Slc1a4 (solute carrier family 1 member 4) - Rat Genome Database

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Gene: Slc1a4 (solute carrier family 1 member 4) Rattus norvegicus
Analyze
Symbol: Slc1a4
Name: solute carrier family 1 member 4
RGD ID: 735146
Description: Enables L-serine transmembrane transporter activity. Involved in L-serine transport. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in spastic tetraplegia, thin corpus callosum, and progressive microcephaly. Orthologous to human SLC1A4 (solute carrier family 1 member 4); PARTICIPATES IN argininosuccinic aciduria pathway; carbamoyl phosphate synthetase I deficiency pathway; citrullinemia pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ASCT1; neutral amino acid transporter A; neutral amino acid transporter ASCT1; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,718,646 - 98,761,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1498,730,450 - 98,761,790 (-)EnsemblGRCr8
mRatBN7.21494,530,801 - 94,560,190 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,529,084 - 94,560,418 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1498,877,394 - 98,907,056 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,117,664 - 100,147,323 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,585,031 - 96,614,695 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,582,884 - 104,612,417 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,581,190 - 104,612,597 (-)Ensemblrn6Rnor6.0
Rnor_5.014104,317,800 - 104,345,829 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414101,123,740 - 101,153,790 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1493,550,109 - 93,578,743 (-)NCBICelera
RGSC_v3.114101,142,950 - 101,173,001 (-)NCBI
Cytogenetic Map14q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
AM-251  (ISO)
andrographolide  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
chenodeoxycholic acid  (ISO)
chlordecone  (ISO)
chloroacetaldehyde  (ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (EXP,ISO)
DDE  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
drometrizole  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
ethylparaben  (ISO)
fluoranthene  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
genistein  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
GSK-J4  (ISO)
ibuprofen  (ISO)
indole-3-methanol  (EXP)
lamivudine  (ISO)
lead diacetate  (ISO)
lucanthone  (ISO)
mercury dibromide  (ISO)
metformin  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
motexafin gadolinium  (ISO)
N(4)-hydroxycytidine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
prothioconazole  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sinapic acid  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trichloroethene  (EXP)
Triptolide  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zidovudine  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA,ISO)
dendrite  (IDA)
intermediate filament  (IEA,ISO)
melanosome  (IEA)
membrane  (IEA,ISO)
neuronal cell body  (IDA)
plasma membrane  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Ontogeny and localization of the neutral amino acid transporter ASCT1 in rat brain. Weiss MD, etal., Brain Res Dev Brain Res. 2001 Oct 24;130(2):183-90.
7. Characterization of rapid and high-affinity uptake of L-serine in neurons and astrocytes in primary culture. Yamamoto T, etal., FEBS Lett. 2003 Jul 31;548(1-3):69-73.
8. Functional identification of ASCT1 neutral amino acid transporter as the predominant system for the uptake of L-serine in rat neurons in primary culture. Yamamoto T, etal., Neurosci Res 2004 May;49(1):101-11.
Additional References at PubMed
PMID:8101838   PMID:8340364   PMID:8910405   PMID:10933718   PMID:12533615   PMID:14502423   PMID:14622120   PMID:16897601   PMID:19581412   PMID:19946888   PMID:20458337   PMID:25231108  
PMID:26041762   PMID:27272177  


Genomics

Comparative Map Data
Slc1a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,718,646 - 98,761,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1498,730,450 - 98,761,790 (-)EnsemblGRCr8
mRatBN7.21494,530,801 - 94,560,190 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,529,084 - 94,560,418 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1498,877,394 - 98,907,056 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,117,664 - 100,147,323 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,585,031 - 96,614,695 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,582,884 - 104,612,417 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,581,190 - 104,612,597 (-)Ensemblrn6Rnor6.0
Rnor_5.014104,317,800 - 104,345,829 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414101,123,740 - 101,153,790 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1493,550,109 - 93,578,743 (-)NCBICelera
RGSC_v3.114101,142,950 - 101,173,001 (-)NCBI
Cytogenetic Map14q22NCBI
SLC1A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38264,988,479 - 65,023,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl264,988,477 - 65,023,865 (+)Ensemblhg38GRCh38
GRCh37265,215,613 - 65,250,999 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36265,070,098 - 65,104,503 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34265,128,244 - 65,162,648NCBI
Celera265,061,957 - 65,097,385 (+)NCBICelera
Cytogenetic Map2p14NCBI
HuRef264,949,345 - 64,984,802 (+)NCBIHuRef
CHM1_1265,146,566 - 65,181,989 (+)NCBICHM1_1
T2T-CHM13v2.0264,998,100 - 65,033,490 (+)NCBIT2T-CHM13v2.0
Slc1a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,252,180 - 20,282,713 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,252,180 - 20,282,713 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381120,302,180 - 20,332,713 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,302,180 - 20,332,713 (-)Ensemblmm10GRCm38
MGSCv371120,202,183 - 20,232,716 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361120,202,208 - 20,232,674 (-)NCBIMGSCv36mm8
Celera1122,451,521 - 22,482,559 (-)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1112.97NCBI
Slc1a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542419,474,082 - 19,499,592 (-)Ensembl
ChiLan1.0NW_00495542419,474,082 - 19,499,592 (-)NCBIChiLan1.0ChiLan1.0
SLC1A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21261,377,645 - 61,412,341 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A61,380,650 - 61,416,291 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A65,051,025 - 65,086,917 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A66,177,835 - 66,212,249 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A66,176,925 - 66,209,615 (+)EnsemblpanPan2panpan1.1
SLC1A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11064,482,840 - 64,508,288 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1064,483,060 - 64,505,747 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1064,369,739 - 64,394,932 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01065,493,157 - 65,518,318 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1065,492,613 - 65,518,315 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11065,172,083 - 65,197,216 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01065,480,918 - 65,503,851 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01065,774,013 - 65,799,174 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc1a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629218,780,757 - 18,810,279 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364919,760,952 - 9,790,536 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364919,761,002 - 9,790,535 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC1A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl376,938,107 - 76,970,508 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1376,938,102 - 76,970,519 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2380,747,982 - 80,754,397 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC1A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11441,999,216 - 42,032,326 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1441,999,064 - 42,032,288 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604569,848,255 - 69,881,833 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc1a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247628,532,063 - 8,558,994 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247628,532,550 - 8,558,912 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc1a4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11188,587,136 - 88,615,306 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc1a4
199 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:424
Count of miRNA genes:235
Interacting mature miRNAs:276
Transcripts:ENSRNOT00000007002
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)1496755448100078267Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat

Markers in Region
Slc1a4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21494,530,107 - 94,531,106 (+)MAPPERmRatBN7.2
Rnor_6.014104,582,191 - 104,583,189NCBIRnor6.0
Rnor_5.014104,317,107 - 104,318,105UniSTSRnor5.0
Celera1493,549,416 - 93,550,414UniSTS
Cytogenetic Map14q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 160 91 90 59 90 59 6 349 189 9 139 77 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007002   ⟹   ENSRNOP00000007002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1498,730,450 - 98,761,790 (-)Ensembl
mRatBN7.2 Ensembl1494,529,084 - 94,560,418 (-)Ensembl
Rnor_6.0 Ensembl14104,581,190 - 104,612,597 (-)Ensembl
RefSeq Acc Id: NM_198763   ⟹   NP_942058
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,732,167 - 98,761,562 (-)NCBI
mRatBN7.21494,530,801 - 94,560,190 (-)NCBI
Rnor_6.014104,582,884 - 104,612,417 (-)NCBI
Rnor_5.014104,317,800 - 104,345,829 (-)NCBI
RGSC_v3.414101,123,740 - 101,153,790 (-)RGD
Celera1493,550,109 - 93,578,743 (-)RGD
Sequence:
RefSeq Acc Id: XM_063273236   ⟹   XP_063129306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,718,646 - 98,761,672 (-)NCBI
Protein Sequences
Protein RefSeqs NP_942058 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129306 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAC99093 (Get FASTA)   NCBI Sequence Viewer  
  BAR72489 (Get FASTA)   NCBI Sequence Viewer  
  EDL97938 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007002
  ENSRNOP00000007002.2
RefSeq Acc Id: NP_942058   ⟸   NM_198763
- UniProtKB: Q76GL9 (UniProtKB/TrEMBL),   A6JQ21 (UniProtKB/TrEMBL),   A0A0F7R5I4 (UniProtKB/TrEMBL),   F7F9N4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007002   ⟸   ENSRNOT00000007002
RefSeq Acc Id: XP_063129306   ⟸   XM_063273236
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76GL9-F1-model_v2 AlphaFold Q76GL9 1-529 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699510
Promoter ID:EPDNEW_R10034
Type:initiation region
Name:Slc1a4_1
Description:solute carrier family 1 member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014104,612,648 - 104,612,708EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735146 AgrOrtholog
BioCyc Gene G2FUF-14870 BioCyc
Ensembl Genes ENSRNOG00000005248 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007002 ENTREZGENE
  ENSRNOT00000007002.7 UniProtKB/TrEMBL
Gene3D-CATH 1.10.3860.10 UniProtKB/TrEMBL
InterPro DAACS UniProtKB/TrEMBL
  Na-dicarbo_symporter_sf UniProtKB/TrEMBL
  Na-dicarboxylate_symporter UniProtKB/TrEMBL
  Na-dicarboxylate_symporter_CS UniProtKB/TrEMBL
KEGG Report rno:305540 UniProtKB/TrEMBL
NCBI Gene 305540 ENTREZGENE
PANTHER NEUTRAL AMINO ACID TRANSPORTER A UniProtKB/TrEMBL
  SODIUM/DICARBOXYLATE SYMPORTER-RELATED UniProtKB/TrEMBL
Pfam SDF UniProtKB/TrEMBL
PhenoGen Slc1a4 PhenoGen
PRINTS EDTRNSPORT UniProtKB/TrEMBL
PROSITE NA_DICARBOXYL_SYMP_1 UniProtKB/TrEMBL
  NA_DICARBOXYL_SYMP_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005248 RatGTEx
Superfamily-SCOP SSF118215 UniProtKB/TrEMBL
UniProt A0A0F7R5I4 ENTREZGENE, UniProtKB/TrEMBL
  A6JQ21 ENTREZGENE, UniProtKB/TrEMBL
  F7F9N4 ENTREZGENE, UniProtKB/TrEMBL
  Q76GL9 ENTREZGENE
UniProt Secondary Q76GL9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Slc1a4  solute carrier family 1 member 4  Slc1a4  solute carrier family 1 (glutamate/neutral amino acid transporter), member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc1a4  solute carrier family 1 (glutamate/neutral amino acid transporter), member 4      Symbol and Name status set to approved 1299863 APPROVED