C5h1orf174 (similar to human chromosome 1 open reading frame 174) - Rat Genome Database

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Pathways
Gene: C5h1orf174 (similar to human chromosome 1 open reading frame 174) Rattus norvegicus
Analyze
Symbol: C5h1orf174
Name: similar to human chromosome 1 open reading frame 174
RGD ID: 1304567
Description: Predicted to be located in nucleus. Orthologous to human C1orf174 (chromosome 1 open reading frame 174); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC362671; LOC362671; MGC105699; RGD1304567; similar to RIKEN cDNA A430005L14; UPF0688 protein C1orf174 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85169,798,004 - 169,802,449 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5169,797,951 - 169,802,448 (+)EnsemblGRCr8
mRatBN7.25164,515,578 - 164,520,022 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,515,559 - 164,520,021 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5167,219,688 - 167,224,133 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05169,041,096 - 169,045,541 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,003,545 - 169,007,990 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05171,242,899 - 171,247,344 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,242,897 - 171,247,346 (+)Ensemblrn6Rnor6.0
Rnor_5.05174,734,521 - 174,738,966 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45170,743,188 - 170,747,633 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5162,727,542 - 162,731,987 (+)NCBICelera
RGSC_v3.15170,753,682 - 170,758,126 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
C5h1orf174
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85169,798,004 - 169,802,449 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5169,797,951 - 169,802,448 (+)EnsemblGRCr8
mRatBN7.25164,515,578 - 164,520,022 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,515,559 - 164,520,021 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5167,219,688 - 167,224,133 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05169,041,096 - 169,045,541 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,003,545 - 169,007,990 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05171,242,899 - 171,247,344 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,242,897 - 171,247,346 (+)Ensemblrn6Rnor6.0
Rnor_5.05174,734,521 - 174,738,966 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45170,743,188 - 170,747,633 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5162,727,542 - 162,731,987 (+)NCBICelera
RGSC_v3.15170,753,682 - 170,758,126 (+)NCBI
Cytogenetic Map5q36NCBI
C1orf174
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813,889,133 - 3,900,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13,889,125 - 3,900,293 (-)Ensemblhg38GRCh38
GRCh3713,805,697 - 3,816,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613,795,557 - 3,806,709 (-)NCBIBuild 36Build 36hg18NCBI36
Celera13,059,840 - 3,070,495 (-)NCBICelera
Cytogenetic Map1p36.32NCBI
HuRef13,101,393 - 3,112,467 (-)NCBIHuRef
CHM1_113,792,710 - 3,803,318 (-)NCBICHM1_1
T2T-CHM13v2.013,401,037 - 3,412,176 (-)NCBIT2T-CHM13v2.0
A430005L14Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394154,041,694 - 154,046,382 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4154,041,694 - 154,046,382 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384153,957,237 - 153,961,925 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4153,957,237 - 153,961,925 (+)Ensemblmm10GRCm38
MGSCv374153,331,346 - 153,336,034 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364152,801,037 - 152,805,714 (+)NCBIMGSCv36mm8
Celera4156,245,393 - 156,250,081 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.78NCBI
CUNH1orf174
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554867,831,913 - 7,833,898 (+)Ensembl
ChiLan1.0NW_0049554867,821,396 - 7,834,357 (+)NCBIChiLan1.0ChiLan1.0
C1H1orf174
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21224,399,853 - 224,417,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11223,041,337 - 223,060,587 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012,563,184 - 2,574,235 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113,682,175 - 3,692,621 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13,682,181 - 3,692,637 (-)EnsemblpanPan2panpan1.1
C5H1orf174
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1558,358,540 - 58,366,356 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl558,359,025 - 58,366,243 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha558,368,835 - 58,376,726 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0558,566,043 - 58,573,933 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl558,566,043 - 58,573,907 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1558,573,741 - 58,581,631 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0558,442,648 - 58,450,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0558,832,916 - 58,840,806 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH1orf174
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505829,372,566 - 29,393,056 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493673772,930 - 78,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C6H1orf174
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl665,323,756 - 65,333,886 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1665,326,980 - 65,333,891 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2660,030,404 - 60,037,317 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C20H1orf174
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120127,780,801 - 127,792,440 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20127,780,903 - 127,791,615 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605431,977,059 - 31,988,521 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH1orf174
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248186,691,432 - 6,698,596 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248186,691,416 - 6,698,288 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
C1H1orf174
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v116,757,911 - 6,762,527 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:255
Count of miRNA genes:168
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000032859
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5160111176171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000032859   ⟹   ENSRNOP00000038852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5169,797,951 - 169,802,442 (+)Ensembl
mRatBN7.2 Ensembl5164,515,559 - 164,520,019 (+)Ensembl
Rnor_6.0 Ensembl5171,242,897 - 171,247,346 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112064   ⟹   ENSRNOP00000085164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5169,798,044 - 169,802,448 (+)Ensembl
mRatBN7.2 Ensembl5164,515,618 - 164,520,021 (+)Ensembl
RefSeq Acc Id: NM_001009711   ⟹   NP_001009711
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85169,798,004 - 169,802,449 (+)NCBI
mRatBN7.25164,515,578 - 164,520,022 (+)NCBI
Rnor_6.05171,242,899 - 171,247,344 (+)NCBI
Rnor_5.05174,734,521 - 174,738,966 (+)NCBI
RGSC_v3.45170,743,188 - 170,747,633 (+)RGD
Celera5162,727,542 - 162,731,987 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009711 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87640 (Get FASTA)   NCBI Sequence Viewer  
  EDL81248 (Get FASTA)   NCBI Sequence Viewer  
  EDL81249 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000038852
GenBank Protein Q5M951 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009711   ⟸   NM_001009711
- UniProtKB: Q5M951 (UniProtKB/Swiss-Prot),   A6IUJ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000038852   ⟸   ENSRNOT00000032859
Ensembl Acc Id: ENSRNOP00000085164   ⟸   ENSRNOT00000112064

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M951-F1-model_v2 AlphaFold Q5M951 1-222 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694306
Promoter ID:EPDNEW_R4831
Type:initiation region
Name:RGD1304567_1
Description:similar to RIKEN cDNA A430005L14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05171,242,889 - 171,242,949EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304567 AgrOrtholog
BioCyc Gene G2FUF-38976 BioCyc
Ensembl Genes ENSRNOG00000025034 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000032859 ENTREZGENE
IMAGE_CLONE IMAGE:7308844 IMAGE-MGC_LOAD
InterPro UPF0688 UniProtKB/Swiss-Prot
KEGG Report rno:362671 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105699 IMAGE-MGC_LOAD
NCBI Gene 362671 ENTREZGENE
PANTHER PTHR28491 UniProtKB/Swiss-Prot
  UPF0688 PROTEIN C1ORF174 UniProtKB/Swiss-Prot
Pfam UPF0688 UniProtKB/Swiss-Prot
PhenoGen C5h1orf174 PhenoGen
RatGTEx ENSRNOG00000025034 RatGTEx
UniProt A0A8I6A2P3_RAT UniProtKB/TrEMBL
  A6IUJ7 ENTREZGENE, UniProtKB/TrEMBL
  CA174_RAT UniProtKB/Swiss-Prot
  G3V981_RAT UniProtKB/TrEMBL
  Q5M951 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-29 C5h1orf174  similar to human chromosome 1 open reading frame 174  RGD1304567  similar to RIKEN cDNA A430005L14  Name and Symbol changed 629549 APPROVED
2006-03-30 RGD1304567  similar to RIKEN cDNA A430005L14    LOC362671  Name updated 1299863 APPROVED
2005-12-06 RGD1304567  LOC362671  RGD1304567_predicted  LOC362671 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1304567_predicted  LOC362671 (predicted)  LOC362671_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362671_predicted  LOC362671 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL