Symbol:
N4bp1
Name:
Nedd4 binding protein 1
RGD ID:
1305179
Description:
Predicted to enable RNA nuclease activity; mRNA binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including cellular response to UV; negative regulation of macromolecule metabolic process; and negative regulation of viral genome replication. Predicted to be located in cytosol and nucleolus. Predicted to be active in PML body. Orthologous to human N4BP1 (NEDD4 binding protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; acetamide.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC291921; NEDD4-binding protein 1; RGD1305179; similar to Nedd4 binding protein 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
N4BP1 (NEDD4 binding protein 1)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
N4bp1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
N4bp1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
N4BP1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
N4BP1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
N4bp1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
N4BP1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
N4BP1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
N4bp1 (NEDD4 binding protein 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
N4bp1 (NEDD4 binding protein 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
N4BP1 (NEDD4 binding protein 1)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
n4bp1 (nedd4 binding protein 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
Y24D9B.1
Alliance
DIOPT (Ensembl Compara|PANTHER)
Drosophila melanogaster (fruit fly):
CG42360
Alliance
DIOPT (Ensembl Compara|OrthoFinder)
Drosophila melanogaster (fruit fly):
CG42360
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Caenorhabditis elegans (roundworm):
Y51H4A.13
Alliance
DIOPT (Ensembl Compara|PANTHER)
Xenopus tropicalis (tropical clawed frog):
n4bp1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Related Pseudogenes:
LOC120102149
LOC120102150
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 19 36,396,082 - 36,446,835 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 19 36,396,324 - 36,446,835 (+) Ensembl GRCr8 mRatBN7.2 19 20,222,811 - 20,273,570 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 19 20,222,776 - 20,273,570 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 19 21,902,852 - 21,954,586 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 19 27,097,354 - 27,149,081 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 19 30,056,376 - 30,108,116 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 19 21,218,123 - 21,268,539 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 19 21,218,465 - 21,266,964 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 19 32,227,654 - 32,278,065 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 19 21,560,480 - 21,607,541 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 19 20,095,810 - 20,146,806 (+) NCBI Celera RGSC_v3.1 19 21,565,106 - 21,612,408 (+) NCBI Cytogenetic Map 19 p11 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
N4bp1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO N4bp1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 N4bp1 Rat 1,2-dimethylhydrazine affects expression ISO N4bp1 (Mus musculus) 6480464 1,2-Dimethylhydrazine affects the expression of N4BP1 mRNA CTD PMID:22206623 N4bp1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO N4bp1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 N4bp1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO N4bp1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 N4bp1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of N4BP1 mRNA CTD PMID:34747641 N4bp1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO N4bp1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 N4bp1 Rat 2-hydroxypropanoic acid decreases expression ISO N4BP1 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of N4BP1 mRNA CTD PMID:30851411 N4bp1 Rat 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of N4BP1 mRNA CTD PMID:30071829 N4bp1 Rat 4,4'-sulfonyldiphenol decreases methylation ISO N4bp1 (Mus musculus) 6480464 bisphenol S results in decreased methylation of N4BP1 exon CTD PMID:33297965 N4bp1 Rat 4,4'-sulfonyldiphenol affects expression ISO N4bp1 (Mus musculus) 6480464 bisphenol S affects the expression of N4BP1 mRNA CTD PMID:39298647 N4bp1 Rat 4-hydroxyphenyl retinamide increases expression ISO N4bp1 (Mus musculus) 6480464 Fenretinide results in increased expression of N4BP1 mRNA CTD PMID:28973697 N4bp1 Rat 7,12-dimethyltetraphene increases expression ISO N4bp1 (Mus musculus) 6480464 9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of N4BP1 mRNA CTD PMID:32553695 N4bp1 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of N4BP1 mRNA CTD PMID:31881176 N4bp1 Rat aflatoxin B1 increases expression ISO N4bp1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of N4BP1 mRNA CTD PMID:19770486 N4bp1 Rat aflatoxin B1 decreases methylation ISO N4BP1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of N4BP1 intron CTD PMID:30157460 N4bp1 Rat aflatoxin B1 increases methylation ISO N4BP1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of N4BP1 polyA tail CTD PMID:30157460 N4bp1 Rat all-trans-retinoic acid increases expression ISO N4BP1 (Homo sapiens) 6480464 Tretinoin results in increased expression of N4BP1 mRNA CTD PMID:33167477 N4bp1 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of N4BP1 mRNA CTD PMID:38685447 N4bp1 Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of N4BP1 mRNA CTD PMID:30779732 N4bp1 Rat arsenite(3-) multiple interactions ISO N4BP1 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to N4BP1 mRNA] CTD PMID:32406909 N4bp1 Rat arsenous acid increases expression ISO N4BP1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of N4BP1 mRNA CTD PMID:15761015 N4bp1 Rat benzo[a]pyrene increases expression ISO N4bp1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of N4BP1 mRNA CTD PMID:19770486 N4bp1 Rat benzo[a]pyrene increases methylation ISO N4BP1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of N4BP1 3' UTR CTD PMID:27901495 N4bp1 Rat benzo[a]pyrene affects methylation ISO N4BP1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of N4BP1 promoter CTD PMID:27901495 N4bp1 Rat benzo[a]pyrene decreases expression ISO N4BP1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of N4BP1 mRNA CTD PMID:22316170 N4bp1 Rat benzo[a]pyrene diol epoxide I decreases expression ISO N4BP1 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of N4BP1 mRNA CTD PMID:19150397 N4bp1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO N4bp1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of N4BP1 mRNA CTD PMID:33754040 N4bp1 Rat bisphenol A decreases expression ISO N4BP1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of N4BP1 mRNA CTD PMID:20678512 N4bp1 Rat bisphenol A decreases methylation ISO N4BP1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of N4BP1 gene CTD PMID:31601247 N4bp1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of N4BP1 mRNA CTD PMID:25181051|PMID:30816183|PMID:32145629 N4bp1 Rat Butylbenzyl phthalate increases methylation ISO N4bp1 (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of N4BP1 intron CTD PMID:28392331 N4bp1 Rat cadmium atom multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of N4BP1 more ... CTD PMID:35301059 N4bp1 Rat cadmium dichloride multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of N4BP1 more ... CTD PMID:35301059 N4bp1 Rat caffeine decreases phosphorylation ISO N4BP1 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of N4BP1 protein CTD PMID:35688186 N4bp1 Rat CGP 52608 multiple interactions ISO N4BP1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to N4BP1 gene] CTD PMID:28238834 N4bp1 Rat chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of N4BP1 mRNA CTD PMID:23125180 N4bp1 Rat chlorpyrifos increases expression ISO N4bp1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of N4BP1 mRNA CTD PMID:37019170 N4bp1 Rat cobalt dichloride increases expression ISO N4BP1 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of N4BP1 mRNA CTD PMID:19376846 N4bp1 Rat coumarin increases phosphorylation ISO N4BP1 (Homo sapiens) 6480464 coumarin results in increased phosphorylation of N4BP1 protein CTD PMID:35688186 N4bp1 Rat coumestrol decreases expression ISO N4BP1 (Homo sapiens) 6480464 Coumestrol results in decreased expression of N4BP1 mRNA CTD PMID:19167446 N4bp1 Rat coumestrol multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of N4BP1 mRNA CTD PMID:19167446 N4bp1 Rat crotonaldehyde decreases expression ISO N4BP1 (Homo sapiens) 6480464 2-butenal results in decreased expression of N4BP1 mRNA CTD PMID:20471460 N4bp1 Rat diarsenic trioxide increases expression ISO N4BP1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of N4BP1 mRNA CTD PMID:15761015 N4bp1 Rat Dibutyl phosphate affects expression ISO N4BP1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of N4BP1 mRNA CTD PMID:37042841 N4bp1 Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of N4BP1 mRNA CTD PMID:25152437 N4bp1 Rat dorsomorphin multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 N4bp1 Rat doxorubicin decreases expression ISO N4BP1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of N4BP1 mRNA CTD PMID:29803840 N4bp1 Rat Enterolactone multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of N4BP1 mRNA CTD PMID:19167446 N4bp1 Rat ethanol affects splicing ISO N4bp1 (Mus musculus) 6480464 Ethanol affects the splicing of N4BP1 mRNA CTD PMID:30319688 N4bp1 Rat ethyl methanesulfonate increases expression ISO N4BP1 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of N4BP1 mRNA CTD PMID:23649840 N4bp1 Rat formaldehyde decreases expression ISO N4BP1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of N4BP1 mRNA CTD PMID:20655997 N4bp1 Rat FR900359 affects phosphorylation ISO N4BP1 (Homo sapiens) 6480464 FR900359 affects the phosphorylation of N4BP1 protein CTD PMID:37730182 N4bp1 Rat irinotecan decreases expression ISO N4BP1 (Homo sapiens) 6480464 Irinotecan analog results in decreased expression of N4BP1 mRNA CTD PMID:18927307 N4bp1 Rat methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of N4BP1 mRNA CTD PMID:19564919 N4bp1 Rat methyl methanesulfonate increases expression ISO N4BP1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of N4BP1 mRNA CTD PMID:23649840 N4bp1 Rat methylmercury chloride decreases expression ISO N4BP1 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of N4BP1 mRNA CTD PMID:28001369 N4bp1 Rat mono(2-ethylhexyl) phthalate increases expression ISO N4bp1 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of N4BP1 mRNA CTD PMID:20463053 N4bp1 Rat nickel atom increases expression ISO N4BP1 (Homo sapiens) 6480464 Nickel results in increased expression of N4BP1 mRNA CTD PMID:24768652|PMID:25583101 N4bp1 Rat PCB138 multiple interactions ISO N4bp1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 N4bp1 Rat pentachlorophenol increases expression ISO N4bp1 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of N4BP1 mRNA CTD PMID:23892564 N4bp1 Rat PhIP decreases expression ISO N4BP1 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of N4BP1 mRNA CTD PMID:20816883 N4bp1 Rat pregnenolone 16alpha-carbonitrile decreases expression ISO N4bp1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of N4BP1 mRNA CTD PMID:22698814 N4bp1 Rat rac-lactic acid decreases expression ISO N4BP1 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of N4BP1 mRNA CTD PMID:30851411 N4bp1 Rat resveratrol decreases expression ISO N4BP1 (Homo sapiens) 6480464 resveratrol results in decreased expression of N4BP1 mRNA CTD PMID:19167446 N4bp1 Rat SB 431542 multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 N4bp1 Rat Soman increases expression EXP 6480464 Soman results in increased expression of N4BP1 mRNA CTD PMID:19281266 N4bp1 Rat sunitinib increases expression ISO N4BP1 (Homo sapiens) 6480464 Sunitinib results in increased expression of N4BP1 mRNA CTD PMID:31533062 N4bp1 Rat tert-butyl hydroperoxide decreases expression ISO N4BP1 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of N4BP1 mRNA CTD PMID:15336504 N4bp1 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of N4BP1 mRNA CTD PMID:31150632 N4bp1 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of N4BP1 mRNA CTD PMID:23411599|PMID:34492290 N4bp1 Rat trichostatin A decreases expression ISO N4BP1 (Homo sapiens) 6480464 trichostatin A results in decreased expression of N4BP1 mRNA CTD PMID:24935251|PMID:26272509 N4bp1 Rat trichostatin A multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 N4bp1 Rat trimellitic anhydride increases expression ISO N4bp1 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of N4BP1 mRNA CTD PMID:19042947 N4bp1 Rat triphenyl phosphate affects expression ISO N4BP1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of N4BP1 mRNA CTD PMID:37042841 N4bp1 Rat troglitazone decreases expression ISO N4bp1 (Mus musculus) 6480464 troglitazone results in decreased expression of N4BP1 mRNA CTD PMID:28973697 N4bp1 Rat tungsten decreases expression ISO N4bp1 (Mus musculus) 6480464 Tungsten results in decreased expression of N4BP1 mRNA CTD PMID:30912803 N4bp1 Rat valproic acid decreases expression ISO N4BP1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of N4BP1 mRNA CTD PMID:26272509 N4bp1 Rat valproic acid multiple interactions ISO N4BP1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 N4bp1 Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of N4BP1 mRNA CTD PMID:23034163 N4bp1 Rat vinclozolin decreases methylation EXP 6480464 vinclozolin results in decreased methylation of N4BP1 gene CTD PMID:31079544 N4bp1 Rat vitamin E decreases expression ISO N4BP1 (Homo sapiens) 6480464 Vitamin E results in decreased expression of N4BP1 mRNA CTD PMID:19244175