Lhfpl4 (LHFPL tetraspan subfamily member 4) - Rat Genome Database

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Gene: Lhfpl4 (LHFPL tetraspan subfamily member 4) Rattus norvegicus
Analyze
Symbol: Lhfpl4
Name: LHFPL tetraspan subfamily member 4
RGD ID: 727967
Description: Enables GABA receptor binding activity. Predicted to be involved in several processes, including gamma-aminobutyric acid receptor clustering; neurotransmitter receptor localization to postsynaptic specialization membrane; and regulation of inhibitory synapse assembly. Located in inhibitory synapse. Orthologous to human LHFPL4 (LHFPL tetraspan subfamily member 4); INTERACTS WITH bisphenol A; C60 fullerene; copper atom.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HMGIC fusion partner-like protein 4; lipoma HMGIC fusion partner-like 4; lipoma HMGIC fusion partner-like protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84147,872,877 - 147,895,770 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4147,872,877 - 147,895,770 (-)EnsemblGRCr8
mRatBN7.24146,317,110 - 146,340,073 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,313,541 - 146,340,463 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4151,701,577 - 151,724,428 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04147,482,411 - 147,505,262 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,103,757 - 146,126,678 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,117,533 - 145,147,397 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,117,533 - 145,147,397 (-)Ensemblrn6Rnor6.0
Rnor_5.04208,415,890 - 208,445,642 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44149,049,668 - 149,072,608 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4134,877,048 - 134,898,925 (-)NCBICelera
RGSC_v3.14149,294,508 - 149,317,449 (-)NCBI
Cytogenetic Map4q42NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
dendrite  (IEA)
GABA-ergic synapse  (IEA,ISO)
inhibitory synapse  (IBA,IDA,IEA,ISO)
plasma membrane  (IBA)
postsynaptic membrane  (IBA,IEA,ISO,ISS)
postsynaptic specialization  (IEA,ISO)

Molecular Function
GABA receptor binding  (IBA,IDA,IEA,ISO)
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors. Davenport EC, etal., Cell Rep. 2017 Oct 3;21(1):70-83. doi: 10.1016/j.celrep.2017.09.025.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Yamasaki T, etal., Neuron. 2017 Mar 8;93(5):1138-1152.e6. doi: 10.1016/j.neuron.2017.02.023.
Additional References at PubMed
PMID:29742426  


Genomics

Comparative Map Data
Lhfpl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84147,872,877 - 147,895,770 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4147,872,877 - 147,895,770 (-)EnsemblGRCr8
mRatBN7.24146,317,110 - 146,340,073 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,313,541 - 146,340,463 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4151,701,577 - 151,724,428 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04147,482,411 - 147,505,262 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,103,757 - 146,126,678 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,117,533 - 145,147,397 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,117,533 - 145,147,397 (-)Ensemblrn6Rnor6.0
Rnor_5.04208,415,890 - 208,445,642 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44149,049,668 - 149,072,608 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4134,877,048 - 134,898,925 (-)NCBICelera
RGSC_v3.14149,294,508 - 149,317,449 (-)NCBI
Cytogenetic Map4q42NCBI
LHFPL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3839,498,361 - 9,553,822 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl39,498,361 - 9,553,823 (-)Ensemblhg38GRCh38
GRCh3739,540,045 - 9,595,506 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3639,515,045 - 9,570,486 (-)NCBIBuild 36Build 36hg18NCBI36
Celera39,474,743 - 9,530,187 (-)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef39,476,796 - 9,532,110 (-)NCBIHuRef
CHM1_139,490,268 - 9,545,714 (-)NCBICHM1_1
T2T-CHM13v2.039,490,279 - 9,545,747 (-)NCBIT2T-CHM13v2.0
Lhfpl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,145,048 - 113,172,345 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6113,145,051 - 113,172,345 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386113,168,087 - 113,195,384 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,168,090 - 113,195,384 (-)Ensemblmm10GRCm38
MGSCv376113,118,081 - 113,145,378 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366113,135,401 - 113,161,161 (-)NCBIMGSCv36mm8
Celera6114,996,909 - 115,024,142 (-)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.74NCBI
Lhfpl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555611,066,799 - 1,142,099 (-)Ensembl
ChiLan1.0NW_0049555611,066,799 - 1,142,099 (-)NCBIChiLan1.0ChiLan1.0
LHFPL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v229,510,331 - 9,565,838 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan139,515,093 - 9,570,591 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v039,453,628 - 9,506,434 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.139,695,091 - 9,745,722 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl39,695,091 - 9,745,722 (-)EnsemblpanPan2panpan1.1
LHFPL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1208,630,981 - 8,663,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl208,630,747 - 8,660,389 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha208,664,027 - 8,696,484 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0208,660,390 - 8,693,304 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl208,659,943 - 8,693,283 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1208,382,860 - 8,415,261 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0208,727,665 - 8,760,738 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0208,701,291 - 8,734,265 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lhfpl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494215,345,648 - 15,396,180 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366023,532,005 - 3,564,680 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366023,532,979 - 3,564,062 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LHFPL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1365,869,652 - 65,919,781 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11365,867,124 - 65,920,887 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21372,937,834 - 72,987,503 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LHFPL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12245,502,763 - 45,556,828 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041121,008,266 - 121,060,209 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lhfpl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247314,194,321 - 4,222,105 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247314,194,321 - 4,222,400 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lhfpl4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1633,330,339 - 33,355,313 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lhfpl4
209 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:92
Count of miRNA genes:83
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000010347
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4121020385148834277Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 4 27 126 50 49 22 18 22 6 124 66 106 24 57 27 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000010347   ⟹   ENSRNOP00000010347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4145,117,533 - 145,147,397 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111292   ⟹   ENSRNOP00000097018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,313,541 - 146,340,463 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114160   ⟹   ENSRNOP00000088962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,317,110 - 146,340,073 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000164144   ⟹   ENSRNOP00000110268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4147,872,877 - 147,895,770 (-)Ensembl
RefSeq Acc Id: NM_181387   ⟹   NP_852052
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84147,872,877 - 147,895,770 (-)NCBI
mRatBN7.24146,317,110 - 146,340,073 (-)NCBI
Protein Sequences
Protein RefSeqs NP_852052 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP37014 (Get FASTA)   NCBI Sequence Viewer  
  EDL91513 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000110268
GenBank Protein Q7TSY2 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000010347   ⟸   ENSRNOT00000010347
Ensembl Acc Id: ENSRNOP00000088962   ⟸   ENSRNOT00000114160
Ensembl Acc Id: ENSRNOP00000097018   ⟸   ENSRNOT00000111292
RefSeq Acc Id: NP_852052   ⟸   NM_181387
- UniProtKB: Q7TSY2 (UniProtKB/Swiss-Prot),   A6IBP5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000110268   ⟸   ENSRNOT00000164144

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TSY2-F1-model_v2 AlphaFold Q7TSY2 1-247 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727967 AgrOrtholog
BioCyc Gene G2FUF-43400 BioCyc
Ensembl Genes ENSRNOG00000007727 Ensembl
  ENSRNOG00000063676 Ensembl
  ENSRNOG00000091268 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000164144 ENTREZGENE
InterPro LHFPL UniProtKB/Swiss-Prot
KEGG Report rno:353230 UniProtKB/Swiss-Prot
NCBI Gene 353230 ENTREZGENE
PANTHER LHFPL TETRASPAN SUBFAMILY MEMBER 4 PROTEIN UniProtKB/Swiss-Prot
  PTHR12489 UniProtKB/Swiss-Prot
Pfam L_HMGIC_fpl UniProtKB/Swiss-Prot
PhenoGen Lhfpl4 PhenoGen
RatGTEx ENSRNOG00000007727 RatGTEx
  ENSRNOG00000063676 RatGTEx
  ENSRNOG00000091268 RatGTEx
UniProt A6IBP5 ENTREZGENE, UniProtKB/TrEMBL
  LHPL4_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Lhfpl4  LHFPL tetraspan subfamily member 4  Lhfpl4  LHFPL tetraspan subfamily member 4  Data merged from RGD:149736494 737654 PROVISIONAL
2021-08-09 Lhfpl4  LHFPL tetraspan subfamily member 4      Symbol and Name status set to provisional 45752 PROVISIONAL
2017-07-05 Lhfpl4  LHFPL tetraspan subfamily member 4  Lhfpl4  lipoma HMGIC fusion partner-like 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-11 Lhfpl4  lipoma HMGIC fusion partner-like 4  Lhfpl4  lipoma HMGIC fusion partner-like protein 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Lhfpl4  lipoma HMGIC fusion partner-like protein 4    HMGIC fusion partner-like protein 4  Name updated 1299863 APPROVED