Wdr12 (WD repeat domain 12) - Rat Genome Database

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Gene: Wdr12 (WD repeat domain 12) Rattus norvegicus
Analyze
Symbol: Wdr12
Name: WD repeat domain 12
RGD ID: 735072
Description: Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and regulation of cell cycle. Predicted to act upstream of or within Notch signaling pathway. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Orthologous to human WDR12 (WD repeat domain 12); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ribosome biogenesis protein WDR12; WD repeat-containing protein 12
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,969,547 - 68,996,811 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl968,969,547 - 68,996,811 (-)EnsemblGRCr8
mRatBN7.2961,475,498 - 61,502,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,475,517 - 61,502,469 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx969,976,060 - 70,003,966 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,091,621 - 75,119,527 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,410,328 - 73,438,234 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,851,499 - 66,878,534 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,851,940 - 66,877,972 (-)Ensemblrn6Rnor6.0
Rnor_5.0966,665,603 - 66,691,634 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4958,614,192 - 58,641,597 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera958,910,009 - 58,934,061 (-)NCBICelera
RGSC_v3.1958,761,173 - 58,788,579 (-)NCBI
Cytogenetic Map9q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
Benoxacor  (ISO)
benzatropine  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
decabromodiphenyl ether  (EXP)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
enzalutamide  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
FR900359  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (IEA,ISO,ISS)
nucleoplasm  (IEA,ISO,ISS)
nucleus  (IEA,ISO)
PeBoW complex  (IBA,IEA,ISO,ISS)
preribosome, large subunit precursor  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Wdr12, a mouse gene encoding a novel WD-Repeat Protein with a notchless-like amino-terminal domain. Nal B, etal., Genomics 2002 Jan;79(1):77-86.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:16043514   PMID:16738141   PMID:17353269   PMID:25915632  


Genomics

Comparative Map Data
Wdr12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,969,547 - 68,996,811 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl968,969,547 - 68,996,811 (-)EnsemblGRCr8
mRatBN7.2961,475,498 - 61,502,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,475,517 - 61,502,469 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx969,976,060 - 70,003,966 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,091,621 - 75,119,527 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,410,328 - 73,438,234 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,851,499 - 66,878,534 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,851,940 - 66,877,972 (-)Ensemblrn6Rnor6.0
Rnor_5.0966,665,603 - 66,691,634 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4958,614,192 - 58,641,597 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera958,910,009 - 58,934,061 (-)NCBICelera
RGSC_v3.1958,761,173 - 58,788,579 (-)NCBI
Cytogenetic Map9q32NCBI
WDR12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,874,261 - 202,911,673 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,874,261 - 203,014,798 (-)Ensemblhg38GRCh38
GRCh372203,738,984 - 203,776,396 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362203,453,575 - 203,484,639 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342203,570,835 - 203,601,900NCBI
Celera2197,498,009 - 197,529,627 (-)NCBICelera
Cytogenetic Map2q33.2NCBI
HuRef2195,592,185 - 195,623,787 (-)NCBIHuRef
CHM1_12203,751,915 - 203,783,565 (-)NCBICHM1_1
T2T-CHM13v2.02203,355,718 - 203,393,126 (-)NCBIT2T-CHM13v2.0
Wdr12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39160,110,520 - 60,137,659 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl160,108,944 - 60,137,804 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38160,071,361 - 60,098,500 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl160,069,785 - 60,098,645 (-)Ensemblmm10GRCm38
MGSCv37160,133,712 - 60,154,722 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36160,021,414 - 60,042,424 (-)NCBIMGSCv36mm8
Celera160,592,628 - 60,613,639 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.45NCBI
Wdr12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545711,947,915 - 11,971,805 (+)Ensembl
ChiLan1.0NW_00495545711,947,816 - 11,970,066 (+)NCBIChiLan1.0ChiLan1.0
WDR12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213105,483,663 - 105,514,951 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B105,496,501 - 105,530,558 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B90,112,037 - 90,145,520 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B208,260,696 - 208,292,604 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B208,260,696 - 208,291,783 (-)EnsemblpanPan2panpan1.1
WDR12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,762,598 - 11,787,025 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,762,777 - 11,786,933 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3712,646,140 - 12,670,826 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03711,699,520 - 11,724,283 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,695,221 - 11,723,916 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,655,780 - 11,680,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,627,136 - 11,651,850 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,621,045 - 11,645,767 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Wdr12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,960,936 - 159,988,288 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,931,183 - 1,958,215 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,931,221 - 1,958,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15106,380,755 - 106,410,416 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115106,380,748 - 106,410,723 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,834,705 - 117,860,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDR12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11088,616,540 - 88,649,743 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1088,616,797 - 88,649,418 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040110,738,393 - 110,768,906 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476513,504,533 - 13,531,200 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476513,504,347 - 13,532,418 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Wdr12
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v156,293,996 - 6,314,230 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Wdr12
308 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:69
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000023463
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
1578659Tspe1Trichinella spiralis expulsion QTL 14.8parasite quantity (VT:0010441)logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)96887549773185088Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
RH143036  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8968,973,871 - 68,974,050 (+)Marker Load Pipeline
mRatBN7.2961,479,822 - 61,480,001 (+)MAPPERmRatBN7.2
Rnor_6.0966,855,824 - 66,856,002NCBIRnor6.0
Rnor_5.0966,669,488 - 66,669,666UniSTSRnor5.0
RGSC_v3.4958,618,077 - 58,618,255UniSTSRGSC3.4
Celera958,913,894 - 58,914,072UniSTS
RH 3.4 Map9505.6UniSTS
Cytogenetic Map9q31UniSTS
RH132498  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,475,593 - 61,475,812 (+)MAPPERmRatBN7.2
Rnor_6.0966,851,595 - 66,851,813NCBIRnor6.0
Rnor_5.0966,665,259 - 66,665,477UniSTSRnor5.0
RGSC_v3.4958,613,848 - 58,614,066UniSTSRGSC3.4
Celera958,909,665 - 58,909,883UniSTS
RH 3.4 Map9514.4UniSTS
Cytogenetic Map9q31UniSTS
RH141263  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2953,338,478 - 53,338,658 (+)MAPPERmRatBN7.2
Rnor_6.0958,313,494 - 58,313,673NCBIRnor6.0
Rnor_5.0958,006,174 - 58,006,353UniSTSRnor5.0
RGSC_v3.4950,596,965 - 50,597,144UniSTSRGSC3.4
Celera950,906,476 - 50,906,655UniSTS
Cytogenetic Map9q22UniSTS
Cytogenetic Map9q31UniSTS
UniSTS:237290  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,480,874 - 61,481,369 (+)MAPPERmRatBN7.2
mRatBN7.2953,338,691 - 53,338,954 (+)MAPPERmRatBN7.2
Rnor_6.0966,856,876 - 66,857,370NCBIRnor6.0
Rnor_6.0958,313,707 - 58,313,969NCBIRnor6.0
Rnor_5.0966,670,540 - 66,671,034UniSTSRnor5.0
RGSC_v3.4950,597,178 - 50,597,547UniSTSRGSC3.4
RGSC_v3.4958,619,129 - 58,619,623UniSTSRGSC3.4
Celera958,914,946 - 58,915,440UniSTS
Cytogenetic Map9q22UniSTS
Cytogenetic Map9q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000023463   ⟹   ENSRNOP00000023463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,969,547 - 68,996,811 (-)Ensembl
mRatBN7.2 Ensembl961,475,517 - 61,502,469 (-)Ensembl
Rnor_6.0 Ensembl966,851,940 - 66,877,972 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111689   ⟹   ENSRNOP00000078380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,969,547 - 68,993,685 (-)Ensembl
mRatBN7.2 Ensembl961,475,517 - 61,499,636 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000152693   ⟹   ENSRNOP00000108563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,971,740 - 68,996,811 (-)Ensembl
RefSeq Acc Id: NM_001393868   ⟹   NP_001380797
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,547 - 68,996,811 (-)NCBI
mRatBN7.2961,475,498 - 61,502,762 (-)NCBI
RefSeq Acc Id: NM_001393869   ⟹   NP_001380798
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,547 - 68,996,811 (-)NCBI
mRatBN7.2961,475,498 - 61,502,762 (-)NCBI
RefSeq Acc Id: NM_199410   ⟹   NP_955442
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,547 - 68,996,811 (-)NCBI
mRatBN7.2961,475,498 - 61,502,762 (-)NCBI
Rnor_6.0966,851,939 - 66,877,970 (-)NCBI
Rnor_5.0966,665,603 - 66,691,634 (-)NCBI
RGSC_v3.4958,614,192 - 58,641,597 (-)RGD
Celera958,910,009 - 58,934,061 (-)RGD
Sequence:
RefSeq Acc Id: XM_017596520   ⟹   XP_017452009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,987 - 68,996,469 (-)NCBI
mRatBN7.2961,475,498 - 61,502,425 (-)NCBI
Rnor_6.0966,851,499 - 66,878,441 (-)NCBI
Sequence:
RefSeq Acc Id: NP_955442   ⟸   NM_199410
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452009   ⟸   XM_017596520
- Peptide Label: isoform X1
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023463   ⟸   ENSRNOT00000023463
Ensembl Acc Id: ENSRNOP00000078380   ⟸   ENSRNOT00000111689
RefSeq Acc Id: NP_001380798   ⟸   NM_001393869
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380797   ⟸   NM_001393868
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108563   ⟸   ENSRNOT00000152693
Protein Domains
NLE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61480-F1-model_v2 AlphaFold P61480 1-423 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696705
Promoter ID:EPDNEW_R7230
Type:single initiation site
Name:Wdr12_1
Description:WD repeat domain 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0966,877,992 - 66,878,052EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735072 AgrOrtholog
BioCyc Gene G2FUF-27385 BioCyc
Ensembl Genes ENSRNOG00000017340 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000023463 ENTREZGENE
  ENSRNOT00000023463.6 UniProtKB/Swiss-Prot
  ENSRNOT00000111689 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6920424 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  NLE UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
  WDR12/Ytm1 UniProtKB/Swiss-Prot
KEGG Report rno:363237 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72960 IMAGE-MGC_LOAD
NCBI Gene 363237 ENTREZGENE
PANTHER RIBOSOME BIOGENESIS PROTEIN WDR12 UniProtKB/Swiss-Prot
  WD40 REPEAT PROTEIN 12, 37 UniProtKB/Swiss-Prot
Pfam NLE UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Wdr12 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017340 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8I5ZKS8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LY42_RAT UniProtKB/TrEMBL
  A6IPC1 ENTREZGENE, UniProtKB/TrEMBL
  P61480 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Wdr12  WD repeat domain 12      Symbol and Name status set to approved 1299863 APPROVED