Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Astn1 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of ASTN1 mRNA | CTD | PMID:20188158 | Astn1 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Astn1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of ASTN1 mRNA | CTD | PMID:30951980 | Astn1 | Rat | acrylamide | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ASTN1 mRNA | CTD | PMID:32763439 | Astn1 | Rat | aflatoxin B1 | decreases methylation | ISO | ASTN1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ASTN1 gene | CTD | PMID:27153756 | Astn1 | Rat | all-trans-retinoic acid | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ASTN1 mRNA | CTD | PMID:21934132 | Astn1 | Rat | antirheumatic drug | increases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ASTN1 mRNA | CTD | PMID:24449571 | Astn1 | Rat | arsane | affects methylation | ISO | ASTN1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ASTN1 gene | CTD | PMID:25304211 | Astn1 | Rat | arsenic atom | affects methylation | ISO | ASTN1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ASTN1 gene | CTD | PMID:25304211 | Astn1 | Rat | belinostat | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | belinostat results in decreased expression of ASTN1 mRNA | CTD | PMID:26272509 | Astn1 | Rat | benzo[a]pyrene | increases methylation | ISO | Astn1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of ASTN1 intron | CTD | PMID:27901495 | Astn1 | Rat | benzo[a]pyrene | increases methylation | ISO | ASTN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ASTN1 3' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Astn1 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ASTN1 mRNA | CTD | PMID:31163220 | Astn1 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of ASTN1 mRNA | CTD | PMID:34319233 | Astn1 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Astn1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ASTN1 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 | Astn1 | Rat | bisphenol A | decreases expression | ISO | Astn1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ASTN1 mRNA | CTD | PMID:32156529 | Astn1 | Rat | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Astn1 | Rat | cisplatin | affects response to substance | ISO | ASTN1 (Homo sapiens) | 6480464 | ASTN1 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | Astn1 | Rat | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Astn1 | Rat | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Astn1 | Rat | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Astn1 | Rat | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Astn1 | Rat | diquat | decreases expression | ISO | Astn1 (Mus musculus) | 6480464 | Diquat results in decreased expression of ASTN1 mRNA | CTD | PMID:36851058 | Astn1 | Rat | dorsomorphin | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Astn1 | Rat | entinostat | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Astn1 | Rat | entinostat | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of ASTN1 mRNA | CTD | PMID:26272509 | Astn1 | Rat | ethanol | affects splicing | ISO | Astn1 (Mus musculus) | 6480464 | Ethanol affects the splicing of ASTN1 mRNA | CTD | PMID:30319688 | Astn1 | Rat | ethanol | increases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Ethanol results in increased expression of ASTN1 mRNA | CTD | PMID:31059573 | Astn1 | Rat | ethanol | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | Ethanol results in increased expression of ASTN1 mRNA | CTD | PMID:30319688 | Astn1 | Rat | genistein | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | Genistein results in increased expression of ASTN1 mRNA | CTD | PMID:32186404 | Astn1 | Rat | glyphosate | increases expression | EXP | | 6480464 | Glyphosate results in increased expression of ASTN1 mRNA | CTD | PMID:38314887 | Astn1 | Rat | GW 4064 | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | GW 4064 results in increased expression of ASTN1 mRNA | CTD | PMID:26655953 | Astn1 | Rat | mercury dibromide | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of ASTN1 mRNA | CTD | PMID:26272509 | Astn1 | Rat | mercury dibromide | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Astn1 | Rat | methylmercury chloride | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ASTN1 mRNA | CTD | PMID:28001369 | Astn1 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of ASTN1 mRNA | CTD | PMID:36314267 | Astn1 | Rat | okadaic acid | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of ASTN1 mRNA | CTD | PMID:38832940 | Astn1 | Rat | panobinostat | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of ASTN1 mRNA | CTD | PMID:26272509 | Astn1 | Rat | panobinostat | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Astn1 | Rat | paracetamol | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of ASTN1 mRNA | CTD | PMID:17585979 | Astn1 | Rat | paracetamol | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ASTN1 mRNA | CTD | PMID:22230336 | Astn1 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of ASTN1 mRNA | CTD | PMID:32680482 | Astn1 | Rat | phenylmercury acetate | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of ASTN1 mRNA | CTD | PMID:26272509 | Astn1 | Rat | phenylmercury acetate | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Astn1 | Rat | pirinixic acid | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of ASTN1 mRNA | CTD | PMID:20813756 | Astn1 | Rat | SB 431542 | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Astn1 | Rat | sodium arsenite | decreases expression | ISO | Astn1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of ASTN1 mRNA | CTD | PMID:36209798 | Astn1 | Rat | sodium arsenite | increases expression | ISO | Astn1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of ASTN1 mRNA | CTD | PMID:37682722 | Astn1 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ASTN1 mRNA | CTD | PMID:19281266 | Astn1 | Rat | titanium dioxide | decreases methylation | ISO | Astn1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of ASTN1 gene | CTD | PMID:35295148 | Astn1 | Rat | trichostatin A | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ASTN1 mRNA | CTD | PMID:24935251|PMID:26272509 | Astn1 | Rat | trichostatin A | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Astn1 | Rat | trimellitic anhydride | decreases expression | ISO | Astn1 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of ASTN1 mRNA | CTD | PMID:19042947 | Astn1 | Rat | valproic acid | affects expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ASTN1 mRNA | CTD | PMID:25979313 | Astn1 | Rat | valproic acid | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ASTN1 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:26272509|PMID:28001369 | Astn1 | Rat | valproic acid | multiple interactions | ISO | ASTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Astn1 | Rat | vorinostat | decreases expression | ISO | ASTN1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of ASTN1 mRNA | CTD | PMID:27188386 | | 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