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Gene: Plppr3 (phospholipid phosphatase related 3) Rattus norvegicus

Analyze

Symbol:

Plppr3

Name:

phospholipid phosphatase related 3

RGD ID:

727823

Description:

Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human PLPPR3 (phospholipid phosphatase related 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

inactive phospholipid phosphatase PLPPR3; lipid phosphate phosphatase-related protein type 3; Lppr3; phospholipid phosphatase-related protein type 3; plasticity-related gene 2; plasticity-related protein PRG-2; plasticity-related protein PRG-2-like; Prg-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLPPR3 (phospholipid phosphatase related 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Plppr3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Plppr3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PLPPR3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PLPPR3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Plppr3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PLPPR3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PLPPR3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Plppr3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Plppr3 (phospholipid phosphatase related 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CYP2F1 (cytochrome P450 family 2 subfamily F member 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PLPPR3 (phospholipid phosphatase related 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Plppr3 (phospholipid phosphatase related 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	plppr3b (phospholipid phosphatase related 3b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	plppr3a (phospholipid phosphatase related 3a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plpr-1	Alliance	DIOPT (Hieranoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plpr-1	Alliance	DIOPT (OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	plppr3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	plppr3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,481,624 - 10,493,059 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	10,481,636 - 10,495,921 (+)	Ensembl				GRCr8
mRatBN7.2	7	9,831,162 - 9,842,434 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,831,162 - 9,845,296 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	12,711,880 - 12,723,142 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,589,961 - 14,601,225 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,449,629 - 12,461,116 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,652,555 - 12,663,825 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,652,415 - 12,663,819 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	12,822,277 - 12,833,539 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	11,344,163 - 11,355,318 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	8,005,921 - 8,017,136 (+)	NCBI		Celera
RGSC_v3.1	7	11,344,162 - 11,355,319 (+)	NCBI
Cytogenetic Map	7	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,4'-trichlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

bromobenzene (EXP)

Butylbenzyl phthalate (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

Cuprizon (EXP)

DDE (ISO)

dibutyl phthalate (EXP)

diethyl phthalate (EXP)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

furan (EXP)

gentamycin (EXP)

glycidol (EXP)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

N-methyl-4-phenylpyridinium (EXP)

okadaic acid (ISO)

paracetamol (EXP)

PCB138 (ISO)

propanal (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thimerosal (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

phospholipid dephosphorylation (IBA)

phospholipid metabolic process (IBA,IEA)

signal transduction (IBA)

Cellular Component

membrane (IEA)

plasma membrane (IBA)

Molecular Function

phosphatidate phosphatase activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12730698	PMID:28131823

Genomics

Comparative Map Data

Plppr3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,481,624 - 10,493,059 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	10,481,636 - 10,495,921 (+)	Ensembl				GRCr8
mRatBN7.2	7	9,831,162 - 9,842,434 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,831,162 - 9,845,296 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	12,711,880 - 12,723,142 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,589,961 - 14,601,225 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,449,629 - 12,461,116 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,652,555 - 12,663,825 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,652,415 - 12,663,819 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	12,822,277 - 12,833,539 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	11,344,163 - 11,355,318 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	8,005,921 - 8,017,136 (+)	NCBI		Celera
RGSC_v3.1	7	11,344,162 - 11,355,319 (+)	NCBI
Cytogenetic Map	7	q11	NCBI

PLPPR3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	812,488 - 823,797 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	812,487 - 822,619 (-)	Ensembl			hg38	GRCh38
GRCh37	19	812,488 - 821,955 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	763,518 - 772,952 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	317 - 3,691 (+)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	581,917 - 590,577 (-)	NCBI		HuRef
CHM1_1	19	812,082 - 821,550 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	766,962 - 778,213 (-)	NCBI		T2T-CHM13v2.0

Plppr3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	79,696,309 - 79,710,948 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	79,696,309 - 79,710,468 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	79,860,475 - 79,874,958 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	79,860,475 - 79,874,634 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	79,323,220 - 79,337,379 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,267,910 - 79,277,763 (-)	NCBI		MGSCv36	mm8
Celera	10	80,875,288 - 80,889,447 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Plppr3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	6,980,549 - 6,994,046 (+)	Ensembl
ChiLan1.0	NW_004955495	6,980,213 - 6,990,331 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLPPR3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	5,143,309 - 5,152,509 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	4,381,214 - 4,391,015 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	309,998 - 319,779 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	780,559 - 784,980 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

PLPPR3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,800,998 - 57,806,233 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	57,800,740 - 57,806,246 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	57,603,009 - 57,608,185 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	58,543,284 - 58,548,457 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	58,543,102 - 58,590,831 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	57,597,936 - 57,603,123 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	58,077,693 - 58,082,876 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	58,280,740 - 58,285,903 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Plppr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	217,501,491 - 217,507,690 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	323,864 - 333,031 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	327,089 - 333,267 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLPPR3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	77,538,969 - 77,551,785 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	77,538,925 - 77,552,046 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	78,292,948 - 78,360,010 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLPPR3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	560,961 - 571,202 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	558,495 - 570,619 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666403	2,151 - 38,298 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plppr3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	7,741,126 - 7,753,973 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624828	7,740,766 - 7,750,608 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Plppr3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	154,998,152 - 155,012,709 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Plppr3
143 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	63
Count of miRNA genes:	59
Interacting mature miRNAs:	63
Transcripts:	ENSRNOT00000031315
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1669658	46669658	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	1	23748937	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	7216097	52216097	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
2290372	Gluco33	Glucose level QTL 33	2.71		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	1	31777942	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1709527	46709527	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	32612984	Rat
1582260	Bw72	Body weight QTL 72	3.2	0.0043	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582261	Bw69	Body weight QTL 69	3.2	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582262	Bw75	Body weight QTL 75	3	0.0038	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	10112916	60150541	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	9460877	54460877	Rat
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	29716167	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34650782	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	32612984	Rat

Markers in Region

RH128371

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	49,050,008 - 49,050,188 (+)	MAPPER	mRatBN7.2
mRatBN7.2	7	9,842,584 - 9,842,764 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	12,663,976 - 12,664,155	NCBI	Rnor6.0
Rnor_6.0	11	51,494,714 - 51,494,893	NCBI	Rnor6.0
Rnor_5.0	11	54,674,121 - 54,674,300	UniSTS	Rnor5.0
Rnor_5.0	7	12,833,698 - 12,833,877	UniSTS	Rnor5.0
RGSC_v3.4	11	50,177,629 - 50,177,808	UniSTS	RGSC3.4
RGSC_v3.4	7	11,355,477 - 11,355,656	UniSTS	RGSC3.4
Celera	7	8,017,287 - 8,017,466	UniSTS
Celera	11	48,716,420 - 48,716,599	UniSTS
Cytogenetic Map	7	q11	UniSTS

Ptb

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	49,050,033 - 49,050,190 (+)	MAPPER	mRatBN7.2
mRatBN7.2	7	9,842,609 - 9,842,766 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	51,494,739 - 51,494,895	NCBI	Rnor6.0
Rnor_6.0	7	12,664,001 - 12,664,157	NCBI	Rnor6.0
Rnor_5.0	11	54,674,146 - 54,674,302	UniSTS	Rnor5.0
Rnor_5.0	7	12,833,723 - 12,833,879	UniSTS	Rnor5.0
RGSC_v3.4	11	50,177,654 - 50,177,810	UniSTS	RGSC3.4
RGSC_v3.4	7	11,355,502 - 11,355,658	UniSTS	RGSC3.4
Celera	7	8,017,312 - 8,017,468	UniSTS
Celera	11	48,716,445 - 48,716,601	UniSTS
Cytogenetic Map	7	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	66	160	86	85	54	52	54	6	304	150	11	139	76	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_181634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC129083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC167750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000031315 ⟹ ENSRNOP00000029601

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	10,481,636 - 10,493,052 (+)	Ensembl
mRatBN7.2 Ensembl	7	9,831,162 - 9,842,434 (+)	Ensembl
Rnor_6.0 Ensembl	7	12,652,415 - 12,663,819 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093196 ⟹ ENSRNOP00000076351

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,831,323 - 9,842,428 (+)	Ensembl
Rnor_6.0 Ensembl	7	12,652,716 - 12,663,819 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093350

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	12,652,683 - 12,663,819 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094347 ⟹ ENSRNOP00000084313

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	10,481,636 - 10,495,921 (+)	Ensembl
mRatBN7.2 Ensembl	7	9,831,162 - 9,845,296 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134760 ⟹ ENSRNOP00000108014

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	10,481,636 - 10,493,106 (+)	Ensembl

RefSeq Acc Id:

NM_181634 ⟹ NP_853665

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,481,789 - 10,493,059 (+)	NCBI
mRatBN7.2	7	9,831,162 - 9,842,434 (+)	NCBI
Rnor_6.0	7	12,652,555 - 12,663,825 (+)	NCBI
Rnor_5.0	7	12,822,277 - 12,833,539 (+)	NCBI
RGSC_v3.4	7	11,344,163 - 11,355,318 (+)	RGD
Celera	7	8,005,921 - 8,017,136 (+)	NCBI

Sequence:

show sequence

TCCCGCACCTCCCTTCCCCAAGTTTCCCCCTTCTGCTCCAGCCTCAGTTTCCCCGAGCCTTCTG
ACCAGGAGCCAGGGCTAGCCCTTATCTCCCCACCTGGAGACTCCATCTGCGCACCAACTAGTCT
CCAGCCTGCCTTTGTCCCCCTGCAACCTCGGCCTACAGCGCCAGCGTCACCATGATTGCTAAGA
AGGAGAAGAATAAAACGCCGAAGGACAGCATGACGCTCCTACCTTGCTTTTATTTCGTGGAGCT
ACCCATCGTGGCTTCCTCTGTTGTGTCTCTGTACTTCCTGGAGCTGACTGACCTGTTCCAGCCG
GCTAAGGTGGGCTTTCAGTGCCACGACCGCTCCCTGTCCATGCCCTACGTGGAGACAAACGAAG
AACTGATTCCACTGCTCATGTTGCTGAGCCTGGCCTTTGCTGCACCCGCGGCCTCCATCATGGT
CGGCGAGGGCATGGTCTACTGTCTGCAGTCCAGGCTCTGGGGCCGAGGTCCAGGGGGTGTAGAG
GGCAGCATCAATGCTGGTGGCTGCAACTTCAACTCCTTCCTCCGGCGCACAGTGCGCTTTGTGG
GTGTACACGTGTTTGGCCTGTGTGCCACGGCTCTGGTGACAGATGTCATCCAGCTGGCCACCGG
CTACCACACACCTTTCTTCCTAACCGTCTGCAAACCCAATTACACCCTGCTGGGCACTTCCTGT
GAGGCGAACCCTTACATCACACAGGACATCTGCTCTGGCCATGATACTCATGCCATCCTGTCAG
CACGGAAGACCTTCCCATCCCAGCACGCCACTCTGTCCGCCTTCGCTGCTGTCTACGTTTCGAT
GTACTTCAACTCCGTTATCTCGGACGCCACAAAGCTGCTGAAACCCATCCTTGTGTTCGCCTTC
GCCATCGCCGCTGGCGTCTGTGGCCTCACACAGATCACCCAGTACCGCAGTCACCCTGTGGACG
TCTACGCCGGCTTCCTTATTGGTGCAGGCATTGCTGCCTACCTGGCCTGCCACGCGGTGGGCAA
CTTCCAGGCGTCACCTGCAGAAAAGGTGCCCGCCCCAGCTCCTGCCAAGGACGCCCTTCGAGTG
CTGACACAGCGCGGCCATGAGTCCATGTATCAGCAGAATAAGTCTGTCAGCACAGATGAGCTGG
GCCCTCCGGGGAGGTTAGAGGGTGTGCCTCGGCCTGTGGCTAGAGAGAAGACATCTCTTGGCAG
CCTGAAGCGAGCCAGCGTGGATGTAGACCTGCTGGCCCCACGCAGCCCCATGGGCAAAGAGGGC
ATGGTCACCTTCAGCAACACACTGCCCCGGGTCAGCACGCCCTCGCTGGATGACCCTTCCCGGC
GACACATGACTATCCACGTGCCCCTTGATGCCTCGCGCTCCAGGCAGCTGATCAGTGAGTGGAA
GCAAAAGTCTCTGGAGGGTCGTGGCCTGGGGCTGCCTGATGAGGCTAGCCCTGCGCATCTGCGG
GCCCCAGCAGAGCAGGTGGCAGAGGAAGAAGAGGAAGAGGAGGAGGAGGAAGAGGAGGAAGAAG
AGGAAGAGGAGGAGGAGGAAGGGCCTGTTCCACCCTCGCTCTACCCCACTGTCCAGGCTCGGCC
AGGGCTCGGGCCCCGAGTCATCCTGCCTCCAAGGCCTGGGCCCCAGCCCCTCATCCACATCCCT
GAGGAAGTAGTTCAGGCTGGAGCTGGCCTGTCACCCAAGAGCAGTGCATCAGTGCGGGCCAAGT
GGCTGTCAATGGTGGAGAAGGGTGGGGGCCCAGTGGCTGTGGCTCCACCACAGCCACGGGTGGC
CAACCCACCGAGGCTACTACAGGTCATTGCCATGTCCAAGGCAGCAGGGGGCCCCAAGGCTGAG
ACAGCTTCCTCCTCCAGTGCCAGCTCCGACTCTTCCCAGTACAGGTCCCCATCAGACCGGGACT
CTGCCAGCATCGTCACAATTGATGCACATGCACCCCACCACCCGGTGGTGCACCTGTCTGCGGG
CAGCACACCCTGGGAGTGGAAGGCCAAAGTGGTGGAGGGGGAAGGTGGCTATGAGCTGGGGGAC
CTGGCGCGTGGGTTCAGAAGCAGCTGCAAACAGCCTGGAATTGGCCCAGGGTCTCCAGTCAGTG
ATGTGGACCAGGAGGAACCCCGGTTTGGGGCTGTGGCCACCGTCAACCTGGCCACTGGGGAGGG
TCTGCCCCCACCAGGTGCAAGTGAAGGGGCCCTGGGTGCAGGCAGCAGGGAATCCACCCTGAGA
CGCCAGGTGGGGGCGCTGGGGGAGAGAGAAGTGGAGGCAGAGGCAGAAAGCTACTACAGAAGGA
TGCAGGCCAGGAGGTACCAGGACTAAGCCTGGCAAAGCTGTGATGGGCAGAAGGCAGGCTGGGG
GTCACTACAGCCCCACCAATAAAGGTTCATGGTAACCGTTATGTGGT

hide sequence

RefSeq Acc Id:

XM_063263410 ⟹ XP_063119480

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,481,624 - 10,493,053 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_853665	(Get FASTA)	NCBI Sequence Viewer
	XP_063119480	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI67750	(Get FASTA)	NCBI Sequence Viewer
	EDL89380	(Get FASTA)	NCBI Sequence Viewer
	EDL89381	(Get FASTA)	NCBI Sequence Viewer
	EDL89382	(Get FASTA)	NCBI Sequence Viewer
	EDL89383	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029601
GenBank Protein	Q7TMB0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_853665 ⟸ NM_181634

- UniProtKB:

Q7TMB0 (UniProtKB/Swiss-Prot), B3DM92 (UniProtKB/TrEMBL), F1LMM6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MIAKKEKNKTPKDSMTLLPCFYFVELPIVASSVVSLYFLELTDLFQPAKVGFQCHDRSLSMPYV
ETNEELIPLLMLLSLAFAAPAASIMVGEGMVYCLQSRLWGRGPGGVEGSINAGGCNFNSFLRRT
VRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCEANPYITQDICSGHDTH
AILSARKTFPSQHATLSAFAAVYVSMYFNSVISDATKLLKPILVFAFAIAAGVCGLTQITQYRS
HPVDVYAGFLIGAGIAAYLACHAVGNFQASPAEKVPAPAPAKDALRVLTQRGHESMYQQNKSVS
TDELGPPGRLEGVPRPVAREKTSLGSLKRASVDVDLLAPRSPMGKEGMVTFSNTLPRVSTPSLD
DPSRRHMTIHVPLDASRSRQLISEWKQKSLEGRGLGLPDEASPAHLRAPAEQVAEEEEEEEEEE
EEEEEEEEEEEGPVPPSLYPTVQARPGLGPRVILPPRPGPQPLIHIPEEVVQAGAGLSPKSSAS
VRAKWLSMVEKGGGPVAVAPPQPRVANPPRLLQVIAMSKAAGGPKAETASSSSASSDSSQYRSP
SDRDSASIVTIDAHAPHHPVVHLSAGSTPWEWKAKVVEGEGGYELGDLARGFRSSCKQPGIGPG
SPVSDVDQEEPRFGAVATVNLATGEGLPPPGASEGALGAGSRESTLRRQVGALGEREVEAEAES
YYRRMQARRYQD

hide sequence

Ensembl Acc Id:

ENSRNOP00000029601 ⟸ ENSRNOT00000031315

Ensembl Acc Id:

ENSRNOP00000076351 ⟸ ENSRNOT00000093196

Ensembl Acc Id:

ENSRNOP00000084313 ⟸ ENSRNOT00000094347

RefSeq Acc Id:	XP_063119480 ⟸ XM_063263410
- Peptide Label:	isoform X1
- UniProtKB:	Q7TMB0 (UniProtKB/Swiss-Prot), B3DM92 (UniProtKB/TrEMBL), F1LMM6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000108014 ⟸ ENSRNOT00000134760

Protein Domains

Phosphatidic acid phosphatase type 2/haloperoxidase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TMB0-F1-model_v2	AlphaFold	Q7TMB0	1-716	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727823	AgrOrtholog
BioCyc Gene	G2FUF-34893	BioCyc
Ensembl Genes	ENSRNOG00000027940	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000031315	ENTREZGENE
Gene3D-CATH	Phosphatidic acid phosphatase type 2/haloperoxidase	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:8366697	IMAGE-MGC_LOAD
InterPro	P_Acid_Pase_2/haloperoxi_sf	UniProtKB/Swiss-Prot
	P_Acid_Pase_2/haloperoxidase	UniProtKB/Swiss-Prot
	PLPP	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:187308	IMAGE-MGC_LOAD
NCBI Gene	314614	ENTREZGENE
PANTHER	PTHR10165	UniProtKB/Swiss-Prot
	PTHR10165:SF14	UniProtKB/Swiss-Prot
Pfam	PAP2	UniProtKB/Swiss-Prot
PhenoGen	Plppr3	PhenoGen
RatGTEx	ENSRNOG00000027940	RatGTEx
SMART	acidPPc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48317	UniProtKB/Swiss-Prot
UniProt	A0A8I6GBP5_RAT	UniProtKB/TrEMBL
	A0ABK0LBQ7_RAT	UniProtKB/TrEMBL
	B3DM92	ENTREZGENE, UniProtKB/TrEMBL
	F1LMM6	ENTREZGENE
	PLPR3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-10-26	Plppr3	phospholipid phosphatase related 3	Lppr3	lipid phosphate phosphatase-related protein type 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-05-24	Lppr3	lipid phosphate phosphatase-related protein type 3	LOC100363739	plasticity-related protein PRG-2-like	Data merged from RGD:2322412	1643240	APPROVED
2010-05-06	LOC100363739	plasticity-related protein PRG-2-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2009-11-02	Lppr3	lipid phosphate phosphatase-related protein type 3	Prg-2	plasticity-related gene 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-07-23	Prg-2	plasticity-related gene 2	Prg-2	plasticity-related protein PRG-2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-09-30	Prg-2				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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