Rpl35al1 (ribosomal protein L35A like 1) - Rat Genome Database

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Gene: Rpl35al1 (ribosomal protein L35A like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rpl35al1 (Ensembl: Rpl35a-ps6)
Name: ribosomal protein L35A like 1 (Ensembl:ribosomal protein L35A, pseudogene 6)
RGD ID: 9247033
Description: Predicted to enable tRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L35a; 60S ribosomal protein L35a-like; large ribosomal subunit protein eL33; LOC100910496; LOC103690996; uncharacterized LOC103690996
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81211,108,520 - 11,109,054 (-)NCBIGRCr8
mRatBN7.2126,072,279 - 6,072,780 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl126,072,271 - 6,074,618 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl5158,537,765 - 158,544,128 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0127,424,216 - 7,424,741 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,923,302 - 164,923,634 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl127,186,473 - 7,186,873 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,395,276 - 219,395,623 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl127,424,258 - 7,424,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,139,292 - 135,139,621 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0129,510,946 - 9,511,390 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera127,830,935 - 7,831,457 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3753935  


Genomics

Variants

.
Variants in Rpl35al1
1 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12390696910373166Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 40 59 43 19 43 6 8 83 37 45 11 6
Low 7 57 52 52 6 52 2 9 87 33 57 7 2
Below cutoff 2 17 13 13 3 13 2 34 21 8 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000042285   ⟹   ENSRNOP00000041209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,537,765 - 158,544,128 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000043508   ⟹   ENSRNOP00000049054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,733,943 - 129,734,345 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117103   ⟹   ENSRNOP00000092003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl126,072,271 - 6,074,618 (-)Ensembl
RefSeq Acc Id: XM_017598483   ⟹   XP_017453972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,108,520 - 11,109,054 (-)NCBI
mRatBN7.2126,072,279 - 6,072,780 (-)NCBI
Rnor_6.0127,424,216 - 7,424,741 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_017453972   ⟸   XM_017598483
- UniProtKB: P04646 (UniProtKB/Swiss-Prot),   A6IRM5 (UniProtKB/TrEMBL),   A0A8L2QJQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000092003   ⟸   ENSRNOT00000117103
RefSeq Acc Id: ENSRNOP00000049054   ⟸   ENSRNOT00000043508
RefSeq Acc Id: ENSRNOP00000041209   ⟸   ENSRNOT00000042285

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P04646-F1-model_v2 AlphaFold P04646 1-110 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698400
Promoter ID:EPDNEW_R8918
Type:multiple initiation site
Name:LOC103690996_1
Description:uncharacterized LOC103690996
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0127,424,722 - 7,424,782EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:9247033 AgrOrtholog
BioCyc Gene G2FUF-20153 BioCyc
Ensembl Genes ENSRNOG00000031641 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000032303 Ensembl
  ENSRNOG00000032348 Ensembl
  ENSRNOG00000047557 Ensembl
  ENSRNOG00000049536 Ensembl
  ENSRNOG00000069961 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000070978 UniProtKB/TrEMBL
  ENSRNOG00055003798 UniProtKB/Swiss-Prot
  ENSRNOG00055023571 UniProtKB/Swiss-Prot
  ENSRNOG00055024608 UniProtKB/Swiss-Prot
  ENSRNOG00055031861 UniProtKB/Swiss-Prot
  ENSRNOG00060001812 UniProtKB/Swiss-Prot
  ENSRNOG00060002322 UniProtKB/Swiss-Prot
  ENSRNOG00060020099 UniProtKB/Swiss-Prot
  ENSRNOG00060028345 UniProtKB/Swiss-Prot
  ENSRNOG00060030685 UniProtKB/Swiss-Prot
  ENSRNOG00060033224 UniProtKB/Swiss-Prot
  ENSRNOG00065006384 UniProtKB/Swiss-Prot
  ENSRNOG00065021170 UniProtKB/Swiss-Prot
  ENSRNOG00065029739 UniProtKB/Swiss-Prot
  ENSRNOG00065033974 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000042285.5 UniProtKB/TrEMBL
  ENSRNOT00000050438.3 UniProtKB/TrEMBL
  ENSRNOT00000117103.1 UniProtKB/Swiss-Prot
  ENSRNOT00055005990 UniProtKB/Swiss-Prot
  ENSRNOT00055040500 UniProtKB/Swiss-Prot
  ENSRNOT00055042335 UniProtKB/Swiss-Prot
  ENSRNOT00055055141 UniProtKB/Swiss-Prot
  ENSRNOT00060002782 UniProtKB/Swiss-Prot
  ENSRNOT00060003655 UniProtKB/Swiss-Prot
  ENSRNOT00060034782 UniProtKB/Swiss-Prot
  ENSRNOT00060049255 UniProtKB/Swiss-Prot
  ENSRNOT00060053309 UniProtKB/Swiss-Prot
  ENSRNOT00060057595 UniProtKB/Swiss-Prot
  ENSRNOT00065009802 UniProtKB/Swiss-Prot
  ENSRNOT00065035985 UniProtKB/Swiss-Prot
  ENSRNOT00065051358 UniProtKB/Swiss-Prot
  ENSRNOT00065058356 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.10.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro L35A_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L35A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L35Ae_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:103690996 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  rno:108349682 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  rno:57809 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene LOC103690996 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L35A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10902 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L35Ae UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rpl35al1 PhenoGen
PROSITE RIBOSOMAL_L35AE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031641 RatGTEx
  ENSRNOG00000032303 RatGTEx
  ENSRNOG00000032348 RatGTEx
  ENSRNOG00000047557 RatGTEx
  ENSRNOG00000049536 RatGTEx
  ENSRNOG00000065971 RatGTEx
  ENSRNOG00000069961 RatGTEx
  ENSRNOG00000070978 RatGTEx
  ENSRNOG00055003798 RatGTEx
  ENSRNOG00055023571 RatGTEx
  ENSRNOG00055024608 RatGTEx
  ENSRNOG00055031861 RatGTEx
  ENSRNOG00060001812 RatGTEx
  ENSRNOG00060002322 RatGTEx
  ENSRNOG00060020099 RatGTEx
  ENSRNOG00060028345 RatGTEx
  ENSRNOG00060030685 RatGTEx
  ENSRNOG00060033224 RatGTEx
  ENSRNOG00065006384 RatGTEx
  ENSRNOG00065021170 RatGTEx
  ENSRNOG00065029739 RatGTEx
  ENSRNOG00065033974 RatGTEx
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QJQ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QK69_RAT UniProtKB/TrEMBL
  A6IRM5 ENTREZGENE, UniProtKB/TrEMBL
  P04646 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rpl35al1  ribosomal protein L35A like 1  LOC103690996  uncharacterized LOC103690996  Symbol and Name Changed 1299863 APPROVED
2015-07-29 LOC103690996  uncharacterized LOC103690996  LOC100910496  60S ribosomal protein L35a-like  Data merged from RGD:6498396 737654 PROVISIONAL
2014-08-25 LOC103690996  uncharacterized LOC103690996      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100910496  60S ribosomal protein L35a-like      Symbol and Name status set to provisional 70820 PROVISIONAL