152,116,792 (+)NCBICelera
RGSC_v3.13155,706,427 - 155,708,790 (+)NCBI
Cytogenetic Map3q42NCBI
UBE2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,812,644 - 45,816,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2045,812,576 - 45,816,957 (+)Ensemblhg38GRCh38
GRCh372044,441,283 - 44,445,591 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,874,662 - 43,879,003 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342043,874,661 - 43,879,001NCBI
Celera2041,151,754 - 41,156,092 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,183,027 - 41,187,357 (+)NCBIHuRef
CHM1_12044,344,397 - 44,348,735 (+)NCBICHM1_1
T2T-CHM13v2.02047,549,141 - 47,553,438 (+)NCBIT2T-CHM13v2.0
Ube2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,611,849 - 164,614,822 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,611,818 - 164,620,742 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382164,769,929 - 164,772,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,769,898 - 164,778,822 (+)Ensemblmm10GRCm38
MGSCv372164,595,429 - 164,598,402 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362164,461,134 - 164,464,107 (+)NCBIMGSCv36mm8
Celera2170,707,443 - 170,710,416 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
Ube2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,469,063 - 11,478,759 (-)Ensembl
ChiLan1.0NW_00495544511,474,826 - 11,479,479 (-)NCBIChiLan1.0ChiLan1.0
UBE2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,553,849 - 51,558,792 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,547,853 - 51,551,892 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,152,219 - 42,156,246 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,239,382 - 43,243,464 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,239,382 - 43,243,464 (+)EnsemblpanPan2panpan1.1
UBE2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,128,300 - 33,133,637 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,128,335 - 33,132,023 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2432,655,563 - 32,659,463 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02433,838,609 - 33,842,717 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,838,625 - 33,842,523 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,097,372 - 33,101,272 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,212,448 - 33,216,354 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,751,584 - 33,755,488 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ube2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,750,684 - 191,753,998 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,199,539 - 7,207,655 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,204,332 - 7,208,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,018,400 - 48,021,534 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11748,018,403 - 48,021,542 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,664,459 - 53,667,609 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBE2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,069,525 - 18,073,597 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605066,709,872 - 66,713,957 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ube2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,751,662 - 8,760,057 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247908,756,758 - 8,760,078 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ube2c
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15153,185,658 - 153,188,481 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:27
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000020323
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3166376089177728348Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat

Markers in Region
RH141512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23153,505,203 - 153,505,353 (+)MAPPERmRatBN7.2
Rnor_6.03161,235,539 - 161,235,688NCBIRnor6.0
Rnor_5.03167,421,137 - 167,421,286UniSTSRnor5.0
RGSC_v3.43155,798,925 - 155,799,074UniSTSRGSC3.4
Celera3152,112,960 - 152,113,109UniSTS
RH 3.4 Map31422.8UniSTS
Cytogenetic Map3q42UniSTS
RH128158  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map31426.8UniSTS
Cytogenetic Map3q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020323   ⟹   ENSRNOP00000020323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3173,925,934 - 173,928,368 (+)Ensembl
mRatBN7.2 Ensembl3153,506,636 - 153,509,036 (+)Ensembl
Rnor_6.0 Ensembl3161,236,971 - 161,239,371 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082303   ⟹   ENSRNOP00000074117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3161,236,898 - 161,241,159 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104083   ⟹   ENSRNOP00000081343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,506,897 - 153,509,036 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118238   ⟹   ENSRNOP00000088133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3173,925,934 - 173,932,678 (+)Ensembl
mRatBN7.2 Ensembl3153,506,636 - 153,513,339 (+)Ensembl
RefSeq Acc Id: NM_001106542   ⟹   NP_001100012
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,925,975 - 173,928,375 (+)NCBI
mRatBN7.23153,506,636 - 153,509,036 (+)NCBI
Rnor_6.03161,236,971 - 161,239,371 (+)NCBI
Rnor_5.03167,422,569 - 167,424,969 (+)NCBI
RGSC_v3.43155,800,357 - 155,802,757 (+)RGD
Celera3152,114,392 - 152,116,792 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100012 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96497 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020323
  ENSRNOP00000020323.2
  ENSRNOP00000088133.1
RefSeq Acc Id: NP_001100012   ⟸   NM_001106542
- UniProtKB: D3ZUW6 (UniProtKB/TrEMBL),   A6JXB2 (UniProtKB/TrEMBL),   A0A8I6A5K3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074117   ⟸   ENSRNOT00000082303
Ensembl Acc Id: ENSRNOP00000020323   ⟸   ENSRNOT00000020323
Ensembl Acc Id: ENSRNOP00000088133   ⟸   ENSRNOT00000118238
Ensembl Acc Id: ENSRNOP00000081343   ⟸   ENSRNOT00000104083
Protein Domains
UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUW6-F1-model_v2 AlphaFold D3ZUW6 1-179 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692664
Promoter ID:EPDNEW_R3188
Type:initiation region
Name:Ube2c_1
Description:ubiquitin-conjugating enzyme E2C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03161,236,975 - 161,237,035EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305382 AgrOrtholog
BioCyc Gene G2FUF-46830 BioCyc
BioCyc Pathway PWY-7511 [protein ubiquitination] BioCyc
BioCyc Pathway Image PWY-7511 BioCyc
Ensembl Genes ENSRNOG00000015131 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020323 ENTREZGENE
  ENSRNOT00000020323.5 UniProtKB/TrEMBL
  ENSRNOT00000118238.2 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
InterPro Ub_conjugating_enzyme UniProtKB/TrEMBL
  UBQ-conjugat/RWD-like UniProtKB/TrEMBL
  UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
KEGG Report rno:296368 UniProtKB/TrEMBL
NCBI Gene 296368 ENTREZGENE
PANTHER UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
Pfam UQ_con UniProtKB/TrEMBL
PhenoGen Ube2c PhenoGen
PROSITE UBIQUITIN_CONJUGAT_1 UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015131 RatGTEx
SMART UBCc UniProtKB/TrEMBL
Superfamily-SCOP UBQ-conjugat/RWD-like UniProtKB/TrEMBL
UniProt A0A8I6A5K3 ENTREZGENE, UniProtKB/TrEMBL
  A6JXB2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUW6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ube2c  ubiquitin-conjugating enzyme E2C   Ube2c_predicted  ubiquitin-conjugating enzyme E2C (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ube2c_predicted  ubiquitin-conjugating enzyme E2C (predicted)      Symbol and Name status set to approved 70820 APPROVED