Sh3rf1 (SH3 domain containing ring finger 1) - Rat Genome Database

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Gene: Sh3rf1 (SH3 domain containing ring finger 1) Rattus norvegicus
Analyze
Symbol: Sh3rf1
Name: SH3 domain containing ring finger 1
RGD ID: 735154
Description: Predicted to enable MAP-kinase scaffold activity and ubiquitin protein ligase activity. Involved in response to aldosterone. Predicted to be located in lamellipodium. Predicted to be active in cytosol. Biomarker of retinal degeneration. Orthologous to human SH3RF1 (SH3 domain containing ring finger 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase SH3RF1; LOC306417; plenty of SH3s; Posh; putative E3 ubiquitin-protein ligase SH3RF1; putative scaffolding protein POSH; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1; SH3 multiple domains protein 2; Sh3md2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81633,746,396 - 33,912,127 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1633,746,396 - 33,912,153 (-)EnsemblGRCr8
mRatBN7.21628,735,522 - 28,901,261 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1628,735,440 - 28,901,644 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1632,332,610 - 32,494,437 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01635,766,646 - 35,928,162 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01631,968,457 - 32,129,701 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01632,062,425 - 32,227,526 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1632,062,336 - 32,227,491 (-)Ensemblrn6Rnor6.0
Rnor_5.01631,898,366 - 32,062,432 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41632,054,773 - 32,215,987 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1628,732,907 - 28,894,614 (-)NCBICelera
RGSC_v3.11632,054,847 - 32,216,062 (-)NCBI
Cytogenetic Map16p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-nitropyrene  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
ketoconazole  (ISO)
leflunomide  (ISO)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
ochratoxin A  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
permethrin  (EXP)
phenylarsine oxide  (ISO)
poly(I:C)  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
theophylline  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Gene expression changes in the retina after systemic administration of aldosterone. Ono A, etal., Jpn J Ophthalmol. 2018 Jul;62(4):499-507. doi: 10.1007/s10384-018-0595-4. Epub 2018 Apr 30.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways. Tapon N, etal., EMBO J 1998 Mar 2;17(5):1395-404.
8. Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. Wilhelm M, etal., J Biol Chem. 2012 Jan 13;287(3):2247-56. doi: 10.1074/jbc.M111.269431. Epub 2011 Nov 28.
9. Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis. Xu Z, etal., J Biol Chem. 2006 Jan 6;281(1):303-12. Epub 2005 Oct 17.
Additional References at PubMed
PMID:16248889   PMID:17095503   PMID:19710010   PMID:20696164   PMID:21203929   PMID:21586138   PMID:22959435   PMID:23963642   PMID:27084103  


Genomics

Comparative Map Data
Sh3rf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81633,746,396 - 33,912,127 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1633,746,396 - 33,912,153 (-)EnsemblGRCr8
mRatBN7.21628,735,522 - 28,901,261 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1628,735,440 - 28,901,644 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1632,332,610 - 32,494,437 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01635,766,646 - 35,928,162 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01631,968,457 - 32,129,701 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01632,062,425 - 32,227,526 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1632,062,336 - 32,227,491 (-)Ensemblrn6Rnor6.0
Rnor_5.01631,898,366 - 32,062,432 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41632,054,773 - 32,215,987 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1628,732,907 - 28,894,614 (-)NCBICelera
RGSC_v3.11632,054,847 - 32,216,062 (-)NCBI
Cytogenetic Map16p12NCBI
SH3RF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384169,094,259 - 169,270,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4169,094,259 - 169,271,185 (-)Ensemblhg38GRCh38
GRCh374170,015,410 - 170,192,107 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364170,251,982 - 170,428,824 (-)NCBIBuild 36Build 36hg18NCBI36
Build 344170,390,139 - 170,566,895NCBI
Celera4167,346,760 - 167,524,236 (-)NCBICelera
Cytogenetic Map4q32.3-q33NCBI
HuRef4165,769,030 - 165,945,877 (-)NCBIHuRef
CHM1_14169,991,853 - 170,168,646 (-)NCBICHM1_1
T2T-CHM13v2.04172,453,905 - 172,630,687 (-)NCBIT2T-CHM13v2.0
Sh3rf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39861,677,117 - 61,918,327 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl861,676,906 - 61,849,105 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38861,224,083 - 61,465,293 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl861,223,872 - 61,396,071 (+)Ensemblmm10GRCm38
MGSCv37863,702,968 - 63,874,869 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36864,116,351 - 64,288,213 (+)NCBIMGSCv36mm8
Celera863,790,185 - 63,958,432 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map830.94NCBI
Sh3rf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540336,988,811 - 37,142,401 (+)Ensembl
ChiLan1.0NW_00495540336,989,509 - 37,141,188 (+)NCBIChiLan1.0ChiLan1.0
SH3RF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23166,875,833 - 167,052,812 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14167,231,098 - 167,408,041 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04161,319,093 - 161,495,917 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14173,392,485 - 173,569,072 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4173,394,739 - 173,567,096 (-)EnsemblpanPan2panpan1.1
SH3RF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12520,025,920 - 20,208,470 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2520,015,915 - 20,205,946 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2520,662,977 - 20,845,487 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02520,203,292 - 20,385,482 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2520,192,272 - 20,384,617 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12520,047,395 - 20,229,391 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02520,023,046 - 20,205,518 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02520,122,561 - 20,304,972 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sh3rf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494320,852,835 - 21,014,519 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365161,267,029 - 1,428,841 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365161,267,128 - 1,429,040 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3RF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1420,420,618 - 20,559,271 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11420,420,618 - 20,559,273 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21421,797,298 - 21,846,362 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SH3RF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17115,330,171 - 115,504,443 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7115,332,460 - 115,504,411 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603795,262,003 - 95,441,317 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3rf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624769666,406 - 834,156 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624769668,175 - 834,863 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sh3rf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11327,645,779 - 27,803,685 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sh3rf1
747 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:25
Interacting mature miRNAs:27
Transcripts:ENSRNOT00000013816
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162846870173468701Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)163236104377361043Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)163105803976058039Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)163188527176885271Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
RH144421  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21628,883,175 - 28,883,282 (+)MAPPERmRatBN7.2
Rnor_6.01632,209,393 - 32,209,499NCBIRnor6.0
Rnor_5.01632,044,297 - 32,044,403UniSTSRnor5.0
RGSC_v3.41632,199,602 - 32,199,708UniSTSRGSC3.4
Celera1628,878,230 - 28,878,336UniSTS
Cytogenetic Map16p12UniSTS
AU048477  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21628,846,052 - 28,846,255 (+)MAPPERmRatBN7.2
Rnor_6.01632,172,882 - 32,173,084NCBIRnor6.0
Rnor_5.01632,007,026 - 32,007,228UniSTSRnor5.0
RGSC_v3.41632,161,356 - 32,161,558UniSTSRGSC3.4
Celera1628,841,289 - 28,841,491UniSTS
Cytogenetic Map16p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 91 59 6 355 191 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000013816   ⟹   ENSRNOP00000013815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1633,746,396 - 33,912,153 (-)Ensembl
mRatBN7.2 Ensembl1628,735,440 - 28,901,644 (-)Ensembl
Rnor_6.0 Ensembl1632,062,336 - 32,227,491 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158852   ⟹   ENSRNOP00000110766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1633,746,396 - 33,912,127 (-)Ensembl
RefSeq Acc Id: NM_198764   ⟹   NP_942059
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81633,746,396 - 33,912,127 (-)NCBI
mRatBN7.21628,735,522 - 28,901,261 (-)NCBI
Rnor_6.01632,064,626 - 32,225,777 (-)NCBI
Rnor_5.01631,898,366 - 32,062,432 (-)NCBI
RGSC_v3.41632,054,773 - 32,215,987 (-)RGD
Celera1628,732,907 - 28,894,614 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_942059 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAQ08184 (Get FASTA)   NCBI Sequence Viewer  
  EDL87200 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013815
  ENSRNOP00000013815.1
GenBank Protein Q71F54 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_942059   ⟸   NM_198764
- UniProtKB: Q71F54 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013815   ⟸   ENSRNOT00000013816
Ensembl Acc Id: ENSRNOP00000110766   ⟸   ENSRNOT00000158852
Protein Domains
SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q71F54-F1-model_v2 AlphaFold Q71F54 1-894 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700070
Promoter ID:EPDNEW_R10594
Type:multiple initiation site
Name:Sh3rf1_1
Description:SH3 domain containing ring finger 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01632,227,476 - 32,227,536EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735154 AgrOrtholog
BioCyc Gene G2FUF-11583 BioCyc
Ensembl Genes ENSRNOG00000010358 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013816 ENTREZGENE
  ENSRNOT00000013816.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
InterPro Endophilin_SH3RF UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
  SH3RF1/SH3RF3_SH3_4 UniProtKB/Swiss-Prot
  SH3RF1_SH3_2 UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
KEGG Report rno:306417 UniProtKB/Swiss-Prot
NCBI Gene 306417 ENTREZGENE
PANTHER CIN85 AND CD2AP RELATED, ISOFORM J UniProtKB/Swiss-Prot
  SH3 DOMAIN-CONTAINING UniProtKB/Swiss-Prot
Pfam SH3_1 UniProtKB/Swiss-Prot
  SH3_9 UniProtKB/Swiss-Prot
  zf-C3HC4_2 UniProtKB/Swiss-Prot
PhenoGen Sh3rf1 PhenoGen
PRINTS P67PHOX UniProtKB/Swiss-Prot
  SH3DOMAIN UniProtKB/Swiss-Prot
PROSITE SH3 UniProtKB/Swiss-Prot
  ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010358 RatGTEx
SMART RING UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF50044 UniProtKB/Swiss-Prot
UniProt A0ABK0M5I9_RAT UniProtKB/TrEMBL
  Q71F54 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-02 Sh3rf1  SH3 domain containing ring finger 1  Sh3md2  putative scaffolding protein POSH  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Sh3md2  putative scaffolding protein POSH  LOC306417    Symbol and Name updated 1299863 APPROVED