Cct3 (chaperonin containing TCP1 subunit 3) - Rat Genome Database

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Gene: Cct3 (chaperonin containing TCP1 subunit 3) Rattus norvegicus
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Symbol: Cct3
Name: chaperonin containing TCP1 subunit 3
RGD ID: 735038
Description: Predicted to enable protein folding chaperone and unfolded protein binding activity. Predicted to be involved in several processes, including chaperone mediated protein folding independent of cofactor; positive regulation of protein localization to Cajal body; and positive regulation of telomerase RNA localization to Cajal body. Predicted to act upstream of or within binding activity of sperm to zona pellucida. Predicted to be located in cell body and microtubule. Predicted to be part of chaperonin-containing T-complex and zona pellucida receptor complex. Orthologous to human CCT3 (chaperonin containing TCP1 subunit 3); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CCT-gamma; chaperonin containing Tcp1, subunit 3 (gamma); chaperonin subunit 3 (gamma); MGC72950; T-complex protein 1 subunit gamma; TCP-1-gamma
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Cct3-ps2   Cct3-ps3  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82176,063,529 - 176,088,180 (+)NCBIGRCr8
mRatBN7.22173,765,701 - 173,790,353 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,765,698 - 173,790,757 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,910,314 - 180,934,758 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,932,672 - 178,957,116 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02173,532,533 - 173,557,196 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02187,669,051 - 187,693,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,668,796 - 187,693,610 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,072,068 - 207,096,553 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,381,044 - 180,434,152 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12180,331,149 - 180,384,258 (+)NCBI
Celera2167,711,584 - 167,735,276 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Cct3RatCharcot-Marie-Tooth disease type 2  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 2ClinVarPMID:18585512 more ...
Cct3Ratgastrointestinal stromal tumor  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Cct3Ratimmunodeficiency 42  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete RORgamma receptor deficiencyClinVarPMID:28492532
Cct3RatMHC class II deficiency  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:28492532
Cct3RatNEURODEVELOPMENTAL DISORDER WITH SPEECH OR VISUAL IMPAIRMENT AND BRAIN HYPOMYELINATION  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: NEURODEVELOPMENTAL DISORDER WITH SPEECH OR VISUAL IMPAIRMENT AND BRAIN HYPOMYELINATIONClinVarPMID:25741868 and PMID:39480921
Cct3Ratparathyroid carcinoma  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
Cct3Ratsevere congenital neutropenia 3  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Kostmann syndromeClinVarPMID:28492532
Cct3Ratsevere congenital neutropenia 5  ISOCCT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital neutropenia-myelofibrosis-nephromegaly syndromeClinVarPMID:28492532
Object Symbol
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Original Reference(s)
Cct3RatChemical and Drug Induced Liver Injury  ISOCCT3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25231249
Cct3Rathuman immunodeficiency virus infectious disease  ISOCCT3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15308739
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Original Reference(s)
Cct3RatNEURODEVELOPMENTAL DISORDER WITH SPEECH OR VISUAL IMPAIRMENT AND BRAIN HYPOMYELINATION  ISOCCT3 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Cct3Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of CCT3 mRNA]CTDPMID:31150632
Cct3Rat(1->4)-beta-D-glucan multiple interactionsISOCct3 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CCT3 mRNACTDPMID:36331819
Cct3Rat1,2-dimethylhydrazine multiple interactionsISOCct3 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of CCT3 mRNA]CTDPMID:22206623
Cct3Rat1,2-dimethylhydrazine increases expressionISOCct3 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of CCT3 mRNACTDPMID:22206623
Cct3Rat1-chloro-2,4-dinitrobenzene affects bindingISOCCT3 (Homo sapiens)6480464Dinitrochlorobenzene binds to CCT3 proteinCTDPMID:32991956
Cct3Rat17alpha-ethynylestradiol affects expressionISOCct3 (Mus musculus)6480464Ethinyl Estradiol affects the expression of CCT3 mRNACTDPMID:17555576
Cct3Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of CCT3 mRNACTDPMID:16174780
Cct3Rat17alpha-ethynylestradiol multiple interactionsISOCct3 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCT3 mRNACTDPMID:17942748
Cct3Rat17alpha-ethynylestradiol increases expressionISOCct3 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of CCT3 mRNACTDPMID:16174780 and PMID:17942748
Cct3Rat17beta-estradiol affects expressionISOCct3 (Mus musculus)6480464Estradiol affects the expression of CCT3 mRNACTDPMID:15598610
Cct3Rat17beta-estradiol increases expressionISOCct3 (Mus musculus)6480464Estradiol results in increased expression of CCT3 mRNACTDPMID:39298647
Cct3Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of CCT3 proteinCTDPMID:32145629
Cct3Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOCct3 (Mus musculus)64804642 more ...CTDPMID:30294300
Cct3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOCct3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of CCT3 mRNACTDPMID:17942748 and PMID:18796159
Cct3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCct3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CCT3 mRNACTDPMID:21570461
Cct3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of CCT3 proteinCTDPMID:16548065 and PMID:19201780
Cct3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCct3 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCT3 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCT3 promoter]CTDPMID:17942748 and PMID:19654925
Cct3Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expressionEXP 64804642 more ...CTDPMID:19954255
Cct3Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expressionEXP 64804642 more ...CTDPMID:19954255
Cct3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of CCT3 mRNACTDPMID:21346803

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Biological Process
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Original Reference(s)
Cct3Ratbinding of sperm to zona pellucida acts_upstream_of_or_withinIEAUniProtKB:P80318 and ensembl:ENSMUSP000000014521600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratbinding of sperm to zona pellucida acts_upstream_of_or_withinISOCct3 (Mus musculus)1624291 PMID:21880732RGDPMID:21880732
Cct3Ratchaperone mediated protein folding independent of cofactor involved_inIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratchaperone-mediated protein folding involved_inISOCCT3 (Homo sapiens)1624291 PMID:22133715RGDPMID:22133715
Cct3Ratchaperone-mediated protein folding involved_inIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratpositive regulation of protein localization to Cajal body involved_inISOCCT3 (Homo sapiens)9068941 PMID:25467444BHF-UCLPMID:25467444
Cct3Ratpositive regulation of telomerase RNA localization to Cajal body involved_inISOCCT3 (Homo sapiens)9068941 PMID:25467444BHF-UCLPMID:25467444
Cct3Ratpositive regulation of telomere maintenance via telomerase acts_upstream_ofISOCCT3 (Homo sapiens)1624291 PMID:25467444RGDPMID:25467444
Cct3Ratpositive regulation of telomere maintenance via telomerase acts_upstream_ofIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratprotein folding involved_inIEAInterPro:IPR002194 and InterPro:IPR0127191600115GO_REF:0000002InterProGO_REF:0000002
Cct3Ratprotein folding involved_inISOCCT3 (Homo sapiens)1624291 PMID:25467444 and PMID:30955883RGDPMID:25467444 and PMID:30955883
Cct3Ratprotein folding involved_inIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratprotein folding involved_inIBAPANTHER:PTN004253040 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cct3Ratprotein stabilization involved_inISOCCT3 (Homo sapiens)1624291 PMID:25467444RGDPMID:25467444
Cct3Ratprotein stabilization involved_inIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratsexual reproduction involved_inIEAARBA:ARBA000287151600115GO_REF:0000117UniProtGO_REF:0000117
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Cellular Component
1 to 15 of 15 rows

  
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Original Reference(s)
Cct3Ratcell body located_inISOCct3 (Mus musculus)1624291 PMID:21880732RGDPMID:21880732
Cct3Ratcell body located_inIEAUniProtKB:P80318 and ensembl:ENSMUSP000000014521600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratchaperonin-containing T-complex part_ofISOCCT3 (Homo sapiens)1624291 PMID:22133715 more ...RGDPMID:22133715 more ...
Cct3Ratchaperonin-containing T-complex part_ofISOCct3 (Mus musculus)1624291 PMID:7798195 more ...RGDPMID:7798195 more ...
Cct3Ratchaperonin-containing T-complex part_ofIEAUniProtKB:P80318 and ensembl:ENSMUSP000000014521600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratchaperonin-containing T-complex part_ofIBAMGI:104708 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cct3Ratchaperonin-containing T-complex part_ofIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratchaperonin-containing T-complex part_ofISSUniProtKB:Q3T0K21600115GO_REF:0000024UniProtGO_REF:0000024
Cct3Ratchaperonin-containing T-complex part_ofIEAARBA:ARBA000292731600115GO_REF:0000117UniProtGO_REF:0000117
Cct3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Cct3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Cct3Ratmicrotubule located_inISOCCT3 (Homo sapiens)1624291 PMID:21525035RGDPMID:21525035
Cct3Ratmicrotubule located_inIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratzona pellucida receptor complex part_ofISOCct3 (Mus musculus)1624291 PMID:21880732RGDPMID:21880732
Cct3Ratzona pellucida receptor complex part_ofIEAUniProtKB:P80318 and ensembl:ENSMUSP000000014521600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
1 to 11 of 11 rows

  
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Original Reference(s)
Cct3RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Cct3RatATP binding enablesIEAInterPro:IPR002194 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Cct3RatATP hydrolysis activity enablesIEAInterPro:IPR002194 and InterPro:IPR0127191600115GO_REF:0000002InterProGO_REF:0000002
Cct3RatATP-dependent protein folding chaperone enablesIEAInterPro:IPR0179981600115GO_REF:0000002InterProGO_REF:0000002
Cct3Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Cct3Ratprotein binding enablesISOCCT3 (Homo sapiens)1624291UniProtKB:O15160 more ...RGDPMID:12620389 more ...
Cct3Ratprotein binding enablesISOCct3 (Mus musculus)1624291PR:E9Q9D5 more ...RGDPMID:23055941 more ...
Cct3Ratprotein folding chaperone enablesISOCCT3 (Homo sapiens)1624291 PMID:25467444 and PMID:30955883RGDPMID:25467444 and PMID:30955883
Cct3Ratprotein folding chaperone enablesIEAUniProtKB:P49368 and ensembl:ENSP000002956881600115GO_REF:0000107EnsemblGO_REF:0000107
Cct3Ratunfolded protein binding enablesIEAInterPro:IPR002194 and InterPro:IPR0127191600115GO_REF:0000002InterProGO_REF:0000002
Cct3Ratunfolded protein binding enablesIBAPANTHER:PTN004253040 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Structures and co-regulated expression of the genes encoding mouse cytosolic chaperonin CCT subunits. Kubota H, etal., Eur J Biochem 1999 Jun;262(2):492-500.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:7798195   PMID:7828721   PMID:7953530   PMID:15489334   PMID:16854843   PMID:17634366   PMID:19056867   PMID:20193073   PMID:20458337   PMID:21525035   PMID:21880732   PMID:22082260  
PMID:22681889   PMID:22871113   PMID:23011926   PMID:23533145   PMID:23716698   PMID:24625528   PMID:25002582   PMID:25467444   PMID:29476059   PMID:31904090   PMID:33450132  



Cct3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82176,063,529 - 176,088,180 (+)NCBIGRCr8
mRatBN7.22173,765,701 - 173,790,353 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,765,698 - 173,790,757 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,910,314 - 180,934,758 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,932,672 - 178,957,116 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02173,532,533 - 173,557,196 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02187,669,051 - 187,693,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,668,796 - 187,693,610 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,072,068 - 207,096,553 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,381,044 - 180,434,152 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12180,331,149 - 180,384,258 (+)NCBI
Celera2167,711,584 - 167,735,276 (+)NCBICelera
Cytogenetic Map2q34NCBI
CCT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,308,968 - 156,338,292 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,308,968 - 156,367,873 (-)EnsemblGRCh38hg38GRCh38
GRCh371156,278,759 - 156,308,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,545,376 - 154,574,819 (-)NCBINCBI36Build 36hg18NCBI36
Build 341153,091,832 - 153,121,121NCBI
Celera1129,351,733 - 129,381,131 (-)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1127,638,812 - 127,668,494 (-)NCBIHuRef
CHM1_11157,674,664 - 157,704,561 (-)NCBICHM1_1
T2T-CHM13v2.01155,447,437 - 155,476,903 (-)NCBIT2T-CHM13v2.0
Cct3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,204,442 - 88,229,073 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,204,423 - 88,229,074 (+)EnsemblGRCm39 Ensembl
GRCm38388,297,135 - 88,321,766 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,297,116 - 88,321,767 (+)EnsemblGRCm38mm10GRCm38
MGSCv37388,101,057 - 88,125,688 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,383,062 - 88,407,693 (+)NCBIMGSCv36mm8
Celera388,336,705 - 88,361,340 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.79NCBI
Cct3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,444,988 - 2,461,113 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,444,988 - 2,460,976 (-)NCBIChiLan1.0ChiLan1.0
CCT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2193,508,565 - 93,536,333 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1193,240,518 - 93,268,250 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,652,058 - 131,679,802 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,482,012 - 135,508,983 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,481,427 - 135,508,983 (-)Ensemblpanpan1.1panPan2
CCT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,566,274 - 41,583,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,566,292 - 41,584,863 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,054,446 - 41,072,072 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,431,013 - 41,448,650 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,431,096 - 41,449,272 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,212,433 - 41,230,036 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,265,635 - 41,283,249 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,549,686 - 41,567,311 (+)NCBIUU_Cfam_GSD_1.0
Cct3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,506,956 - 26,523,883 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365805,537,015 - 5,554,384 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365805,537,338 - 5,554,384 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,733,918 - 93,753,340 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,733,967 - 93,753,340 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,435,570 - 102,453,406 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,518,729 - 7,545,296 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl207,518,846 - 7,545,677 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660386,819,515 - 6,846,680 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248851,575,562 - 1,592,594 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248851,575,560 - 1,592,540 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Cct3
221 total Variants

Predicted Target Of
Summary Value
Count of predictions:187
Count of miRNA genes:140
Interacting mature miRNAs:149
Transcripts:ENSRNOT00000025824
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 73 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat

1 to 10 of 73 rows
RH129532  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22173,790,133 - 173,790,336 (+)MAPPERmRatBN7.2
Rnor_6.02187,693,391 - 187,693,593NCBIRnor6.0
Rnor_5.02207,096,334 - 207,096,536UniSTSRnor5.0
RGSC_v3.42180,433,933 - 180,434,135UniSTSRGSC3.4
Celera2167,735,057 - 167,735,259UniSTS
RH 3.4 Map21152.0UniSTS
Cytogenetic Map2q34UniSTS
RH129680  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22173,790,132 - 173,790,336 (+)MAPPERmRatBN7.2
Rnor_6.02187,693,390 - 187,693,593NCBIRnor6.0
Rnor_5.02207,096,333 - 207,096,536UniSTSRnor5.0
RGSC_v3.42180,433,932 - 180,434,135UniSTSRGSC3.4
Celera2167,735,056 - 167,735,259UniSTS
Cytogenetic Map2q34UniSTS
RH135214  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22173,769,826 - 173,770,043 (+)MAPPERmRatBN7.2
Rnor_6.02187,673,086 - 187,673,302NCBIRnor6.0
Rnor_5.02207,076,103 - 207,076,319UniSTSRnor5.0
RGSC_v3.42180,385,079 - 180,385,295UniSTSRGSC3.4
Celera2167,715,619 - 167,715,835UniSTS
RH 3.4 Map21148.91UniSTS
Cytogenetic Map2q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000025824   ⟹   ENSRNOP00000025824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,765,699 - 173,790,351 (+)Ensembl
Rnor_6.0 Ensembl2187,668,796 - 187,693,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2187,670,722 - 187,675,355 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,765,699 - 173,790,351 (+)Ensembl
Rnor_6.0 Ensembl2187,668,960 - 187,685,721 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2187,691,761 - 187,692,402 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2187,668,970 - 187,669,394 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110088   ⟹   ENSRNOP00000076951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,765,698 - 173,790,757 (+)Ensembl
RefSeq Acc Id: NM_199091   ⟹   NP_954522
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82176,063,529 - 176,088,180 (+)NCBI
mRatBN7.22173,765,701 - 173,790,353 (+)NCBI
Rnor_6.02187,669,051 - 187,693,610 (+)NCBI
Rnor_5.02207,072,068 - 207,096,553 (+)NCBI
RGSC_v3.42180,381,044 - 180,434,152 (+)RGD
Celera2167,711,584 - 167,735,276 (+)RGD
Sequence:
Protein RefSeqs NP_954522 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH63178 (Get FASTA)   NCBI Sequence Viewer  
  EDM00727 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025824.4
  ENSRNOP00000076951
GenBank Protein Q6P502 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_954522   ⟸   NM_199091
- UniProtKB: Q6P502 (UniProtKB/Swiss-Prot),   A6J662 (UniProtKB/TrEMBL),   A0A8I6GKA7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025824   ⟸   ENSRNOT00000025824
Ensembl Acc Id: ENSRNOP00000076951   ⟸   ENSRNOT00000110088

Name Modeler Protein Id AA Range Protein Structure
AF-Q6P502-F1-model_v2 AlphaFold Q6P502 1-545 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691433
Promoter ID:EPDNEW_R1956
Type:initiation region
Name:Cct3_1
Description:chaperonin containing TCP1 subunit 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02187,668,973 - 187,669,033EPDNEW


1 to 35 of 35 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-52493 BioCyc
Ensembl Genes ENSRNOG00000019090 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025824.7 UniProtKB/Swiss-Prot
  ENSRNOT00000110088 ENTREZGENE
Gene3D-CATH 1.10.560.10 UniProtKB/Swiss-Prot
  3.30.260.10 UniProtKB/Swiss-Prot
  3.50.7.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6890550 IMAGE-MGC_LOAD
InterPro Chap_CCT_gamma UniProtKB/Swiss-Prot
  Chaperone_TCP-1 UniProtKB/Swiss-Prot
  Chaperonin_TCP-1_CS UniProtKB/Swiss-Prot
  Cpn60/TCP-1 UniProtKB/Swiss-Prot
  GroEL-like_apical_dom_sf UniProtKB/Swiss-Prot
  GROEL-like_equatorial_sf UniProtKB/Swiss-Prot
  TCP-1-like_intermed_sf UniProtKB/Swiss-Prot
  TCP-1_chaperonin UniProtKB/Swiss-Prot
  thermosome_alpha UniProtKB/Swiss-Prot
KEGG Report rno:295230 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72950 IMAGE-MGC_LOAD
NCBI Gene 295230 ENTREZGENE
PANTHER PTHR11353 UniProtKB/Swiss-Prot
Pfam Cpn60_TCP1 UniProtKB/Swiss-Prot
PhenoGen Cct3 PhenoGen
PRINTS TCOMPLEXTCP1 UniProtKB/Swiss-Prot
PROSITE TCP1_1 UniProtKB/Swiss-Prot
  TCP1_2 UniProtKB/Swiss-Prot
  TCP1_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019090 RatGTEx
Superfamily-SCOP SSF48592 UniProtKB/Swiss-Prot
  SSF52029 UniProtKB/Swiss-Prot
  SSF54849 UniProtKB/Swiss-Prot
UniProt A0A8I5Y7A1_RAT UniProtKB/TrEMBL
  A0A8I6GKA7 ENTREZGENE, UniProtKB/TrEMBL
  A6J662 ENTREZGENE, UniProtKB/TrEMBL
  Q6P502 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 35 of 35 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Cct3  chaperonin containing TCP1 subunit 3  Cct3  chaperonin containing Tcp1, subunit 3 (gamma)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Cct3  chaperonin containing Tcp1, subunit 3 (gamma)  Cct3  chaperonin subunit 3 (gamma)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Cct3  chaperonin subunit 3 (gamma)    chaperonin containing TCP1, subunit 3 (gamma)  Name updated 1299863 APPROVED