Tfb1m (transcription factor B1, mitochondrial) - Rat Genome Database

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Gene: Tfb1m (transcription factor B1, mitochondrial) Rattus norvegicus
Analyze
Symbol: Tfb1m
Name: transcription factor B1, mitochondrial
RGD ID: 727795
Description: Predicted to enable S-adenosyl-L-methionine binding activity; mitochondrial transcription factor activity; and rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in rRNA methylation and transcription initiation at mitochondrial promoter. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrial matrix. Orthologous to human TFB1M (transcription factor B1, mitochondrial); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dimethyladenosine transferase 1, mitochondrial; mitochondrial 12S rRNA dimethylase 1; mitochondrial transcription factor B1; mtTFB1; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8146,520,510 - 46,567,004 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl146,524,435 - 46,566,948 (-)EnsemblGRCr8
mRatBN7.2144,115,240 - 44,161,737 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl144,119,166 - 44,161,709 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx144,660,116 - 44,702,630 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,647,350 - 50,689,863 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,735,618 - 44,778,128 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0144,433,116 - 44,474,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,433,116 - 44,474,674 (-)Ensemblrn6Rnor6.0
Rnor_5.0145,762,960 - 45,804,760 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4138,513,709 - 38,556,210 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera139,753,776 - 39,795,383 (-)NCBICelera
RGSC_v3.1138,516,653 - 38,559,155 (-)NCBI
Cytogenetic Map1q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dimethyl fumarate  (ISO)
dimethyl sulfoxide  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
GSK-J4  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
potassium chromate  (ISO)
Ptaquiloside  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP)
teriflunomide  (ISO)
tetrathiomolybdate(2-)  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
Triptolide  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. Falkenberg M, etal., Nat Genet 2002 Jul;31(3):289-94.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:12496758   PMID:15489334   PMID:18063578   PMID:18614015   PMID:22658674   PMID:23303773   PMID:34800366  


Genomics

Comparative Map Data
Tfb1m
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8146,520,510 - 46,567,004 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl146,524,435 - 46,566,948 (-)EnsemblGRCr8
mRatBN7.2144,115,240 - 44,161,737 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl144,119,166 - 44,161,709 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx144,660,116 - 44,702,630 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,647,350 - 50,689,863 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,735,618 - 44,778,128 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0144,433,116 - 44,474,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,433,116 - 44,474,674 (-)Ensemblrn6Rnor6.0
Rnor_5.0145,762,960 - 45,804,760 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4138,513,709 - 38,556,210 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera139,753,776 - 39,795,383 (-)NCBICelera
RGSC_v3.1138,516,653 - 38,559,155 (-)NCBI
Cytogenetic Map1q11NCBI
TFB1M
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386155,229,871 - 155,314,484 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6155,256,134 - 155,314,493 (-)Ensemblhg38GRCh38
GRCh376155,551,005 - 155,635,618 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366155,620,482 - 155,677,318 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346155,670,910 - 155,727,731NCBI
Celera6156,313,087 - 156,369,927 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6153,139,544 - 153,197,988 (-)NCBIHuRef
CHM1_16155,839,879 - 155,897,947 (-)NCBICHM1_1
T2T-CHM13v2.06156,431,886 - 156,516,508 (-)NCBIT2T-CHM13v2.0
Tfb1m
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39173,569,119 - 3,608,064 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl173,569,531 - 3,608,056 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38173,519,250 - 3,557,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl173,519,256 - 3,557,781 (-)Ensemblmm10GRCm38
MGSCv37173,519,256 - 3,557,713 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36173,475,738 - 3,514,195 (-)NCBIMGSCv36mm8
Celera174,054,051 - 4,093,093 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map172.01NCBI
Tfb1m
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554396,883,852 - 6,943,152 (+)Ensembl
ChiLan1.0NW_0049554396,889,432 - 6,943,152 (+)NCBIChiLan1.0ChiLan1.0
TFB1M
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25175,281,025 - 175,337,446 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16173,171,102 - 173,228,972 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06153,072,906 - 153,130,545 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16159,034,430 - 159,094,588 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6159,037,203 - 159,094,592 (-)EnsemblpanPan2panpan1.1
TFB1M
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1145,001,095 - 45,071,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl145,001,088 - 45,071,518 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha145,838,091 - 45,908,486 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0145,184,445 - 45,255,052 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl145,182,619 - 45,255,027 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1145,051,617 - 45,121,984 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0144,923,363 - 44,993,740 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0145,479,603 - 45,549,987 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tfb1m
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946140,210,776 - 140,258,128 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364897,464,663 - 7,510,123 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364897,464,550 - 7,510,108 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFB1M
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl111,566,245 - 11,653,871 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1111,566,193 - 11,650,656 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,558,903 - 13,622,456 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TFB1M
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11382,823,528 - 82,877,958 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1382,823,640 - 82,877,923 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604055,194,167 - 55,253,100 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfb1m
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247853,027,230 - 3,085,879 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247853,027,662 - 3,085,879 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tfb1m
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12195,204,374 - 195,244,701 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tfb1m
415 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:70
Count of miRNA genes:56
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000022397
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000078768   ⟹   ENSRNOP00000070930
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl146,524,435 - 46,566,948 (-)Ensembl
mRatBN7.2 Ensembl144,119,166 - 44,161,709 (-)Ensembl
Rnor_6.0 Ensembl144,433,116 - 44,474,674 (-)Ensembl
RefSeq Acc Id: NM_181474   ⟹   NP_852139
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,524,435 - 46,566,948 (-)NCBI
mRatBN7.2144,119,165 - 44,161,680 (-)NCBI
Rnor_6.0144,433,116 - 44,474,674 (-)NCBI
Rnor_5.0145,762,960 - 45,804,760 (-)NCBI
RGSC_v3.4138,513,709 - 38,556,210 (-)RGD
Celera139,753,776 - 39,795,383 (-)RGD
Sequence:
RefSeq Acc Id: XM_039110653   ⟹   XP_038966581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,526,815 - 46,567,004 (-)NCBI
mRatBN7.2144,121,550 - 44,161,737 (-)NCBI
RefSeq Acc Id: XM_039110661   ⟹   XP_038966589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,542,307 - 46,567,002 (-)NCBI
mRatBN7.2144,136,254 - 44,161,734 (-)NCBI
RefSeq Acc Id: XM_039110671   ⟹   XP_038966599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,520,510 - 46,564,275 (-)NCBI
mRatBN7.2144,115,240 - 44,161,711 (-)NCBI
RefSeq Acc Id: XR_005504530
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,526,817 - 46,567,002 (-)NCBI
mRatBN7.2144,121,545 - 44,161,734 (-)NCBI
RefSeq Acc Id: NP_852139   ⟸   NM_181474
- UniProtKB: Q6IRI6 (UniProtKB/Swiss-Prot),   Q811P6 (UniProtKB/Swiss-Prot),   A0A0G2JZ68 (UniProtKB/TrEMBL),   A6KIQ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070930   ⟸   ENSRNOT00000078768
RefSeq Acc Id: XP_038966599   ⟸   XM_039110671
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038966581   ⟸   XM_039110653
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038966589   ⟸   XM_039110661
- Peptide Label: isoform X2
Protein Domains
Ribosomal RNA adenine methylase transferase N-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q811P6-F1-model_v2 AlphaFold Q811P6 1-345 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689601
Promoter ID:EPDNEW_R124
Type:initiation region
Name:Tfb1m_1
Description:transcription factor B1, mitochondrial
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0144,474,694 - 44,474,754EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727795 AgrOrtholog
BioCyc Gene G2FUF-61664 BioCyc
Ensembl Genes ENSRNOG00000056223 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000078768 ENTREZGENE
Gene3D-CATH 1.10.8.100 UniProtKB/Swiss-Prot
  3.40.50.150 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7102927 IMAGE-MGC_LOAD
InterPro KsgA/Erm UniProtKB/Swiss-Prot
  rRNA_Ade_diMease-like UniProtKB/Swiss-Prot
  rRNA_Ade_Mease_Trfase_CS UniProtKB/Swiss-Prot
  rRNA_Ade_methylase_Trfase_N UniProtKB/Swiss-Prot
  rRNA_adenine_dimethylase UniProtKB/Swiss-Prot
  SAM-dependent_MTases UniProtKB/Swiss-Prot
KEGG Report rno:308140 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91415 IMAGE-MGC_LOAD
NCBI Gene 308140 ENTREZGENE
PANTHER DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR11727 UniProtKB/Swiss-Prot
Pfam RrnaAD UniProtKB/Swiss-Prot
PhenoGen Tfb1m PhenoGen
PROSITE RRNA_A_DIMETH UniProtKB/Swiss-Prot
  SAM_RNA_A_N6_MT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000056223 RatGTEx
SMART rADc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot
UniProt A0A0G2JZ68 ENTREZGENE, UniProtKB/TrEMBL
  A6KIQ6 ENTREZGENE, UniProtKB/TrEMBL
  Q6IRI6 ENTREZGENE
  Q811P6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6IRI6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Tfb1m  transcription factor B1, mitochondrial      Symbol and Name status set to approved 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein in humans, tfb1m is at least one order of magnitude less active than tfb2m 1302396