Abcc12 (ATP binding cassette subfamily C member 12) - Rat Genome Database

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Gene: Abcc12 (ATP binding cassette subfamily C member 12) Rattus norvegicus
Analyze
Symbol: Abcc12
Name: ATP binding cassette subfamily C member 12
RGD ID: 735100
Description: Predicted to enable ABC-type transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in endoplasmic reticulum. Predicted to be active in membrane. Orthologous to human ABCC12 (ATP binding cassette subfamily C member 12); PARTICIPATES IN multidrug resistance-associated protein mediated transport pathway; INTERACTS WITH atrazine; bisphenol A; choline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-binding cassette protein C12; ATP-binding cassette protein C12 variant A; ATP-binding cassette sub-family C member 12; ATP-binding cassette transporter sub-family C member 12; ATP-binding cassette, sub-family C (CFTR/MRP), member 12; ATP-binding cassette, subfamily C (CFTR/MRP), member 12; multidrug resistance-associated protein 9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81936,722,550 - 36,798,868 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1936,722,575 - 36,793,993 (+)EnsemblGRCr8
mRatBN7.21920,549,298 - 20,621,991 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1920,549,405 - 20,620,734 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1922,234,945 - 22,302,213 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01927,429,457 - 27,496,732 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01930,392,245 - 30,459,522 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01921,541,324 - 21,612,757 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)Ensemblrn6Rnor6.0
Rnor_5.01932,551,209 - 32,622,321 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41921,889,228 - 21,962,766 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1920,420,742 - 20,491,622 (+)NCBICelera
RGSC_v3.11921,894,053 - 21,967,592 (+)NCBI
Cytogenetic Map19p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12. Shimizu H, etal., Gene 2003 May 22;310:17-28.
Additional References at PubMed
PMID:18614015  


Genomics

Comparative Map Data
Abcc12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81936,722,550 - 36,798,868 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1936,722,575 - 36,793,993 (+)EnsemblGRCr8
mRatBN7.21920,549,298 - 20,621,991 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1920,549,405 - 20,620,734 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1922,234,945 - 22,302,213 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01927,429,457 - 27,496,732 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01930,392,245 - 30,459,522 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01921,541,324 - 21,612,757 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)Ensemblrn6Rnor6.0
Rnor_5.01932,551,209 - 32,622,321 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41921,889,228 - 21,962,766 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1920,420,742 - 20,491,622 (+)NCBICelera
RGSC_v3.11921,894,053 - 21,967,592 (+)NCBI
Cytogenetic Map19p11NCBI
ABCC12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381648,080,882 - 48,155,993 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1648,080,882 - 48,156,018 (-)Ensemblhg38GRCh38
GRCh371648,114,793 - 48,189,904 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361646,674,385 - 46,738,182 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341646,674,384 - 46,738,182NCBI
Celera1632,624,011 - 32,687,808 (-)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1634,007,046 - 34,070,841 (-)NCBIHuRef
CHM1_11649,524,782 - 49,588,575 (-)NCBICHM1_1
T2T-CHM13v2.01653,877,688 - 53,952,799 (-)NCBIT2T-CHM13v2.0
Abcc12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39887,231,197 - 87,307,317 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl887,208,889 - 87,307,315 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38886,504,568 - 86,580,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl886,482,260 - 86,580,686 (-)Ensemblmm10GRCm38
MGSCv37889,028,740 - 89,090,489 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36889,394,946 - 89,456,695 (-)NCBIMGSCv36mm8
Celera890,773,129 - 90,826,830 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map842.06NCBI
Abcc12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554747,166,150 - 7,238,033 (+)Ensembl
ChiLan1.0NW_0049554747,166,148 - 7,238,013 (+)NCBIChiLan1.0ChiLan1.0
ABCC12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21857,542,334 - 57,619,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11663,447,492 - 63,524,744 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01628,352,284 - 28,425,135 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11647,243,900 - 47,316,549 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1647,244,280 - 47,306,984 (-)EnsemblpanPan2panpan1.1
ABCC12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1266,885,272 - 66,967,963 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl266,885,042 - 66,968,060 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha263,461,458 - 63,544,137 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0267,443,767 - 67,526,459 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,443,562 - 67,526,556 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1264,256,791 - 64,339,454 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0265,280,662 - 65,363,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,168,371 - 66,251,101 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Abcc12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934958,188,099 - 58,257,885 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364751,331,887 - 1,391,535 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364751,331,887 - 1,391,535 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCC12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl636,557,290 - 36,649,715 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1636,559,645 - 36,653,044 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ABCC12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1533,883,283 - 33,946,742 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl533,883,290 - 33,945,808 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604742,582,955 - 42,646,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcc12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249141,732,060 - 1,795,027 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249141,731,541 - 1,806,400 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Abcc12
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11713,836,575 - 13,907,935 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Abcc12
605 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:47
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000021095, ENSRNOT00000042077
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
2 3 18 73 35 32 19 10 19 4 84 38 65 23 69 13 4 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_199377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY188179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY188180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000021095   ⟹   ENSRNOP00000021095
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1936,722,575 - 36,793,993 (+)Ensembl
mRatBN7.2 Ensembl1920,549,405 - 20,620,734 (+)Ensembl
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000042077   ⟹   ENSRNOP00000044842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1936,722,657 - 36,793,727 (+)Ensembl
mRatBN7.2 Ensembl1920,549,405 - 20,620,492 (+)Ensembl
Rnor_6.0 Ensembl1921,541,742 - 21,612,527 (+)Ensembl
RefSeq Acc Id: NM_199377   ⟹   NP_955409
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,657 - 36,793,727 (+)NCBI
mRatBN7.21920,549,405 - 20,620,492 (+)NCBI
Rnor_6.01921,541,742 - 21,612,527 (+)NCBI
Rnor_5.01932,551,209 - 32,622,321 (+)NCBI
RGSC_v3.41921,889,228 - 21,962,766 (+)RGD
Celera1920,420,742 - 20,491,622 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255241   ⟹   XP_006255303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,793,999 (+)NCBI
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
Rnor_6.01921,541,326 - 21,612,757 (+)NCBI
Rnor_5.01932,551,209 - 32,622,321 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772375   ⟹   XP_008770597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,793,999 (+)NCBI
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
Rnor_6.01921,541,325 - 21,612,757 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772376   ⟹   XP_008770598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,793,999 (+)NCBI
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
Rnor_6.01921,541,326 - 21,612,757 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097573   ⟹   XP_038953501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,793,999 (+)NCBI
mRatBN7.21920,549,298 - 20,620,761 (+)NCBI
RefSeq Acc Id: XM_039097575   ⟹   XP_038953503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,781,518 (+)NCBI
mRatBN7.21920,549,298 - 20,608,278 (+)NCBI
RefSeq Acc Id: XM_039097576   ⟹   XP_038953504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,781,565 (+)NCBI
mRatBN7.21920,549,298 - 20,608,330 (+)NCBI
RefSeq Acc Id: XM_039097577   ⟹   XP_038953505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,745,450 - 36,793,999 (+)NCBI
mRatBN7.21920,572,205 - 20,620,761 (+)NCBI
RefSeq Acc Id: XM_063277869   ⟹   XP_063133939
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,735,581 - 36,793,999 (+)NCBI
RefSeq Acc Id: XM_063277870   ⟹   XP_063133940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,738,641 - 36,793,999 (+)NCBI
RefSeq Acc Id: XR_005496627
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,798,868 (+)NCBI
mRatBN7.21920,549,298 - 20,621,991 (+)NCBI
RefSeq Acc Id: XR_005496628
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81936,722,550 - 36,793,021 (+)NCBI
mRatBN7.21920,549,298 - 20,619,790 (+)NCBI
RefSeq Acc Id: NP_955409   ⟸   NM_199377
- UniProtKB: Q6Y305 (UniProtKB/Swiss-Prot),   Q6Y306 (UniProtKB/Swiss-Prot),   D3ZIZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255303   ⟸   XM_006255241
- Peptide Label: isoform X3
- UniProtKB: D3ZIZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770597   ⟸   XM_008772375
- Peptide Label: isoform X1
- UniProtKB: D3ZIZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770598   ⟸   XM_008772376
- Peptide Label: isoform X2
- UniProtKB: D3ZIZ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021095   ⟸   ENSRNOT00000021095
Ensembl Acc Id: ENSRNOP00000044842   ⟸   ENSRNOT00000042077
RefSeq Acc Id: XP_038953501   ⟸   XM_039097573
- Peptide Label: isoform X4
- UniProtKB: D3ZIZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953504   ⟸   XM_039097576
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953503   ⟸   XM_039097575
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953505   ⟸   XM_039097577
- Peptide Label: isoform X8
- UniProtKB: A6KDC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133939   ⟸   XM_063277869
- Peptide Label: isoform X5
- UniProtKB: A6KDC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133940   ⟸   XM_063277870
- Peptide Label: isoform X7
- UniProtKB: A6KDC5 (UniProtKB/TrEMBL)
Protein Domains
ABC transmembrane type-1   ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6Y306-F1-model_v2 AlphaFold Q6Y306 1-1366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700987
Promoter ID:EPDNEW_R11510
Type:single initiation site
Name:Abcc12_1
Description:ATP binding cassette subfamily C member 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01921,541,691 - 21,541,751EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735100 AgrOrtholog
BioCyc Gene G2FUF-6226 BioCyc
Ensembl Genes ENSRNOG00000015666 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000021095 ENTREZGENE
  ENSRNOT00000042077 ENTREZGENE
Gene3D-CATH 1.20.1560.10 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  ABC1_TM_dom UniProtKB/Swiss-Prot
  ABC1_TM_sf UniProtKB/Swiss-Prot
  ABC_transporter-like UniProtKB/Swiss-Prot
  ABC_transporter_C UniProtKB/Swiss-Prot
  ABC_transporter_CS UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:291923 UniProtKB/Swiss-Prot
NCBI Gene 291923 ENTREZGENE
PANTHER ATP-BINDING CASSETTE SUB-FAMILY C UniProtKB/Swiss-Prot
  PTHR24223:SF10 UniProtKB/Swiss-Prot
Pfam ABC_membrane UniProtKB/Swiss-Prot
  ABC_tran UniProtKB/Swiss-Prot
PhenoGen Abcc12 PhenoGen
PROSITE ABC_TM1F UniProtKB/Swiss-Prot
  ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015666 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
  SSF90123 UniProtKB/Swiss-Prot
UniProt A6KDC5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIZ6 ENTREZGENE, UniProtKB/TrEMBL
  F1M7G9_RAT UniProtKB/TrEMBL
  MRP9_RAT UniProtKB/Swiss-Prot
  Q6Y305 ENTREZGENE
  Q6Y306 ENTREZGENE
UniProt Secondary Q6Y305 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Abcc12  ATP binding cassette subfamily C member 12  Abcc12  ATP-binding cassette, subfamily C (CFTR/MRP), member 12  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-16 Abcc12  ATP-binding cassette, subfamily C (CFTR/MRP), member 12  Abcc12  ATP-binding cassette, sub-family C (CFTR/MRP), member 12  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Abcc12  ATP-binding cassette, sub-family C (CFTR/MRP), member 12    ATP-binding cassette protein C12  Name updated 1299863 APPROVED