Sec61b (SEC61 translocon subunit beta) - Rat Genome Database

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Gene: Sec61b (SEC61 translocon subunit beta) Rattus norvegicus
Analyze
Symbol: Sec61b
Name: SEC61 translocon subunit beta
RGD ID: 1304997
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be part of Sec61 translocon complex. Predicted to be active in membrane. Orthologous to human SEC61B (SEC61 translocon subunit beta); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; phagocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC298068; protein transport protein Sec61 subunit beta; Sec61 beta subunit; Sec61 translocon beta subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8566,569,184 - 66,577,394 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl566,569,196 - 66,580,028 (+)EnsemblGRCr8
mRatBN7.2561,773,594 - 61,781,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl561,773,594 - 61,781,804 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx563,745,475 - 63,753,662 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0565,564,777 - 65,572,964 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0565,534,249 - 65,542,436 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd566,702,773 - 66,711,048 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive568,274,965 - 68,283,240 (+)NCBILyon_Normotensive
Lyon_Hypertensive567,593,303 - 67,601,578 (+)NCBILyon_Hypertensive
F344_StmMcwi561,461,707 - 61,469,982 (+)NCBIF344_StmMcwi
Rnor_6.0563,192,322 - 63,200,532 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl563,192,298 - 63,200,508 (+)Ensemblrn6Rnor6.0
Rnor_5.0567,711,881 - 67,720,091 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4564,096,869 - 64,105,082 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera565,811,176 - 65,819,388 (-)NCBICelera
RGSC_v3.1564,101,911 - 64,110,117 (+)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
benzatropine  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
clozapine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
deoxynivalenol  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
genistein  (ISO)
glafenine  (EXP)
inulin  (ISO)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
nickel sulfate  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
propiconazole  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sunitinib  (ISO)
tetrachloroethene  (ISO)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
Torularhodin  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment. Greenfield JJ and High S, J Cell Sci 1999 May;112 ( Pt 10):1477-86.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8945469   PMID:11408579   PMID:12477932   PMID:16705175   PMID:17215517   PMID:18555783   PMID:19602593   PMID:22375059   PMID:22658674   PMID:23093945   PMID:23439682   PMID:27044890  
PMID:31505169  


Genomics

Comparative Map Data
Sec61b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8566,569,184 - 66,577,394 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl566,569,196 - 66,580,028 (+)EnsemblGRCr8
mRatBN7.2561,773,594 - 61,781,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl561,773,594 - 61,781,804 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx563,745,475 - 63,753,662 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0565,564,777 - 65,572,964 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0565,534,249 - 65,542,436 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd566,702,773 - 66,711,048 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive568,274,965 - 68,283,240 (+)NCBILyon_Normotensive
Lyon_Hypertensive567,593,303 - 67,601,578 (+)NCBILyon_Hypertensive
F344_StmMcwi561,461,707 - 61,469,982 (+)NCBIF344_StmMcwi
Rnor_6.0563,192,322 - 63,200,532 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl563,192,298 - 63,200,508 (+)Ensemblrn6Rnor6.0
Rnor_5.0567,711,881 - 67,720,091 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4564,096,869 - 64,105,082 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera565,811,176 - 65,819,388 (-)NCBICelera
RGSC_v3.1564,101,911 - 64,110,117 (+)NCBI
Cytogenetic Map5q22NCBI
SEC61B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38999,222,282 - 99,230,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl999,222,064 - 99,230,615 (+)Ensemblhg38GRCh38
GRCh379101,984,564 - 101,992,897 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369101,024,391 - 101,032,722 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34999,064,124 - 99,072,455NCBI
Celera972,498,433 - 72,506,764 (+)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef971,583,219 - 71,591,550 (+)NCBIHuRef
CHM1_19102,131,019 - 102,139,349 (+)NCBICHM1_1
T2T-CHM13v2.09111,393,986 - 111,402,319 (+)NCBIT2T-CHM13v2.0
Sec61b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39447,474,661 - 47,483,233 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl447,474,658 - 47,483,242 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38447,474,661 - 47,483,233 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl447,474,658 - 47,483,242 (+)Ensemblmm10GRCm38
MGSCv37447,487,533 - 47,496,105 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36447,495,761 - 47,504,333 (+)NCBIMGSCv36mm8
Celera447,497,246 - 47,505,818 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.03NCBI
Sec61b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541926,410,911 - 26,423,718 (-)Ensembl
ChiLan1.0NW_00495541926,414,891 - 26,423,260 (-)NCBIChiLan1.0ChiLan1.0
SEC61B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21140,227,057 - 40,235,424 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1940,229,432 - 40,237,799 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0970,312,061 - 70,320,448 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1998,430,774 - 98,439,105 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl998,431,059 - 98,438,914 (+)EnsemblpanPan2panpan1.1
SEC61B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11156,279,564 - 56,298,593 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1156,251,636 - 56,286,291 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1154,710,432 - 54,716,934 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01157,387,547 - 57,394,054 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1157,359,606 - 57,407,112 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11155,892,012 - 55,898,512 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01155,916,992 - 55,923,491 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01156,616,366 - 56,622,875 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sec61b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947171,183,406 - 171,191,834 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365247,731,058 - 7,740,310 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365247,731,033 - 7,739,410 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC61B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1240,985,162 - 240,992,976 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11240,985,173 - 240,991,820 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21269,216,031 - 269,222,679 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEC61B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11240,194,243 - 40,202,474 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1240,194,301 - 40,202,441 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660352,327,848 - 2,336,120 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec61b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248251,762,734 - 1,771,233 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248251,762,735 - 1,771,271 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sec61b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11100,563,686 - 100,571,913 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sec61b
17 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:160
Count of miRNA genes:122
Interacting mature miRNAs:140
Transcripts:ENSRNOT00000008329
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000008329   ⟹   ENSRNOP00000008329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl561,773,594 - 61,781,804 (+)Ensembl
Rnor_6.0 Ensembl563,192,298 - 63,200,508 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000154630   ⟹   ENSRNOP00000110391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl566,569,196 - 66,580,028 (+)Ensembl
RefSeq Acc Id: NM_001106654   ⟹   NP_001100124
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8566,569,184 - 66,577,394 (+)NCBI
mRatBN7.2561,773,594 - 61,781,804 (+)NCBI
Dahl_SR_JrHsd566,702,773 - 66,711,048 (+)NCBI
Lyon_Normotensive568,274,965 - 68,283,240 (+)NCBI
Lyon_Hypertensive567,593,303 - 67,601,578 (+)NCBI
F344_StmMcwi561,461,707 - 61,469,982 (+)NCBI
Rnor_6.0563,192,322 - 63,200,532 (+)NCBI
Rnor_5.0567,711,881 - 67,720,091 (+)NCBI
RGSC_v3.4564,096,869 - 64,105,082 (+)RGD
Celera565,811,176 - 65,819,388 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100124 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI67110 (Get FASTA)   NCBI Sequence Viewer  
  EDL78204 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000110391
  ENSRNOP00000110391.1
RefSeq Acc Id: NP_001100124   ⟸   NM_001106654
- UniProtKB: B2RZD1 (UniProtKB/TrEMBL),   F7F271 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008329   ⟸   ENSRNOT00000008329
Ensembl Acc Id: ENSRNOP00000110391   ⟸   ENSRNOT00000154630

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RZD1-F1-model_v2 AlphaFold B2RZD1 1-96 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693722
Promoter ID:EPDNEW_R4246
Type:initiation region
Name:Sec61b_1
Description:Sec61 translocon beta subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0563,192,334 - 63,192,394EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304997 AgrOrtholog
BioCyc Gene G2FUF-41377 BioCyc
Ensembl Genes ENSRNOG00000006345 Ensembl
  ENSRNOG00000086213 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000154630 ENTREZGENE
  ENSRNOT00000154630.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6887572 IMAGE-MGC_LOAD
InterPro Sec61-beta/Sbh UniProtKB/TrEMBL
  Sec61_beta_euk UniProtKB/TrEMBL
KEGG Report rno:298068 UniProtKB/TrEMBL
MGC_CLONE MGC:189573 IMAGE-MGC_LOAD
NCBI Gene 298068 ENTREZGENE
PANTHER PTHR13509 UniProtKB/TrEMBL
Pfam Sec61_beta UniProtKB/TrEMBL
PhenoGen Sec61b PhenoGen
PIRSF Sec61_beta_euk UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006345 RatGTEx
  ENSRNOG00000086213 RatGTEx
UniProt A0ABK0LXI6_RAT UniProtKB/TrEMBL
  B2RZD1 ENTREZGENE
  F7F271 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Sec61b  SEC61 translocon subunit beta  Sec61b  Sec61 translocon beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-08-11 Sec61b  Sec61 translocon beta subunit  Sec61b  Sec61 beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sec61b  Sec61 beta subunit   Sec61b_predicted  Sec61 beta subunit (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sec61b_predicted  Sec61 beta subunit (predicted)      Symbol and Name status set to approved 70820 APPROVED