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Gene: Wdr44 (WD repeat domain 44) Rattus norvegicus

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Symbol:

Wdr44

Name:

WD repeat domain 44

RGD ID:

727965

Description:

Enables small GTPase binding activity. Involved in regulation of cell migration. Located in microtubule and perinuclear region of cytoplasm. Orthologous to human WDR44 (WD repeat domain 44); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC246152; Rab11BP; rabphilin-11; WD repeat-containing protein 44; WD-containing protein Rab11BP/Rabphilin-11

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	WDR44 (WD repeat domain 44)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Wdr44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Wdr44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	WDR44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	WDR44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Wdr44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	WDR44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	WDR44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Wdr44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Wdr44 (WD repeat domain 44)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	WDR44 (WD repeat domain 44)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Wdr44 (WD repeat domain 44)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	wdr44 (WD repeat domain 44)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DGR2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG34133	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	sym-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YMR102C	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	wdr44	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	wdr44	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	119,286,802 - 119,392,240 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	119,287,142 - 119,392,232 (+)	Ensembl				GRCr8
mRatBN7.2	X	114,481,890 - 114,587,307 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	114,482,006 - 114,587,224 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	116,513,860 - 116,619,396 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	120,005,121 - 120,110,659 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	117,558,726 - 117,664,256 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	120,860,178 - 120,965,918 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	120,859,968 - 120,965,910 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	121,006,674 - 121,111,932 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	9,720,140 - 9,825,685 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	113,672,342 - 113,777,724 (+)	NCBI		Celera
RGSC_v3.1	X	9,726,056 - 9,830,906 (-)	NCBI
Cytogenetic Map	X	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,6-dimethoxyphenol (ISO)

2,6-dinitrotoluene (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

bortezomib (ISO)

Bufotalin (ISO)

caffeine (ISO)

CGP 52608 (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

dimethyl sulfoxide (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

furfural (ISO)

ivermectin (ISO)

methotrexate (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

potassium chromate (ISO)

quercetin (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium chloride (ISO)

sulforaphane (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytosolic ciliogenesis (IBA,IEA,ISO,ISS)

negative regulation of cilium assembly (IEA,ISO,ISS)

regulation of cell migration (IMP)

regulation of vesicle-mediated transport (IBA,IEA,ISO,ISS)

Cellular Component

cytosol (IEA)

endosome membrane (IBA,IEA,ISO)

Golgi apparatus (IBA,IEA,ISO)

microtubule (IDA)

perinuclear region of cytoplasm (IDA,IEA)

Molecular Function

molecular sequestering activity (IBA,IEA,ISO,ISS)

protein binding (ISO)

small GTPase binding (IDA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rab11BP/Rabphilin-11, a downstream target of rab11 small G protein implicated in vesicle recycling.	Mammoto A, etal., J Biol Chem 1999 Sep 3;274(36):25517-24.
3.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Wdr44
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	119,286,802 - 119,392,240 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	119,287,142 - 119,392,232 (+)	Ensembl				GRCr8
mRatBN7.2	X	114,481,890 - 114,587,307 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	114,482,006 - 114,587,224 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	116,513,860 - 116,619,396 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	120,005,121 - 120,110,659 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	117,558,726 - 117,664,256 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	120,860,178 - 120,965,918 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	120,859,968 - 120,965,910 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	121,006,674 - 121,111,932 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	9,720,140 - 9,825,685 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	113,672,342 - 113,777,724 (+)	NCBI		Celera
RGSC_v3.1	X	9,726,056 - 9,830,906 (-)	NCBI
Cytogenetic Map	X	q34	NCBI

WDR44
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	118,346,073 - 118,449,961 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	118,345,968 - 118,450,285 (+)	Ensembl			hg38	GRCh38
GRCh37	X	117,480,036 - 117,583,924 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	117,364,070 - 117,467,952 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	117,261,923 - 117,365,803	NCBI
Celera	X	117,934,854 - 118,038,746 (+)	NCBI		Celera
Cytogenetic Map	X	q24	NCBI
HuRef	X	106,974,656 - 107,079,039 (+)	NCBI		HuRef
CHM1_1	X	117,390,888 - 117,494,837 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	116,723,730 - 116,827,622 (+)	NCBI		T2T-CHM13v2.0

Wdr44
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	23,559,231 - 23,672,265 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	23,559,290 - 23,672,264 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	23,692,402 - 23,806,026 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	23,693,051 - 23,806,025 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	23,270,243 - 23,383,128 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	22,850,010 - 22,962,984 (+)	NCBI		MGSCv36	mm8
Celera	X	21,785,140 - 21,898,540 (+)	NCBI		Celera
Cytogenetic Map	X	A2	NCBI
cM Map	X	17.36	NCBI

Wdr44
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955534	1,490,830 - 1,599,408 (-)	Ensembl
ChiLan1.0	NW_004955534	1,492,990 - 1,599,402 (-)	NCBI	ChiLan1.0	ChiLan1.0

WDR44
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	117,703,876 - 117,810,663 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	117,707,484 - 117,814,963 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	107,353,013 - 107,456,986 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	117,804,737 - 117,907,764 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	117,805,236 - 117,907,764 (+)	Ensembl			panPan2	panpan1.1

WDR44
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	90,571,138 - 90,653,094 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	90,571,554 - 90,652,647 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	76,712,119 - 76,761,098 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	92,311,013 - 92,393,276 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	92,310,889 - 92,393,270 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	89,765,063 - 89,846,425 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	91,516,928 - 91,598,257 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	91,251,305 - 91,333,551 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Wdr44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	89,521,967 - 89,613,716 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936479	11,373,717 - 11,465,607 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936479	11,373,781 - 11,465,516 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WDR44
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	96,950,288 - 97,027,050 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	96,950,288 - 97,027,069 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

WDR44
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666065	31,070,326 - 31,167,781 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wdr44
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624895	2,323,426 - 2,414,711 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624895	2,323,407 - 2,414,324 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Wdr44
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	51,124,905 - 51,227,056 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Wdr44
604 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	12
Count of miRNA genes:	12
Interacting mature miRNAs:	12
Transcripts:	ENSRNOT00000040742
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	97528096	142528096	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	105359969	157758123	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	80434318	125434318	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	105468858	125434318	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	118973754	157758123	Rat
2302047	Pia34	Pristane induced arthritis QTL 34	5.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	19	96916163	141916163	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF130121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000040742 ⟹ ENSRNOP00000047275

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	119,327,946 - 119,389,134 (+)	Ensembl
mRatBN7.2 Ensembl	X	114,523,015 - 114,584,201 (+)	Ensembl
Rnor_6.0 Ensembl	X	120,901,495 - 120,965,559 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085185 ⟹ ENSRNOP00000070165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	114,482,006 - 114,586,290 (+)	Ensembl
Rnor_6.0 Ensembl	X	120,859,968 - 120,953,086 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000088661 ⟹ ENSRNOP00000074327

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	119,287,142 - 119,392,232 (+)	Ensembl
mRatBN7.2 Ensembl	X	114,482,071 - 114,587,224 (+)	Ensembl
Rnor_6.0 Ensembl	X	120,860,178 - 120,965,910 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099992 ⟹ ENSRNOP00000091147

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	119,327,114 - 119,389,013 (+)	Ensembl
mRatBN7.2 Ensembl	X	114,522,183 - 114,583,987 (+)	Ensembl

RefSeq Acc Id:

NM_001100823 ⟹ NP_001094293

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	119,287,142 - 119,392,240 (+)	NCBI
mRatBN7.2	X	114,482,207 - 114,587,307 (+)	NCBI
Rnor_6.0	X	120,860,178 - 120,965,918 (+)	NCBI
Rnor_5.0	X	121,006,674 - 121,111,932 (+)	NCBI
Celera	X	113,672,342 - 113,777,724 (+)	NCBI

Sequence:

show sequence

CCACCTCGGGCAGTCGCTTTGCAGGTCATACCCTTAGCCCAGCAACTGAGGGTGGTCCCCTGTC
CCTAACCGACTTCTCACTCCACGTCATCTGTGCCCTCTTCAGAGTCGCCTGGGACCCACCTCTC
TACACTCTTAACTGACGAGGAGGAGACGCTCGGAATCACCCTTTCTCTAGGCGGAGCCGGCCCC
CTCACCCGCGGGTGTGTCCTATAAATGGCGTCGGAAAGCGACACTGAGGAATTCTATGATGCCC
CTGAAGATGTGCACCTGGGGGGCAGCTATCCTGTGGGGTCTCCAGGAAAAGTTGGACTTTTATC
ATTCAAGGAAACAAAGAATACAGGAAACAAAGCTGGAAATGAGTCCCCTGTACAAGAATTGAGA
CAAGATGTATCTAAAAAGATAATTGAATGTATTATTGAGGAAAGTCAGAAAGTACTACAATTGG
AAGATGACTCTTTGGATTCCAAAGGAAAAGGACTTTCTGATCAGGCCACTGCTAGTCATTCTGT
GGCTGGGACAGAGTTTAGTAACATACCTGGACTATTAGCCATACAGCATGAACTACAACAAGGT
TCCAGAAAGGCAGACAGTCAGAATGCAGCTGAAGAAACTGAACTAGAAACACAAAAATGTTTTC
CTTCTGATAACAACTGTGAGAAGAGTGAGAAGACAGAAGATGAAACTAATAATTTAACTGAAGT
AAGTTCAGCTGATCAGCTTGATGCTTCTAAACTAGAAACTGAAATATTGAACAAGGAAGCAGTG
GAAGTCAAAGAAGGTGATGTTGTAAATCCTGCATCCTCAGATGCTCTATCTACTAAAGATTTTG
CTGCTGTGGAAGAAGTGGCTCCCGCCAAACCCCCAAGGCACCTTACTCCAGAACCTGATATAGT
AGCCAGTACAAAGAAGCCTGTTCCTGCACGCCCACCCCCACCAACTAATTTCCCACCTCCTAGA
CCGCCACCTCCATCTCGACCTGCACCACCACCAAGAAAAAAGAAAAGTGACCTGGAGTTTGAGG
CTCTTAAAACACCTGATCTGGATGTACCCAAAGACAATATTGCATCTGATTCTCTGCTAACTAC
AAATATGGCTTCAGAAAGTACAGTTAGAGATTCTCTGCCTTCTCTCGATTTAGCAAGTGCTACC
AGTGGAGATAAAATAGTTACTGCCCAGGAAAATGGAAAAGCACCTGATGTGCAGACAGTAGCAG
GTGAAGTGATGGGCCCTCAGAGACCTAGATCCAACTCTGGAAGAGAGCTTACTGATGAGGAAAT
TTTAGCCAGTGTAATGATTAAGAACCTGGATACTGGAGAAGAAATACCTTTAAGTCTTGCTGAA
GAGAAGTTGCCCACAGGTATTAATCCTCTCACCCTGCACATCATGAGGAGGACAAAGGAGTATG
TAAGCAATGATGCCACACAGTCAGATGATGAAGAAAAGTTACAGTCACAACAAACAGATACTGA
CGGTGGAAGGTTAAAACAGAAAACGACTCAACTAAAGAAATTCCTTGGAAAATCAGTAAAGAGA
GCAAAGCATCTTGCTGAGGAATATGGTGAACGTGCTATAAATAAAGTTAAAAGTGTAAGAGATG
AAGTGTTTCATACTGATCAAGATGACCCTTCATCAAGTGATGATGAAGGAATGCCATATACAAG
ACCAGTAAAATTCAAGGCAGCGCATGGTTTCAAAGGACCTTATGATTTTGATCAGATCAAAGTG
GTACAAGATCTTAGTGGTGAACACATGGGAGCTGTTTGGACCATGAAATTTTCTCACTGTGGCC
GGTTACTTGCCTCAGCTGGACAAGACAATATAGTGAGAATATGGGCTTTAAAAAATGCTTTTGA
CTATTTCAACAATATGCGAATGAAATACAATACTGAAGGACGTGTGTCACCTTCACCATCTCAG
GAAAGTCTAAGTTCATCAAAATCAGATACAGACATGGGGGTATGTAGTGGAACTGACGAAGACC
CAGATGACAAAAATGCACCTTTTCGGCAACGACCATTTTGCAAATATAAGGGACATACTGCTGA
TCTCCTTGATCTTTCGTGGTCTAAAAACTACTTTCTGCTCTCTTCTTCTATGGATAAAACTGTC
AGGTTATGGCACATTTCTAGAAGAGAATGCCTTTGCTGTTTTCAACACATAGATTTTGTCACTG
CCATCGCTTTCCATCCAAGAGATGACAGATATTTTCTCAGTGGATCATTGGATGGAAAGCTCCG
CCTATGGAACATACCTGACAAAAAAGTGGCTTTATGGAATGAAGTAGATGGTCAGACAAAGTTG
ATCACAGCTGCCAATTTTTGTCAGAACGGCAAATATGCAGTAATTGGGACATATGATGGTAGAT
GTATTTTCTATGATACAGAGCACTTGAAATACCATACACAAATACATGTACGATCTACTAGAGG
GCGGAACAAGGTTGGAAGAAAAATTACTGGGATTGAACCTTTACCTGGGGAAAATAAGATATTG
GTAACCTCAAATGACTCCAGAATCAGACTGTATGATCTGAGAGACCTATCACTGTCCATGAAGT
ATAAGGGTTATGTCAATAGCAGCAGCCAGATCAAAGCAAGTTTCAGCCATGACTTTACTTACCT
CGTTAGCGGTTCAGAAGATAAATATGTTTATATCTGGAGTACTTACCATGACCTAAGCAAGTTT
ACTTCAGTCAGGAGAGATCGTAATGACTTCTGGGAAGGTATTAAAGCACATAATGCAGTTGTTA
CGTCAGCCATCTTTGCTCCAAACCCAAGTTTGATGCTATCCTTGGATGTGCAGTCTGAAAAATT
GGAAGGGATTGATAAATATGAAGATGCTGAAGTTTTGGATAACACATCTACTGGTATCGTGAAG
ACAGATAACACAGAAGTTCTTCTCTCTGCTGATTTTACTGGAGCAATCAAAGTGTTTATTAACA
AAAGGAAAACTGTATCTTAATTTGAAATTATATTTAAAATAAACATATCACTAAGTTTCTATAT
GTATCAGAAATGAGAAAAATATTATAGTGTTTAAGGCTAACATCCTTTTTTAGCTTTTATTGAA
AGTTGTTCAAATATAATATATATTTTTTGAGAGGCAGTGTTAGTGATCTAGGAACTCCTAGACT
GATAGACTAGAAAAGAATGTGGCTAGATTAACATTGCCAAGCATAGAGTTTATGTTTTATTATG
TTGATGTTTTGTTATATAATTATAAACATGCACAGGTTTCTGCATGAAAAGATATTAATATATT
AATCACATGTGCGTGCCTTTTGGTTACATGCACTAAATCTAACAAAGTTAAATTATTTTGGTGG
CTCTTTTGGCCTCCTACTAGGTGAGGTGGTCTTGTTTTTAGTTCTAAAAAGTTTCTTTGCACAA
AATTTCGTTTTTAAGAAATGTATCTTTTGACTGAATTATTGTTTTGAAAATGTTATATAGGTTT
TCAATAGGTCAATAACCATATGTAAATGGTTTTTTATAAATTTCTCAATTTGGGGACAATATTT
TTTTGTGATCTAAATTGTGGACTTATTCTTTACTTTGTAAGTGTATATATATATATGTATATAT
ATATATAAATATAATTTTTTCTTTGCAACACTGGAGCACAATGTTTCTATGTAAAGAATTCTTT
TCTTTATCCATGAGCACCAGGCTTTGCTCACTTAAAAATAAGCCACATTAAGGAGTGAGTCTTC
TTTTTTTACAATAATGTAAAAATGAACTGTTTACATTTTTTTAAAGCATTGTAGTTTTTAAAAA
TTAAGCTGTTTTGTTTTGTGTTGTTGAATTTGAAAGGCTTTGTAAATATCAATATAATGTACCA
ATGAAATAACATCTGGGACAATGGAACCCTGGTAATGTTGTTGATGGTTTGCATATGTTTCTGA
AACTGAAATATGTATCATTAAAGTTGGTCATCAACACTTGTTAAAGGTGAGTTATTTTCAGATG
ACTTTAGTAAATCAAGAGATGCAAGAAAAATAAATTATTGTCTTAAAAAGAC

hide sequence

RefSeq Acc Id:

XM_039099449 ⟹ XP_038955377

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	119,286,802 - 119,392,163 (+)	NCBI
mRatBN7.2	X	114,482,015 - 114,587,306 (+)	NCBI

RefSeq Acc Id:

XM_039099450 ⟹ XP_038955378

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	119,286,802 - 119,392,163 (+)	NCBI
mRatBN7.2	X	114,481,890 - 114,587,306 (+)	NCBI

RefSeq Acc Id:

XM_063279776 ⟹ XP_063135846

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	119,286,802 - 119,392,163 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001094293	(Get FASTA)	NCBI Sequence Viewer
	XP_038955377	(Get FASTA)	NCBI Sequence Viewer
	XP_038955378	(Get FASTA)	NCBI Sequence Viewer
	XP_063135846	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF02478	(Get FASTA)	NCBI Sequence Viewer
	EDM10796	(Get FASTA)	NCBI Sequence Viewer
	EDM10797	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000047275
	ENSRNOP00000074327
GenBank Protein	Q9R037	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001094293 ⟸ NM_001100823

- UniProtKB:

A0A0G2JX77 (UniProtKB/TrEMBL), A6JMD4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASESDTEEFYDAPEDVHLGGSYPVGSPGKVGLLSFKETKNTGNKAGNESPVQELRQDVSKKII
ECIIEESQKVLQLEDDSLDSKGKGLSDQATASHSVAGTEFSNIPGLLAIQHELQQGSRKADSQN
AAEETELETQKCFPSDNNCEKSEKTEDETNNLTEVSSADQLDASKLETEILNKEAVEVKEGDVV
NPASSDALSTKDFAAVEEVAPAKPPRHLTPEPDIVASTKKPVPARPPPPTNFPPPRPPPPSRPA
PPPRKKKSDLEFEALKTPDLDVPKDNIASDSLLTTNMASESTVRDSLPSLDLASATSGDKIVTA
QENGKAPDVQTVAGEVMGPQRPRSNSGRELTDEEILASVMIKNLDTGEEIPLSLAEEKLPTGIN
PLTLHIMRRTKEYVSNDATQSDDEEKLQSQQTDTDGGRLKQKTTQLKKFLGKSVKRAKHLAEEY
GERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEH
MGAVWTMKFSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKS
DTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRR
ECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQ
NGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRI
RLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRN
DFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKLEGIDKYEDAEVLDNTSTGIVKTDNTEVLL
SADFTGAIKVFINKRKTVS

hide sequence

Ensembl Acc Id:

ENSRNOP00000070165 ⟸ ENSRNOT00000085185

Ensembl Acc Id:

ENSRNOP00000074327 ⟸ ENSRNOT00000088661

Ensembl Acc Id:

ENSRNOP00000047275 ⟸ ENSRNOT00000040742

RefSeq Acc Id:	XP_038955378 ⟸ XM_039099450
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K7S6 (UniProtKB/TrEMBL), A6JMD4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038955377 ⟸ XM_039099449
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K7S6 (UniProtKB/TrEMBL), A6JMD4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000091147 ⟸ ENSRNOT00000099992

RefSeq Acc Id:	XP_063135846 ⟸ XM_063279776
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2JX77 (UniProtKB/TrEMBL), A6JMD4 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9R037-F1-model_v2	AlphaFold	Q9R037	1-908	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701980

Promoter ID:

EPDNEW_R12499

Type:

initiation region

Name:

Wdr44_1

Description:

WD repeat domain 44

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	120,860,028 - 120,860,088	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727965	AgrOrtholog
BioCyc Gene	G2FUF-1342	BioCyc
Ensembl Genes	ENSRNOG00000029068	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000040742	ENTREZGENE
	ENSRNOT00000088661	ENTREZGENE
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot
InterPro	G-protein_beta_WD-40_rep	UniProtKB/Swiss-Prot
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot
	WD40_repeat	UniProtKB/Swiss-Prot
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot
	WDR44/Dgr2	UniProtKB/Swiss-Prot
NCBI Gene	246152	ENTREZGENE
PANTHER	PTHR14221	UniProtKB/Swiss-Prot
	WD REPEAT-CONTAINING PROTEIN 44	UniProtKB/Swiss-Prot
Pfam	WD40	UniProtKB/Swiss-Prot
PhenoGen	Wdr44	PhenoGen
PRINTS	GPROTEINBRPT	UniProtKB/Swiss-Prot
PROSITE	WD_REPEATS_2	UniProtKB/Swiss-Prot
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000029068	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot
UniProt	A0A0G2JX77	ENTREZGENE
	A0A0G2K7S6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AB16_RAT	UniProtKB/TrEMBL
	A6JMD4	ENTREZGENE, UniProtKB/TrEMBL
	A6JMD5_RAT	UniProtKB/TrEMBL
	F1LSM3_RAT	UniProtKB/TrEMBL
	Q9R037	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-08	Wdr44	WD repeat domain 44	LOC246152	WD-containing protein Rab11BP/Rabphilin-11	Symbol and Name updated	1299863	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_mutations_overexpression	overexpression of C-terminal fragment (lacking the GTP-Rab11 binding domain) reduced accumulation of transferrin in perinuclear regions and cell migration	1299615

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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