Rhbdf1 (rhomboid 5 homolog 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Rhbdf1 (rhomboid 5 homolog 1) Rattus norvegicus
Analyze
Symbol: Rhbdf1
Name: rhomboid 5 homolog 1
RGD ID: 1305075
Description: Predicted to enable growth factor binding activity. Predicted to be involved in several processes, including negative regulation of protein secretion; regulation of epidermal growth factor receptor signaling pathway; and regulation of proteasomal protein catabolic process. Predicted to be located in Golgi membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human RHBDF1 (rhomboid 5 homolog 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inactive rhomboid protein 1; iRhom1; LOC303008; MGC124815; rhomboid 5 homolog 1 (Drosophila); rhomboid family 1; rhomboid family 1 (Drosophila); rhomboid family member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,911,282 - 15,924,214 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,911,308 - 15,924,214 (+)EnsemblGRCr8
mRatBN7.21015,406,832 - 15,419,765 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,406,859 - 15,419,763 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1020,152,893 - 20,165,784 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,641,781 - 19,654,677 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01015,134,664 - 15,147,558 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,672,370 - 15,685,285 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,672,382 - 15,685,284 (+)Ensemblrn6Rnor6.0
Rnor_5.01015,567,515 - 15,580,428 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41015,653,948 - 15,666,851 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1015,074,361 - 15,087,252 (+)NCBICelera
RGSC_v3.11015,661,089 - 15,667,673 (+)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
estrone  (ISO)
ethanol  (ISO)
fenthion  (ISO)
fenvalerate  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
indometacin  (ISO)
mestranol  (ISO)
methamphetamine  (EXP)
methidathion  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
endomembrane system  (IEA)
endoplasmic reticulum membrane  (IBA,IEA,ISO,ISS)
Golgi membrane  (IEA,ISO,ISS)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18832597   PMID:21439629  


Genomics

Comparative Map Data
Rhbdf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,911,282 - 15,924,214 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1015,911,308 - 15,924,214 (+)EnsemblGRCr8
mRatBN7.21015,406,832 - 15,419,765 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,406,859 - 15,419,763 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1020,152,893 - 20,165,784 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,641,781 - 19,654,677 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01015,134,664 - 15,147,558 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,672,370 - 15,685,285 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,672,382 - 15,685,284 (+)Ensemblrn6Rnor6.0
Rnor_5.01015,567,515 - 15,580,428 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41015,653,948 - 15,666,851 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1015,074,361 - 15,087,252 (+)NCBICelera
RGSC_v3.11015,661,089 - 15,667,673 (+)NCBI
Cytogenetic Map10q12NCBI
RHBDF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381658,059 - 76,360 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1658,058 - 78,176 (-)Ensemblhg38GRCh38
GRCh3716108,058 - 122,629 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361648,058 - 62,591 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341648,058 - 62,591NCBI
Celera16309,954 - 324,535 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef1626,451 - 41,032 (-)NCBIHuRef
CHM1_116107,996 - 122,575 (-)NCBICHM1_1
T2T-CHM13v2.01651,596 - 69,903 (-)NCBIT2T-CHM13v2.0
Rhbdf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,159,585 - 32,172,339 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,159,585 - 32,172,300 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381132,209,585 - 32,222,331 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,209,585 - 32,222,300 (-)Ensemblmm10GRCm38
MGSCv371132,109,585 - 32,122,293 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361132,109,585 - 32,122,238 (-)NCBIMGSCv36mm8
Celera1134,626,680 - 34,639,569 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.83NCBI
Rhbdf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,078,864 - 17,098,999 (+)Ensembl
ChiLan1.0NW_00495544217,090,962 - 17,098,068 (+)NCBIChiLan1.0ChiLan1.0
RHBDF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218273,273 - 291,700 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,065,373 - 4,083,718 (-)NCBINHGRI_mPanPan1
PanPan1.11649,031 - 57,211 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1649,031 - 57,222 (-)EnsemblpanPan2panpan1.1
RHBDF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,394,654 - 40,413,619 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,395,517 - 40,413,606 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha641,652,775 - 41,676,636 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0640,732,787 - 40,756,647 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,739,139 - 40,756,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1640,420,352 - 40,444,203 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,381,279 - 40,405,130 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,860,455 - 40,884,315 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rhbdf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,705,206 - 112,712,074 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501803,005 - 813,367 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936501802,728 - 810,375 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHBDF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,560,915 - 41,567,593 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1341,548,440 - 41,567,596 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,869,445 - 40,888,436 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RHBDF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1514,935 - 34,991 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl513,071 - 21,883 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606831,194,498 - 31,209,982 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rhbdf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913937,484 - 954,428 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624913937,484 - 954,458 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rhbdf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v193,661,662 - 3,674,489 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rhbdf1
67 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:95
Interacting mature miRNAs:101
Transcripts:ENSRNOT00000027965
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101576223019737486Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
REN94523  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21015,418,643 - 15,418,890 (+)MAPPERmRatBN7.2
Rnor_6.01015,684,165 - 15,684,411NCBIRnor6.0
Rnor_5.01015,579,308 - 15,579,554UniSTSRnor5.0
RGSC_v3.41015,665,731 - 15,665,977UniSTSRGSC3.4
Celera1015,086,132 - 15,086,378UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 88 59 6 352 188 11 138 81 92 31 16 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001030034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000027965   ⟹   ENSRNOP00000027965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1015,911,311 - 15,924,214 (+)Ensembl
mRatBN7.2 Ensembl1015,406,859 - 15,419,763 (+)Ensembl
Rnor_6.0 Ensembl1015,672,382 - 15,685,284 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000145512   ⟹   ENSRNOP00000112746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1015,911,308 - 15,924,213 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148107   ⟹   ENSRNOP00000108625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1015,911,311 - 15,924,214 (+)Ensembl
RefSeq Acc Id: NM_001030034   ⟹   NP_001025205
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,911,311 - 15,924,214 (+)NCBI
mRatBN7.21015,406,859 - 15,419,764 (+)NCBI
Rnor_6.01015,672,382 - 15,685,285 (+)NCBI
Rnor_5.01015,567,515 - 15,580,428 (+)NCBI
RGSC_v3.41015,653,948 - 15,666,851 (+)RGD
Celera1015,074,361 - 15,087,252 (+)RGD
Sequence:
RefSeq Acc Id: XM_039085877   ⟹   XP_038941805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,911,282 - 15,924,214 (+)NCBI
mRatBN7.21015,406,832 - 15,419,764 (+)NCBI
RefSeq Acc Id: XM_039085878   ⟹   XP_038941806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,911,288 - 15,924,214 (+)NCBI
mRatBN7.21015,406,832 - 15,419,764 (+)NCBI
RefSeq Acc Id: XM_039085879   ⟹   XP_038941807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,911,305 - 15,924,214 (+)NCBI
mRatBN7.21015,406,848 - 15,419,765 (+)NCBI
RefSeq Acc Id: XM_039085880   ⟹   XP_038941808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,912,318 - 15,924,214 (+)NCBI
mRatBN7.21015,407,690 - 15,419,764 (+)NCBI
RefSeq Acc Id: XM_039085881   ⟹   XP_038941809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,911,282 - 15,924,214 (+)NCBI
mRatBN7.21015,406,832 - 15,419,764 (+)NCBI
RefSeq Acc Id: XM_063268948   ⟹   XP_063125018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,911,288 - 15,924,214 (+)NCBI
RefSeq Acc Id: XM_063268949   ⟹   XP_063125019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,911,316 - 15,924,214 (+)NCBI
RefSeq Acc Id: XM_063268950   ⟹   XP_063125020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,912,319 - 15,924,214 (+)NCBI
RefSeq Acc Id: XM_063268951   ⟹   XP_063125021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,912,318 - 15,924,214 (+)NCBI
RefSeq Acc Id: NP_001025205   ⟸   NM_001030034
- UniProtKB: Q499S9 (UniProtKB/Swiss-Prot),   A6HDB3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027965   ⟸   ENSRNOT00000027965
RefSeq Acc Id: XP_038941806   ⟸   XM_039085878
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941805   ⟸   XM_039085877
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941809   ⟸   XM_039085881
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941807   ⟸   XM_039085879
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941808   ⟸   XM_039085880
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063125018   ⟸   XM_063268948
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063125019   ⟸   XM_063268949
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063125021   ⟸   XM_063268951
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063125020   ⟸   XM_063268950
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000112746   ⟸   ENSRNOT00000145512
Ensembl Acc Id: ENSRNOP00000108625   ⟸   ENSRNOT00000148107
Protein Domains
Inactive rhomboid protein 1/2 N-terminal   Peptidase S54 rhomboid

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q499S9-F1-model_v2 AlphaFold Q499S9 1-856 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697081
Promoter ID:EPDNEW_R7604
Type:initiation region
Name:Rhbdf1_1
Description:rhomboid 5 homolog 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01015,672,379 - 15,672,439EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305075 AgrOrtholog
BioCyc Gene G2FUF-25697 BioCyc
Ensembl Genes ENSRNOG00000020594 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027965 ENTREZGENE
  ENSRNOT00000027965.5 UniProtKB/Swiss-Prot
  ENSRNOT00000145512 ENTREZGENE
Gene3D-CATH 1.20.1540.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7933232 IMAGE-MGC_LOAD
InterPro Inactive_Rhomboid UniProtKB/Swiss-Prot
  Peptidase_S54_rhomboid_dom UniProtKB/Swiss-Prot
  Rhomboid-like_sf UniProtKB/Swiss-Prot
  Rhomboid_SP UniProtKB/Swiss-Prot
KEGG Report rno:303008 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124815 IMAGE-MGC_LOAD
NCBI Gene 303008 ENTREZGENE
PANTHER INACTIVE RHOMBOID PROTEIN UniProtKB/Swiss-Prot
  INACTIVE RHOMBOID PROTEIN 1 UniProtKB/Swiss-Prot
Pfam Rhomboid UniProtKB/Swiss-Prot
  Rhomboid_SP UniProtKB/Swiss-Prot
PhenoGen Rhbdf1 PhenoGen
RatGTEx ENSRNOG00000020594 RatGTEx
Superfamily-SCOP SSF144091 UniProtKB/Swiss-Prot
UniProt A0ABK0LP41_RAT UniProtKB/TrEMBL
  A0ABK0LRQ2_RAT UniProtKB/TrEMBL
  A6HDB3 ENTREZGENE, UniProtKB/TrEMBL
  Q499S9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Rhbdf1  rhomboid 5 homolog 1  Rhbdf1  rhomboid 5 homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-04 Rhbdf1  rhomboid 5 homolog 1 (Drosophila)  Rhbdf1  rhomboid family 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Rhbdf1  rhomboid family 1 (Drosophila)  Rhbdf1_predicted  rhomboid family 1 (Drosophila) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Rhbdf1_predicted  rhomboid family 1 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED