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Gene: Spaca9 (sperm acrosome associated 9) Rattus norvegicus

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Symbol:

Spaca9

Name:

sperm acrosome associated 9

RGD ID:

727909

Description:

Predicted to enable calcium-dependent protein binding activity and microtubule binding activity. Predicted to be involved in axoneme assembly and flagellated sperm motility. Located in cytoplasm and nucleus. Orthologous to human SPACA9 (sperm acrosome associated 9); INTERACTS WITH 1,3-dinitrobenzene; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MGC114240; Rsb-66 protein; Rsb66; sperm acrosome-associated protein 9; uncharacterized protein C9orf9 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SPACA9 (sperm acrosome associated 9)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Spaca9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Spaca9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SPACA9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SPACA9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Spaca9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SPACA9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SPACA9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Spaca9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Spaca9 (sperm acrosome associated 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	H1-5 (H1.5 linker histone, cluster member)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SPACA9 (sperm acrosome associated 9)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Spaca9 (sperm acrosome associated 9)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	spaca9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	spaca9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	spaca9	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	32,417,350 - 32,426,776 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	32,417,350 - 32,426,934 (-)	Ensembl				GRCr8
mRatBN7.2	3	12,019,376 - 12,028,801 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	12,019,363 - 12,029,119 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	15,091,781 - 15,100,694 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	23,676,739 - 23,685,652 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	21,931,188 - 21,940,109 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	7,269,851 - 7,279,253 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	7,269,853 - 7,278,758 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	12,620,541 - 12,630,046 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	7,677,850 - 7,686,755 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	6,800,098 - 6,809,003 (-)	NCBI		Celera
RGSC_v3.1	3	7,678,149 - 7,687,055 (-)	NCBI
Cytogenetic Map	3	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Ehlers-Danlos syndrome classic type 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,3-dinitrobenzene (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cocaine (EXP)

Cuprizon (EXP)

D-glucose (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

formaldehyde (ISO)

fructose (ISO)

glucose (ISO)

glycidol (EXP)

glyphosate (EXP,ISO)

methamphetamine (EXP)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

ochratoxin A (EXP)

okadaic acid (ISO)

rotenone (ISO)

SCH 23390 (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

thapsigargin (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axoneme assembly (IEA,ISO)

flagellated sperm motility (ISO)

Cellular Component

acrosomal vesicle (IBA,IEA,ISO)

axonemal microtubule (IEA,ISO,ISS)

axonemal microtubule doublet inner sheath (ISO,ISS)

axoneme (IEA,ISO)

ciliary basal body (ISO,ISS)

ciliary base (IBA,ISO)

cytoplasm (IDA,IEA,ISO)

cytoplasmic microtubule (IEA,ISO)

cytoplasmic vesicle (IEA)

cytosol (IEA,ISO)

nucleus (IDA,IEA)

sperm end piece (IEA,ISO)

sperm flagellum (IBA,ISO)

Molecular Function

calcium-dependent protein binding (ISO)

microtubule binding (IEA,ISO,ISS)

protein binding (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	A novel testis protein, RSB-66, interacting with INCA1 (inhibitor of Cdk interacting with cyclin A1).	Chen X, etal., Biochem Cell Biol. 2008 Aug;86(4):345-51.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:23264731	PMID:24256100	PMID:27914912	PMID:31904090

Genomics

Comparative Map Data

Spaca9
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	32,417,350 - 32,426,776 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	32,417,350 - 32,426,934 (-)	Ensembl				GRCr8
mRatBN7.2	3	12,019,376 - 12,028,801 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	12,019,363 - 12,029,119 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	15,091,781 - 15,100,694 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	23,676,739 - 23,685,652 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	21,931,188 - 21,940,109 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	7,269,851 - 7,279,253 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	7,269,853 - 7,278,758 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	12,620,541 - 12,630,046 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	7,677,850 - 7,686,755 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	6,800,098 - 6,809,003 (-)	NCBI		Celera
RGSC_v3.1	3	7,678,149 - 7,687,055 (-)	NCBI
Cytogenetic Map	3	p12	NCBI

SPACA9
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	132,878,344 - 132,890,314 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	132,878,027 - 132,890,201 (+)	Ensembl			hg38	GRCh38
GRCh37	9	135,753,731 - 135,765,588 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	134,744,111 - 134,755,239 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	132,783,843 - 132,794,972	NCBI
Celera	9	106,296,025 - 106,307,156 (+)	NCBI		Celera
Cytogenetic Map	9	q34.13	NCBI
HuRef	9	105,248,210 - 105,259,341 (+)	NCBI		HuRef
CHM1_1	9	135,904,767 - 135,915,896 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	145,090,157 - 145,104,158 (+)	NCBI		T2T-CHM13v2.0

Spaca9
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	28,582,092 - 28,589,663 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	28,582,092 - 28,589,739 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	28,692,080 - 28,699,651 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	28,692,080 - 28,699,727 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	28,547,600 - 28,555,171 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	28,514,089 - 28,521,660 (-)	NCBI		MGSCv36	mm8
Celera	2	28,396,586 - 28,404,157 (-)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	19.38	NCBI

Spaca9
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	2,185,754 - 2,196,323 (+)	Ensembl
ChiLan1.0	NW_004955513	2,184,878 - 2,196,367 (+)	NCBI	ChiLan1.0	ChiLan1.0

SPACA9
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	6,469,929 - 6,481,751 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	6,472,265 - 6,484,079 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	103,994,592 - 104,006,390 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	132,624,823 - 132,636,687 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	132,625,393 - 132,636,686 (+)	Ensembl			panPan2	panpan1.1

SPACA9
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	51,460,359 - 51,470,612 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	51,460,623 - 51,468,902 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	50,725,624 - 50,735,580 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	52,355,800 - 52,365,756 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	52,355,801 - 52,364,080 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	51,134,188 - 51,144,133 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	51,458,670 - 51,468,614 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	51,538,193 - 51,548,137 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Spaca9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	199,553,674 - 199,561,717 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	19,322,201 - 19,330,245 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	19,322,207 - 19,331,434 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SPACA9
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	272,625,712 - 272,636,346 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	272,625,701 - 272,635,406 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	306,779,769 - 306,792,021 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SPACA9
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	5,250,367 - 5,263,194 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	5,250,063 - 5,263,186 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666079	10,382,593 - 10,395,466 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Spaca9
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	3,537,550 - 3,545,456 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624760	3,537,547 - 3,546,027 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Spaca9
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	7,974,117 - 7,983,819 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Spaca9
71 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	68
Count of miRNA genes:	61
Interacting mature miRNAs:	65
Transcripts:	ENSRNOT00000017004
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	29056275	47904329	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10450811	Scl73	Serum cholesterol level QTL 73	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat
10450808	Scl72	Serum cholesterol level QTL 72	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
10450806	Scl71	Serum cholesterol level QTL 71	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	28625339	67641995	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	6125437	51125437	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	30832384	44921701	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	36721849	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	6556347	51556347	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	15272348	60272348	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	29056275	47904329	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	10	37	132	78	77	47	65	47	6	244	122	1	113	56	85	30	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001401818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_181694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283482	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY121839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017004 ⟹ ENSRNOP00000017004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	32,417,350 - 32,426,934 (-)	Ensembl
mRatBN7.2 Ensembl	3	12,019,378 - 12,029,119 (-)	Ensembl
Rnor_6.0 Ensembl	3	7,269,853 - 7,278,758 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112266 ⟹ ENSRNOP00000095426

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	32,417,926 - 32,426,934 (-)	Ensembl
mRatBN7.2 Ensembl	3	12,019,376 - 12,029,119 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120222 ⟹ ENSRNOP00000088937

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	32,417,926 - 32,426,277 (-)	Ensembl
mRatBN7.2 Ensembl	3	12,019,363 - 12,028,283 (-)	Ensembl

RefSeq Acc Id:

NM_001401818 ⟹ NP_001388747

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	32,417,926 - 32,426,277 (-)	NCBI
mRatBN7.2	3	12,019,952 - 12,028,303 (-)	NCBI

RefSeq Acc Id:

NM_181694 ⟹ NP_859045

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	32,417,350 - 32,426,277 (-)	NCBI
mRatBN7.2	3	12,019,376 - 12,028,303 (-)	NCBI
Rnor_6.0	3	7,269,853 - 7,278,758 (-)	NCBI
Rnor_5.0	3	12,620,541 - 12,630,046 (-)	NCBI
RGSC_v3.4	3	7,677,850 - 7,686,755 (-)	RGD
Celera	3	6,800,098 - 6,809,003 (-)	RGD

Sequence:

show sequence

CAAGCTTCTGGGCAGTCTGTGAGGCGAAGGCCAGTCCAAGTCAAACCAGGACCCTTCCTGTCCT
GTGGGACCTAACAGCAACAATGAATGAGGTGAAAGAGTCCCTCCGCAGCATCGAGCAGAAGTAC
AAACTCTTTCAGCAGCAACAGTTCACCTTCATTGCTGCTCTGGAGCACTGCCGGGAGAATGCCC
ACGACAAAATCCGGCCCATCTCCAGTATCGAGCAGGTGCAGAGCTACATGGAACATTACTGCAA
TAACTCCACCGACCGGCGGATTCTGCTCATGTTCATGGACATCTGCTCGGAGCTCAACAAACTG
TGCCAGCACTTTGAGGCCTTGCACTCCGGCACCCCTGTCACCAACAGCCTTCTCGAGAAATGCA
AAACCCTGGTTAGCCAGAGCAATGACTTGAGCATCCTCAGAGCAAAGTACCCGCATGATGTGGT
GAACCACCTCAGCTGTGATGAGGCCAGGAACCACTATGGAGGTGTGGTCAGCCTCATCCCCATA
GTCCTGGACCTAATGAAAGAGTGGATCGCTCATTCCGAGAAGCTGCCTCGCAAAGTGCTGCAGC
ATGGGACGACTTAGCTTCTGTACTGTTGCTTCCTCGGGGGGAGACATTCAAGAATAAAATGTTC
TGCCACTTCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006233766 ⟹ XP_006233828

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	32,417,350 - 32,426,776 (-)	NCBI
mRatBN7.2	3	12,019,376 - 12,028,801 (-)	NCBI
Rnor_6.0	3	7,269,851 - 7,279,253 (-)	NCBI
Rnor_5.0	3	12,620,541 - 12,630,046 (-)	NCBI

Sequence:

show sequence

TGTGGGACCACTGCGCAATGGCTCTAGGACGCCGGGAGAGGGCACAGAGCAGAGATTCAAAGAC
GTCCCGAGGAGCCGCCCTGTGTGAACGTCTCCAGGGGGGCGAGGAGACCCTTCCTGTCCTGTGG
GACCTAACAGCAACAATGAATGAGGTGAAAGAGTCCCTCCGCAGCATCGAGCAGAAGTACAAAC
TCTTTCAGCAGCAACAGTTCACCTTCATTGCTGCTCTGGAGCACTGCCGGGAGAATGCCCACGA
CAAAATCCGGCCCATCTCCAGTATCGAGCAGGTGCAGAGCTACATGGAACATTACTGCAATAAC
TCCACCGACCGGCGGATTCTGCTCATGTTCATGGACATCTGCTCGGAGCTCAACAAACTGTGCC
AGCACTTTGAGGCCTTGCACTCCGGCACCCCTGTCACCAACAGCCTTCTCGAGAAATGCAAAAC
CCTGGTTAGCCAGAGCAATGACTTGAGCATCCTCAGAGCAAAGTACCCGCATGATGTGGTGAAC
CACCTCAGCTGTGATGAGGCCAGGAACCACTATGGAGGTGTGGTCAGCCTCATCCCCATAGTCC
TGGACCTAATGAAAGAGTGGATCGCTCATTCCGAGAAGCTGCCTCGCAAAGTGCTGCAGCATGG
GACGACTTAGCTTCTGTACTGTTGCTTCCTCGGGGGGAGACATTCAAGAATAAAATGTTCTGCC
ACTTCTC

hide sequence

RefSeq Acc Id:

XM_017591644 ⟹ XP_017447133

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	32,417,350 - 32,424,741 (-)	NCBI
mRatBN7.2	3	12,019,952 - 12,026,733 (-)	NCBI
Rnor_6.0	3	7,270,427 - 7,278,682 (-)	NCBI

Sequence:

show sequence

GAACTGGGTGGAAAACACTAGGGGAGTCAGGGAGAAAGAGGTGGCGGTTTCCTGACCTAGAGGG
AGGAGAGCTGCACGTTGCTGTGGAAGGGACAAGGGTGGCAGGCAGCGTGGAGAAGGCATTGTGT
ACTAACCCAGAGGGAGGTGCGCACAACCTACAGGGACAGCCACAGCCCAACTTGTGTCTAGATG
TTGTGAGTTTGACAAATTTGCCGTGGGCGGGCCTAGTTTCTACCCTGAGCAATGGGGAACAACT
TAAACATTCCTCCCACGACTAACCTAAGTAACTGGCCTATAGGAAGTGGACAGTGTGGGCACAT
AGTGATAAATCTCACTTAACTGTTAGACTGATCTTACTTAACCTCACCTCAGTCACTTTAGACA
ACAGGAGCTCCTGTCTCACAAGTTTTATTTTTATTTATTTATGTGTATACCGGTGGGACAGAGG
AAGAGCCGAGGCTGGAAAGGGAGTTTGGAACCCTGAAGCTGGAGTTGCGGGCAGCGAGCCGATA
TAGATCTAGTGCTGAGAACTAAACCCAGGTCTTCTGGGAGCGCAGCAAGTGCTCAGAGCTGAGT
CACTGCAGCCCCTACAGTTTGTTTACATGGGCCAAGTACCAAGTTGGGCTTTCAGGAGCTCCTG
GGGCCATAGCACCAGGCAGTGTCAGTCCAATGAAAACCTTTCTACTCGGAATACAGACAAGACA
CGGCAGATTAAGACAGGCCAGAGGAGTTAGCTGGGTGACTTTGGGCAAGTCATTTCCCCTTTCT
GGATCTCTTTCCTCACCAGCGCTGGGCAGAGAGGAAGCTTTCAAGAGTGTGAAGAGTTTCCATC
CAAACTCCCTCCTTTTATAAAAAACAGAGACTGAGGCCTAGCAAAGGGGAAAAGCCTTGCCCAG
GGGCTGAGAATGAAATCAGAGGGAGCCTCAAGGCTAGAAGCTGGAGTCCTGACCTGGGATTATG
ACACCTGCCCATATAAAGCCGGCAGCGTGCAGCCCTGCATCCCCATGACCTGCTTCCTCAGAGG
CCTCAGGCCTTGGTAGACTTGTCAGCTGGGGAAGCAAAGATAAGGCCTCCTCAACAAAGAAGCC
TGCAGCTTGCACTGGGGGGTTCATGTGCTTCCTGGACATTTTTGAAGTGGCTTTCGTCTCTCCT
CATTTATTTTAAGCCCTAGGCGCTTTTCATACCATGATCTAATCTTCTTGAGCAGCCTGGAAAA
ATACAAATCAATTAAAGCCTCAAACCTATGGGGTAATCACCTTTCCCTGCCTTCTCCCCCCAGA
GAGAACGGAGCTTGCTTCTGGGTCTTTCATCTACTCTAATTTGGCTGCAGAGGCCTGTGGTCAG
GGGCCAATCACTTTGGATAGCTAGTTACATCCCCTTTTGTGACATCCCTGACATGTTCATGTCA
CAAGTTGCTAGGATCAAGAACTGAGTCAGGTTTGCTCTAGGGAGCTCATGGGGCGCAGCAAGCC
AGTTAGCACGGCTTCCTTGGAGAACCTGGGAGCCCAGAGGATGGGCTGAGCCCACTGCAGTGAA
CCCTGTGAATGCTACTTCTCATTGCTCTGGGATAGGAGTGGAAGTGAGGTCCCGAGCCCAGCTA
GTGGAGGACCCCAGAAGTGGCTGGACCCTTCCTGTCCTGTGGGACCTAACAGCAACAATGAATG
AGGTGAAAGAGTCCCTCCGCAGCATCGAGCAGAAGTACAAACTCTTTCAGCAGCAACAGTTCAC
CTTCATTGCTGCTCTGGAGCACTGCCGGGAGAATGCCCACGACAAAATCCGGCCCATCTCCAGT
ATCGAGCAGGTGCAGAGCTACATGGAACATTACTGCAATAACTCCACCGACCGGCGGATTCTGC
TCATGTTCATGGACATCTGCTCGGAGCTCAACAAACTGTGCCAGCACTTTGAGGCCTTGCACTC
CGGCACCCCTGTCACCAACAGCCTTCTCGAGAAATGCAAAACCCTGGTTAGCCAGAGCAATGAC
TTGAGCATCCTCAGAGCAAAGTACCCGCATGATGTGGTGAACCACCTCAGCTGTGATGAGGCCA
GGAACCACTATGGAGGTGTGGTCAGCCTCATCCCCATAGTCCTGGACCTAATGAAAGAGTGGAT
CGCTCATTCCGAGAAGCTGCCTCGCAAAGTGCTGCAGCATGTGAGTGAGATCCTGGGTAACCTG
GCAACTCCAGCACCAGCCGCCACCAGCCCTGCCCAGACCACGGTTACCCAGAAGTGGTTAGGAA
AACACAAGTATAGGCAGCTTGCAAAAGAGAGCCTCAAACCTAGTTCGAAGAACAAAGCCTCCCT
GAAACCTCCCTGGAGGCCGCCTGGTGGGAAACTGTAACTGATGTCAATGTACTTGGCTTCCACT
GGTCATATTCTCACTGGGGGCCAATACACTATTGAGAATCTC

hide sequence

RefSeq Acc Id:

XM_063283481 ⟹ XP_063139551

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	32,417,350 - 32,426,776 (-)	NCBI

RefSeq Acc Id:

XM_063283482 ⟹ XP_063139552

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	32,417,350 - 32,424,741 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001388747	(Get FASTA)	NCBI Sequence Viewer
	NP_859045	(Get FASTA)	NCBI Sequence Viewer
	XP_006233828	(Get FASTA)	NCBI Sequence Viewer
	XP_017447133	(Get FASTA)	NCBI Sequence Viewer
	XP_063139551	(Get FASTA)	NCBI Sequence Viewer
	XP_063139552	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97268	(Get FASTA)	NCBI Sequence Viewer
	AAN07900	(Get FASTA)	NCBI Sequence Viewer
	EDL93399	(Get FASTA)	NCBI Sequence Viewer
	EDL93400	(Get FASTA)	NCBI Sequence Viewer
	EDL93401	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017004
	ENSRNOP00000088937
	ENSRNOP00000095426
GenBank Protein	Q4V8P4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_859045 ⟸ NM_181694
- Peptide Label:	isoform 2
- UniProtKB:	Q7TSB9 (UniProtKB/Swiss-Prot), Q4V8P4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNEVKESLRSIEQKYKLFQQQQFTFIAALEHCRENAHDKIRPISSIEQVQSYMEHYCNNSTDRR ILLMFMDICSELNKLCQHFEALHSGTPVTNSLLEKCKTLVSQSNDLSILRAKYPHDVVNHLSCD EARNHYGGVVSLIPIVLDLMKEWIAHSEKLPRKVLQHGTT hide sequence

RefSeq Acc Id:	XP_006233828 ⟸ XM_006233766
- Peptide Label:	isoform X3
- UniProtKB:	A0A8L2Q9C4 (UniProtKB/TrEMBL), A6JTP7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALGRRERAQSRDSKTSRGAALCERLQGGEETLPVLWDLTATMNEVKESLRSIEQKYKLFQQQQ FTFIAALEHCRENAHDKIRPISSIEQVQSYMEHYCNNSTDRRILLMFMDICSELNKLCQHFEAL HSGTPVTNSLLEKCKTLVSQSNDLSILRAKYPHDVVNHLSCDEARNHYGGVVSLIPIVLDLMKE WIAHSEKLPRKVLQHGTT hide sequence

RefSeq Acc Id:	XP_017447133 ⟸ XM_017591644
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A8T2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNEVKESLRSIEQKYKLFQQQQFTFIAALEHCRENAHDKIRPISSIEQVQSYMEHYCNNSTDRR ILLMFMDICSELNKLCQHFEALHSGTPVTNSLLEKCKTLVSQSNDLSILRAKYPHDVVNHLSCD EARNHYGGVVSLIPIVLDLMKEWIAHSEKLPRKVLQHVSEILGNLATPAPAATSPAQTTVTQKW LGKHKYRQLAKESLKPSSKNKASLKPPWRPPGGKL hide sequence

Ensembl Acc Id:

ENSRNOP00000017004 ⟸ ENSRNOT00000017004

Ensembl Acc Id:

ENSRNOP00000095426 ⟸ ENSRNOT00000112266

Ensembl Acc Id:

ENSRNOP00000088937 ⟸ ENSRNOT00000120222

RefSeq Acc Id:	NP_001388747 ⟸ NM_001401818
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I6A8T2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063139551 ⟸ XM_063283481
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GL53 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063139552 ⟸ XM_063283482
- Peptide Label:	isoform X4
- UniProtKB:	Q7TSB9 (UniProtKB/Swiss-Prot), Q4V8P4 (UniProtKB/Swiss-Prot)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4V8P4-F1-model_v2	AlphaFold	Q4V8P4	1-168	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691936

Promoter ID:

EPDNEW_R2461

Type:

initiation region

Name:

Spaca9_1

Description:

sperm acrosome associated 9

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	7,278,778 - 7,278,838	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727909	AgrOrtholog
BioCyc Gene	G2FUF-50272	BioCyc
Ensembl Genes	ENSRNOG00000012697	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000017004	ENTREZGENE
	ENSRNOT00000112266	ENTREZGENE
	ENSRNOT00000120222	ENTREZGENE
IMAGE_CLONE	IMAGE:7457912	IMAGE-MGC_LOAD
InterPro	SPACA9	UniProtKB/Swiss-Prot
KEGG Report	rno:296610	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114240	IMAGE-MGC_LOAD
NCBI Gene	296610	ENTREZGENE
PANTHER	PTHR32455	UniProtKB/Swiss-Prot
	SPERM ACROSOME-ASSOCIATED PROTEIN 9	UniProtKB/Swiss-Prot
Pfam	SPACA9	UniProtKB/Swiss-Prot
PhenoGen	Spaca9	PhenoGen
RatGTEx	ENSRNOG00000012697	RatGTEx
UniProt	A0A8I6A8T2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GL53	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2Q9C4	ENTREZGENE, UniProtKB/TrEMBL
	A6JTP7	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8P4	ENTREZGENE
	Q7TSB9	ENTREZGENE
	SACA9_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	Q7TSB9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-27	Spaca9	sperm acrosome associated 9	Rsb66	Rsb-66 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-08	Rsb66	Rsb-66 protein			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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