Lpin2 (lipin 2) - Rat Genome Database

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Gene: Lpin2 (lipin 2) Rattus norvegicus
Analyze
Symbol: Lpin2
Name: lipin 2
RGD ID: 1304588
Description: Predicted to enable phosphatidate phosphatase activity and transcription coactivator activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; positive regulation of transcription by RNA polymerase II; and triglyceride biosynthetic process. Predicted to be active in cytosol; endoplasmic reticulum membrane; and nucleus. Human ortholog(s) of this gene implicated in chronic recurrent multifocal osteomyelitis. Orthologous to human LPIN2 (lipin 2); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC316737; phosphatidate phosphatase LPIN2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89118,529,988 - 118,604,796 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9118,529,943 - 118,604,796 (+)EnsemblGRCr8
mRatBN7.29111,083,378 - 111,158,193 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9111,083,745 - 111,158,193 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9119,477,330 - 119,551,212 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09124,606,892 - 124,680,761 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09122,943,299 - 123,017,170 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09119,517,101 - 119,591,533 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9119,517,101 - 119,591,533 (+)Ensemblrn6Rnor6.0
Rnor_5.09118,970,173 - 119,045,052 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49110,380,692 - 110,484,329 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9108,213,668 - 108,287,163 (+)NCBICelera
RGSC_v3.19110,556,496 - 110,662,140 (+)NCBI
Cytogenetic Map9q38NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
GW 4064  (ISO)
hexadecanoic acid  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indole-3-methanol  (EXP)
lovastatin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
metformin  (EXP)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
microcystin-LR  (ISO)
N-methylformamide  (ISO)
obeticholic acid  (ISO)
okadaic acid  (ISO)
oleic acid  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rotenone  (EXP)
Salinomycin  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (EXP,ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA,ISO)
endoplasmic reticulum membrane  (IBA,IEA,ISO)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17158099   PMID:18694939   PMID:19717560   PMID:23505321  


Genomics

Comparative Map Data
Lpin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89118,529,988 - 118,604,796 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9118,529,943 - 118,604,796 (+)EnsemblGRCr8
mRatBN7.29111,083,378 - 111,158,193 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9111,083,745 - 111,158,193 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9119,477,330 - 119,551,212 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09124,606,892 - 124,680,761 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09122,943,299 - 123,017,170 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09119,517,101 - 119,591,533 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9119,517,101 - 119,591,533 (+)Ensemblrn6Rnor6.0
Rnor_5.09118,970,173 - 119,045,052 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49110,380,692 - 110,484,329 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9108,213,668 - 108,287,163 (+)NCBICelera
RGSC_v3.19110,556,496 - 110,662,140 (+)NCBI
Cytogenetic Map9q38NCBI
LPIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38182,916,994 - 3,013,144 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl182,885,296 - 3,013,345 (-)Ensemblhg38GRCh38
GRCh37182,916,992 - 3,013,142 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36182,906,992 - 3,001,945 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34182,906,992 - 3,001,945NCBI
Celera182,792,438 - 2,887,255 (-)NCBICelera
Cytogenetic Map18p11.31NCBI
HuRef182,878,273 - 2,973,028 (-)NCBIHuRef
CHM1_1182,916,356 - 3,011,234 (-)NCBICHM1_1
T2T-CHM13v2.0183,072,495 - 3,168,675 (-)NCBIT2T-CHM13v2.0
Lpin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391771,490,527 - 71,556,813 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1771,489,555 - 71,556,812 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381771,183,532 - 71,249,818 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1771,182,560 - 71,249,817 (+)Ensemblmm10GRCm38
MGSCv371771,533,318 - 71,599,158 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361771,109,525 - 71,153,086 (+)NCBIMGSCv36mm8
Celera1775,451,935 - 75,517,734 (+)NCBICelera
Cytogenetic Map17E1.3NCBI
cM Map1741.87NCBI
Lpin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554027,472,538 - 7,504,231 (+)Ensembl
ChiLan1.0NW_0049554027,457,408 - 7,505,829 (+)NCBIChiLan1.0ChiLan1.0
LPIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21735,434,206 - 35,530,403 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11821,126,608 - 21,222,995 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01811,270,941 - 11,367,312 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11813,586,801 - 13,675,170 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1813,608,883 - 13,675,165 (+)EnsemblpanPan2panpan1.1
LPIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1769,583,386 - 69,664,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl769,580,736 - 69,673,899 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha769,038,655 - 69,119,523 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0769,645,593 - 69,726,459 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl769,645,597 - 69,726,438 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1769,327,908 - 69,408,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0769,347,982 - 69,428,812 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0769,645,434 - 69,726,575 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lpin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494465,935,673 - 65,990,966 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366721,568,732 - 1,602,931 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366721,550,865 - 1,606,268 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LPIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6103,687,743 - 103,728,148 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16103,625,725 - 103,728,151 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap6qNCBI
LPIN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11862,152,837 - 62,265,992 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1862,177,246 - 62,236,593 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605037,029,173 - 37,122,493 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lpin2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477013,159,903 - 13,203,643 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477013,158,111 - 13,200,818 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lpin2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14180,645,604 - 180,719,326 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1221
Count of miRNA genes:341
Interacting mature miRNAs:468
Transcripts:ENSRNOT00000020476
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat

Markers in Region
Lpin2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29111,155,134 - 111,155,259 (+)MAPPERmRatBN7.2
Rnor_6.09119,588,475 - 119,588,599NCBIRnor6.0
Rnor_5.09119,041,994 - 119,042,118UniSTSRnor5.0
RGSC_v3.49110,452,617 - 110,452,741UniSTSRGSC3.4
Celera9108,284,105 - 108,284,229UniSTS
Cytogenetic Map9q38UniSTS
RH130840  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29111,160,755 - 111,160,952 (+)MAPPERmRatBN7.2
Rnor_6.09119,594,096 - 119,594,292NCBIRnor6.0
Rnor_5.09119,047,615 - 119,047,811UniSTSRnor5.0
RGSC_v3.49110,458,112 - 110,458,308UniSTSRGSC3.4
Celera9108,289,727 - 108,289,923UniSTS
RH 3.4 Map9868.3UniSTS
Cytogenetic Map9q38UniSTS
BF393806  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29111,120,278 - 111,120,494 (+)MAPPERmRatBN7.2
Rnor_6.09119,553,643 - 119,553,858NCBIRnor6.0
Rnor_5.09119,006,855 - 119,007,070UniSTSRnor5.0
RGSC_v3.49110,417,771 - 110,417,986UniSTSRGSC3.4
Celera9108,249,243 - 108,249,458UniSTS
RH 3.4 Map9871.0UniSTS
Cytogenetic Map9q38UniSTS
RH139603  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29111,156,362 - 111,156,562 (+)MAPPERmRatBN7.2
Rnor_6.09119,589,703 - 119,589,902NCBIRnor6.0
Rnor_5.09119,043,222 - 119,043,421UniSTSRnor5.0
RGSC_v3.49110,454,449 - 110,454,648UniSTSRGSC3.4
Celera9108,285,333 - 108,285,532UniSTS
RH 3.4 Map9869.2UniSTS
Cytogenetic Map9q38UniSTS
RH140462  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29111,156,397 - 111,156,562 (+)MAPPERmRatBN7.2
Rnor_6.09119,589,738 - 119,589,902NCBIRnor6.0
Rnor_5.09119,043,257 - 119,043,421UniSTSRnor5.0
RGSC_v3.49110,454,484 - 110,454,648UniSTSRGSC3.4
Celera9108,285,368 - 108,285,532UniSTS
Cytogenetic Map9q38UniSTS
RH140803  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29111,157,865 - 111,157,987 (+)MAPPERmRatBN7.2
Rnor_6.09119,591,206 - 119,591,327NCBIRnor6.0
Rnor_5.09119,044,725 - 119,044,846UniSTSRnor5.0
Celera9108,286,836 - 108,286,957UniSTS
RH 3.4 Map9871.1UniSTS
Cytogenetic Map9q38UniSTS
AW529903  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29111,137,486 - 111,137,637 (+)MAPPERmRatBN7.2
Rnor_6.09119,570,848 - 119,570,998NCBIRnor6.0
Rnor_5.09119,024,060 - 119,024,210UniSTSRnor5.0
RGSC_v3.49110,434,983 - 110,435,133UniSTSRGSC3.4
Celera9108,266,454 - 108,266,604UniSTS
RH 3.4 Map9867.1UniSTS
Cytogenetic Map9q38UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020476   ⟹   ENSRNOP00000020476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9118,529,943 - 118,604,794 (+)Ensembl
mRatBN7.2 Ensembl9111,083,745 - 111,158,193 (+)Ensembl
Rnor_6.0 Ensembl9119,517,101 - 119,591,533 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082005   ⟹   ENSRNOP00000070532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9118,555,672 - 118,604,796 (+)Ensembl
mRatBN7.2 Ensembl9111,109,011 - 111,158,193 (+)Ensembl
Rnor_6.0 Ensembl9119,542,328 - 119,588,715 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095983   ⟹   ENSRNOP00000078237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9118,566,426 - 118,602,086 (+)Ensembl
mRatBN7.2 Ensembl9111,119,702 - 111,158,193 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113074   ⟹   ENSRNOP00000092729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9118,529,943 - 118,604,794 (+)Ensembl
mRatBN7.2 Ensembl9111,083,745 - 111,158,193 (+)Ensembl
RefSeq Acc Id: NM_001108236   ⟹   NP_001101706
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,530,355 - 118,604,796 (+)NCBI
mRatBN7.29111,083,745 - 111,158,193 (+)NCBI
Rnor_6.09119,517,101 - 119,591,533 (+)NCBI
Rnor_5.09118,970,173 - 119,045,052 (+)NCBI
RGSC_v3.49110,380,692 - 110,484,329 (+)RGD
Celera9108,213,668 - 108,287,163 (+)RGD
Sequence:
RefSeq Acc Id: XM_006245662   ⟹   XP_006245724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,553,331 - 118,604,796 (+)NCBI
mRatBN7.29111,105,693 - 111,158,193 (+)NCBI
Rnor_6.09119,540,193 - 119,591,533 (+)NCBI
Rnor_5.09118,970,173 - 119,045,052 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245663   ⟹   XP_006245725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,553,331 - 118,604,796 (+)NCBI
mRatBN7.29111,105,693 - 111,158,193 (+)NCBI
Rnor_6.09119,540,192 - 119,591,533 (+)NCBI
Rnor_5.09118,970,173 - 119,045,052 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245664   ⟹   XP_006245726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,565,874 - 118,604,796 (+)NCBI
mRatBN7.29111,119,398 - 111,158,193 (+)NCBI
Rnor_6.09119,552,636 - 119,591,533 (+)NCBI
Rnor_5.09118,970,173 - 119,045,052 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245665   ⟹   XP_006245727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,553,331 - 118,604,796 (+)NCBI
mRatBN7.29111,105,693 - 111,158,193 (+)NCBI
Rnor_6.09119,540,192 - 119,591,533 (+)NCBI
Rnor_5.09118,970,173 - 119,045,052 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083795   ⟹   XP_038939723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,529,988 - 118,604,796 (+)NCBI
mRatBN7.29111,083,378 - 111,158,193 (+)NCBI
RefSeq Acc Id: NP_001101706   ⟸   NM_001108236
- UniProtKB: D3ZYB4 (UniProtKB/TrEMBL),   A6KF98 (UniProtKB/TrEMBL),   A0A8I5ZKH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245727   ⟸   XM_006245665
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AH46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245725   ⟸   XM_006245663
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZKH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245724   ⟸   XM_006245662
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JY62 (UniProtKB/TrEMBL),   A0A8I5ZKH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245726   ⟸   XM_006245664
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZKH7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070532   ⟸   ENSRNOT00000082005
Ensembl Acc Id: ENSRNOP00000020476   ⟸   ENSRNOT00000020476
RefSeq Acc Id: XP_038939723   ⟸   XM_039083795
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000078237   ⟸   ENSRNOT00000095983
Ensembl Acc Id: ENSRNOP00000092729   ⟸   ENSRNOT00000113074
Protein Domains
LNS2/PITP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JY62-F1-model_v2 AlphaFold A0A0G2JY62 1-932 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696913
Promoter ID:EPDNEW_R7437
Type:multiple initiation site
Name:Lpin2_1
Description:lipin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.09119,542,383 - 119,542,443EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304588 AgrOrtholog
BioCyc Gene G2FUF-26333 BioCyc
BioCyc Pathway PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
  PWY-8053 [anandamide biosynthesis II] BioCyc
  TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-7782 BioCyc
  PWY-8052 BioCyc
  PWY-8053 BioCyc
  TRIGLSYN-PWY BioCyc
Ensembl Genes ENSRNOG00000014876 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020476 ENTREZGENE
  ENSRNOT00000020476.9 UniProtKB/TrEMBL
  ENSRNOT00000082005 ENTREZGENE
  ENSRNOT00000082005.3 UniProtKB/TrEMBL
  ENSRNOT00000095983 ENTREZGENE
  ENSRNOT00000095983.2 UniProtKB/TrEMBL
  ENSRNOT00000113074.2 UniProtKB/TrEMBL
InterPro HAD-like_sf UniProtKB/TrEMBL
  LIPIN UniProtKB/TrEMBL
  Lipin_mid UniProtKB/TrEMBL
  Lipin_N UniProtKB/TrEMBL
  LNS2 UniProtKB/TrEMBL
  LNS2/PITP UniProtKB/TrEMBL
KEGG Report rno:316737 UniProtKB/TrEMBL
NCBI Gene 316737 ENTREZGENE
PANTHER PHOSPHATIDATE PHOSPHATASE LPIN2 UniProtKB/TrEMBL
  PTHR12181 UniProtKB/TrEMBL
Pfam Lipin_mid UniProtKB/TrEMBL
  Lipin_N UniProtKB/TrEMBL
  LNS2 UniProtKB/TrEMBL
PhenoGen Lpin2 PhenoGen
RatGTEx ENSRNOG00000014876 RatGTEx
SMART LNS2 UniProtKB/TrEMBL
Superfamily-SCOP HAD-like_dom UniProtKB/TrEMBL
UniProt A0A0G2JY62 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AH46 ENTREZGENE, UniProtKB/TrEMBL
  A6KF98 ENTREZGENE, UniProtKB/TrEMBL
  D3ZYB4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Lpin2  lipin 2   Lpin2_predicted  lipin 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lpin2_predicted  lipin 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED