Uqcrbl2 (ubiquinol-cytochrome c reductase binding protein like 2) - Rat Genome Database

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Pathways
Gene: Uqcrbl2 (ubiquinol-cytochrome c reductase binding protein like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Uqcrbl2
Name: ubiquinol-cytochrome c reductase binding protein like 2
RGD ID: 9466192
Description: Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in inherited metabolic disorder and mitochondrial complex III deficiency nuclear type 3. Orthologous to human UQCRB (ubiquinol-cytochrome c reductase binding protein).
Type: protein-coding (Ensembl: processed_pseudogene)
RefSeq Status: MODEL
Previously known as: cytochrome b-c1 complex subunit 7 pseudogene; cytochrome b-c1 complex subunit 7-like; LOC103693740; LOC692017; similar to ubiquinol-cytochrome c reductase binding protein; ubiquinol-cytochrome c reductase binding protein; ubiquinol-cytochrome c reductase binding protein like 1; ubiquinol-cytochrome c reductase binding protein-like; Uqcrbl1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81565,168,285 - 65,168,608 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1565,168,285 - 65,168,608 (+)EnsemblGRCr8
mRatBN7.21558,759,343 - 58,759,666 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1558,759,343 - 58,759,666 (+)EnsemblmRatBN7.2
Rnor_6.01566,165,529 - 66,165,852 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01569,802,435 - 69,802,758 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41564,854,138 - 64,854,461 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1558,301,687 - 58,302,010 (+)NCBICelera
Cytogenetic Map15q12NCBI
JBrowse:




References

Genomics

Variants

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Variants in Uqcrbl2
2 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1560213984105213984Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)156244089297773284Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155720389580107161Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1564571127108192169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)1561710951106710951Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1559257087104257087Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_039093788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_039093788   ⟹   XP_038949716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81565,168,285 - 65,168,608 (+)NCBI
mRatBN7.21558,759,343 - 58,759,666 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038949716 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_038949716   ⟸   XM_039093788
- UniProtKB: A0A8I6A496 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:9466192 AgrOrtholog
BioCyc Gene G2FUF-12959 BioCyc
Ensembl Genes ENSRNOG00000038122 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000058010 ENTREZGENE
NCBI Gene LOC103693740 ENTREZGENE
PhenoGen Uqcrbl2 PhenoGen
RatGTEx ENSRNOG00000038122 RatGTEx
UniProt A0A8I6A496 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-17 Uqcrbl2  ubiquinol-cytochrome c reductase binding protein like 2  Uqcrbl1  ubiquinol-cytochrome c reductase binding protein like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Uqcrbl1  ubiquinol-cytochrome c reductase binding protein like 1  LOC103693740  cytochrome b-c1 complex subunit 7 pseudogene  Symbol and Name Changed 1299863 APPROVED
2015-07-29 LOC103693740  cytochrome b-c1 complex subunit 7 pseudogene  LOC692017  similar to ubiquinol-cytochrome c reductase binding protein  Data merged from RGD:1592155 737654 PROVISIONAL
2014-08-25 LOC103693740  cytochrome b-c1 complex subunit 7 pseudogene      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-05-24 LOC692017  similar to ubiquinol-cytochrome c reductase binding protein  LOC100363906  ubiquinol-cytochrome c reductase binding protein-like  Data merged from RGD:2322050 1643240 APPROVED
2010-05-06 LOC100363906  ubiquinol-cytochrome c reductase binding protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC692017  similar to ubiquinol-cytochrome c reductase binding protein  LOC686420  similar to ubiquinol-cytochrome c reductase binding protein  Data merged from RGD:1597664 1643240 APPROVED
2006-11-20 LOC692017  similar to ubiquinol-cytochrome c reductase binding protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC686420  similar to ubiquinol-cytochrome c reductase binding protein      Symbol and Name status set to provisional 70820 PROVISIONAL