Sgsm3 (small G protein signaling modulator 3) - Rat Genome Database

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Pathways
Gene: Sgsm3 (small G protein signaling modulator 3) Rattus norvegicus
Analyze
Symbol: Sgsm3
Name: small G protein signaling modulator 3
RGD ID: 735113
Description: Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in several processes, including Rap protein signal transduction; plasma membrane to endosome transport; and regulation of Rab protein signal transduction. Predicted to be located in cytosol and gap junction. Orthologous to human SGSM3 (small G protein signaling modulator 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bdif-1; hypothetical protein; RUN and TBC1 domain containing 3; RUN and TBC1 domain-containing protein 3; Rutbc3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,394,724 - 114,424,285 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7114,394,813 - 114,424,489 (+)EnsemblGRCr8
mRatBN7.27112,514,453 - 112,544,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,514,630 - 112,544,108 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7114,277,198 - 114,306,669 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,500,742 - 116,530,214 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,470,115 - 116,499,587 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,203,498 - 122,232,993 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,203,532 - 122,232,991 (+)Ensemblrn6Rnor6.0
Rnor_5.07122,187,850 - 122,217,330 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47119,259,355 - 119,306,023 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7108,838,288 - 108,866,794 (+)NCBICelera
RGSC_v3.17119,293,617 - 119,340,248 (+)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA,ISO)
gap junction  (IEA,ISO)
Golgi apparatus  (IEA,ISO)

Molecular Function
GTPase activator activity  (IBA,IEA,ISO,ISS)
protein binding  (ISO)
small GTPase binding  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:15709751   PMID:17509819   PMID:17562788   PMID:17646400   PMID:21453730   PMID:28716730  


Genomics

Comparative Map Data
Sgsm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,394,724 - 114,424,285 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7114,394,813 - 114,424,489 (+)EnsemblGRCr8
mRatBN7.27112,514,453 - 112,544,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,514,630 - 112,544,108 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7114,277,198 - 114,306,669 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,500,742 - 116,530,214 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,470,115 - 116,499,587 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,203,498 - 122,232,993 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,203,532 - 122,232,991 (+)Ensemblrn6Rnor6.0
Rnor_5.07122,187,850 - 122,217,330 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47119,259,355 - 119,306,023 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7108,838,288 - 108,866,794 (+)NCBICelera
RGSC_v3.17119,293,617 - 119,340,248 (+)NCBI
Cytogenetic Map7q34NCBI
SGSM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,370,594 - 40,410,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,370,564 - 40,410,289 (+)Ensemblhg38GRCh38
GRCh372240,766,598 - 40,806,293 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,096,541 - 39,136,239 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342239,091,094 - 39,130,793NCBI
Celera2224,568,657 - 24,608,354 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2223,729,704 - 23,769,396 (+)NCBIHuRef
CHM1_12240,725,487 - 40,765,196 (+)NCBICHM1_1
T2T-CHM13v2.02240,842,001 - 40,880,672 (+)NCBIT2T-CHM13v2.0
Sgsm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,861,966 - 80,896,491 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,861,966 - 80,896,491 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381580,977,762 - 81,012,290 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,977,765 - 81,012,290 (+)Ensemblmm10GRCm38
MGSCv371580,808,195 - 80,842,720 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361580,805,060 - 80,839,326 (+)NCBIMGSCv36mm8
Celera1583,098,059 - 83,132,412 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.96NCBI
Sgsm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,094,146 - 26,142,219 (+)Ensembl
ChiLan1.0NW_00495541326,094,170 - 26,139,062 (+)NCBIChiLan1.0ChiLan1.0
SGSM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22350,216,004 - 50,247,264 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,910,482 - 52,950,196 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02221,275,464 - 21,314,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12239,094,271 - 39,411,884 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2239,402,336 - 39,411,884 (+)EnsemblpanPan2panpan1.1
SGSM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,759,714 - 24,803,333 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1024,760,162 - 24,769,478 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1024,694,730 - 24,738,134 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01025,510,076 - 25,553,515 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1025,509,954 - 25,553,470 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11025,222,399 - 25,265,776 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01025,544,643 - 25,588,214 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01025,718,961 - 25,762,365 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sgsm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049458,371,633 - 8,405,658 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364921,385,347 - 1,416,124 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364921,380,322 - 1,416,060 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGSM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,968,097 - 8,017,768 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.157,976,015 - 8,017,782 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.255,208,551 - 5,250,235 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SGSM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,943,787 - 22,979,899 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,970,595 - 22,982,856 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045102,610,702 - 102,646,800 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgsm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247528,050,342 - 8,093,105 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247528,050,345 - 8,093,119 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sgsm3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11250,733,414 - 250,765,850 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sgsm3
132 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:87
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000025382
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
D7Got104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,522,128 - 112,522,356 (+)MAPPERmRatBN7.2
Rnor_6.07122,211,015 - 122,211,240NCBIRnor6.0
Rnor_5.07122,195,352 - 122,195,577UniSTSRnor5.0
RGSC_v3.47119,284,044 - 119,284,270RGDRGSC3.4
RGSC_v3.47119,284,045 - 119,284,270UniSTSRGSC3.4
Celera7108,845,432 - 108,845,657UniSTS
RGSC_v3.17119,318,275 - 119,318,500RGD
RH 3.4 Map7876.8RGD
RH 3.4 Map7876.8UniSTS
Cytogenetic Map7q34UniSTS
AI428557  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,543,635 - 112,543,805 (+)MAPPERmRatBN7.2
Rnor_6.07122,232,520 - 122,232,689NCBIRnor6.0
Rnor_5.07122,216,857 - 122,217,026UniSTSRnor5.0
RGSC_v3.47119,305,550 - 119,305,719UniSTSRGSC3.4
Celera7108,866,321 - 108,866,490UniSTS
Cytogenetic Map7q34UniSTS
AW821984  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,544,379 - 112,544,531 (+)MAPPERmRatBN7.2
Rnor_6.07122,233,264 - 122,233,415NCBIRnor6.0
Rnor_5.07122,217,601 - 122,217,752UniSTSRnor5.0
RGSC_v3.47119,306,294 - 119,306,445UniSTSRGSC3.4
Celera7108,867,065 - 108,867,216UniSTS
Cytogenetic Map7q34UniSTS
RH131243  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,543,882 - 112,544,063 (+)MAPPERmRatBN7.2
Rnor_6.07122,232,767 - 122,232,947NCBIRnor6.0
Rnor_5.07122,217,104 - 122,217,284UniSTSRnor5.0
RGSC_v3.47119,305,797 - 119,305,977UniSTSRGSC3.4
Celera7108,866,568 - 108,866,748UniSTS
RH 3.4 Map7876.7UniSTS
Cytogenetic Map7q34UniSTS
Sgsm3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,540,425 - 112,541,293 (+)MAPPERmRatBN7.2
Rnor_6.07122,229,310 - 122,230,177NCBIRnor6.0
Rnor_5.07122,213,647 - 122,214,514UniSTSRnor5.0
RGSC_v3.47119,302,340 - 119,303,207UniSTSRGSC3.4
Celera7108,863,111 - 108,863,978UniSTS
Cytogenetic Map7q34UniSTS
Sgsm3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27112,540,425 - 112,541,480 (+)MAPPERmRatBN7.2
Rnor_6.07122,229,310 - 122,230,364NCBIRnor6.0
Rnor_5.07122,213,647 - 122,214,701UniSTSRnor5.0
RGSC_v3.47119,302,340 - 119,303,394UniSTSRGSC3.4
Celera7108,863,111 - 108,864,165UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 91 59 6 355 191 11 140 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_198787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB091009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM385615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB581701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000025382   ⟹   ENSRNOP00000025381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7114,394,813 - 114,424,489 (+)Ensembl
mRatBN7.2 Ensembl7112,514,643 - 112,544,107 (+)Ensembl
Rnor_6.0 Ensembl7122,203,532 - 122,232,991 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098829   ⟹   ENSRNOP00000079207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7114,394,889 - 114,416,648 (+)Ensembl
mRatBN7.2 Ensembl7112,514,634 - 112,536,313 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101805   ⟹   ENSRNOP00000080335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7114,394,889 - 114,424,377 (+)Ensembl
mRatBN7.2 Ensembl7112,514,630 - 112,544,108 (+)Ensembl
RefSeq Acc Id: NM_198787   ⟹   NP_942082
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,822 - 114,424,285 (+)NCBI
mRatBN7.27112,514,643 - 112,544,109 (+)NCBI
Rnor_6.07122,203,532 - 122,232,993 (+)NCBI
Rnor_5.07122,187,850 - 122,217,330 (+)NCBI
RGSC_v3.47119,259,355 - 119,306,023 (+)RGD
Celera7108,838,288 - 108,866,794 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242096   ⟹   XP_006242158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,798 - 114,424,281 (+)NCBI
mRatBN7.27112,514,453 - 112,544,109 (+)NCBI
Rnor_6.07122,203,498 - 122,232,993 (+)NCBI
Rnor_5.07122,187,850 - 122,217,330 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006242099   ⟹   XP_006242161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,724 - 114,424,281 (+)NCBI
mRatBN7.27112,514,454 - 112,543,555 (+)NCBI
Rnor_6.07122,203,498 - 122,232,993 (+)NCBI
Rnor_5.07122,187,850 - 122,217,330 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594989   ⟹   XP_017450478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,403,374 - 114,424,281 (+)NCBI
mRatBN7.27112,532,543 - 112,544,109 (+)NCBI
Rnor_6.07122,219,771 - 122,232,993 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079595   ⟹   XP_038935523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,878 - 114,424,281 (+)NCBI
mRatBN7.27112,514,909 - 112,544,109 (+)NCBI
RefSeq Acc Id: XM_063263926   ⟹   XP_063119996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,403,377 - 114,424,281 (+)NCBI
RefSeq Acc Id: XM_063263927   ⟹   XP_063119997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,395,069 - 114,424,281 (+)NCBI
RefSeq Acc Id: XM_063263928   ⟹   XP_063119998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,870 - 114,424,281 (+)NCBI
RefSeq Acc Id: XM_063263929   ⟹   XP_063119999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87114,394,798 - 114,424,281 (+)NCBI
RefSeq Acc Id: NP_942082   ⟸   NM_198787
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242158   ⟸   XM_006242096
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242161   ⟸   XM_006242099
- Peptide Label: isoform X2
- UniProtKB: A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450478   ⟸   XM_017594989
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025381   ⟸   ENSRNOT00000025382
RefSeq Acc Id: XP_038935523   ⟸   XM_039079595
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079207   ⟸   ENSRNOT00000098829
Ensembl Acc Id: ENSRNOP00000080335   ⟸   ENSRNOT00000101805
RefSeq Acc Id: XP_063119999   ⟸   XM_063263929
- Peptide Label: isoform X2
- UniProtKB: A6HSY2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119998   ⟸   XM_063263928
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119997   ⟸   XM_063263927
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119996   ⟸   XM_063263926
- Peptide Label: isoform X1
- UniProtKB: F1LQU9 (UniProtKB/TrEMBL),   A6HSY2 (UniProtKB/TrEMBL)
Protein Domains
Rab-GAP TBC   RUN   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P6R7-F1-model_v2 AlphaFold Q6P6R7 1-749 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695503
Promoter ID:EPDNEW_R6028
Type:initiation region
Name:Sgsm3_1
Description:small G protein signaling modulator 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07122,203,523 - 122,203,583EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735113 AgrOrtholog
BioCyc Gene G2FUF-32688 BioCyc
Ensembl Genes ENSRNOG00000018745 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000025382 ENTREZGENE
  ENSRNOT00000101805 ENTREZGENE
Gene3D-CATH 1.20.58.900 UniProtKB/Swiss-Prot
  putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5599107 IMAGE-MGC_LOAD
InterPro Rab-GTPase-TBC_dom UniProtKB/Swiss-Prot
  Rab-GTPase_TBC_sf UniProtKB/Swiss-Prot
  Rab_GAP_TBC_domain UniProtKB/Swiss-Prot
  Run_dom UniProtKB/Swiss-Prot
  Run_dom_sf UniProtKB/Swiss-Prot
  SGSM3_SH3 UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
KEGG Report rno:362963 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72600 IMAGE-MGC_LOAD
NCBI Gene 362963 ENTREZGENE
PANTHER RAB GTPASE-ACTIVATING PROTEIN 1-LIKE UniProtKB/Swiss-Prot
  RUN AND TBC1 DOMAIN-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot
Pfam RabGAP-TBC UniProtKB/Swiss-Prot
  RUN UniProtKB/Swiss-Prot
  SH3_1 UniProtKB/Swiss-Prot
PhenoGen Sgsm3 PhenoGen
PROSITE RUN UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
  TBC_RABGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018745 RatGTEx
SMART RUN UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
  TBC UniProtKB/Swiss-Prot
Superfamily-SCOP SSF140741 UniProtKB/Swiss-Prot
  SSF47923 UniProtKB/Swiss-Prot
  SSF50044 UniProtKB/Swiss-Prot
UniProt A0A8I5ZM92_RAT UniProtKB/TrEMBL
  A0A8I5ZPG8_RAT UniProtKB/TrEMBL
  A6HSY2 ENTREZGENE, UniProtKB/TrEMBL
  F1LQU9 ENTREZGENE, UniProtKB/TrEMBL
  Q6P6R7 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q76KK4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Sgsm3  small G protein signaling modulator 3  Rutbc3  RUN and TBC1 domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rutbc3  RUN and TBC1 domain containing 3  bdif-1  hypothetical protein  Symbol and Name updated 1299863 APPROVED