Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mpped2 | Rat | 17beta-estradiol | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of MPPED2 mRNA; EGF protein inhibits the more ... | CTD | PMID:19619570|PMID:24758408 | Mpped2 | Rat | 17beta-estradiol | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of MPPED2 mRNA | CTD | PMID:18191855 | Mpped2 | Rat | 17beta-estradiol | increases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of MPPED2 mRNA | CTD | PMID:19619570|PMID:21185374|PMID:24758408 | Mpped2 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of MPPED2 mRNA | CTD | PMID:31388691 | Mpped2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of MPPED2 mRNA | CTD | PMID:19619570 | Mpped2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MPPED2 mRNA | CTD | PMID:34747641 | Mpped2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MPPED2 mRNA | CTD | PMID:32109520 | Mpped2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MPPED2 mRNA | CTD | PMID:19619570 | Mpped2 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MPPED2 mRNA | CTD | PMID:23196670|PMID:32119087 | Mpped2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of MPPED2 mRNA | CTD | PMID:30951980 | Mpped2 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of MPPED2 mRNA | CTD | PMID:24780913 | Mpped2 | Rat | aflatoxin B1 | increases methylation | ISO | MPPED2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of MPPED2 3' UTR | CTD | PMID:30157460 | Mpped2 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | MPPED2 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of MPPED2 intron | CTD | PMID:30157460 | Mpped2 | Rat | all-trans-retinoic acid | increases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MPPED2 mRNA | CTD | PMID:21934132|PMID:23724009 | Mpped2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of MPPED2 mRNA | CTD | PMID:16483693 | Mpped2 | Rat | antirheumatic drug | increases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of MPPED2 mRNA | CTD | PMID:24449571 | Mpped2 | Rat | arsenous acid | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of MPPED2 mRNA | CTD | PMID:26705709 | Mpped2 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of MPPED2 mRNA | CTD | PMID:36841081 | Mpped2 | Rat | belinostat | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | belinostat results in decreased expression of MPPED2 mRNA | CTD | PMID:26272509 | Mpped2 | Rat | belinostat | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Mpped2 | Rat | benzo[a]pyrene | increases methylation | ISO | MPPED2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MPPED2 promoter | CTD | PMID:27901495 | Mpped2 | Rat | benzo[a]pyrene | affects methylation | ISO | MPPED2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MPPED2 5' UTR; Benzo(a)pyrene affects the methylation of MPPED2 exon; more ... | CTD | PMID:27901495|PMID:30157460 | Mpped2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MPPED2 mRNA | CTD | PMID:25181051 | Mpped2 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MPPED2 gene | CTD | PMID:28505145 | Mpped2 | Rat | buta-1,3-diene | decreases expression | ISO | Mpped2 (Mus musculus) | 6480464 | 1,3-butadiene results in decreased expression of MPPED2 mRNA | CTD | PMID:29038090 | Mpped2 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Mpped2 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of MPPED2 intron | CTD | PMID:28392331 | Mpped2 | Rat | carbon nanotube | decreases expression | ISO | Mpped2 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of MPPED2 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:25620056 | Mpped2 | Rat | CGP 52608 | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MPPED2 gene] | CTD | PMID:28238834 | Mpped2 | Rat | chlorpyrifos | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MPPED2 mRNA | CTD | PMID:37019170 | Mpped2 | Rat | coumestrol | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of MPPED2 mRNA | CTD | PMID:19167446 | Mpped2 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of MPPED2 mRNA | CTD | PMID:26577399 | Mpped2 | Rat | diarsenic trioxide | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of MPPED2 mRNA | CTD | PMID:26705709 | Mpped2 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of MPPED2 mRNA | CTD | PMID:21266533 | Mpped2 | Rat | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of MPPED2 mRNA | CTD | PMID:21551480 | Mpped2 | Rat | dorsomorphin | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Mpped2 | Rat | doxorubicin | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MPPED2 mRNA | CTD | PMID:29803840 | Mpped2 | Rat | doxorubicin | decreases expression | ISO | Mpped2 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of MPPED2 mRNA | CTD | PMID:39631538 | Mpped2 | Rat | entinostat | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | entinostat results in decreased expression of MPPED2 mRNA | CTD | PMID:26272509 | Mpped2 | Rat | entinostat | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Mpped2 | Rat | epoxiconazole | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of MPPED2 mRNA | CTD | PMID:35436446 | Mpped2 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of MPPED2 mRNA | CTD | PMID:22061828 | Mpped2 | Rat | hexane | decreases methylation | EXP | | 6480464 | n-hexane results in decreased methylation of MPPED2 promoter | CTD | PMID:23740543 | Mpped2 | Rat | methylmercury chloride | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of MPPED2 mRNA | CTD | PMID:23179753|PMID:26272509|PMID:28001369 | Mpped2 | Rat | nickel atom | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of MPPED2 mRNA | CTD | PMID:24768652|PMID:25583101 | Mpped2 | Rat | okadaic acid | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of MPPED2 mRNA | CTD | PMID:38832940 | Mpped2 | Rat | oxybenzone | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | oxybenzone results in increased expression of MPPED2 mRNA | CTD | PMID:39343157 | Mpped2 | Rat | ozone | multiple interactions | ISO | Mpped2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:27106289|PMID:34911549 | Mpped2 | Rat | panobinostat | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Mpped2 | Rat | panobinostat | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of MPPED2 mRNA | CTD | PMID:26272509 | Mpped2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of MPPED2 mRNA | CTD | PMID:33387578 | Mpped2 | Rat | raloxifene | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA | CTD | PMID:19059307 | Mpped2 | Rat | resveratrol | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of MPPED2 mRNA | CTD | PMID:19167446 | Mpped2 | Rat | rotenone | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of MPPED2 protein | CTD | PMID:39603559 | Mpped2 | Rat | SB 431542 | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Mpped2 | Rat | silver atom | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | Silver results in increased expression of MPPED2 mRNA | CTD | PMID:27131904 | Mpped2 | Rat | silver(0) | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | Silver results in increased expression of MPPED2 mRNA | CTD | PMID:27131904 | Mpped2 | Rat | sodium arsenite | affects methylation | ISO | MPPED2 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of MPPED2 gene | CTD | PMID:28589171 | Mpped2 | Rat | sodium arsenite | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of MPPED2 mRNA | CTD | PMID:39719251 | Mpped2 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of MPPED2 mRNA | CTD | PMID:19281266 | Mpped2 | Rat | sunitinib | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MPPED2 mRNA | CTD | PMID:31533062 | Mpped2 | Rat | tamoxifen | multiple interactions | ISO | MPPED2 (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA | CTD | PMID:19059307 | Mpped2 | Rat | titanium dioxide | increases expression | ISO | Mpped2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of MPPED2 mRNA | CTD | PMID:23557971 | Mpped2 | Rat | titanium dioxide | decreases methylation | ISO | Mpped2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of MPPED2 promoter | CTD | PMID:35295148 | Mpped2 | Rat | titanium dioxide | decreases expression | ISO | Mpped2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of MPPED2 mRNA | CTD | PMID:29264374 | Mpped2 | Rat | valproic acid | decreases methylation | ISO | MPPED2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of MPPED2 gene | CTD | PMID:29154799 | Mpped2 | Rat | valproic acid | decreases expression | ISO | Mpped2 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of MPPED2 mRNA | CTD | PMID:21427059 | Mpped2 | Rat | valproic acid | decreases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MPPED2 mRNA | CTD | PMID:23179753|PMID:28001369 | Mpped2 | Rat | valproic acid | increases expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MPPED2 mRNA | CTD | PMID:23179753|PMID:24383497 | Mpped2 | Rat | valproic acid | affects expression | ISO | MPPED2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MPPED2 mRNA | CTD | PMID:25979313 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















