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Gene: Srek1ip1 (SREK1-interacting protein 1) Rattus norvegicus

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Symbol:

Srek1ip1

Name:

SREK1-interacting protein 1

RGD ID:

1305356

Description:

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in RNA splicing and mRNA processing. Orthologous to human SREK1IP1 (SREK1 interacting protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cyclophosphamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC361888; MGC105985; p18SRP; RGD1305356; SFRS12-interacting protein 1; Sfrs12ip1; similar to RIKEN cDNA 3110031B13; splicing regulatory glutamine/lysine-rich protein 1 interacting protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SREK1IP1 (SREK1 interacting protein 1)	RGD	RGD
Mus musculus (house mouse):	Srek1ip1 (splicing regulatory glutamine/lysine-rich protein 1interacting protein 1)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Srek1ip1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SREK1IP1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SREK1IP1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Srek1ip1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SREK1IP1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SREK1IP1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Srek1ip1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Srek1ip1 (SREK1 interacting protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ADSL (adenylosuccinate lyase)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Srek1ip1 (splicing regulatory glutamine/lysine-rich protein 1interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Srek1ip1 (splicing regulatory glutamine/lysine-rich protein 1interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SREK1IP1 (SREK1 interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SREK1IP1 (SREK1 interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	srek1ip1 (SREK1-interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	srek1ip1 (SREK1-interacting protein 1)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C13F10.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C13F10.7	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3918	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG3918	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	srek1ip1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	srek1ip1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Related Pseudogenes:

Srek1ip1-ps1

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	37,709,712 - 37,733,391 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	37,709,768 - 37,733,383 (+)	Ensembl				GRCr8
GRCr8 Ensembl	7	114,362,342 - 114,366,194 (+)	Ensembl				GRCr8
mRatBN7.2	2	35,975,978 - 35,999,636 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	112,482,229 - 112,484,632 (+)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	2	35,975,989 - 35,999,636 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	43,086,558 - 43,108,925 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	41,145,240 - 41,167,601 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	35,999,196 - 36,022,694 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	34,923,187 - 34,940,410 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	2	54,048,975 - 54,066,198 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	35,825,856 - 35,849,470 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	31,932,199 - 31,955,703 (+)	NCBI		Celera
RGSC_v3.1	2	35,746,224 - 35,769,837 (+)	NCBI
Cytogenetic Map	2	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

caffeine (ISO)

calcitriol (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclophosphamide (EXP)

cyclosporin A (ISO)

dicrotophos (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

glutathione (EXP)

gold atom (ISO)

gold(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (EXP)

methyl methanesulfonate (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mRNA processing (IEA)

RNA splicing (IEA)

Molecular Function

metal ion binding (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15456940

Genomics

Comparative Map Data

Srek1ip1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	37,709,712 - 37,733,391 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	37,709,768 - 37,733,383 (+)	Ensembl				GRCr8
GRCr8 Ensembl	7	114,362,342 - 114,366,194 (+)	Ensembl				GRCr8
mRatBN7.2	2	35,975,978 - 35,999,636 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	112,482,229 - 112,484,632 (+)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	2	35,975,989 - 35,999,636 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	43,086,558 - 43,108,925 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	41,145,240 - 41,167,601 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	35,999,196 - 36,022,694 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	34,923,187 - 34,940,410 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	2	54,048,975 - 54,066,198 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	35,825,856 - 35,849,470 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	31,932,199 - 31,955,703 (+)	NCBI		Celera
RGSC_v3.1	2	35,746,224 - 35,769,837 (+)	NCBI
Cytogenetic Map	2	q13	NCBI

SREK1IP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	64,718,148 - 64,768,691 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	64,718,148 - 64,768,692 (-)	Ensembl			hg38	GRCh38
GRCh37	5	64,013,975 - 64,064,518 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	64,049,731 - 64,100,252 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	5	61,010,895 - 61,061,416 (-)	NCBI		Celera
Cytogenetic Map	5	q12.3	NCBI
HuRef	5	60,968,550 - 61,019,073 (-)	NCBI		HuRef
CHM1_1	5	64,013,868 - 64,064,388 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	65,538,272 - 65,588,810 (-)	NCBI		T2T-CHM13v2.0

Srek1ip1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	104,953,696 - 104,975,805 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	104,928,992 - 104,975,782 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	104,817,170 - 104,838,676 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	104,792,484 - 104,839,274 (+)	Ensembl			mm10	GRCm38
MGSCv37	13	105,607,319 - 105,628,739 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	105,937,622 - 105,959,041 (+)	NCBI		MGSCv36	mm8
Celera	13	109,211,029 - 109,232,453 (+)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI
cM Map	13	56.84	NCBI

Srek1ip1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	4,230,720 - 4,262,904 (+)	Ensembl
ChiLan1.0	NW_004955446	4,230,559 - 4,267,331 (+)	NCBI	ChiLan1.0	ChiLan1.0

SREK1IP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	49,150,856 - 49,197,975 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	47,304,487 - 47,351,606 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	49,235,538 - 49,282,707 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	50,885,711 - 50,936,168 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	50,885,902 - 50,929,930 (+)	Ensembl			panPan2	panpan1.1

SREK1IP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	50,608,356 - 50,655,163 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	50,612,272 - 50,654,746 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	47,563,355 - 47,611,859 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	51,090,668 - 51,139,537 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	51,092,381 - 51,139,006 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	48,151,279 - 48,200,084 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	48,947,176 - 48,996,015 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	49,834,660 - 49,883,418 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Srek1ip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	195,369,384 - 195,398,710 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	4,306,026 - 4,337,290 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	4,305,868 - 4,335,178 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SREK1IP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	43,297,007 - 43,346,228 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	43,113,866 - 43,346,252 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	46,527,760 - 46,572,330 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SREK1IP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	60,901,480 - 60,953,377 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	60,907,724 - 60,953,296 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666049	9,535,956 - 9,587,808 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Srek1ip1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624815	5,082,551 - 5,123,265 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Srek1ip1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	192,516,385 - 192,540,206 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Srek1ip1
201 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	160
Count of miRNA genes:	132
Interacting mature miRNAs:	144
Transcripts:	ENSRNOT00000074499
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	13325041	58325041	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	24117813	69117813	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	36750344	81750344	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	42977529	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
9590080	Insglur4	Insulin/glucose ratio QTL 4	28.7	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	2	6152767	51152767	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	35614083	53462005	Rat
1579916	Bp270	Blood pressure QTL 270		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	16051883	61051883	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	22038044	67038044	Rat
731166	Mamtr2	Mammary tumor resistance QTL 2		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	54623581	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	28889991	73889991	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	14368707	59368707	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	44538110	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	83465677	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	5736325	50736325	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	18227137	63227137	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	36868643	81868643	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1582246	Cm60	Cardiac mass QTL 60	5.8		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	33269996	78269996	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	73652666	Rat

Markers in Region

RH130035

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	35,999,363 - 35,999,551 (+)	MAPPER	mRatBN7.2
mRatBN7.2	7	112,484,367 - 112,484,555 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	122,164,300 - 122,164,487	NCBI	Rnor6.0
Rnor_5.0	7	122,156,108 - 122,156,295	UniSTS	Rnor5.0
RGSC_v3.4	7	119,228,689 - 119,228,876	UniSTS	RGSC3.4
RGSC_v3.4	2	35,849,204 - 35,849,391	UniSTS	RGSC3.4
Celera	7	108,807,930 - 108,808,117	UniSTS
Celera	2	31,955,437 - 31,955,624	UniSTS
RH 3.4 Map	7	874.7	UniSTS
Cytogenetic Map	2	q13	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH138029

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	35,978,263 - 35,978,383 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	34,925,404 - 34,925,523	NCBI	Rnor6.0
Rnor_5.0	2	54,051,192 - 54,051,311	UniSTS	Rnor5.0
RGSC_v3.4	2	35,828,073 - 35,828,192	UniSTS	RGSC3.4
Celera	2	31,934,416 - 31,934,535	UniSTS
RH 3.4 Map	2	147.4	UniSTS
Cytogenetic Map	2	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
7	1	18	52	66	137	94	11	51	36	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001008373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY236996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000074499 ⟹ ENSRNOP00000064069

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	37,714,918 - 37,733,383 (+)	Ensembl
mRatBN7.2 Ensembl	2	35,983,339 - 35,999,636 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095129 ⟹ ENSRNOP00000095882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	37,709,768 - 37,733,383 (+)	Ensembl
mRatBN7.2 Ensembl	2	35,975,989 - 35,999,636 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103086 ⟹ ENSRNOP00000090851

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	114,362,342 - 114,364,813 (+)	Ensembl
mRatBN7.2 Ensembl	7	112,482,229 - 112,484,632 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104826 ⟹ ENSRNOP00000091172

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	35,991,358 - 35,999,636 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115651 ⟹ ENSRNOP00000081440

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	35,985,430 - 35,999,636 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000144480 ⟹ ENSRNOP00000102058

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	114,362,395 - 114,363,600 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000165204 ⟹ ENSRNOP00000106751

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	114,362,389 - 114,366,194 (+)	Ensembl

RefSeq Acc Id:

NM_001008373 ⟹ NP_001008374

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	37,709,737 - 37,733,391 (+)	NCBI
mRatBN7.2	2	35,975,978 - 35,999,636 (+)	NCBI
Rnor_6.0	2	34,923,187 - 34,940,410 (+)	NCBI
Rnor_5.0	2	54,048,975 - 54,066,198 (+)	NCBI
RGSC_v3.4	2	35,825,856 - 35,849,470 (+)	RGD
Celera	2	31,932,199 - 31,955,703 (+)	RGD

Sequence:

show sequence

GGGAGAGATCCCTCTGCTAGTGCGTTGTCCTCGCTAAGGACCTGAACGAAACGCGATCTCGAAA
GCTCAGGACTCCGGTGACCCCACTCACCTGCATTATGGCAGTCCCAGGTTGCAACAAGGACAAT
GTCCGAGCAGGCTGCAGAAAATGTGGCTACCCTGGTCATCTGACTTTTGAGTGCCGCAATTTTC
TTCGGGTAGACCCCAAAAGGGACATTGTGTTGGACGTCAGCAGCACAAGCAGTGAGGACAGTGA
CGAAGAAAGCGAGGAGCTGAACAAGCTTCAGGCTCTGCAGGAGAAAAGAATAAATGAAGAAGAA
GAGAAGAAAAAGGAAAAAAGCAGGGAGAAAATTAAATTGAAAAAAAAGAGGAAAAGGTCTAACT
CCAGCACCACTGAAGAGGACTCTTCAAAACAAAAGAAACAGAAGTATCAGAAAAAAGAAAAGAA
AAAGGAAAAAAAGAACAAATCCAAAAAAGGAAAACATCACAAAAAGGAAAAAAAGAAGAGAAAA
AAGGAAAAGCGTTCTTCCCCTAACCGTTCTGAAGTCACCAAAAAGTAACAGAGTCTTGGGCCTA
ACTCAGGAAATTGAAGAATTCAGTTTTTTTAAGTATTGAACCTTCCTTGGAATTGCTATATAAT
TACGCTTTGCAGAAAAATCCCAGCCTCTTCCATAAAGACGTTTTTCACCTCCTGGGGCCCTTCC
CTCCCTGCCCGTCTGTATTAAACCCATCTCCTTACTTGACAGCTTGTCCCAAGTCTAGATGTGT
GCACTCACAGCACATCACTTTGGCTGTTTGTGTCTCGGTGTCTAGCTGTCTCGGTAAGTTAATT
AGCACGAGGCTTTCCTGCGATCAAAGGAGTAATCTACATGGCAGCTCCTGAGTCTTGTCTGCCT
TCCAGTGGTAAAGCTGCCTCGGCGGTAGTGATTCGCTCTTGATACTGAATAGCTTTATGTACTC
TGTAATGTATGGAATAGTGAAGCTCTTCACTATTGTTTTAAACCTCTAGACTTTTTAAATAACA
TCACTGAGGATAAAACCACTTTACTGATCTTAAATAGTAAGTTTTTAAATGAGTGGGATCTACA
GAAGATAATAATGAAAGTATTTATAACAGTGTCATTGTTTTATGAAATGCTTGTTTCTGGCACT
TGCCTCCCATGATTTTACAACAATTAAAACAGCCCTGTTTTTAAAACAATCATCTAGCTTACTA
GAAAGTCTGGCAGGGAGATTCTGTGCTGGTCCAGACTATTAGGGTAGATGCTGGGTTGATCTAC
AAATGGGCCACATTGGCATATCTTAGGCGATACCTCAAACACAGGGCTCTCTGTGTGGTAACAG
CAAAGTCCTCATTACAACTGATTTCTACTATGTCCAGTGTATGCAATACTTGCATATATGTGTA
TTATGGCAGTTTTTAATGAATGTTTGCATATATATTTATTTTTTCTGAAAGGGTTTTAGAGTGA
GTTTCACACTGAACTTCTGGCTTCGTGGATAATCAATGTTGATATTTTCTCTTTCACTTCAGTC
ACAGATCTTAGTAGCACTGTGAGAATTTTTAAACTAAGATTTTCATCCCGTACTTTTTAAAATT
GAAGACTTGGAGGTAGCACCATGAAAGCCTTTGTATAGTAATGAAGTTTGTATATAAATAAGAA
TGTTCAGTGACATGTTAGCGGATTTAAGTGTTTCTTACATTTTTAACTTCATGGTCATCAGTGT
AGTTTAACATCTAGTATTCCCTAATGCCAGCATGTTAACTTACTGTGCCATAAAAGCATTGAAA
ACCAACCTGTTATCATAGGACAGCTCCAGAGTTTCTGAGTGCCTTGTTATGCTGCACTTAATAC
ATCTTCCGATTGGTAAGTACACTTGTGCTGGGCAAATTTATGGCCATAAAATCAGATACATACA
CGTGGCCTTGCAGGCCGAGAGCTTTACCAATTTTCCCCTTACCCAGCACCCAAACTGACATTTC
CTGATTGCCTCAGGGACGCCTGGGAAGTCCCCTAACACCCTCGTCTCTCTCTGCTCAGGTTGCA
GAGAAGCTGCAGCACAGCCTTCCACACACCGCTCCCTCACACTGACGTACGTGCAGCTTCCGCT
CTTCCACAAACTGGCTACTCTCCCAGCCCATAGAAACGTAATCTTGTTTAGAGTGTTATCAGTT
GTTTGAACTAAAGCACAGAACTTTGAGATTTTTAAGGAATTGTTTTGTCTATGCTTACTTTGTG
GAAGTTCAGTTATCTGAATTAATAAAATATTATTTGGATTAAAAAAAAAAAAAAAAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_063282031 ⟹ XP_063138101

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	37,709,712 - 37,731,699 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001008374	(Get FASTA)	NCBI Sequence Viewer
	XP_063138101	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86553	(Get FASTA)	NCBI Sequence Viewer
	AAP69947	(Get FASTA)	NCBI Sequence Viewer
	EDM10271	(Get FASTA)	NCBI Sequence Viewer
	EDM10272	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064069
GenBank Protein	Q5RJP9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001008374 ⟸ NM_001008373
- UniProtKB:	Q5RJP9 (UniProtKB/Swiss-Prot), A6I5G3 (UniProtKB/TrEMBL), A0A8I6AEB3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVPGCNKDNVRAGCRKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEESEELNKLQA LQEKRINEEEEKKKEKSREKIKLKKKRKRSNSSTTEEDSSKQKKQKYQKKEKKKEKKNKSKKGK HHKKEKKKRKKEKRSSPNRSEVTKK hide sequence

Ensembl Acc Id:

ENSRNOP00000081440 ⟸ ENSRNOT00000115651

Ensembl Acc Id:

ENSRNOP00000091172 ⟸ ENSRNOT00000104826

Ensembl Acc Id:

ENSRNOP00000064069 ⟸ ENSRNOT00000074499

Ensembl Acc Id:

ENSRNOP00000095882 ⟸ ENSRNOT00000095129

RefSeq Acc Id:	XP_063138101 ⟸ XM_063282031
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000090851 ⟸ ENSRNOT00000103086

Ensembl Acc Id:

ENSRNOP00000102058 ⟸ ENSRNOT00000144480

Ensembl Acc Id:

ENSRNOP00000106751 ⟸ ENSRNOT00000165204

Protein Domains

CCHC-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5RJP9-F1-model_v2	AlphaFold	Q5RJP9	1-153	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305356	AgrOrtholog
BioCyc Gene	G2FUF-54545	BioCyc
Ensembl Genes	ENSRNOG00000047506	Ensembl, ENTREZGENE
	ENSRNOG00000066565	Ensembl
Ensembl Transcript	ENSRNOT00000074499	ENTREZGENE
IMAGE_CLONE	IMAGE:7303262	IMAGE-MGC_LOAD
InterPro	Znf_CCHC	UniProtKB/Swiss-Prot
KEGG Report	rno:361888	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105985	IMAGE-MGC_LOAD
NCBI Gene	361888	ENTREZGENE
PANTHER	PROTEIN SREK1IP1	UniProtKB/Swiss-Prot
	SREK1IP1 FAMILY MEMBER	UniProtKB/Swiss-Prot
Pfam	zf-CCHC_3	UniProtKB/Swiss-Prot
PhenoGen	Srek1ip1	PhenoGen
PROSITE	ZF_CCHC	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000047506	RatGTEx
	ENSRNOG00000066565	RatGTEx
UniProt	A0A8I6AEB3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B3G8_RAT	UniProtKB/TrEMBL
	A6I5G3	ENTREZGENE, UniProtKB/TrEMBL
	M0R3Z4_RAT	UniProtKB/TrEMBL
	Q5RJP9	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-01	Srek1ip1	SREK1-interacting protein 1	Sfrs12ip1	SFRS12-interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-07-22	Sfrs12ip1	SFRS12-interacting protein 1	Srek1ip1	SREK1-interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-07-13	Srek1ip1	SREK1-interacting protein 1	Sfrs12ip1	SFRS12-interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-06-13	Sfrs12ip1	SFRS12-interacting protein 1	Srek1ip1	splicing regulatory glutamine/lysine-rich protein 1 interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-04-29	Srek1ip1	splicing regulatory glutamine/lysine-rich protein 1 interacting protein 1	Sfrs12ip1	SFRS12-interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-25	Sfrs12ip1	SFRS12-interacting protein 1	P18srp	P18SRP protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	P18srp	P18SRP protein	RGD1305356	similar to RIKEN cDNA 3110031B13	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1305356	similar to RIKEN cDNA 3110031B13	RGD1305356_predicted	similar to RIKEN cDNA 3110031B13 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1305356_predicted	similar to RIKEN cDNA 3110031B13 (predicted)	LOC361888_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC361888_predicted	similar to RIKEN cDNA 3110031B13 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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