St3gal4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4) - Rat Genome Database

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Pathways
Gene: St3gal4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4) Rattus norvegicus
Analyze
Symbol: St3gal4 (Ensembl: Dcps)
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 4 (Ensembl:decapping enzyme, scavenger)
RGD ID: 1303068
Description: Enables beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase. Predicted to be involved in several processes, including positive regulation of leukocyte tethering or rolling; protein glycosylation; and sialylation. Predicted to be located in Golgi cisterna membrane. Orthologous to human ST3GAL4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4); PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha 2,3-sialyltransferase IV; alpha 2,3-ST 4; alpha-2,3-sialyltransferase ST3Gal IV; beta-galactoside alpha-2,3-sialyltransferase 4; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; gal-beta-1,4-GlcNAc-alpha-2,3-sialyltransferase; N-acetyllactosaminide alpha-2,3-sialyltransferase; sialyltransferase 4C; SIAT4-C; siat4c; ST3Gal IV; ST3GalIV
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8841,673,510 - 41,723,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl841,673,510 - 41,712,551 (-)EnsemblGRCr8
mRatBN7.2833,415,666 - 33,465,319 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl833,415,671 - 33,524,389 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx837,488,098 - 37,537,401 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0835,771,138 - 35,820,439 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0833,633,977 - 33,683,280 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0836,264,741 - 36,314,811 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,264,750 - 36,314,811 (-)Ensemblrn6Rnor6.0
Rnor_5.0836,283,778 - 36,333,600 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4834,845,949 - 34,894,795 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera834,834,950 - 34,883,679 (-)NCBICelera
RGSC_v3.1834,854,718 - 34,903,561 (-)NCBI
Cytogenetic Map8q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
benzoates  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
copper(II) chloride  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
doxorubicin  (ISO)
fenofibrate  (ISO)
fipronil  (EXP)
flutamide  (EXP)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (EXP)
indometacin  (ISO)
lead(0)  (ISO)
lithocholic acid  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel sulfate  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
pirinixic acid  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
soyasaponin I  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Three genes that encode human beta-galactoside alpha 2,3-sialyltransferases. Structural analysis and chromosomal mapping studies. Chang ML, etal., Glycobiology 1995 May;5(3):319-25.
2. Association of a 14-3-3 protein with CMP-NeuAc:GM1 alpha 2,3-sialyltransferase. Gao L, etal., Biochem Biophys Res Commun 1996 Jul 5;224(1):103-7.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Purification and characterization of CMP-NeuAc:GM1 (Gal beta 1-4GalNAc) alpha 2-3 sialyltransferase from rat brain. Gu TJ, etal., FEBS Lett. 1990 Nov 26;275(1-2):83-6.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8288606   PMID:9184827   PMID:12477932   PMID:15489334   PMID:15843597   PMID:19946888   PMID:23227193   PMID:23376485  


Genomics

Comparative Map Data
St3gal4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8841,673,510 - 41,723,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl841,673,510 - 41,712,551 (-)EnsemblGRCr8
mRatBN7.2833,415,666 - 33,465,319 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl833,415,671 - 33,524,389 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx837,488,098 - 37,537,401 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0835,771,138 - 35,820,439 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0833,633,977 - 33,683,280 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0836,264,741 - 36,314,811 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,264,750 - 36,314,811 (-)Ensemblrn6Rnor6.0
Rnor_5.0836,283,778 - 36,333,600 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4834,845,949 - 34,894,795 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera834,834,950 - 34,883,679 (-)NCBICelera
RGSC_v3.1834,854,718 - 34,903,561 (-)NCBI
Cytogenetic Map8q21NCBI
ST3GAL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811126,355,686 - 126,414,638 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11126,354,677 - 126,440,344 (+)Ensemblhg38GRCh38
GRCh3711126,225,581 - 126,284,533 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611125,731,306 - 125,789,743 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3411125,731,305 - 125,789,741NCBI
Celera11123,391,253 - 123,450,644 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11122,170,390 - 122,229,420 (+)NCBIHuRef
CHM1_111126,111,806 - 126,170,805 (+)NCBICHM1_1
T2T-CHM13v2.011126,387,091 - 126,446,076 (+)NCBIT2T-CHM13v2.0
St3gal4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39934,957,872 - 35,028,160 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl934,957,872 - 35,030,564 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38935,046,576 - 35,116,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl935,046,576 - 35,119,268 (-)Ensemblmm10GRCm38
MGSCv37934,854,164 - 34,924,395 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36934,796,250 - 34,866,481 (-)NCBIMGSCv36mm8
Celera932,304,334 - 32,354,128 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map919.36NCBI
St3gal4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541227,387,039 - 27,418,770 (+)Ensembl
ChiLan1.0NW_00495541227,376,270 - 27,418,770 (+)NCBIChiLan1.0ChiLan1.0
ST3GAL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29127,037,970 - 127,097,033 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111128,147,838 - 128,204,734 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011121,169,213 - 121,228,287 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111125,079,260 - 125,137,752 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11125,079,260 - 125,141,737 (+)EnsemblpanPan2panpan1.1
ST3GAL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,132,663 - 8,160,008 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,133,085 - 8,141,254 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha58,193,897 - 8,226,014 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.058,088,240 - 8,120,340 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,088,662 - 8,099,036 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,157,943 - 8,189,985 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,131,956 - 8,163,714 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,165,827 - 8,197,913 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
St3gal4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947108,598,516 - 108,643,465 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365725,806,894 - 5,841,550 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365725,806,897 - 5,851,557 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST3GAL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl953,445,591 - 53,486,010 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1953,442,795 - 53,491,847 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2959,294,217 - 59,323,671 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ST3GAL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11117,479,328 - 117,543,262 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1117,480,451 - 117,542,671 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660438,530,719 - 8,590,666 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St3gal4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624812509,841 - 553,894 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624812503,703 - 551,907 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
St3gal4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1830,612,338 - 30,661,069 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in St3gal4
513 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:207
Count of miRNA genes:140
Interacting mature miRNAs:167
Transcripts:ENSRNOT00000013243
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625851589833Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)83776085958991895Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)83776085961459705Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625867378345Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)83412590255607752Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
70206Alc20Alcohol consumption QTL 202drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)83910625849610361Rat

Markers in Region
D8Rat82  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8841,708,606 - 41,708,837 (+)Marker Load Pipeline
mRatBN7.2833,450,762 - 33,450,993 (+)MAPPERmRatBN7.2
Rnor_6.0836,300,978 - 36,301,208NCBIRnor6.0
Rnor_5.0836,319,764 - 36,319,994UniSTSRnor5.0
RGSC_v3.4834,881,068 - 34,881,303RGDRGSC3.4
RGSC_v3.4834,881,069 - 34,881,303UniSTSRGSC3.4
Celera834,869,958 - 34,870,188UniSTS
RGSC_v3.1834,889,835 - 34,890,069RGD
RH 3.4 Map8290.6UniSTS
RH 3.4 Map8290.6RGD
RH 2.0 Map8211.8RGD
FHH x ACI Map826.99RGD
Cytogenetic Map8q21UniSTS
RH131728  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2833,415,808 - 33,415,999 (+)MAPPERmRatBN7.2
Rnor_6.0836,264,884 - 36,265,074NCBIRnor6.0
Rnor_5.0836,283,921 - 36,284,111UniSTSRnor5.0
RGSC_v3.4834,846,087 - 34,846,277UniSTSRGSC3.4
Celera834,835,088 - 34,835,278UniSTS
RH 3.4 Map8288.6UniSTS
Cytogenetic Map8q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001393863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001393864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001393865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001393866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_203337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ626825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000013243   ⟹   ENSRNOP00000013243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,415,680 - 33,464,459 (-)Ensembl
Rnor_6.0 Ensembl836,264,750 - 36,314,811 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000013763   ⟹   ENSRNOP00000013763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,471,691 - 33,524,389 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093795   ⟹   ENSRNOP00000077981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,415,912 - 33,464,433 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097121   ⟹   ENSRNOP00000097139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,415,671 - 33,524,389 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099496   ⟹   ENSRNOP00000089685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,415,736 - 33,464,236 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102578   ⟹   ENSRNOP00000094974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,472,487 - 33,524,389 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108283   ⟹   ENSRNOP00000082289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,415,851 - 33,524,389 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116357   ⟹   ENSRNOP00000079877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,415,701 - 33,446,918 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116767   ⟹   ENSRNOP00000081971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl833,415,675 - 33,454,707 (-)Ensembl
RefSeq Acc Id: NM_001393863   ⟹   NP_001380792
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,722,347 (-)NCBI
mRatBN7.2833,415,666 - 33,464,508 (-)NCBI
RefSeq Acc Id: NM_001393864   ⟹   NP_001380793
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,704,810 (-)NCBI
mRatBN7.2833,415,666 - 33,446,966 (-)NCBI
RefSeq Acc Id: NM_001393865   ⟹   NP_001380794
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,723,158 (-)NCBI
mRatBN7.2833,415,666 - 33,465,319 (-)NCBI
RefSeq Acc Id: NM_001393866   ⟹   NP_001380795
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,722,347 (-)NCBI
mRatBN7.2833,415,666 - 33,464,508 (-)NCBI
RefSeq Acc Id: NM_203337   ⟹   NP_976082
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,722,347 (-)NCBI
mRatBN7.2833,415,666 - 33,464,508 (-)NCBI
Rnor_6.0836,264,746 - 36,314,811 (-)NCBI
Rnor_5.0836,283,778 - 36,333,600 (-)NCBI
RGSC_v3.4834,845,949 - 34,894,795 (-)RGD
Celera834,834,950 - 34,883,679 (-)RGD
Sequence:
RefSeq Acc Id: XM_008766060   ⟹   XP_008764282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,704,501 (-)NCBI
mRatBN7.2833,415,666 - 33,446,655 (-)NCBI
Rnor_6.0836,264,741 - 36,298,391 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039081719   ⟹   XP_038937647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,705,597 (-)NCBI
mRatBN7.2833,415,666 - 33,447,767 (-)NCBI
RefSeq Acc Id: XM_063265735   ⟹   XP_063121805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,705,600 (-)NCBI
RefSeq Acc Id: XM_063265736   ⟹   XP_063121806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,722,380 (-)NCBI
RefSeq Acc Id: XM_063265738   ⟹   XP_063121808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,722,781 (-)NCBI
RefSeq Acc Id: XM_063265739   ⟹   XP_063121809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,673,510 - 41,722,781 (-)NCBI
RefSeq Acc Id: NP_976082   ⟸   NM_203337
- Peptide Label: isoform 1
- UniProtKB: P61131 (UniProtKB/Swiss-Prot),   A0A8L2Q6D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764282   ⟸   XM_008766060
- Peptide Label: isoform X4
- UniProtKB: P61131 (UniProtKB/Swiss-Prot),   A0A8L2Q6D7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013243   ⟸   ENSRNOT00000013243
RefSeq Acc Id: XP_038937647   ⟸   XM_039081719
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNH8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077981   ⟸   ENSRNOT00000093795
Ensembl Acc Id: ENSRNOP00000082289   ⟸   ENSRNOT00000108283
Ensembl Acc Id: ENSRNOP00000094974   ⟸   ENSRNOT00000102578
Ensembl Acc Id: ENSRNOP00000013763   ⟸   ENSRNOT00000013763
Ensembl Acc Id: ENSRNOP00000097139   ⟸   ENSRNOT00000097121
Ensembl Acc Id: ENSRNOP00000081971   ⟸   ENSRNOT00000116767
Ensembl Acc Id: ENSRNOP00000079877   ⟸   ENSRNOT00000116357
Ensembl Acc Id: ENSRNOP00000089685   ⟸   ENSRNOT00000099496
RefSeq Acc Id: NP_001380794   ⟸   NM_001393865
- Peptide Label: isoform 2
- UniProtKB: A0A8L2Q6D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380795   ⟸   NM_001393866
- Peptide Label: isoform 2
- UniProtKB: A0A8L2Q6D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380792   ⟸   NM_001393863
- Peptide Label: isoform 1
- UniProtKB: P61131 (UniProtKB/Swiss-Prot),   A0A8L2Q6D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380793   ⟸   NM_001393864
- Peptide Label: isoform 1
- UniProtKB: P61131 (UniProtKB/Swiss-Prot),   A0A8L2Q6D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121809   ⟸   XM_063265739
- Peptide Label: isoform X6
- UniProtKB: A0A8L2Q6D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121808   ⟸   XM_063265738
- Peptide Label: isoform X5
- UniProtKB: A0A8L2Q6D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121806   ⟸   XM_063265736
- Peptide Label: isoform X3
- UniProtKB: A0A8L2Q6D7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121805   ⟸   XM_063265735
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZNH8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61131-F1-model_v2 AlphaFold P61131 1-333 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695834
Promoter ID:EPDNEW_R6358
Type:initiation region
Name:St3gal4_1
Description:ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0836,314,754 - 36,314,814EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303068 AgrOrtholog
BioCyc Gene G2FUF-31200 BioCyc
BioCyc Pathway PWY-7831 [ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide] BioCyc
BioCyc Pathway Image PWY-7831 BioCyc
Ensembl Genes ENSRNOG00000009850 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000013243 ENTREZGENE
  ENSRNOT00000093795 ENTREZGENE
  ENSRNOT00000116357 ENTREZGENE
Gene3D-CATH 3.90.1480.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7315905 IMAGE-MGC_LOAD
InterPro Glyco_trans_29 UniProtKB/Swiss-Prot
  Glycosyltransferase_29 UniProtKB/Swiss-Prot
  GT29-like_sf UniProtKB/Swiss-Prot
  Sialyl_trans UniProtKB/Swiss-Prot
KEGG Report rno:363040 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105257 IMAGE-MGC_LOAD
NCBI Gene 363040 ENTREZGENE
PANTHER CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 4 UniProtKB/Swiss-Prot
  SIALYLTRANSFERASE UniProtKB/Swiss-Prot
Pfam Glyco_transf_29 UniProtKB/Swiss-Prot
PhenoGen St3gal4 PhenoGen
PIRSF Sialyl_trans UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009850 RatGTEx
UniProt A0A8I5YCL3_RAT UniProtKB/TrEMBL
  A0A8I5ZNH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AW14_RAT UniProtKB/TrEMBL
  A0A8I6G8R8_RAT UniProtKB/TrEMBL
  A0A8I6GHJ6_RAT UniProtKB/TrEMBL
  A0A8L2Q6D7 ENTREZGENE, UniProtKB/TrEMBL
  A6JYJ3_RAT UniProtKB/TrEMBL
  P61131 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 St3gal4  ST3 beta-galactoside alpha-2,3-sialyltransferase 4  siat4c  alpha-2,3-sialyltransferase ST3Gal IV  Symbol and Name updated 1299863 APPROVED
2005-02-14 siat4c  alpha-2,3-sialyltransferase ST3Gal IV      Symbol and Name status set to provisional 70820 PROVISIONAL