Eef1a1l2 (eukaryotic translation elongation factor 1 alpha 1 like 2) - Rat Genome Database

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Gene: Eef1a1l2 (eukaryotic translation elongation factor 1 alpha 1 like 2) Rattus norvegicus
Analyze
Symbol: Eef1a1l2 (Ensembl: AABR07054368.1)
Name: eukaryotic translation elongation factor 1 alpha 1 like 2
RGD ID: 9202998
Description: Predicted to enable GTP binding activity; GTPase activity; and translation elongation factor activity. Predicted to be involved in regulation of postsynaptic specialization assembly and translational elongation. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elongation factor 1-alpha 1 pseudogene; elongation factor 1-alpha 1-like; eukaryotic translation elongation factor 1 alpha 2; LOC100360150; LOC103691939
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83163,598,531 - 163,601,027 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3163,598,840 - 163,601,002 (-)EnsemblGRCr8
mRatBN7.23143,138,360 - 143,139,773 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3143,138,640 - 143,140,802 (-)EnsemblmRatBN7.2
Rnor_6.03150,154,373 - 150,155,813 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03156,526,192 - 156,527,614 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43145,106,442 - 145,114,354 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Cytogenetic Map3q41NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Eef1a1l2
8 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3160357340167835660Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 52 67 138 95 11 51 36 32 17 17

Sequence


RefSeq Acc Id: XM_039106696   ⟹   XP_038962624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83163,598,531 - 163,601,027 (-)NCBI
mRatBN7.23143,138,360 - 143,139,773 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038962624 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000038718.4
RefSeq Acc Id: XP_038962624   ⟸   XM_039106696
- UniProtKB: F1M6C2 (UniProtKB/TrEMBL)
Protein Domains
tr-type G

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-47164 BioCyc
Ensembl Genes ENSRNOG00000029996 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036217.5 UniProtKB/TrEMBL
Gene3D-CATH P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
InterPro EFTu-like_2 UniProtKB/TrEMBL
  GTP-eEF1A_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  T_Tr_GTP-bd_dom UniProtKB/TrEMBL
  TRAFAC_GTPase_members UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/TrEMBL
  Transl_elong_EF1A/Init_IF2_C UniProtKB/TrEMBL
  Transl_elong_EF1A_euk/arc UniProtKB/TrEMBL
NCBI Gene LOC103691939 ENTREZGENE
PANTHER TRANSLATION FACTOR UniProtKB/TrEMBL
Pfam GTP-eEF1A_C UniProtKB/TrEMBL
  GTP_EFTU UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/TrEMBL
PhenoGen Eef1a1l2 PhenoGen
PRINTS ELONGATNFCT UniProtKB/TrEMBL
PROSITE G_TR_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029996 RatGTEx
Superfamily-SCOP EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain UniProtKB/TrEMBL
  P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
  Translation proteins UniProtKB/TrEMBL
UniProt F1M6C2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Eef1a1l2  eukaryotic translation elongation factor 1 alpha 1 like 2  LOC103691939  elongation factor 1-alpha 1 pseudogene  Symbol and Name Changed 1299863 APPROVED
2015-07-29 LOC103691939  elongation factor 1-alpha 1 pseudogene  LOC100360150  eukaryotic translation elongation factor 1 alpha 2  Data merged from RGD:2322699 737654 PROVISIONAL
2014-08-25 LOC103691939  elongation factor 1-alpha 1 pseudogene      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-06 LOC100360150  eukaryotic translation elongation factor 1 alpha 2      Symbol and Name status set to provisional 70820 PROVISIONAL