Tenm2 (teneurin transmembrane protein 2) - Rat Genome Database

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Gene: Tenm2 (teneurin transmembrane protein 2) Rattus norvegicus
Analyze
Symbol: Tenm2
Name: teneurin transmembrane protein 2
RGD ID: 727907
Description: Enables cell adhesion molecule binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of filopodium assembly; and retrograde trans-synaptic signaling by trans-synaptic protein complex. Located in dendritic spine and postsynaptic membrane. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic membrane. Orthologous to human TENM2 (teneurin transmembrane protein 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Lasso; LOC102551468; neurestin; odd Oz/ten-m homolog 2; odd Oz/ten-m homolog 2 (Drosophila); odz, odd Oz/ten-m homolog 2; odz, odd Oz/ten-m homolog 2 (Drosophila); Odz2; ten-2; ten-m2; tenascin-M2; teneurin-2; teneurin-2-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81020,984,710 - 22,121,001 (-)NCBIGRCr8
mRatBN7.21020,480,662 - 21,706,415 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1020,481,854 - 21,705,597 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1025,229,591 - 26,365,979 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01024,718,139 - 25,854,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01020,205,571 - 21,341,852 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01020,846,091 - 21,791,771 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,844,899 - 21,265,026 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01020,716,458 - 21,659,087 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41020,939,207 - 21,888,443 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11020,940,255 - 22,096,609 (-)NCBI
Celera1020,101,901 - 21,233,134 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tenm2Ratesophageal atresia  ISOTENM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Esophageal atresiaClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
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Original Reference(s)
Tenm2Ratsubstance-related disorder  ISOTENM2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20098672

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tenm2Rat(-)-demecolcine increases expressionISOTENM2 (Homo sapiens)6480464Demecolcine results in increased expression of TENM2 mRNACTDPMID:23649840
Tenm2Rat17beta-estradiol affects expressionISOTENM2 (Homo sapiens)6480464Estradiol affects the expression of TENM2 mRNACTDPMID:22574217
Tenm2Rat17beta-estradiol multiple interactionsISOTENM2 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of TENM2 mRNACTDPMID:30165855
Tenm2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642 more ...CTDPMID:27291303
Tenm2Rat2,2',5,5'-tetrachlorobiphenyl increases expressionISOTENM2 (Homo sapiens)64804642 more ...CTDPMID:36804509
Tenm2Rat4,4'-sulfonyldiphenol decreases methylationISOTENM2 (Homo sapiens)6480464bisphenol S results in decreased methylation of TENM2 geneCTDPMID:31601247
Tenm2Rat4,4'-sulfonyldiphenol affects methylationISOTenm2 (Mus musculus)6480464bisphenol S affects the methylation of TENM2 geneCTDPMID:31683443
Tenm2Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of TENM2 mRNACTDPMID:24780913
Tenm2Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of TENM2 mRNACTDPMID:31881176
Tenm2Rataflatoxin B1 decreases expressionISOTENM2 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of TENM2 mRNACTDPMID:27153756 and PMID:32234424
Tenm2Rataflatoxin B1 increases methylationISOTENM2 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of TENM2 exon more ...CTDPMID:27153756 and PMID:30157460
Tenm2RatAflatoxin B2 alpha decreases methylationISOTENM2 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of TENM2 intronCTDPMID:30157460
Tenm2Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of TENM2 mRNACTDPMID:16483693
Tenm2Rataristolochic acid A decreases expressionISOTENM2 (Homo sapiens)6480464aristolochic acid I results in decreased expression of TENM2 mRNACTDPMID:33212167
Tenm2Ratarsane affects methylationISOTENM2 (Homo sapiens)6480464Arsenic affects the methylation of TENM2 geneCTDPMID:25304211
Tenm2Ratarsane multiple interactionsISOTENM2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of TENM2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TENM2 mRNACTDPMID:39836092
Tenm2Ratarsenic atom affects methylationISOTENM2 (Homo sapiens)6480464Arsenic affects the methylation of TENM2 geneCTDPMID:25304211
Tenm2Ratarsenic atom multiple interactionsISOTENM2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of TENM2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TENM2 mRNACTDPMID:39836092
Tenm2Ratarsenous acid increases expressionISOTENM2 (Homo sapiens)6480464Arsenic Trioxide results in increased expression of TENM2 mRNACTDPMID:20458559
Tenm2Ratatrazine affects methylationEXP 6480464Atrazine affects the methylation of TENM2 geneCTDPMID:35440735

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Biological Process

  
Object Symbol
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Original Reference(s)
Tenm2Ratcell adhesion involved_inIEAUniProtKB-KW:KW-01301600115GO_REF:0000043UniProtGO_REF:0000043
Tenm2Ratcell-cell adhesion involved_inISSUniProtKB:Q9DER51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratnegative regulation of transcription by RNA polymerase II involved_inISSUniProtKB:Q9DER51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratneuron development involved_inIBAPANTHER:PTN000131466 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tenm2Ratpositive regulation of filopodium assembly involved_inISSUniProtKB:Q9DER51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratretrograde trans-synaptic signaling by trans-synaptic protein complex involved_inISOTENM2 (Homo sapiens)1624291 PMID:21724987RGDPMID:21724987
Tenm2Ratretrograde trans-synaptic signaling by trans-synaptic protein complex involved_inIEAUniProtKB:Q9NT68 and ensembl:ENSP000004294301600115GO_REF:0000107EnsemblGO_REF:0000107
Tenm2Ratsignal transduction involved_inIEAInterPro:IPR0094711600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component
1 to 20 of 45 rows

  
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Original Reference(s)
Tenm2Ratcell junction located_inISSUniProtKB:Q9DER51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratcell projection located_inIEAUniProtKB-SubCell:SL-02801600115GO_REF:0000044UniProtGO_REF:0000044
Tenm2Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Tenm2Ratcell-cell junction located_inISSUniProtKB:Q9NT68-21600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratcell-cell junction located_inISOTENM2 (Homo sapiens) and UniProtKB:Q9NT68-21624291 PMID:21724987RGDPMID:21724987
Tenm2Ratdendrite located_inISSUniProtKB:Q9DER51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratdendritic spine located_inIDA 8553824PMID:21724987UniProt 
Tenm2Ratdendritic spine located_inIEAUniProtKB-SubCell:SL-02841600115GO_REF:0000044UniProtGO_REF:0000044
Tenm2Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Tenm2Ratendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-00951600115GO_REF:0000044UniProtGO_REF:0000044
Tenm2Ratendoplasmic reticulum located_inISSUniProtKB:Q9DER51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratextrinsic component of postsynaptic membrane is_active_inIDA 8553824PMID:21724987SynGO 
Tenm2Ratextrinsic component of postsynaptic membrane is_active_inIEP 8553824PMID:21724987SynGO 
Tenm2Ratextrinsic component of postsynaptic membrane is_active_inIMP 8553824PMID:21724987SynGO 
Tenm2Ratfilopodium located_inISSUniProtKB:Q9DER51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratfilopodium located_inIEAUniProtKB-SubCell:SL-02861600115GO_REF:0000044UniProtGO_REF:0000044
Tenm2Ratglutamatergic synapse is_active_inIDA 8553824PMID:21724987SynGO 
Tenm2Ratglutamatergic synapse is_active_inIEP 8553824PMID:21724987SynGO 
Tenm2Ratglutamatergic synapse is_active_inIMP 8553824PMID:21724987SynGO 
Tenm2RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
1 to 20 of 45 rows

Molecular Function
1 to 16 of 16 rows

  
Object Symbol
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Original Reference(s)
Tenm2Ratcalcium ion binding enablesIEAInterPro:IPR0018811600115GO_REF:0000002InterProGO_REF:0000002
Tenm2Ratcell adhesion molecule binding enablesIDA 8553824PMID:21724987UniProt 
Tenm2Ratcell adhesion molecule binding enablesIBAPANTHER:PTN000131466 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tenm2Ratcell adhesion molecule binding enablesISOTENM2 (Homo sapiens) and UniProtKB:Q9NT68-21624291 PMID:21724987RGDPMID:21724987
Tenm2Ratidentical protein binding enablesISOTenm2 (Mus musculus)1624291PR:Q9WTS5 PMID:12000766RGDPMID:12000766
Tenm2Ratprotein binding enablesIPIUniProtKB:O88917-28553824PMID:21724987UniProt 
Tenm2Ratprotein binding enablesISOTenm2 (Mus musculus)1624291PR:Q9WTS4 more ...RGDPMID:12000766
Tenm2Ratprotein binding enablesISOTENM2 (Homo sapiens) and UniProtKB:Q9NT68-21624291UniProtKB:O88917-2 and PMID:21724987RGDPMID:21724987
Tenm2Ratprotein heterodimerization activity enablesISSUniProtKB:Q9WTS51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratprotein heterodimerization activity enablesISOTenm2 (Mus musculus)1624291 PMID:12000766RGDPMID:12000766
Tenm2Ratprotein heterodimerization activity enablesIBAMGI:1345183 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tenm2Ratprotein homodimerization activity enablesISSUniProtKB:Q9WTS51600115GO_REF:0000024UniProtGO_REF:0000024
Tenm2Ratprotein homodimerization activity enablesIBAMGI:1345184 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tenm2Ratprotein homodimerization activity enablesISOTenm2 (Mus musculus)1624291 PMID:12000766RGDPMID:12000766
Tenm2Ratsignaling receptor binding enablesISOTENM2 (Homo sapiens) and UniProtKB:Q9NT68-21624291 PMID:21724987RGDPMID:21724987
Tenm2Ratsignaling receptor binding enablesIDA 8553824PMID:21724987UniProt 
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
4. Neurestin: putative transmembrane molecule implicated in neuronal development. Otaki JM and Firestein S, Dev Biol 1999 Aug 1;212(1):165-81.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities. Silva JP, etal., Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12113-8. doi: 10.1073/pnas.1019434108. Epub 2011 Jul 1.
PMID:12000766  



Tenm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81020,984,710 - 22,121,001 (-)NCBIGRCr8
mRatBN7.21020,480,662 - 21,706,415 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1020,481,854 - 21,705,597 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1025,229,591 - 26,365,979 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01024,718,139 - 25,854,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01020,205,571 - 21,341,852 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01020,846,091 - 21,791,771 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,844,899 - 21,265,026 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01020,716,458 - 21,659,087 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41020,939,207 - 21,888,443 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11020,940,255 - 22,096,609 (-)NCBI
Celera1020,101,901 - 21,233,134 (-)NCBICelera
Cytogenetic Map10q12NCBI
TENM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385166,979,029 - 168,264,157 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5166,979,029 - 168,264,157 (+)EnsemblGRCh38hg38GRCh38
GRCh375166,406,034 - 167,691,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365167,114,519 - 167,623,740 (+)NCBINCBI36Build 36hg18NCBI36
Build 345167,477,951 - 167,623,739NCBI
Celera5162,750,499 - 163,726,534 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5161,812,425 - 162,791,103 (+)NCBIHuRef
CHM1_15166,144,311 - 167,124,193 (+)NCBICHM1_1
T2T-CHM13v2.05167,513,669 - 168,798,988 (+)NCBIT2T-CHM13v2.0
Tenm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,897,483 - 37,881,486 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,897,483 - 37,126,791 (-)EnsemblGRCm39 Ensembl
GRCm381136,006,656 - 37,237,053 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1136,006,656 - 37,235,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv371135,820,171 - 36,757,745 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361135,851,071 - 36,787,666 (-)NCBIMGSCv36mm8
Celera1140,009,205 - 40,811,666 (-)NCBICelera
Cytogenetic Map11A4- A5NCBI
cM Map1121.96NCBI
Tenm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540820,437,067 - 21,338,897 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540820,150,223 - 21,340,276 (+)NCBIChiLan1.0ChiLan1.0
TENM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24160,186,848 - 163,424,969 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15158,326,399 - 161,564,515 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05162,346,710 - 163,627,371 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15169,420,475 - 170,392,593 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5169,420,480 - 170,392,581 (+)Ensemblpanpan1.1panPan2
TENM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1443,450,278 - 44,962,993 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl443,451,059 - 44,377,371 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha443,408,748 - 44,060,223 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0443,873,657 - 44,519,117 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl443,874,738 - 44,793,811 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1443,643,674 - 44,287,381 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0443,838,128 - 44,482,532 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0444,344,597 - 44,989,412 (-)NCBIUU_Cfam_GSD_1.0
Tenm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721397,485,971 - 98,368,217 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366221,102,963 - 1,983,751 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366221,101,587 - 1,983,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TENM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1655,625,320 - 56,620,257 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11655,624,273 - 59,084,150 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21660,189,355 - 61,223,392 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TENM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12369,206,076 - 70,487,159 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660348,199,738 - 9,519,849 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tenm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473321,732,787 - 22,627,526 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473321,732,997 - 22,921,889 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Tenm2
8261 total Variants

Predicted Target Of
Summary Value
Count of predictions:302
Count of miRNA genes:115
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000011922, ENSRNOT00000068312
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 34 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat

1 to 10 of 34 rows
D10Mit5  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01021,523,906 - 21,524,070NCBIRnor6.0
Rnor_5.01021,392,295 - 21,392,459UniSTSRnor5.0
RGSC_v3.41021,607,719 - 21,607,865RGDRGSC3.4
RGSC_v3.41021,607,720 - 21,607,865UniSTSRGSC3.4
RGSC_v3.11021,608,769 - 21,608,914RGD
RH 3.4 Map10240.41UniSTS
RH 3.4 Map10240.41RGD
RH 2.0 Map10246.1RGD
Cytogenetic Map10q12UniSTS
D10Rat42  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81021,833,758 - 21,833,887 (+)Marker Load Pipeline
mRatBN7.21021,329,805 - 21,330,072 (+)MAPPERmRatBN7.2
mRatBN7.21021,329,805 - 21,329,934 (+)MAPPERmRatBN7.2
Rnor_6.01021,707,766 - 21,708,067NCBIRnor6.0
Rnor_6.01021,707,766 - 21,707,894NCBIRnor6.0
Rnor_5.01021,575,051 - 21,575,352UniSTSRnor5.0
Rnor_5.01021,575,051 - 21,575,179UniSTSRnor5.0
RH 3.4 Map10240.11RGD
RH 3.4 Map10240.11UniSTS
RH 2.0 Map10251.9RGD
SHRSP x BN Map1027.23RGD
FHH x ACI Map1015.2RGD
Cytogenetic Map10q12UniSTS
D10Rat75  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81021,280,441 - 21,280,573 (+)Marker Load Pipeline
mRatBN7.21020,776,430 - 20,776,562 (+)MAPPERmRatBN7.2
Rnor_6.01021,140,054 - 21,140,185NCBIRnor6.0
Rnor_5.01021,008,287 - 21,008,418UniSTSRnor5.0
RGSC_v3.41021,235,991 - 21,236,123RGDRGSC3.4
RGSC_v3.41021,235,992 - 21,236,123UniSTSRGSC3.4
RGSC_v3.11021,237,040 - 21,237,172RGD
Celera1020,395,511 - 20,395,642UniSTS
SHRSP x BN Map1026.1499UniSTS
SHRSP x BN Map1026.1499RGD
Cytogenetic Map10q12UniSTS
D10Rat179  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01021,236,996 - 21,237,161NCBIRnor6.0
Rnor_5.01021,105,195 - 21,105,360UniSTSRnor5.0
RGSC_v3.41021,332,818 - 21,333,025RGDRGSC3.4
RGSC_v3.41021,332,819 - 21,333,025UniSTSRGSC3.4
RGSC_v3.11021,333,867 - 21,334,074RGD
Celera1020,491,739 - 20,491,934UniSTS
SHRSP x BN Map1027.31UniSTS
SHRSP x BN Map1027.31RGD
Cytogenetic Map10q12UniSTS
D11Mit232  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,526,569 - 20,526,750 (+)MAPPERmRatBN7.2
Rnor_6.01020,890,843 - 20,891,023NCBIRnor6.0
Rnor_5.01020,761,210 - 20,761,390UniSTSRnor5.0
RGSC_v3.41020,983,922 - 20,984,102UniSTSRGSC3.4
Celera1020,146,552 - 20,146,719UniSTS
Cytogenetic Map10q12UniSTS
BE102452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,499,028 - 20,499,194 (+)MAPPERmRatBN7.2
Rnor_6.01020,863,306 - 20,863,471NCBIRnor6.0
Rnor_5.01020,733,673 - 20,733,838UniSTSRnor5.0
RGSC_v3.41020,956,384 - 20,956,549UniSTSRGSC3.4
Celera1020,119,074 - 20,119,239UniSTS
RH 3.4 Map10214.33UniSTS
Cytogenetic Map10q12UniSTS
RH138576  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,481,529 - 20,481,726 (+)MAPPERmRatBN7.2
Rnor_6.01020,845,767 - 20,845,963NCBIRnor6.0
Rnor_5.01020,716,134 - 20,716,330UniSTSRnor5.0
RGSC_v3.41020,938,883 - 20,939,079UniSTSRGSC3.4
Celera1020,101,577 - 20,101,773UniSTS
RH 3.4 Map10215.72UniSTS
Cytogenetic Map10q12UniSTS
D3Bwg1534e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,481,842 - 20,482,055 (+)MAPPERmRatBN7.2
Rnor_6.01020,846,080 - 20,846,292NCBIRnor6.0
Rnor_5.01020,716,447 - 20,716,659UniSTSRnor5.0
RGSC_v3.41020,939,196 - 20,939,408UniSTSRGSC3.4
Celera1020,101,890 - 20,102,102UniSTS
Cytogenetic Map10q12UniSTS
RH144521  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81021,139,330 - 21,139,514 (+)Marker Load Pipeline
mRatBN7.21020,635,298 - 20,635,482 (+)MAPPERmRatBN7.2
Rnor_6.01022,105,801 - 22,105,984NCBIRnor6.0
Rnor_6.01020,998,936 - 20,999,119NCBIRnor6.0
Rnor_5.01020,866,384 - 20,866,567UniSTSRnor5.0
Rnor_5.01021,971,053 - 21,971,236UniSTSRnor5.0
RGSC_v3.41021,093,062 - 21,093,245UniSTSRGSC3.4
Celera1020,254,868 - 20,255,051UniSTS
RH 3.4 Map10241.11UniSTS
Cytogenetic Map10q12UniSTS
BE096193  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21021,131,025 - 21,131,224 (+)MAPPERmRatBN7.2
Rnor_6.01021,507,177 - 21,507,375NCBIRnor6.0
Rnor_5.01021,375,566 - 21,375,764UniSTSRnor5.0
RGSC_v3.41021,591,079 - 21,591,277UniSTSRGSC3.4
Celera1020,748,252 - 20,748,450UniSTS
RH 3.4 Map10239.4UniSTS
Cytogenetic Map10q12UniSTS
AI501498  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,949,883 - 20,950,071 (+)MAPPERmRatBN7.2
Rnor_6.01021,314,944 - 21,315,131NCBIRnor6.0
Rnor_5.01021,182,663 - 21,182,850UniSTSRnor5.0
RGSC_v3.41021,410,540 - 21,410,727UniSTSRGSC3.4
Celera1020,568,102 - 20,568,289UniSTS
RH 3.4 Map10235.7UniSTS
Cytogenetic Map10q12UniSTS
AW529537  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21021,044,921 - 21,045,131 (+)MAPPERmRatBN7.2
Rnor_6.01021,420,490 - 21,420,699NCBIRnor6.0
Rnor_5.01021,287,635 - 21,287,844UniSTSRnor5.0
Celera1020,662,181 - 20,662,390UniSTS
RH 3.4 Map10241.7UniSTS
Cytogenetic Map10q12UniSTS
AU049925  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21021,330,407 - 21,330,599 (+)MAPPERmRatBN7.2
Rnor_6.01021,708,541 - 21,708,732NCBIRnor6.0
Rnor_5.01021,575,826 - 21,576,017UniSTSRnor5.0
RGSC_v3.41021,791,994 - 21,792,185UniSTSRGSC3.4
Celera1020,947,151 - 20,947,312UniSTS
Cytogenetic Map10q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 38 113 87 86 55 25 55 6 201 85 93 44 60 31


1 to 20 of 20 rows
RefSeq Transcripts NM_020088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF086607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF086608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF086609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF086610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 20 of 20 rows

Ensembl Acc Id: ENSRNOT00000011922   ⟹   ENSRNOP00000011922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1020,481,854 - 21,705,597 (-)Ensembl
Rnor_6.0 Ensembl1020,844,899 - 21,265,026 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097791   ⟹   ENSRNOP00000077386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1020,481,854 - 21,705,597 (-)Ensembl
RefSeq Acc Id: NM_020088   ⟹   NP_064473
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,985,902 - 22,120,940 (-)NCBI
mRatBN7.21020,481,854 - 21,617,003 (-)NCBI
Rnor_6.01020,846,091 - 21,791,771 (-)NCBI
Rnor_5.01020,716,458 - 21,659,087 (-)NCBI
RGSC_v3.41020,939,207 - 21,888,443 (-)RGD
Celera1020,101,901 - 21,233,134 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085063   ⟹   XP_038940991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,121,001 (-)NCBI
mRatBN7.21020,482,113 - 21,706,415 (-)NCBI
RefSeq Acc Id: XM_039085066   ⟹   XP_038940994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,121,001 (-)NCBI
mRatBN7.21020,482,113 - 21,705,812 (-)NCBI
RefSeq Acc Id: XM_039085068   ⟹   XP_038940996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,121,001 (-)NCBI
mRatBN7.21020,482,113 - 21,705,812 (-)NCBI
RefSeq Acc Id: XM_039085069   ⟹   XP_038940997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,121,001 (-)NCBI
mRatBN7.21020,482,113 - 21,705,812 (-)NCBI
RefSeq Acc Id: XM_039085070   ⟹   XP_038940998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,121,001 (-)NCBI
mRatBN7.21020,482,113 - 21,705,812 (-)NCBI
RefSeq Acc Id: XM_039085071   ⟹   XP_038940999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,121,001 (-)NCBI
mRatBN7.21020,482,113 - 21,705,811 (-)NCBI
RefSeq Acc Id: XM_039085072   ⟹   XP_038941000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 21,667,732 (-)NCBI
mRatBN7.21020,482,113 - 21,163,766 (-)NCBI
RefSeq Acc Id: XM_039085074   ⟹   XP_038941002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 21,419,039 (-)NCBI
mRatBN7.21020,482,113 - 20,905,100 (-)NCBI
RefSeq Acc Id: XM_039085075   ⟹   XP_038941003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 21,419,039 (-)NCBI
mRatBN7.21020,482,113 - 20,905,100 (-)NCBI
RefSeq Acc Id: XM_039085076   ⟹   XP_038941004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 21,667,733 (-)NCBI
mRatBN7.21020,482,113 - 21,163,766 (-)NCBI
RefSeq Acc Id: XM_063268319   ⟹   XP_063124389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,001,337 (-)NCBI
RefSeq Acc Id: XM_063268320   ⟹   XP_063124390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 22,121,001 (-)NCBI
RefSeq Acc Id: XM_063268321   ⟹   XP_063124391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 21,667,733 (-)NCBI
RefSeq Acc Id: XM_063268322   ⟹   XP_063124392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,984,710 - 21,667,732 (-)NCBI
1 to 5 of 17 rows
1 to 5 of 17 rows
RefSeq Acc Id: NP_064473   ⟸   NM_020088
- UniProtKB: A6HDJ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011922   ⟸   ENSRNOT00000011922
RefSeq Acc Id: XP_038940991   ⟸   XM_039085063
- Peptide Label: isoform X1
- UniProtKB: Q9R1K2 (UniProtKB/Swiss-Prot),   Q9R1K1 (UniProtKB/Swiss-Prot),   Q9R1K0 (UniProtKB/Swiss-Prot),   Q9R1J9 (UniProtKB/Swiss-Prot),   A0A096P6L6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940998   ⟸   XM_039085070
- Peptide Label: isoform X5
- UniProtKB: Q9R1K2 (UniProtKB/Swiss-Prot),   Q9R1K1 (UniProtKB/Swiss-Prot),   Q9R1K0 (UniProtKB/Swiss-Prot),   Q9R1J9 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038940997   ⟸   XM_039085069
- Peptide Label: isoform X4
- UniProtKB: Q9R1K2 (UniProtKB/Swiss-Prot),   Q9R1K1 (UniProtKB/Swiss-Prot),   Q9R1K0 (UniProtKB/Swiss-Prot),   Q9R1J9 (UniProtKB/Swiss-Prot)
EGF-like   Teneurin N-terminal


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 47 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-25535 BioCyc
Ensembl Genes ENSRNOG00000027341 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000011922 ENTREZGENE
  ENSRNOT00000097791 ENTREZGENE
  ENSRNOT00000132901 ENTREZGENE
  ENSRNOT00000146782 ENTREZGENE
  ENSRNOT00000171102 ENTREZGENE
  ENSRNOT00000173444 ENTREZGENE
Gene3D-CATH 2.120.10.30 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
  RHS repeat-associated core UniProtKB/Swiss-Prot
InterPro 6-blade_b-propeller_TolB-like UniProtKB/Swiss-Prot
  CarboxyPept-like_regulatory UniProtKB/Swiss-Prot
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  IPR006530 UniProtKB/Swiss-Prot
  Rhs_assc_core UniProtKB/Swiss-Prot
  Ten_N UniProtKB/Swiss-Prot
  Teneurin_domain UniProtKB/Swiss-Prot
  Tox-GHH_dom UniProtKB/Swiss-Prot
KEGG Report rno:117242 UniProtKB/Swiss-Prot
NCBI Gene 117242 ENTREZGENE
PANTHER PTHR11219:SF8 UniProtKB/Swiss-Prot
  TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE UniProtKB/Swiss-Prot
Pfam Ten_N UniProtKB/Swiss-Prot
  Tox-GHH UniProtKB/Swiss-Prot
PhenoGen Tenm2 PhenoGen
PROSITE EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  TENEURIN_N UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000027341 RatGTEx
SMART EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
Superfamily-SCOP DPP6 N-terminal domain-like UniProtKB/Swiss-Prot
  NHL repeat UniProtKB/Swiss-Prot
  SSF49464 UniProtKB/Swiss-Prot
UniProt A0A096P6L6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y1H9 ENTREZGENE, UniProtKB/TrEMBL
  A6HDJ4 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 47 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Tenm2  teneurin transmembrane protein 2  LOC102551468  teneurin-2-like  Data merged from RGD:7596091 737654 PROVISIONAL
2013-12-18 LOC102551468  teneurin-2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-10-11 Tenm2  teneurin transmembrane protein 2  Odz2  odz, odd Oz/ten-m homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Odz2  odz, odd Oz/ten-m homolog 2 (Drosophila)  Odz2  odd Oz/ten-m homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Odz2  odd Oz/ten-m homolog 2 (Drosophila)      Symbol and Name status set to approved 1299863 APPROVED

Note Type Note Reference
gene_expression expressed in many types of neurons, including pyramidal cells in the cerebral cortex and tufted cells in the olfactory bulb during development 1299591