Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gatd3a | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Gatd3a (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of GATD3A mRNA | CTD | PMID:22206623 | Gatd3a | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of GATD3A protein | CTD | PMID:32145629 | Gatd3a | Rat | 17beta-estradiol | decreases expression | ISO | Gatd3a (Mus musculus) | 6480464 | Estradiol results in decreased expression of GATD3A mRNA | CTD | PMID:39298647 | Gatd3a | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Gatd3a (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of GATD3A mRNA | CTD | PMID:31388691 | Gatd3a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GATD3A mRNA | CTD | PMID:21215274 | Gatd3a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GATD3A mRNA | CTD | PMID:33387578 | Gatd3a | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases expression | ISO | GATD3 (Homo sapiens) | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GATD3 mRNA | CTD | PMID:19692669 | Gatd3a | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of GATD3A mRNA | CTD | PMID:31881176 | Gatd3a | Rat | acetylsalicylic acid | increases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Aspirin results in increased expression of GATD3 mRNA | CTD | PMID:11906190 | Gatd3a | Rat | acrolein | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Gatd3a | Rat | acrylamide | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of GATD3 mRNA | CTD | PMID:32763439 | Gatd3a | Rat | aflatoxin B1 | decreases methylation | ISO | GATD3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of GATD3 intron | CTD | PMID:30157460 | Gatd3a | Rat | alpha-pinene | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Gatd3a | Rat | aminoglutethimide | increases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Aminoglutethimide results in increased expression of GATD3 protein | CTD | PMID:26102013 | Gatd3a | Rat | arsane | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of GATD3 more ... | CTD | PMID:39836092 | Gatd3a | Rat | arsenic atom | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of GATD3 more ... | CTD | PMID:39836092 | Gatd3a | Rat | atrazine | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of GATD3 mRNA | CTD | PMID:22378314 | Gatd3a | Rat | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Gatd3a | Rat | benzo[a]pyrene | increases methylation | ISO | GATD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of GATD3 promoter | CTD | PMID:27901495 | Gatd3a | Rat | benzo[a]pyrene | decreases methylation | ISO | GATD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of GATD3 3' UTR | CTD | PMID:27901495 | Gatd3a | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of GATD3A gene | CTD | PMID:28505145 | Gatd3a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GATD3A mRNA | CTD | PMID:34947998 | Gatd3a | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GATD3A protein | CTD | PMID:32145629 | Gatd3a | Rat | cadmium atom | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GATD3 more ... | CTD | PMID:35301059 | Gatd3a | Rat | cadmium atom | multiple interactions | ISO | Gatd3a (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GATD3A more ... | CTD | PMID:37236586 | Gatd3a | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of GATD3A promoter | CTD | PMID:22457795 | Gatd3a | Rat | cadmium dichloride | multiple interactions | ISO | Gatd3a (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GATD3A more ... | CTD | PMID:37236586 | Gatd3a | Rat | cadmium dichloride | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GATD3 more ... | CTD | PMID:35301059 | Gatd3a | Rat | capecitabine | increases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Capecitabine results in increased expression of GATD3A mRNA | CTD | PMID:36183961 | Gatd3a | Rat | celastrol | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | celastrol results in decreased expression of GATD3 mRNA | CTD | PMID:17010675 | Gatd3a | Rat | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Gatd3a | Rat | cobalt dichloride | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of GATD3 mRNA | CTD | PMID:19376846 | Gatd3a | Rat | copper(II) sulfate | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of GATD3 mRNA | CTD | PMID:19549813 | Gatd3a | Rat | cyclosporin A | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of GATD3 mRNA | CTD | PMID:20106945|PMID:25562108 | Gatd3a | Rat | dexamethasone | decreases expression | ISO | Gatd3a (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of GATD3A protein | CTD | PMID:33567340 | Gatd3a | Rat | Dibutyl phosphate | affects expression | ISO | GATD3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of GATD3A mRNA | CTD | PMID:37042841 | Gatd3a | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of GATD3A mRNA | CTD | PMID:21266533 | Gatd3a | Rat | doxorubicin | increases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of GATD3 mRNA | CTD | PMID:29803840 | Gatd3a | Rat | folic acid | multiple interactions | ISO | Gatd3a (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of GATD3A mRNA | CTD | PMID:22206623 | Gatd3a | Rat | gedunin | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | gedunin results in decreased expression of GATD3 mRNA | CTD | PMID:17010675 | Gatd3a | Rat | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Gatd3a | Rat | GSK-J4 | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | GSK-J4 results in decreased expression of GATD3 mRNA | CTD | PMID:29301935 | Gatd3a | Rat | hydralazine | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of GATD3 mRNA | CTD | PMID:17183730 | Gatd3a | Rat | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Gatd3a | Rat | isotretinoin | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of GATD3 mRNA | CTD | PMID:20436886 | Gatd3a | Rat | methyl methanesulfonate | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of GATD3 mRNA | CTD | PMID:23649840 | Gatd3a | Rat | methylmercury chloride | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of GATD3 mRNA | CTD | PMID:28001369 | Gatd3a | Rat | methylseleninic acid | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | methylselenic acid results in decreased expression of GATD3 mRNA | CTD | PMID:18548127 | Gatd3a | Rat | nitrates | multiple interactions | ISO | Gatd3a (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of GATD3A more ... | CTD | PMID:35964746 | Gatd3a | Rat | ozone | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Gatd3a | Rat | paracetamol | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of GATD3 mRNA | CTD | PMID:29067470 | Gatd3a | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of GATD3A mRNA | CTD | PMID:33387578 | Gatd3a | Rat | perfluorooctanoic acid | increases expression | ISO | GATD3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of GATD3 protein | CTD | PMID:26879310 | Gatd3a | Rat | Propiverine | affects binding | EXP | | 6480464 | propiverine binds to GATD3A protein | CTD | PMID:29273565 | Gatd3a | Rat | resveratrol | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of GATD3 mRNA | CTD | PMID:23557933 | Gatd3a | Rat | sodium arsenite | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of GATD3A mRNA | CTD | PMID:38568856 | Gatd3a | Rat | sodium arsenite | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of GATD3 more ... | CTD | PMID:39836092 | Gatd3a | Rat | sulindac | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Sulindac results in decreased expression of GATD3 mRNA | CTD | PMID:11906190 | Gatd3a | Rat | sunitinib | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of GATD3 mRNA | CTD | PMID:31533062 | Gatd3a | Rat | tert-butyl hydroperoxide | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of GATD3 mRNA | CTD | PMID:15336504 | Gatd3a | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of GATD3A mRNA | CTD | PMID:31150632 | Gatd3a | Rat | tetrachloromethane | decreases expression | ISO | Gatd3a (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of GATD3A mRNA | CTD | PMID:31919559 | Gatd3a | Rat | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Gatd3a | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of GATD3A mRNA | CTD | PMID:23411599|PMID:34492290 | Gatd3a | Rat | titanium dioxide | decreases methylation | ISO | Gatd3a (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of GATD3A gene | CTD | PMID:35295148 | Gatd3a | Rat | triphenyl phosphate | affects expression | ISO | GATD3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of GATD3A mRNA | CTD | PMID:37042841 | Gatd3a | Rat | tunicamycin | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of GATD3 mRNA | CTD | PMID:22378314 | Gatd3a | Rat | urethane | decreases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of GATD3 mRNA | CTD | PMID:28818685 | Gatd3a | Rat | valproic acid | multiple interactions | ISO | GATD3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of GATD3 mRNA | CTD | PMID:17183730 | Gatd3a | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of GATD3A mRNA | CTD | PMID:22570695 | Gatd3a | Rat | vitamin E | increases expression | ISO | GATD3 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of GATD3 mRNA | CTD | PMID:19244175 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















